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MKDAHVVEPLGFGVTTPTSTARTTHVRVSTAFNRLLAIPGASVTDVVIGERDVEVTLRPTARLLTCPCGK RQPSVYDRRRRRWRHLDLGVKRLWLVNEIRRLNCPDCGVITEAVPWARPGSRFTRDFEDMVLWLAQRSDR TTVSTLMRCAWESVTAIINRGVAELLDKRRLQTLYRIGVDEICYRHPHRYLTIIGDHDTGTVVNIRPGRS EQSLTDFYTAQPDSMLKIQAVSMDVSKPYIGATRSKVPEAIICFDGFHIMRWINRALDAVFSEAAAGPDK VHMSSAQWRTTRWALRTGENRLTDTKRELVNQIAKQNRRVGRAWALKEQARDLYRYDHQPGVARALLKAW ITAAKRCRIPAFVALGKRLAVYFDGILAAIELGISNALAESINAKIRLINARGYGHHTAETLTSMIYLCL GGLQVKLPTRT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3476 | - | - | 100% (431) | transposase, IS204/IS1001/IS1096/IS1165 family protein |
| M. gilvum PYR-GCK | Mflv_1834 | - | 0.0 | 99.77% (432) | transposase, IS204/IS1001/IS1096/IS1165 family protein |
| M. gilvum PYR-GCK | Mflv_0315 | - | 0.0 | 99.54% (432) | transposase, IS204/IS1001/IS1096/IS1165 family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3827 | - | 1e-27 | 40.51% (195) | transposase |
| M. tuberculosis H37Rv | Rv3798 | - | 2e-55 | 34.09% (440) | transposase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_1440 | - | 7e-08 | 24.72% (267) | ISL3 family transposase |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_5398 | - | 6e-17 | 24.82% (407) | ISMsm4, transposase |
| M. thermoresistible (build 8) | TH_3774 | - | 3e-15 | 24.43% (348) | PUTATIVE transposase IstA protein, putative |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5398|M.smegmatis_MC2_155 --------------------------------------------------
TH_3774|M.thermoresistible__bu MLTWEDDVEVHALAKRGWTISAIARHTGFDRKTVRKYLAGDGTPGVRARP
Mb3827|M.bovis_AF2122/97 --------------------------------------------------
Rv3798|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3476|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_1440|M.marinum_M --------------------------------------------------
MSMEG_5398|M.smegmatis_MC2_155 --------------------------------------------------
TH_3774|M.thermoresistible__bu GPDPFDPFVDYVTARLTEDPHLWARTLFDELEDLGFGLSYQSLTRNIRTR
Mb3827|M.bovis_AF2122/97 --------------------------------------------------
Rv3798|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3476|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_1440|M.marinum_M --------------------------------------------------
MSMEG_5398|M.smegmatis_MC2_155 ---------------------------------------MSWVF------
TH_3774|M.thermoresistible__bu NLRPVCEACRTATGRPNAVIPHPPGEETQWDWLELPDPPASWGWGKTAHL
Mb3827|M.bovis_AF2122/97 --------------------------------------------------
Rv3798|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3476|M.gilvum_PYR-GCK -------------------------------------MKDAHVVEPLGFG
MMAR_1440|M.marinum_M ------------------------------------MPDATFAC------
MSMEG_5398|M.smegmatis_MC2_155 ----FRHPGQG--------------------TR---------------TM
TH_3774|M.thermoresistible__bu LVGSLSHSGKWRGNLAPSEDQPHLVAGLDRVTRGLGGLTRVWRFDRMATV
Mb3827|M.bovis_AF2122/97 ----MRNVRLFR------------------------------------AL
Rv3798|M.tuberculosis_H37Rv ----MRNVRLFR------------------------------------AL
Mflv_3476|M.gilvum_PYR-GCK VTTPTSTARTTH------------------------------------VR
MMAR_1440|M.marinum_M ------------------------------------------------PD
MSMEG_5398|M.smegmatis_MC2_155 VDGSS---------------------------------------------
TH_3774|M.thermoresistible__bu CDPGSGRVTASFAGVAKHYGVSVAICPPRRGNRKGVVEKVNHTAAQRWWR
Mb3827|M.bovis_AF2122/97 LGVDKR--------------------------------------------
Rv3798|M.tuberculosis_H37Rv LGVDKR--------------------------------------------
Mflv_3476|M.gilvum_PYR-GCK VSTAFN--------------------------------------------
MMAR_1440|M.marinum_M LTTFCR--------------------------------------------
MSMEG_5398|M.smegmatis_MC2_155 -----LLLDLDGVVVESVQRLEDGTRL---------------VQVLTAPQ
TH_3774|M.thermoresistible__bu TLADDLTVEAAQASLDRFARVRGDTRLRATADGRSSVAVVAXIYVRTAEQ
Mb3827|M.bovis_AF2122/97 -----TVIEDIEFEEDDAGDGARVIAR-----------------VRPRSA
Rv3798|M.tuberculosis_H37Rv -----TVIEDIEFEEDDAGDGARVIAR-----------------VRPRSA
Mflv_3476|M.gilvum_PYR-GCK -----RLLAIPGASVTDVVIGERDVEV-----------------TLRPTA
MMAR_1440|M.marinum_M -------LDELGLEATGQHLATDRAVL-----------------ACRITD
: .
