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TTTAPKPSDTEREPGQLVEMSWDPITRIVGSLGIYTKIDFENREVVECHSTSSIFRGYSLFMKGKDPRDA HFITSRICGICGDNHATCSCYAQNMAYGVQPPHVAEWIVNLGEAAEYMFDHNIFQENLVGVDFCEKMVSE TNPSVLAKAENTEAPHAGMHGYRTIADIMRALNPFTGEFYREALQVSRWTREMFCLMEGRHVHPSTLYPG GVGTVATIQLMTDYMTRLMRYVEFMKKVVPMHDDLFDFFYEALPGYEQVGLRRTLLGCWGSFQDPEHCNF SYRDMEAWGRKMFVTPGVVVDGKLVTTSLVDINLGIRILLGHSYYDDWEDQEMFVKTDPLGNPVDRRHPW NQHTNPKPQKRDFDENYSWVMSPRWFDGKDHLALDTGGGPLARLWATALAGLVDIGYVRSTGNSVQINLP KTALKGPVEFEWKIPAKGSNTIERNRARTYFQAYAAACALHFAEKALTEIRAGRTKTWEKFEVPDEGIGC GFTEAVRGVLSHHMVIRDGKIANYHPYPPTPWNANPRDSYGTPGPYEDAVQGQPIFEENDREHFKGIDIM RTVRSFDPCLPCGVHMYLGGGKTLDLLHTPTQSATGD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2719 | - | - | 100% (598) | hydrogen:quinone oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_2263 | hybC | 4e-32 | 24.59% (606) | hydrogenase-2, large subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_1869 | hyaB | 0.0 | 90.48% (599) | nickel/iron-hydrogenase I large subunit, HyaB |
| M. avium 104 | MAV_2682 | - | 0.0 | 90.64% (598) | hydrogen:quinone oxidoreductase |
| M. thermoresistible (build 8) | TH_1953 | - | 0.0 | 91.26% (595) | hydrogen:quinone oxidoreductase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2366 | - | 1e-30 | 25.00% (596) | hydrogen:quinone oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2719|M.smegmatis_MC2_155 ----MTTTAPKPSDTEREPGQLVEMSWDPITRIVGSLGIYTKIDFENREV
TH_1953|M.thermoresistible__bu MTDMIRGTRSESAHAKREPGQLVEMAWDPITRIVGSLGIYTKIDFDNREV
MAV_2682|M.avium_104 ----MTTIIPKPSHAKRGPGQLVEMAWDPITRIVGSLGIYTKIDFDNREV
MMAR_1869|M.marinum_M ----MTTIVPEPTTAKREPGQLVEMAWDPITRIVGSLGIYTKIDFENREV
Mvan_2366|M.vanbaalenii_PYR-1 ------------------MASKLDLFVSPLGRVEGDLDVR--VTIEDGVV
.. ::: .*: *: *.*.: : ::: *
MSMEG_2719|M.smegmatis_MC2_155 VECHSTSSIFRGYSLFMKGKDPRDAHFITSRICGICGDNHATCSCYAQNM
TH_1953|M.thermoresistible__bu VECFSTSSIFRGYSLFMKGKDPRDAHFITSRICGICGDNHATCSCYTQNM
MAV_2682|M.avium_104 VECHSTSSIFRGYSIFMKGKDPRDAHFITSRICGICGDNHCTCSVYTQNM
MMAR_1869|M.marinum_M VECHSTSSIFRGYSIFMKGKDPRDAHFITSRICGICGDNHATCSCYAQNM
Mvan_2366|M.vanbaalenii_PYR-1 TSAWTEAAMFRGFEIILQGKDPQSGLVVCPRICGICGGSHLYKSAYALDT
... : :::***:.::::****:.. .: .*******..* * *: :
MSMEG_2719|M.smegmatis_MC2_155 AYGVQPPHVAEWIVNLGEAAEYMFDHNIFQENLVGVDFCEKMVSETNPSV
TH_1953|M.thermoresistible__bu AYGVQPPHLAEWLVNLGEAAEYMFDHNIFQENLVGVDYCEKMVSETNPGV
MAV_2682|M.avium_104 AYGVQPPHLAEWITNLGEAAEYMFDHNIFQENLVGVDYCEKMVKETNPGV
MMAR_1869|M.marinum_M AYGVRPPHLGEWIVNLGEAAEYMFDHNIFQENLVGVDFCEKMVSETNPGV
Mvan_2366|M.vanbaalenii_PYR-1 AWRTHMPHNATLVRNICQACETLQSIPRYFYALFAIDLTNKNYAKS----
*: .: ** . : *: :*.* : . : *..:* :* ::
MSMEG_2719|M.smegmatis_MC2_155 LAKAENTEAPHAGMHGYRTIADIMRALNPFTGEFYREALQVSRWTREMFC
TH_1953|M.thermoresistible__bu LAKAENTAAPHADMHGYRTVADIMRALNPFTGEFYREALQVSRMTREMFC
MAV_2682|M.avium_104 LAKAENTAAPHAGAHGYKTIADIMRSLNPFSGEFYREALQVSRMTREMFC
MMAR_1869|M.marinum_M LAKAEKTEAPHADAHGYKTIADIMRSLNPFSGEFYREALQVSRWTREMFC
Mvan_2366|M.vanbaalenii_PYR-1 -----------------ALYDEAVRRFAPYVGTSYQPGVVLSAKPVEVYA
: :* : *: * *: .: :* . *::.
