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SWVFFRHPGQGTRTMVDGSSLLLDLDGVVVESVQRLEDGTRLVQVLTAPQWVGICPECGERSTRSKGWVQ TGPRDVVVGPDRPILRWRKRKWLCPSTVCTRKVFTESVPGIPARARVTPRAKATMATAVLDEDRSVAAVA GQYRCGWHTVHDEVIATAEDALAGELAPVAVLGIDETRRGKAKWEHNPVLGRRVWVDRWDTGLVDITGDQ GLLGQVNGRTSAAVIDWLAGQDPDWRAAITHVAIDLSPAYARVAREALPHAILIADRFHLVKKANDMVDA VRRRVTWTQRGRRGRKADVEWINRRRLLRGSERLTADQRATLFAKLLSADPNQDIAAAWIAKELLRDLLS CADRGGLRYEITTALDRFYRFCAACTVPEVIRLARTIETWQAPIIAALQTGLSNARTEGYNRIVKHVGRI AFGFRNPENQRRRVRWACTRRSRRVTPSRHQRHC*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2830 | - | - | 100% (455) | ISMsm4, transposase |
| M. smegmatis MC2 155 | MSMEG_1239 | - | 0.0 | 100.00% (455) | ISMsm4, transposase |
| M. smegmatis MC2 155 | MSMEG_0430 | - | 0.0 | 100.00% (455) | ISMsm4, transposase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3382c | - | 4e-24 | 48.06% (129) | transposase |
| M. gilvum PYR-GCK | Mflv_3476 | - | 2e-16 | 24.59% (366) | transposase, IS204/IS1001/IS1096/IS1165 family protein |
| M. tuberculosis H37Rv | Rv3349c | - | 4e-24 | 48.06% (129) | transposase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_1440 | - | 4e-23 | 30.17% (295) | ISL3 family transposase |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_3774 | - | 1e-162 | 68.02% (419) | PUTATIVE transposase IstA protein, putative |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2830|M.smegmatis_MC2_155 --------------------------------------------------
TH_3774|M.thermoresistible__bu MLTWEDDVEVHALAKRGWTISAIARHTGFDRKTVRKYLAGDGTPGVRARP
Mb3382c|M.bovis_AF2122/97 --------------------------------------------------
Rv3349c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1440|M.marinum_M --------------------------------------------------
Mflv_3476|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2830|M.smegmatis_MC2_155 --------------------------------------------------
TH_3774|M.thermoresistible__bu GPDPFDPFVDYVTARLTEDPHLWARTLFDELEDLGFGLSYQSLTRNIRTR
Mb3382c|M.bovis_AF2122/97 --------------------------------------------------
Rv3349c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1440|M.marinum_M --------------------------------------------------
Mflv_3476|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2830|M.smegmatis_MC2_155 ---------------------------------------MSWVF------
TH_3774|M.thermoresistible__bu NLRPVCEACRTATGRPNAVIPHPPGEETQWDWLELPDPPASWGWGKTAHL
Mb3382c|M.bovis_AF2122/97 --------------------------------------------------
Rv3349c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1440|M.marinum_M --------------------------------------------------
Mflv_3476|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2830|M.smegmatis_MC2_155 ----FRHPGQG--------------------TR---------------TM
TH_3774|M.thermoresistible__bu LVGSLSHSGKWRGNLAPSEDQPHLVAGLDRVTRGLGGLTRVWRFDRMATV
Mb3382c|M.bovis_AF2122/97 --------------------------------------------------
Rv3349c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1440|M.marinum_M --------------------------------------------------
Mflv_3476|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2830|M.smegmatis_MC2_155 VDGSS---------------------------------------------
