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VSRKPLIAGNWKMNLNHYEAIALVQKIAFSLPDKYYDRVDVAVIPPFTDLRSVQTLVDGDKLRLTYGAQD LSPHDSGAYTGDVSGAFLAKLGCSYVVVGHSERRTYHNEDDALVAAKAATALKHGLTPIVCIGEHLDVRE AGNHVAHNIEQLRGSLAGLLAEQIGSVVIAYEPVWAIGTGRVASAADAQEVCAAIRKELASLASPRIADT VRVLYGGSVNAKNVGDIVAQDDVDGGLVGGASLDGEHFATLAAIAAGGPLP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1438 | tpiA | - | 100% (261) | triosephosphate isomerase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1473 | tpiA | 1e-148 | 100.00% (261) | triosephosphate isomerase |
| M. gilvum PYR-GCK | Mflv_3708 | tpiA | 1e-123 | 83.52% (261) | triosephosphate isomerase |
| M. leprae Br4923 | MLBr_00572 | tpiA | 1e-126 | 84.29% (261) | triosephosphate isomerase |
| M. abscessus ATCC 19977 | MAB_2777c | - | 1e-124 | 83.85% (260) | triosephosphate isomerase (TpiA) |
| M. marinum M | MMAR_2241 | tpiA | 1e-135 | 90.42% (261) | triosephosphate isomerase Tpi |
| M. avium 104 | MAV_3339 | tpiA | 1e-134 | 89.27% (261) | triosephosphate isomerase |
| M. smegmatis MC2 155 | MSMEG_3086 | tpiA | 1e-123 | 82.76% (261) | triosephosphate isomerase |
| M. thermoresistible (build 8) | TH_0428 | tpi | 1e-127 | 85.06% (261) | PROBABLE TRIOSEPHOSPHATE ISOMERASE TPI (TIM) |
| M. ulcerans Agy99 | MUL_1830 | tpiA | 1e-136 | 90.42% (261) | triosephosphate isomerase |
| M. vanbaalenii PYR-1 | Mvan_2705 | tpiA | 1e-128 | 85.44% (261) | triosephosphate isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1438|M.tuberculosis_H37Rv MSRKPLIAGNWKMNLNHYEAIALVQKIAFSLPDKYYDRVDVAVIPPFTDL
Mb1473|M.bovis_AF2122/97 MSRKPLIAGNWKMNLNHYEAIALVQKIAFSLPDKYYDRVDVAVIPPFTDL
MMAR_2241|M.marinum_M MSRKPLIAGNWKMNLNHFEAIALVQKIAFSLPDKYYDKVDVTVIPPFTDL
MUL_1830|M.ulcerans_Agy99 MSRKPLIAGNWKMNLNHFEAIALVQKIAFSLPDKYYDKVDVTVIPPFTDL
MAV_3339|M.avium_104 MSRKPLIAGNWKMNLNHFEAIALVQKIAFALPDKYYDKVDVTVLPPFTDL
MLBr_00572|M.leprae_Br4923 MSRKSLIAGNWKMNLNHFEAIALVQKIAFSLPDKYYDKVDVTVLPPFTDL
Mflv_3708|M.gilvum_PYR-GCK MTRKPLIAGNWKMNLNHFEAIALVQKIAFSLPDKYFDRVDVTVIPPFTDL
MSMEG_3086|M.smegmatis_MC2_155 MARKPLIAGNWKMNLNHFEAIALVQKIAFALPDKYFDKVDVTVIPPFTDL
Mvan_2705|M.vanbaalenii_PYR-1 MSRKPLIAGNWKMNLNHFEAIALVQKIAFSLPDKYFDKVDVTVIPPFTDL
