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MARKPLIAGNWKMNLNHFEAIALVQKIAFALPDKYFDKVDVTVIPPFTDLRSVQTLVDGDKLRLTYGAQD LSQHDSGAYTGEISGAFLAKLGCTFVIVGHSERRTYHGETDELVAAKAKAAHKHGLTPIVCIGEQLEVRE AGNHVEFNVNSLRGSLAGLTPEQIGQTVIAYEPVWAIGTGRVAGAADAQEVCKAIRGELANLSSSEIAAG VRVLYGGSVNAKNVGEIVSQGDVDGALVGGASLDGEQFATLSAIAAGGPLP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3086 | tpiA | - | 100% (261) | triosephosphate isomerase |
| M. smegmatis MC2 155 | MSMEG_6785 | tpiA | 2e-34 | 35.04% (254) | triosephosphate isomerase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1473 | tpiA | 1e-123 | 82.76% (261) | triosephosphate isomerase |
| M. gilvum PYR-GCK | Mflv_3708 | tpiA | 1e-138 | 92.34% (261) | triosephosphate isomerase |
| M. tuberculosis H37Rv | Rv1438 | tpiA | 1e-123 | 82.76% (261) | triosephosphate isomerase |
| M. leprae Br4923 | MLBr_00572 | tpiA | 1e-119 | 80.46% (261) | triosephosphate isomerase |
| M. abscessus ATCC 19977 | MAB_2777c | - | 1e-125 | 83.85% (260) | triosephosphate isomerase (TpiA) |
| M. marinum M | MMAR_2241 | tpiA | 1e-125 | 83.91% (261) | triosephosphate isomerase Tpi |
| M. avium 104 | MAV_3339 | tpiA | 1e-124 | 83.91% (261) | triosephosphate isomerase |
| M. thermoresistible (build 8) | TH_0428 | tpi | 1e-128 | 87.74% (261) | PROBABLE TRIOSEPHOSPHATE ISOMERASE TPI (TIM) |
| M. ulcerans Agy99 | MUL_1830 | tpiA | 1e-125 | 83.91% (261) | triosephosphate isomerase |
| M. vanbaalenii PYR-1 | Mvan_2705 | tpiA | 1e-133 | 88.89% (261) | triosephosphate isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2241|M.marinum_M MSRKPLIAGNWKMNLNHFEAIALVQKIAFSLPDKYYDKVDVTVIPPFTDL
MUL_1830|M.ulcerans_Agy99 MSRKPLIAGNWKMNLNHFEAIALVQKIAFSLPDKYYDKVDVTVIPPFTDL
MAV_3339|M.avium_104 MSRKPLIAGNWKMNLNHFEAIALVQKIAFALPDKYYDKVDVTVLPPFTDL
Mb1473|M.bovis_AF2122/97 MSRKPLIAGNWKMNLNHYEAIALVQKIAFSLPDKYYDRVDVAVIPPFTDL
Rv1438|M.tuberculosis_H37Rv MSRKPLIAGNWKMNLNHYEAIALVQKIAFSLPDKYYDRVDVAVIPPFTDL
MLBr_00572|M.leprae_Br4923 MSRKSLIAGNWKMNLNHFEAIALVQKIAFSLPDKYYDKVDVTVLPPFTDL
MSMEG_3086|M.smegmatis_MC2_155 MARKPLIAGNWKMNLNHFEAIALVQKIAFALPDKYFDKVDVTVIPPFTDL
Mflv_3708|M.gilvum_PYR-GCK MTRKPLIAGNWKMNLNHFEAIALVQKIAFSLPDKYFDRVDVTVIPPFTDL