TH_3774|M.thermoresistible__bu CDPGSGRVTASFAGVAKHYGVSVAICPPRRGNRKGVVEKVNHTAAQRWWR
Mb3382c|M.bovis_AF2122/97 --------------------------------------------------
Rv3349c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1440|M.marinum_M --------------------------------------------------
Mflv_3476|M.gilvum_PYR-GCK ------------------------------------------MKDAHVVE
MSMEG_2830|M.smegmatis_MC2_155 -----LLLDLDGVVVESVQRLEDGTRL---------------VQVLTAPQ
TH_3774|M.thermoresistible__bu TLADDLTVEAAQASLDRFARVRGDTRLRATADGRSSVAVVAXIYVRTAEQ
Mb3382c|M.bovis_AF2122/97 --------------------------------------------------
Rv3349c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1440|M.marinum_M ----MPDATFACPDLTTFCRLD-ELGLEATGQHLATDRAVLACRITDDGS
Mflv_3476|M.gilvum_PYR-GCK PLGFGVTTPTSTARTTHVRVSTAFNRLLAIPGASVTDVVIGERDVEVTLR
MSMEG_2830|M.smegmatis_MC2_155 WVGICPECGERS----------TRSKGWVQTGPRDVVVGPDRPILRWRKR
TH_3774|M.thermoresistible__bu WVGVCPGCMVRSGVCPGCMVRSARSKGWVSTRPRDIKIGPDIPRIVWRKR
Mb3382c|M.bovis_AF2122/97 --------------------------------------------------
Rv3349c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1440|M.marinum_M WCRRCGE--------------QGTVRDGVTRQLAHEPFGWRPTTLLVTIR
Mflv_3476|M.gilvum_PYR-GCK PTARLLTCPCGK--------RQPSVYDRRRRRWRHLDLGVKRLWLVNEIR
MSMEG_2830|M.smegmatis_MC2_155 KWLCPSTVCTRKVFTESVPGIPARARVTPRAKATMATAVLDEDRSVAAVA
TH_3774|M.thermoresistible__bu KWVCANMCCDRKSFTESVPSIPPRARVTVRAKREMASAVLDDDRSVKAVA
Mb3382c|M.bovis_AF2122/97 --------------------------------------------------
Rv3349c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1440|M.marinum_M RYRCQG--CAHVWRQDSGKAAEPRAKLSRRGLRWALEAIVCRHLSVARIA
Mflv_3476|M.gilvum_PYR-GCK RLNCP----DCGVITEAVPWARPGSRFTRDFEDMVLWLAQRSDR--TTVS
MSMEG_2830|M.smegmatis_MC2_155 GQYRCGWHTVHDEVIATAEDALAGELAPVAVLGIDETRRGKAKWEHNPVL
TH_3774|M.thermoresistible__bu AAYGCTWNTCHDAVIATADPVLAGEPEAVSVLGIDETRRGKAKWETCSQT
Mb3382c|M.bovis_AF2122/97 --------------------------------------------------
Rv3349c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1440|M.marinum_M EALAVSWNTANNAVLAEGRRVLIADPARFDSVAVIG--VDEHVWRHTRRG
Mflv_3476|M.gilvum_PYR-GCK TLMRCAWES----VTAIINRGVAELLDKRRLQTLYRIGVDEICYRHPHR-
MSMEG_2830|M.smegmatis_MC2_155 GRRVWVDRWDTGLVDITGDQGLLGQVNGRTSAAVIDWLAGQDPDWRAAIT
TH_3774|M.thermoresistible__bu GTRSWVDRFDTGLVDITGTGGLLVQVNGRAAKPVTDWLDQRDPGWKATIE
Mb3382c|M.bovis_AF2122/97 --------------------------------------------------
Rv3349c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1440|M.marinum_M DKYVIVIIDLTPVRDKTGPARLLDMVEGRSKKAFQDWLAGRPKQWRDGVE
Mflv_3476|M.gilvum_PYR-GCK ---------YLTIIGDHDTGTVVNIRPGRSEQSLTDFYTAQ-PDSMLKIQ
MSMEG_2830|M.smegmatis_MC2_155 HVAIDLSPAYARVAREA--LPHAILIADRFHLVKKANDMVDAVRRRVTWT
TH_3774|M.thermoresistible__bu FVAIDMSVTYANAARQA--LPHAKLIVDRFHLVKRANEMVDEVRRRTTQA
Mb3382c|M.bovis_AF2122/97 -MAIDPAAAYASAIRTPGLLPNAKLVVDHFHVTTLANDALTAVRRRVTWA
Rv3349c|M.tuberculosis_H37Rv -MAIDPAAAYASAIRTPGLLPNAKLVVDHFHVTTLANDALTAVRRRVTWA
MMAR_1440|M.marinum_M VVAMDGFSGFKTATTEE--LPGAATVMAPFHVVRLAGNALDECRRRVQMD
Mflv_3476|M.gilvum_PYR-GCK AVSMDVSKPYIGATRSK--VPEAIICFDGFHIMRWINRALDAVFSEAAAG
:::* : . :* * **: . : ..