TH_0428|M.thermoresistible__bu VSRKPLIAGNWKMNLNHFEAIALVQKIAFALPAKYFDKVDVAVLPPFTDL
MAB_2777c|M.abscessus_ATCC_199 MSRKPLIAGNWKMNLNHFEAIALVQKIAFSLPDKYFDKVDVTVIPPFTDI
::**.************:***********:** **:*:***:*:*****:
Rv1438|M.tuberculosis_H37Rv RSVQTLVDGDKLRLTYGAQDLSPHDSGAYTGDVSGAFLAKLGCSYVVVGH
Mb1473|M.bovis_AF2122/97 RSVQTLVDGDKLRLTYGAQDLSPHDSGAYTGDVSGAFLAKLGCSYVVVGH
MMAR_2241|M.marinum_M RSVQTLVDGDKLRLTYGGQDLSQHDSGAYTGDISGAFLAKLGCSFVVVGH
MUL_1830|M.ulcerans_Agy99 RSVQTLVDGDKLRLTYGGQDLSQHDSGAYTGDISGAFLAKLGCSFVVVGH
MAV_3339|M.avium_104 RSVQTLVDGDKLRLSYGAQDLSQHDSGAYTGDISGAFLAKLGCTFVVVGH
MLBr_00572|M.leprae_Br4923 RSVQTLVDGDKLRLTYGAQDLSQHDLGAYTGDISGAFLAKLGCSFVLVGH
Mflv_3708|M.gilvum_PYR-GCK RSVQTLVDGDKLRLTYGAQDVSQHDSGAYTGEISGAFLAKLGCTFAVVGH
MSMEG_3086|M.smegmatis_MC2_155 RSVQTLVDGDKLRLTYGAQDLSQHDSGAYTGEISGAFLAKLGCTFVIVGH
Mvan_2705|M.vanbaalenii_PYR-1 RSVQTLVDGDKLRLTYGAQDVSQHDSGAYTGEISGAFLAKLGCTFAVVGH
TH_0428|M.thermoresistible__bu RSVQTLVDGDDLRLTYGAQDLSQHDSGAYTGEISGAFLAKLGCTYVIVGH
MAB_2777c|M.abscessus_ATCC_199 RSVQTLVDGDKLRLTYGAQDLSVYDSGAYTGEVSGAFLAKLGVTYVVVGH
**********.***:**.**:* :* *****::********* ::.:***
Rv1438|M.tuberculosis_H37Rv SERRTYHNEDDALVAAKAATALKHGLTPIVCIGEHLDVREAGNHVAHNIE
Mb1473|M.bovis_AF2122/97 SERRTYHNEDDALVAAKAATALKHGLTPIVCIGEHLDVREAGNHVAHNIE
MMAR_2241|M.marinum_M SERRTYHNEDDALVAAKAAAALKHDLTPIVCIGEHLDVREAGNHVAHNVE
MUL_1830|M.ulcerans_Agy99 SERRTYHNEDDALVAAKAAAALKHDLTPIVCIGEHLDVREAGNHVAHNVE
MAV_3339|M.avium_104 SERRTYHNEDDALVAAKAAAALKHELTPIICIGEHLEVREAGNHVIHCEE
MLBr_00572|M.leprae_Br4923 SERRTYHDEGDALVAAKTAAALKNSLTPIVCIGEYLEIREVGEHVSHCQN
Mflv_3708|M.gilvum_PYR-GCK SERRTYHGETDELVAAKATAALKHGLTPIVCIGEQLEVREAGNHVEFNVN
MSMEG_3086|M.smegmatis_MC2_155 SERRTYHGETDELVAAKAKAAHKHGLTPIVCIGEQLEVREAGNHVEFNVN
Mvan_2705|M.vanbaalenii_PYR-1 SERRTYHNEDDALVAAKAAAAFKHGLTPIICIGEHLDVREAGNHVEYNVN
TH_0428|M.thermoresistible__bu SERRTYHHEDDALVAAKARAAFRHDLIPIVCIGEPLEVREAGNHVAHNLE
MAB_2777c|M.abscessus_ATCC_199 SERRQYHGEDDALVAAKAAAALKHGLTPIVCIGEALDIREAGDHVQYNVN
**** ** * * *****: :* :: * **:**** *::**.*:** . :
Rv1438|M.tuberculosis_H37Rv QLRGSLAGLLAEQIGSVVIAYEPVWAIGTGRVASAADAQEVCAAIRKELA