Mvan_2705|M.vanbaalenii_PYR-1 MSRKPLIAGNWKMNLNHFEAIALVQKIAFSLPDKYFDKVDVTVIPPFTDL
TH_0428|M.thermoresistible__bu VSRKPLIAGNWKMNLNHFEAIALVQKIAFALPAKYFDKVDVAVLPPFTDL
MAB_2777c|M.abscessus_ATCC_199 MSRKPLIAGNWKMNLNHFEAIALVQKIAFSLPDKYFDKVDVTVIPPFTDI
::**.************:***********:** **:*:***:*:*****:
MMAR_2241|M.marinum_M RSVQTLVDGDKLRLTYGGQDLSQHDSGAYTGDISGAFLAKLGCSFVVVGH
MUL_1830|M.ulcerans_Agy99 RSVQTLVDGDKLRLTYGGQDLSQHDSGAYTGDISGAFLAKLGCSFVVVGH
MAV_3339|M.avium_104 RSVQTLVDGDKLRLSYGAQDLSQHDSGAYTGDISGAFLAKLGCTFVVVGH
Mb1473|M.bovis_AF2122/97 RSVQTLVDGDKLRLTYGAQDLSPHDSGAYTGDVSGAFLAKLGCSYVVVGH
Rv1438|M.tuberculosis_H37Rv RSVQTLVDGDKLRLTYGAQDLSPHDSGAYTGDVSGAFLAKLGCSYVVVGH
MLBr_00572|M.leprae_Br4923 RSVQTLVDGDKLRLTYGAQDLSQHDLGAYTGDISGAFLAKLGCSFVLVGH
MSMEG_3086|M.smegmatis_MC2_155 RSVQTLVDGDKLRLTYGAQDLSQHDSGAYTGEISGAFLAKLGCTFVIVGH
Mflv_3708|M.gilvum_PYR-GCK RSVQTLVDGDKLRLTYGAQDVSQHDSGAYTGEISGAFLAKLGCTFAVVGH
Mvan_2705|M.vanbaalenii_PYR-1 RSVQTLVDGDKLRLTYGAQDVSQHDSGAYTGEISGAFLAKLGCTFAVVGH
TH_0428|M.thermoresistible__bu RSVQTLVDGDDLRLTYGAQDLSQHDSGAYTGEISGAFLAKLGCTYVIVGH
MAB_2777c|M.abscessus_ATCC_199 RSVQTLVDGDKLRLTYGAQDLSVYDSGAYTGEVSGAFLAKLGVTYVVVGH
**********.***:**.**:* :* *****::********* ::.:***
MMAR_2241|M.marinum_M SERRTYHNEDDALVAAKAAAALKHDLTPIVCIGEHLDVREAGNHVAHNVE
MUL_1830|M.ulcerans_Agy99 SERRTYHNEDDALVAAKAAAALKHDLTPIVCIGEHLDVREAGNHVAHNVE
MAV_3339|M.avium_104 SERRTYHNEDDALVAAKAAAALKHELTPIICIGEHLEVREAGNHVIHCEE
Mb1473|M.bovis_AF2122/97 SERRTYHNEDDALVAAKAATALKHGLTPIVCIGEHLDVREAGNHVAHNIE
Rv1438|M.tuberculosis_H37Rv SERRTYHNEDDALVAAKAATALKHGLTPIVCIGEHLDVREAGNHVAHNIE
MLBr_00572|M.leprae_Br4923 SERRTYHDEGDALVAAKTAAALKNSLTPIVCIGEYLEIREVGEHVSHCQN
MSMEG_3086|M.smegmatis_MC2_155 SERRTYHGETDELVAAKAKAAHKHGLTPIVCIGEQLEVREAGNHVEFNVN
Mflv_3708|M.gilvum_PYR-GCK SERRTYHGETDELVAAKATAALKHGLTPIVCIGEQLEVREAGNHVEFNVN
Mvan_2705|M.vanbaalenii_PYR-1 SERRTYHNEDDALVAAKAAAAFKHGLTPIICIGEHLDVREAGNHVEYNVN
TH_0428|M.thermoresistible__bu SERRTYHHEDDALVAAKARAAFRHDLIPIVCIGEPLEVREAGNHVAHNLE
MAB_2777c|M.abscessus_ATCC_199 SERRQYHGEDDALVAAKAAAALKHGLTPIVCIGEALDIREAGDHVQYNVN
**** ** * * *****: :* :: * **:**** *::**.*:** . :
MMAR_2241|M.marinum_M QLRGSLSGLSAEQISKVVIAYEPVWAIGTGRVAGAADAQEVCAAIRSELG