MSMEG_5398|M.smegmatis_MC2_155 RVGICPECGERS----------TRSKGWVQTGPRDVVVGPDRPILRWRKR
TH_3774|M.thermoresistible__bu WVGVCPGCMVRSGVCPGCMVRSARSKGWVSTRPRDIKIGPDIPRIVWRKR
Mb3827|M.bovis_AF2122/97 VLRRCGRCGRKA---------SWYDRGAGLRQWRSLDWGTVEVFLEAEAP
Rv3798|M.tuberculosis_H37Rv VLRRCGRCGRKA---------SWYDRGAGLRQWRSLDWGTVEVFLEAEAP
Mflv_3476|M.gilvum_PYR-GCK RLLTCPCGKRQP---------SVYDRRR--RRWRHLDLGVKRLWLVNEIR
MMAR_1440|M.marinum_M DGSWCRRCGEQG-----------TVRDGVTRQLAHEPFGWRPTTLLVTIR
* : : * :
MSMEG_5398|M.smegmatis_MC2_155 KWLCPSTVCTRKVFTESVPGIPARARVTPRAKATMATAVLDEDRSVAAVA
TH_3774|M.thermoresistible__bu KWVCANMCCDRKSFTESVPSIPPRARVTVRAKREMASAVLDDDRSVKAVA
Mb3827|M.bovis_AF2122/97 RVNCP----THGPTVVAVPWARHHAGHTYAFDDTVAWLAVACSK--TAVC
Rv3798|M.tuberculosis_H37Rv RVNCP----THGPTVVAVPWARHHAGHTYAFDDTVAWLAVACSK--TAVC
Mflv_3476|M.gilvum_PYR-GCK RLNCP----DCGVITEAVPWARPGSRFTRDFEDMVLWLAQRSDR--TTVS
MMAR_1440|M.marinum_M RYRCQG--CAHVWRQDSGKAAEPRAKLSRRGLRWALEAIVCRHLSVARIA
: * : : : :.
MSMEG_5398|M.smegmatis_MC2_155 GQYRCGWHTVHDEVIATAEDALAGELAPVAVLGIDETRRGKAKWEHNPVL
TH_3774|M.thermoresistible__bu AAYGCTWNTCHDAVIATADPVLAGEPEAVSVLGIDETRRGKAKWETCSQT
Mb3827|M.bovis_AF2122/97 ELMRIAWRTVGAIVARVWADTEKRIDRFANLR-----RIGIDEISYKRHH
Rv3798|M.tuberculosis_H37Rv ELMRIAWRTVGAIVARVWADTEKRIDRFANLR-----RIGIDEISYKRHH
Mflv_3476|M.gilvum_PYR-GCK TLMRCAWESVTAIINRGVAELLD-KRRLQTLY-----RIGVDEICYRHPH
MMAR_1440|M.marinum_M EALAVSWNTANNAVLAEGRRVLIADPARFDSVAVIG--VDEHVWRHTRRG
*.: : .
MSMEG_5398|M.smegmatis_MC2_155 GRRVWVDRWDTGLVDITGDQGLLGQVNGRTSAAVIDWLAGQDPDWRAAIT
TH_3774|M.thermoresistible__bu GTRSWVDRFDTGLVDITGTGGLLVQVNGRAAKPVTDWLDQRDPGWKATIE
Mb3827|M.bovis_AF2122/97 RYLTVVVDHDS--------GRLVWAAPSHPGLVL----------------
Rv3798|M.tuberculosis_H37Rv RYLTVVVDHDS--------GRLVWAAPGHDKATLGLFFDALGAERAAQIT
Mflv_3476|M.gilvum_PYR-GCK RYLTIIGDHDT--------GTVVNIRPGRSEQSLTDFYTAQ-PDSMLKIQ
MMAR_1440|M.marinum_M DKYVIVIIDLTPVRDKTGPARLLDMVEGRSKKAFQDWLAGRPKQWRDGVE
: : :: .: .
