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M. smegmatis MC2 155 MSMEG_3116 (-)

annotation: inositol-1-monophosphatase
coordinates: 3190268 - 3191017
length: 249

VTHPADTELRRLAVKAAERGADVCLRHLGELVSVATKSAAGDVVTAVDRAAEEAVRAVLREARPDDSMLG
EEIAEHTGSGPLQWVIDPLDGTTNYTRRIPYFATSVAVRRVSDGTWLAGAVCAPALGSTWSAARGEGARL
DSITQSAQLPLQLIDSTARLVGTGLSYDPGLRRRQLRDLGALVCEYTDMRRFGAAAVDLCLVAQGSLDAF
VEADLAVHDWAAGALIAEEAGAEVTRPCAEGDPVSARWR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_3116--100% (249)inositol-1-monophosphatase
M. smegmatis MC2 155MSMEG_2762-1e-4041.41% (256) inositol-1-monophosphatase
M. smegmatis MC2 155MSMEG_2083-6e-2333.62% (235) inositol monophosphatase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2720csuhB2e-3140.85% (213) extragenic suppressor protein SuhB
M. gilvum PYR-GCKMflv_3937-7e-4247.39% (211) inositol-phosphate phosphatase
M. tuberculosis H37RvRv2701csuhB2e-3140.85% (213) extragenic suppressor protein SuhB
M. leprae Br4923MLBr_01024suhB1e-3341.36% (220) putative inositol monophosphatase
M. abscessus ATCC 19977MAB_3007c-4e-3640.57% (244) inositol-1-monophosphatase SuhB
M. marinum MMMAR_2013suhB6e-3439.26% (242) extragenic suppressor protein SuhB
M. avium 104MAV_3593-1e-3341.67% (216) inositol-1-monophosphatase
M. thermoresistible (build 8)TH_0825suhB3e-3338.25% (251) POSSIBLE EXTRAGENIC SUPPRESSOR PROTEIN SUHB
M. ulcerans Agy99MUL_3339suhB4e-3439.26% (242) extragenic suppressor protein SuhB
M. vanbaalenii PYR-1Mvan_2463-1e-3845.91% (220) inositol-phosphate phosphatase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_2013|M.marinum_M               -------------------MTRPDNDPARLRVVAETLAAEAAEFVRSRRA
MUL_3339|M.ulcerans_Agy99           -------------------MTRPDNDPARLRVVAETLAAEAAEFVRSRRA
Mb2720c|M.bovis_AF2122/97           -------------------MTRPDNEPARLRSVAENLAAEAAAFVRGRRA
Rv2701c|M.tuberculosis_H37Rv        -------------------MTRPDNEPARLRSVAENLAAEAAAFVRGRRA
MLBr_01024|M.leprae_Br4923          -------------------MTVPDNDPEQLRCVAESLATEAAAFVRCRRA
MAV_3593|M.avium_104                ---------------------------MRLRSVAETLAAEAAAFVRRRRA
Mflv_3937|M.gilvum_PYR-GCK          MGPDGRRCAAMDG----VNTMHAADAPVRLQEVAERLAAEAAQFVRRRRV
Mvan_2463|M.vanbaalenii_PYR-1       MGASRASRAARPGRMCCDERVNIDTDPVRLRAVAEQLASEAAEFVGRRRT
TH_0825|M.thermoresistible__bu      -------------------MTSAPVDLTELRAVAERLAAEAADFVRRRRA
MAB_3007c|M.abscessus_ATCC_199      ----------------------MGIEAGALRSVAVRLASEAAEFVRHRRG
MSMEG_3116|M.smegmatis_MC2_155      -------------------MTHP--ADTELRRLAVKAAERGADVCLRHLG
                                                                 *: :*   * ..* .   :  

MMAR_2013|M.marinum_M               ELFG---AHPAAADESD----AVRAKSTPTDPVTVVDTDAERLLRSRLAQ
MUL_3339|M.ulcerans_Agy99           ELFG---AHPAAADESD----AVRAKSTPTDPVTVVDTDAERLLRSRLAQ
Mb2720c|M.bovis_AF2122/97           EVFG---IS-RAGDGDG----AVRAKSSPTDPVTVVDTDTERLLRDRLAQ
Rv2701c|M.tuberculosis_H37Rv        EVFG---IS-RAGDGDG----AVRAKSSPTDPVTVVDTDTERLLRDRLAQ
MLBr_01024|M.leprae_Br4923          EVFGTD-LG---AAGGG----AVRAKSTPTDPVTVVDTETERLLRDRLAQ
MAV_3593|M.avium_104                EVFGTE-PGGASAPDGG----AVRSKSTPTDPVTVVDTETERLLRDRLAQ
Mflv_3937|M.gilvum_PYR-GCK          EVFGDG-SAGAAPDTAQ---PSVRAKSTPTDPVTIVDTETERLLRDRLGQ
Mvan_2463|M.vanbaalenii_PYR-1       EVFG----AGAAPGGAQ---SAVRAKSSPTDPVTVVDTETERLLRDRLAE
TH_0825|M.thermoresistible__bu      EVFGDTGATGASTGSATESGPAVRSKSTPTDPVTIVDTETERLLRDRLTR
MAB_3007c|M.abscessus_ATCC_199      TVDW----------TAS-----VRTKSSETDPVTLVDTDCERLLRRRLAS
MSMEG_3116|M.smegmatis_MC2_155      ELVS------------------VATKSAAGDVVTAVDRAAEEAVRAVLRE
                                     :                    * :**:  * ** **   *. :*  *  