MSMEG_2830|M.smegmatis_MC2_155 QRGRRGRKADVEWINRRRLLRGSERLTADQRATLFAKLLSADPNQDIAAA
TH_3774|M.thermoresistible__bu HRLRRGRKSDPEWINRRRLLRAAERLTDEQRHKLFVKLTSADPNGDIAAA
Mb3382c|M.bovis_AF2122/97 FHDRRGRKIDPQWANRRRLLTARERLSDKSFAKMRNRINAVDPRAQILSA
Rv3349c|M.tuberculosis_H37Rv FHDRRGRKIDPQWANRRRLLTARERLSDKSFAKMRNRINAVDPRAQILSA
MMAR_1440|M.marinum_M TCGHRGRRTDPLYACRRTLQTGADLLTDKQKTRLTALLSCAVG-------
Mflv_3476|M.gilvum_PYR-GCK P--DKVHMSSAQWRTTRWALRTGENRLTDTKRELVNQIAKQNRR--VGRA
: : . : * : . : :
MSMEG_2830|M.smegmatis_MC2_155 WIAKELLRDLLSCADRGGLRYEITTALDRFYRFCAACTVP-------EVI
TH_3774|M.thermoresistible__bu WIAKELLRDVLACTARGGLTYEIRDALYRFYTFCAACSVP-------EIS
Mb3382c|M.bovis_AF2122/97 WIAKEELRTLLSTVRTGGDPHLARHHLHRFLPGASTRRSPNCSPWPPPLT
Rv3349c|M.tuberculosis_H37Rv WIAKEELRTLLSTVRTGGDPHLARHHLHRFLPGASTRRSPNCSPWPPPLT
MMAR_1440|M.marinum_M -----FVLRLNSADPGAGFAMLLAACVAISRFACDGCHSV----------
Mflv_3476|M.gilvum_PYR-GCK WALKEQARDLYRYDHQPG---VARALLKAWITAAKRCRIP-------AFV
: * : .
MSMEG_2830|M.smegmatis_MC2_155 RLARTIETWQAP------IIAALQTGLSNARTEGYNRIVKHVGRIAFGFR
TH_3774|M.thermoresistible__bu KLARTISAWQEP------MILAIQTGLSNARSEGYNRIIKHVGRIAFGFR
Mb3382c|M.bovis_AF2122/97 SHPRSTPSWSPASPTRASVVGEVAEMLGDIDGQCVQVEVPVPERGPAGCG
Rv3349c|M.tuberculosis_H37Rv SHPRSTPSWSPASPTRASVVGEVAEMLGDIDGQCVQVEVPVPERGPAGCG
MMAR_1440|M.marinum_M ---------------------AFGSAWTDDLLPGWW--------------
Mflv_3476|M.gilvum_PYR-GCK ALGKRLAVYFDG------ILAAIELGISNALAESINAKIRLINARGYGHH
. :
MSMEG_2830|M.smegmatis_MC2_155 NPENQRRR----------------VRWACTRRSRRVTPS-RHQRHC-
TH_3774|M.thermoresistible__bu NPENQRRR----------------VRWACTRQSRRTPPSTKQVRPC-
Mb3382c|M.bovis_AF2122/97 GLDGLGRAGVSATPRVCAAMTAVNVAGRCAGQQADVGPTPQHRCRGR
Rv3349c|M.tuberculosis_H37Rv GLDGLGRAGVSATPRVCAAMTAVNVAGRCAGQQADVGPTPQHRCRGR
MMAR_1440|M.marinum_M -----------------------------------------------
Mflv_3476|M.gilvum_PYR-GCK TAETLTSM-----------------IYLCLGGLQVKLPTRT------