MSMEG_5398|M.smegmatis_MC2_155 HVAIDLSPAYARVAREALPHAILIADRFHLVKKANDMVDAVRRRVTWTQR
TH_3774|M.thermoresistible__bu FVAIDMSVTYANAARQALPHAKLIVDRFHLVKRANEMVDEVRRRTTQAHR
Mb3827|M.bovis_AF2122/97 ----------------RCPGR-----------------------------
Rv3798|M.tuberculosis_H37Rv HVSADAADWIADVVTERCPDAIQCADPFHVVAWATEALDVERRRAWNDAR
Mflv_3476|M.gilvum_PYR-GCK AVSMDVSKPYIGATRSKVPEAIICFDGFHIMRWINRALDAVFSEAAAGPD
MMAR_1440|M.marinum_M VVAMDGFSGFKTATTEELPGAATVMAPFHVVRLAGNALDECRRRVQMDTC
*
MSMEG_5398|M.smegmatis_MC2_155 GRRGRKADVE-------------------WINRRRLLRGSERLTADQRAT
TH_3774|M.thermoresistible__bu LRRGRKSDPE-------------------WINRRRLLRAAERLTDEQRHK
Mb3827|M.bovis_AF2122/97 --------------------------------------------------
Rv3798|M.tuberculosis_H37Rv AIARTEPKWGRGRPGKNAAPRPGRERARRLKGARYALWKNPEDLTERQSA
Mflv_3476|M.gilvum_PYR-GCK KVHMSSAQWR---------------------TTRWALRTGENRLTDTKRE
MMAR_1440|M.marinum_M GHRGRRTDPLY--------------------ACRRTLQTGADLLTDKQKT
MSMEG_5398|M.smegmatis_MC2_155 LFAKLLSADPNQDIAAAWIAKELLRDLLSCADRGGLRYEITTALDRFYRF
TH_3774|M.thermoresistible__bu LFVKLTSADPNGDIAAAWIAKELLRDVLACTARGGLTYEIRDALYRFYTF
Mb3827|M.bovis_AF2122/97 --------------------------------------------------
Rv3798|M.tuberculosis_H37Rv KLAWIAKTDPR--LYRAYLLKESLRHVFSVKGEE-----GKQALDRWISW
Mflv_3476|M.gilvum_PYR-GCK LVNQIAKQNRR--VGRAWALKEQARDLYRYDHQPGV---ARALLKAWITA
MMAR_1440|M.marinum_M RLTALLS-------------------------------------------
MSMEG_5398|M.smegmatis_MC2_155 CAACTVPEVIRLARTIETWQAPIIAALQTGLSNARTEGYNRIVKHVGRIA
TH_3774|M.thermoresistible__bu CAACSVPEISKLARTISAWQEPMILAIQTGLSNARSEGYNRIIKHVGRIA
Mb3827|M.bovis_AF2122/97 --------------------------------------------------
Rv3798|M.tuberculosis_H37Rv AQRCRIPVFVELAARIKRHRVAIDAALDHGLSQGLIESTNTKIRLLTRIA
Mflv_3476|M.gilvum_PYR-GCK AKRCRIPAFVALGKRLAVYFDGILAAIELGISNALAESINAKIRLINARG
MMAR_1440|M.marinum_M ---CAVGFVLRLNSADPGAGFAMLLAACVAISRFACDG-------CHSVA
MSMEG_5398|M.smegmatis_MC2_155 FGFRNPENQRRRVRWACTRRSRRVTPS-RHQRHC-
TH_3774|M.thermoresistible__bu FGFRNPENQRRRVRWACTRQSRRTPPSTKQVRPC-
Mb3827|M.bovis_AF2122/97 -----------------------------------
Rv3798|M.tuberculosis_H37Rv FGFRSPQALIALAMLTLAGHRPTLPGRHNHPQISQ
Mflv_3476|M.gilvum_PYR-GCK YGHHTAETLTSMIYLCLGGLQVKLPTRT-------
MMAR_1440|M.marinum_M FGSAWTDDLLPGWW---------------------