MMAR_2013|M.marinum_M               LRPGDPIVGEEGG----GPADSAPAPDDAVTWVLDPIDGTVNFVYGIPAY
MUL_3339|M.ulcerans_Agy99           LRPGDPIVGEEGG----GPADSAPAPDDAVTWVLDPIDGTVNFVYGIPAY
Mb2720c|M.bovis_AF2122/97           LRPGDPILGEEGG----GPADVTATPSDRVTWVLDPIDGTVNFVYGIPAY
Rv2701c|M.tuberculosis_H37Rv        LRPGDPILGEEGG----GPADVTATPSDRVTWVLDPIDGTVNFVYGIPAY
MLBr_01024|M.leprae_Br4923          LRPGDSILGEEGG----GPADLTATPADTVTWVLDPIDGTVNFVYGIPAY
MAV_3593|M.avium_104                LRPGEPILGEEGG----GPAEPSAPGDGTVTWVLDPIDGTVNFVYGIPAY
Mflv_3937|M.gilvum_PYR-GCK          LRPDDAILGEEEG----GSVDIAE---GRLTWVLDPIDGTVNFLYGIPAY
Mvan_2463|M.vanbaalenii_PYR-1       LRPGDAILGEEEG----GSVDVAD---GRLTWVLDPIDGTVNFLYGIPAY
TH_0825|M.thermoresistible__bu      LRPGEPILGEEGG----QSGAAER---GRPVWVLDPIDGTVNFVYGIEAY
MAB_3007c|M.abscessus_ATCC_199      LRPDDAILGEEDGESAGGSLSGRSGQPSGVRWVIDPIDGTVNFVYGIPAY
MSMEG_3116|M.smegmatis_MC2_155      ARPDDSMLGEEIA---------EHTGSGPLQWVIDPLDGTTNYTRRIPYF
                                     **.:.::*** .              .   **:**:***.*:   *  :

MMAR_2013|M.marinum_M               AVSIGAQ--VGGVSVAGAVADVVGRSVYSAALGQGAHVTDQ-QGTRELHC
MUL_3339|M.ulcerans_Agy99           AVSIGAQ--VGGVSVAGAVADVVGRSVYSAALGQGAHVTDE-QGTRELRC
Mb2720c|M.bovis_AF2122/97           AVSIGAQ--VGGITVAGAVADVAARTVYSAATGLGAHLTDE-RGRHVLRC
Rv2701c|M.tuberculosis_H37Rv        AVSIGAQ--VGGITVAGAVADVAARTVYSAATGLGAHLTDE-RGRHVLRC
MLBr_01024|M.leprae_Br4923          AVSVAAQ--VDGVSVAGAVAEVVAGRVHSAASGLGAHVTDE-YGVQVLRC
MAV_3593|M.avium_104                AVSVGAQ--VDGESVAGAVADVVGDRVYSAAAGLGAHVSDG-AGRQPLQC
Mflv_3937|M.gilvum_PYR-GCK          GVSVGVR--RDGVSVAGAVADVAAGAVYSAALGHGARLSRD-GVATELHV
Mvan_2463|M.vanbaalenii_PYR-1       AVSVGVR--RDGVSVAGAVADVAAGAVYSAALGHGAGVRRG-GVLTPLRC
TH_0825|M.thermoresistible__bu      AVSVGVQ--IDGESVAGAVADVAAGAVYSAARGHGAHLHRD-GVTRRLRC
MAB_3007c|M.abscessus_ATCC_199      AVSVAAQ--VGGVTVAGAVADVVADRVFSAASGAGATVREANGLQRPLAC
MSMEG_3116|M.smegmatis_MC2_155      ATSVAVRRVSDGTWLAGAVCAPALGSTWSAARGEGARLDSI--TQSAQLP
                                    ..*:..:   .*  :****.  .   . *** * ** :            