Mb1473|M.bovis_AF2122/97 QLRGSLAGLLAEQIGSVVIAYEPVWAIGTGRVASAADAQEVCAAIRKELA
MMAR_2241|M.marinum_M QLRGSLSGLSAEQISKVVIAYEPVWAIGTGRVAGAADAQEVCAAIRSELG
MUL_1830|M.ulcerans_Agy99 QLRGSLSGLSAEQISKVVIAYEPVWAIGTGRVAGAADAQEVCAAIRSELG
MAV_3339|M.avium_104 QLRGSLAGLSAEQIGKVVIAYEPVWAIGTGRVASASDAQEVCAAIRKELA
MLBr_00572|M.leprae_Br4923 QLRGSLAGLSPEQIGNVVIVYEPVWAIGTGRVASAADAQEVCEAIRKELG
Mflv_3708|M.gilvum_PYR-GCK SLRGSLAGLSAEQIAQTVIAYEPVWAIGTGRVASAADAQEVCKAIRDELG
MSMEG_3086|M.smegmatis_MC2_155 SLRGSLAGLTPEQIGQTVIAYEPVWAIGTGRVAGAADAQEVCKAIRGELA
Mvan_2705|M.vanbaalenii_PYR-1 QLRGSLAGLSAEQIGQAVIAYEPVWAIGTGRVASAADAQEVCKAIRDELG
TH_0428|M.thermoresistible__bu MLRGSLAGLSAEQIGRAVIAYEPVWAIGTGRVASAADAQEVCKAIRDELG
MAB_2777c|M.abscessus_ATCC_199 SLRGSLAGLSAEQVGKVVIAYEPVWAIGTGRVASAADAQEVCAAIRAELA
*****:** .**:. .**.*************.*:****** *** **.
Rv1438|M.tuberculosis_H37Rv SLASPRIADTVRVLYGGSVNAKNVGDIVAQDDVDGGLVGGASLDGEHFAT
Mb1473|M.bovis_AF2122/97 SLASPRIADTVRVLYGGSVNAKNVGDIVAQDDVDGGLVGGASLDGEHFAT
MMAR_2241|M.marinum_M SLASPQIADAVRVLYGGSVNAKNIGELIAQADVDGGLVGGASLDGEQFAT
MUL_1830|M.ulcerans_Agy99 SLASPQIADAVRVLYGGSVNAKNIGELIAQADVDGGLVGGASLDGEQFAT
MAV_3339|M.avium_104 SLASAQIADSVRVLYGGSVNAKNVGELIAQDDIDGGLVGGASLDGEQFAT
MLBr_00572|M.leprae_Br4923 ALASPQVAETVRVLYGGSLNAKNIGDIVAQQDVDGGLVGGASLDGAQFAT
Mflv_3708|M.gilvum_PYR-GCK NLASADVAAGVRVLYGGSVNAKNVGEIVGQGDVDGALVGGASLDGEQFAT
MSMEG_3086|M.smegmatis_MC2_155 NLSSSEIAAGVRVLYGGSVNAKNVGEIVSQGDVDGALVGGASLDGEQFAT
Mvan_2705|M.vanbaalenii_PYR-1 NLASPELAAGVRVLYGGSVNAKNVGEIVGQADVDGALVGGASLDGEQFSM
TH_0428|M.thermoresistible__bu NLTSPEIAAGVRVLYGGSVNAKNVGEIVAQEDVDGALVGGASLDGEQFAT
MAB_2777c|M.abscessus_ATCC_199 QIANADVAGSVRVLYGGSANAKNVGEIVAQEDVDGALVGGASLDGEQFAQ
::.. :* ******** ****:*:::.* *:**.********* :*:
Rv1438|M.tuberculosis_H37Rv LAAIAAGGPLP
Mb1473|M.bovis_AF2122/97 LAAIAAGGPLP
MMAR_2241|M.marinum_M LAAIAAGGPLP
MUL_1830|M.ulcerans_Agy99 LAAIAAGGPLP
MAV_3339|M.avium_104 LAAIAAGGPLP
MLBr_00572|M.leprae_Br4923 LAVIAAGGPLP
Mflv_3708|M.gilvum_PYR-GCK LSAIAAGGPLP
MSMEG_3086|M.smegmatis_MC2_155 LSAIAAGGPLP
Mvan_2705|M.vanbaalenii_PYR-1 LSAIAAGGPLP
TH_0428|M.thermoresistible__bu LSAIAAGGPLP
MAB_2777c|M.abscessus_ATCC_199 MSAIAAGGPLL
::.*******