MUL_1830|M.ulcerans_Agy99 QLRGSLSGLSAEQISKVVIAYEPVWAIGTGRVAGAADAQEVCAAIRSELG
MAV_3339|M.avium_104 QLRGSLAGLSAEQIGKVVIAYEPVWAIGTGRVASASDAQEVCAAIRKELA
Mb1473|M.bovis_AF2122/97 QLRGSLAGLLAEQIGSVVIAYEPVWAIGTGRVASAADAQEVCAAIRKELA
Rv1438|M.tuberculosis_H37Rv QLRGSLAGLLAEQIGSVVIAYEPVWAIGTGRVASAADAQEVCAAIRKELA
MLBr_00572|M.leprae_Br4923 QLRGSLAGLSPEQIGNVVIVYEPVWAIGTGRVASAADAQEVCEAIRKELG
MSMEG_3086|M.smegmatis_MC2_155 SLRGSLAGLTPEQIGQTVIAYEPVWAIGTGRVAGAADAQEVCKAIRGELA
Mflv_3708|M.gilvum_PYR-GCK SLRGSLAGLSAEQIAQTVIAYEPVWAIGTGRVASAADAQEVCKAIRDELG
Mvan_2705|M.vanbaalenii_PYR-1 QLRGSLAGLSAEQIGQAVIAYEPVWAIGTGRVASAADAQEVCKAIRDELG
TH_0428|M.thermoresistible__bu MLRGSLAGLSAEQIGRAVIAYEPVWAIGTGRVASAADAQEVCKAIRDELG
MAB_2777c|M.abscessus_ATCC_199 SLRGSLAGLSAEQVGKVVIAYEPVWAIGTGRVASAADAQEVCAAIRAELA
*****:** .**:. .**.*************.*:****** *** **.
MMAR_2241|M.marinum_M SLASPQIADAVRVLYGGSVNAKNIGELIAQADVDGGLVGGASLDGEQFAT
MUL_1830|M.ulcerans_Agy99 SLASPQIADAVRVLYGGSVNAKNIGELIAQADVDGGLVGGASLDGEQFAT
MAV_3339|M.avium_104 SLASAQIADSVRVLYGGSVNAKNVGELIAQDDIDGGLVGGASLDGEQFAT
Mb1473|M.bovis_AF2122/97 SLASPRIADTVRVLYGGSVNAKNVGDIVAQDDVDGGLVGGASLDGEHFAT
Rv1438|M.tuberculosis_H37Rv SLASPRIADTVRVLYGGSVNAKNVGDIVAQDDVDGGLVGGASLDGEHFAT
MLBr_00572|M.leprae_Br4923 ALASPQVAETVRVLYGGSLNAKNIGDIVAQQDVDGGLVGGASLDGAQFAT
MSMEG_3086|M.smegmatis_MC2_155 NLSSSEIAAGVRVLYGGSVNAKNVGEIVSQGDVDGALVGGASLDGEQFAT
Mflv_3708|M.gilvum_PYR-GCK NLASADVAAGVRVLYGGSVNAKNVGEIVGQGDVDGALVGGASLDGEQFAT
Mvan_2705|M.vanbaalenii_PYR-1 NLASPELAAGVRVLYGGSVNAKNVGEIVGQADVDGALVGGASLDGEQFSM
TH_0428|M.thermoresistible__bu NLTSPEIAAGVRVLYGGSVNAKNVGEIVAQEDVDGALVGGASLDGEQFAT
MAB_2777c|M.abscessus_ATCC_199 QIANADVAGSVRVLYGGSANAKNVGEIVAQEDVDGALVGGASLDGEQFAQ
::.. :* ******** ****:*:::.* *:**.********* :*:
MMAR_2241|M.marinum_M LAAIAAGGPLP
MUL_1830|M.ulcerans_Agy99 LAAIAAGGPLP
MAV_3339|M.avium_104 LAAIAAGGPLP
Mb1473|M.bovis_AF2122/97 LAAIAAGGPLP
Rv1438|M.tuberculosis_H37Rv LAAIAAGGPLP
MLBr_00572|M.leprae_Br4923 LAVIAAGGPLP
MSMEG_3086|M.smegmatis_MC2_155 LSAIAAGGPLP
Mflv_3708|M.gilvum_PYR-GCK LSAIAAGGPLP
Mvan_2705|M.vanbaalenii_PYR-1 LSAIAAGGPLP
TH_0428|M.thermoresistible__bu LSAIAAGGPLP
MAB_2777c|M.abscessus_ATCC_199 MSAIAAGGPLL
::.*******