MMAR_2013|M.marinum_M               TAVEDLSMALLGTGFGYSAGRRATQAALLARMLPMVRDVRRIGSAALDLC
MUL_3339|M.ulcerans_Agy99           TAVEDLSMALLGTGFGYSAGRRATQAALLARMLPMVRDVRRIGSAALDLC
Mb2720c|M.bovis_AF2122/97           TGVDELSMALLGTGFGYSVRCREKQAELLAHVVPLVRDVRRIGSAALDLC
Rv2701c|M.tuberculosis_H37Rv        TGVDELSMALLGTGFGYSVRCREKQAELLAHVVPLVRDVRRIGSAALDLC
MLBr_01024|M.leprae_Br4923          SAVDDLSMALLGTGFAYSVVRRAAQAALLAQMLPVVRDVRRIGSAALDLC
MAV_3593|M.avium_104                AAVDDVSMALLGTGFGYARQRRAAQAALLARMLPVVRDVRRIGSAALDLC
Mflv_3937|M.gilvum_PYR-GCK          TSATDLSMALVGTGFSYDRAHREQQGRIIARLLPEVRDLRRMGSCALDLC
Mvan_2463|M.vanbaalenii_PYR-1       TAATDLSMALVGTGFSYEREHRQRQGEIAARLLPDVRDVRRMGSCALDLC
TH_0825|M.thermoresistible__bu      SAATELSMALVGTGFAYSAELRRSQARIVATLLPRVRDIRRIGSCALDLC
MAB_3007c|M.abscessus_ATCC_199      NPVRETRLALVATGFAYSTVRRERQAHLVAQLLPRVRDVRRIGSAALDLC
MSMEG_3116|M.smegmatis_MC2_155      LQLIDSTARLVGTGLSYDPGLRRRQLRDLGALVCEYTDMRRFGAAAVDLC
                                        :    *:.**:.*    *  *    . ::    *:**:*:.*:***

MMAR_2013|M.marinum_M               MVAAGRLDAYYEHGLQLWDRAAGALIAAEAGARVVLPASDV--VGAG-LV
MUL_3339|M.ulcerans_Agy99           MVAAGRLDAYYEHGLQLWDRAAGALIAAEAGARVVLPASDV--VGAG-LV
Mb2720c|M.bovis_AF2122/97           MVAAGRLDAYYEHGVQVWDCAAGALIAAEAGARVLLSTPRA--GGAGLVV
Rv2701c|M.tuberculosis_H37Rv        MVAAGRLDAYYEHGVQVWDCAAGALIAAEAGARVLLSTPRA--GGAGLVV
MLBr_01024|M.leprae_Br4923          MVAAGQLDAYYEHEVQVWDCAAGALIAAEAGACVQLPKRNGPVGGAG-LV
MAV_3593|M.avium_104                MVAAGRLDAYYEHGLKVWDRAAGALIAAEAGARVVLPAPDG--DGAG-LV
Mflv_3937|M.gilvum_PYR-GCK          AVAAGRLDAYFEDDVHLWDWAAGALIASEAGALVRPPRTED---GSG-LM
Mvan_2463|M.vanbaalenii_PYR-1       AVAAGRLDAYYEDDVHLWDWAAAALIATEAGAHVRPPATGD---GAG-LM
TH_0825|M.thermoresistible__bu      MVAAGLLDAYYEEGVQVWDWAAAXXXVSGGGGGLLGRGAVD---GR----
MAB_3007c|M.abscessus_ATCC_199      AVAEGRVDAQYEHGLGPWDWAAGALIAREAGAVVILPGPDTR-SAAGALI
MSMEG_3116|M.smegmatis_MC2_155      LVAQGSLDAFVEADLAVHDWAAGALIAEEAGAEVTRPCAEG---------
                                     ** * :**  *  :   * **.   .  .*. :                

MMAR_2013|M.marinum_M               VAAAPGVADELLGVLKRLNALEPLD-
MUL_3339|M.ulcerans_Agy99           VAAAPGVADELLGVLKRLNALEPLD-
Mb2720c|M.bovis_AF2122/97           VAAAPGIADELLAALQRFNGLEPIPD
Rv2701c|M.tuberculosis_H37Rv        VAAAPGIADELLAALQRFNGLEPIPD
MLBr_01024|M.leprae_Br4923          VAAAPGIADALLAALQRFNGLAPILD
MAV_3593|M.avium_104                LAAAPGIADELLAVLERFDGLDPILD
Mflv_3937|M.gilvum_PYR-GCK          VAAAPGISVALDEALARSGAL-----
Mvan_2463|M.vanbaalenii_PYR-1       VAAAPGISAAFDAALIRCGAVGG---
TH_0825|M.thermoresistible__bu      ---------------ARRGAGR----
MAB_3007c|M.abscessus_ATCC_199      AATAPGIAGEFGQLLADIGATAPIPG
MSMEG_3116|M.smegmatis_MC2_155      -----------DPVSARWR-------