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AIDPAAAYASAIRTPGLLPNAKLVVDHFHVTTLANDALTAVRRRVTWAFHDRRGRKIDPQWANRRRLLTA RERLSDKSFAKMRNRINAVDPRAQILSAWIAKEELRTLLSTVRTGGDPHLARHHLHRFLPGASTRRSPNC SPWPPPLTSHPRSTPSWSPASPTRASVVGEVAEMLGDIDGQCVQVEVPVPERGPAGCGGLDGLGRAGVSA TPRVCAAMTAVNVAGRCAGQQADVGPTPQHRCRGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3349c | - | - | 100% (246) | PROBABLE TRANSPOSASE |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3382c | - | 1e-145 | 100.00% (246) | transposase |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_1440 | - | 1e-08 | 35.65% (115) | ISL3 family transposase |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_5398 | - | 3e-24 | 48.06% (129) | ISMsm4, transposase |
| M. thermoresistible (build 8) | TH_2014 | - | 4e-54 | 77.69% (130) | PROBABLE TRANSPOSASE |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3349c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3382c|M.bovis_AF2122/97 --------------------------------------------------
TH_2014|M.thermoresistible__bu --------------------------------------------------
MSMEG_5398|M.smegmatis_MC2_155 MSWVFFRHPGQGTRTMVDGSSLLLDLDGVVVESVQRLEDGTRLVQVLTAP
MMAR_1440|M.marinum_M ---------MPDATFACPDLTTFCRLDELGLEATGQHLATDRAVLACRIT
Rv3349c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3382c|M.bovis_AF2122/97 --------------------------------------------------
TH_2014|M.thermoresistible__bu --------------------------------------------------
MSMEG_5398|M.smegmatis_MC2_155 QRVGICPECGERSTRSKGWVQTGPRDVVVGPDRPILRWRKRKWLCPSTVC
MMAR_1440|M.marinum_M DDGSWCRRCGEQGTVRDG-VTRQLAHEPFGWRPTTLLVTIRRYRCQG--C
Rv3349c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3382c|M.bovis_AF2122/97 --------------------------------------------------
TH_2014|M.thermoresistible__bu --------------------------------------------------
MSMEG_5398|M.smegmatis_MC2_155 TRKVFTESVPGIPARARVTPRAKATMATAVLDEDRSVAAVAGQYRCGWHT
MMAR_1440|M.marinum_M AHVWRQDSGKAAEPRAKLSRRGLRWALEAIVCRHLSVARIAEALAVSWNT
Rv3349c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3382c|M.bovis_AF2122/97 --------------------------------------------------
TH_2014|M.thermoresistible__bu --------------------------------------------VRIDPW
MSMEG_5398|M.smegmatis_MC2_155 VHDEVIATAEDALAGELAPVAVLGIDETRRGKAKWEHNPVLGRRVWVDRW
MMAR_1440|M.marinum_M ANNAVLAEGRRVLIADPARFDSVAVIG--VDEHVWRHTRRGDKYVIVIID
Rv3349c|M.tuberculosis_H37Rv ------------------------------------------MAIDPAAA
Mb3382c|M.bovis_AF2122/97 ------------------------------------------MAIDPAAA
TH_2014|M.thermoresistible__bu DTGFVDLSGNQGLLGQREGRTSAAVIDWLNERTPQFREAVQFVAIDPAAV
MSMEG_5398|M.smegmatis_MC2_155 DTGLVDITGDQGLLGQVNGRTSAAVIDWLAGQDPDWRAAITHVAIDLSPA
MMAR_1440|M.marinum_M LTPVRDKTGPARLLDMVEGRSKKAFQDWLAGRPKQWRDGVEVVAMDGFSG
:*:* .
Rv3349c|M.tuberculosis_H37Rv YASAIRTPGLLPNAKLVVDHFHVTTLANDALTAVRRRVTWAFHDRRGRKI
Mb3382c|M.bovis_AF2122/97 YASAIRTPGLLPNAKLVVDHFHVTTLANDALTAVRRRVTWAFHDRRGRKI
TH_2014|M.thermoresistible__bu YAAAIRTPGLLPNATIVVDHFHLVKLGNEALTKVRRRVTWDLRDRRGRKA
MSMEG_5398|M.smegmatis_MC2_155 YARVAREA--LPHAILIADRFHLVKKANDMVDAVRRRVTWTQRGRRGRKA
MMAR_1440|M.marinum_M FKTATTEE--LPGAATVMAPFHVVRLAGNALDECRRRVQMDTCGHRGRRT
: . ** * : **:. ..: : **** .:***:
Rv3349c|M.tuberculosis_H37Rv DPQWANRRRLLTARERLSDKSFAKMRNRINAVDPRAQILSAWIAKEELRT
Mb3382c|M.bovis_AF2122/97 DPQWANRRRLLTARERLSDKSFAKMRNRINAVDPRAQILSAWIAKEELRT
TH_2014|M.thermoresistible__bu DPEWANRRRLLRGRERLSDKAFAKMWNAIVDADDSGQILSAWIAKEELRT
MSMEG_5398|M.smegmatis_MC2_155 DVEWINRRRLLRGSERLTADQRATLFAKLLSADPNQDIAAAWIAKELLRD
MMAR_1440|M.marinum_M DPLYACRRTLQTGADLLTDKQKTRLTALLSCAVG-------------FVL
* : ** * . : *: . : : : . :
Rv3349c|M.tuberculosis_H37Rv LLSTVRTGGDPHLARHHLHRFLPGASTRRSPNCSPWPPPLTSHPRSTPSW
Mb3382c|M.bovis_AF2122/97 LLSTVRTGGDPHLARHHLHRFLPGASTRRSPNCSPWPPPLTSHPRSTPSW
TH_2014|M.thermoresistible__bu LLSTVRLGGDPHLTRHRLHRFLSWCIDSKIP-------ELLALASTVDTW
MSMEG_5398|M.smegmatis_MC2_155 LLSCADRGGLRYEITTALDRFYRFCAACTVP-------EVIRLARTIETW
MMAR_1440|M.marinum_M RLNSADPGAGFAMLLAACVAISRFACDGCHS-------------------
*. . *. : . .
Rv3349c|M.tuberculosis_H37Rv SPASPTRASVVGEVAEMLGDIDGQCVQVEVPVPERGPAGCGGLDGLGRAG
Mb3382c|M.bovis_AF2122/97 SPASPTRASVVGEVAEMLGDIDGQCVQVEVPVPERGPAGCGGLDGLGRAG
TH_2014|M.thermoresistible__bu WPEIN-AFLVTGITNARTEGYNRLVKQVKR-------AACG---------
MSMEG_5398|M.smegmatis_MC2_155 Q-APIIAALQTGLSNARTEGYNRIVKHVGR-------IAFG---------
MMAR_1440|M.marinum_M ------VAFGSAWTDDLLPGWW----------------------------
. .
Rv3349c|M.tuberculosis_H37Rv VSATPRVCAAMTAVNVAGRCAGQQADVGPTPQHRCRGR
Mb3382c|M.bovis_AF2122/97 VSATPRVCAAMTAVNVAGRCAGQQADVGPTPQHRCRGR
TH_2014|M.thermoresistible__bu -FRNP----TNSARRIRFHCTRKQRAATRT----CS--
MSMEG_5398|M.smegmatis_MC2_155 -FRNP----ENQRRRVRWACTRRSRRVTPSRHQRHC--
MMAR_1440|M.marinum_M --------------------------------------