MSMEG_2719|M.smegmatis_MC2_155 LMEGRHVHPSTLYPGGVGTVATIQLMTDYMTRLMRYVEFMKKVVPMHDDL
TH_1953|M.thermoresistible__bu LMEGRHVHPSTLYPGGIGVSATVQLMTDYMSRLMRYVEFMKKVVPMHDDL
MAV_2682|M.avium_104 LMEGRHVHPSTLYPGGVGTVATIQLMTDYMSRLMRYVEFMKKVVPMHDDL
MMAR_1869|M.marinum_M LMEGRHVHPSTLYPGGVGTVATIQLMTDYMTRLMRYVEFMKKVVPLHDDL
Mvan_2366|M.vanbaalenii_PYR-1 IYGGQWPHSSFMVPGGVMCAPTLSDVTRSIAILEHWNDAWLEGQWLG-CS
: *: *.* : ***: .*:. :* :: * :: : : :
MSMEG_2719|M.smegmatis_MC2_155 FDFFYEALPGYEQVGLRRTLLGCWGSFQDPEHCNFSYRDMEAWGR--KMF
TH_1953|M.thermoresistible__bu FDFFYEALPGYDQVGLRRTLLGCWGSFQDPEVCNFRYADMEDWGR--KMF
MAV_2682|M.avium_104 FDFFYEALPGYEKSGLRRTLLACWGSYQDPEHCNFSYKDMEKWGR--KMF
MMAR_1869|M.marinum_M FDFFYDALPGYEKVGLRRTLLGCWGSFQDPEVCNFEYKDMERWGN--AMF
Mvan_2366|M.vanbaalenii_PYR-1 VDRWLENKTWNDVLAWVDENEAQYNSDCGFFIRYCLDVGLDKYGQGVGNY
.* : : . : . . :.* . .:: :*. :
MSMEG_2719|M.smegmatis_MC2_155 VTPGVVVDGKLVTTSLVDIN----LGIRILLGHSYYDDWEDQEMFVKTDP
TH_1953|M.thermoresistible__bu VTPGIVVDGKLITTSLVDIN----LGIRILLGHSYYDDWEDQEMFVETDP
MAV_2682|M.avium_104 VTPGIVVDGKLVTTSLVDIN----LGIRILLGSSYYDDWTDQEMFVKTDP
MMAR_1869|M.marinum_M VTPGVVVDGKLVTHSLVDIN----LGIRILLGSSYYDDWTDQEMFVKTDP
Mvan_2366|M.vanbaalenii_PYR-1 LATGTYFEPSLYENPTIDGRNAALIGRSGVYADGRYFEFDQANVLEDVTH
::.* .: .* . :* . :* : . . * :: : ::: ..
MSMEG_2719|M.smegmatis_MC2_155 LGNPVDR-RHPWNQHTNPKPQKRDFDEN-YSWVMSPRWFDGKDHLALDTG
TH_1953|M.thermoresistible__bu LGNPVDR-RHPWNQHTNPRPQKRDFDEN-YSWVMSPRWFDGTDHLALDTG
MAV_2682|M.avium_104 LGNPVDR-RHPWNQHTNPHPQKRDMEDK-YSWVMSPRWFDGKDHLALDTG
MMAR_1869|M.marinum_M LGNKVDR-RHPWNQHTNPHPQKREMDGGKYSWVMSPRWFDGKDHLALDTG
Mvan_2366|M.vanbaalenii_PYR-1 SFYQGDRPLHPFDGETIPIDPEQGRKQGKYSWAKSPRYAVG-DLGNIPLE
** **:: .* * :: . ***. ***: * * :
MSMEG_2719|M.smegmatis_MC2_155 GGPLARLWATALAGLVDIGYVRSTGNSVQINLPKTALKGPVEFEWKIPAK
TH_1953|M.thermoresistible__bu GGPLARLWSTALANLVDIGYVRSTGHSVQINLPKTALKGPVELEWKIPRH
MAV_2682|M.avium_104 GGPLARLWSTALAGLVDIGYVKATGRSVQINLPKTALKGPVELEWKIPEH
MMAR_1869|M.marinum_M GGPLARLWATALAGLVDIGYVKATGNSVKINLPKTALKGPVEFEWKVPKH
Mvan_2366|M.vanbaalenii_PYR-1 AGPLAR-------------RMAAAGPDAAAHQDNDPLFG----------D
.***** : ::* .. : : .* * .
MSMEG_2719|M.smegmatis_MC2_155 GSNTIERNRARTYFQAYAAACALHFAEKALTEIRAGRTKTWEKFEVPDEG
TH_1953|M.thermoresistible__bu GSNTIERNRARTYFQAYSAACALHFAEKALTEIRAGRTKTWEPFEVPDEG
MAV_2682|M.avium_104 GSNTIERNRARTYFQAYSAAAALHFAEKALVEIRAGRTKTWEKFEVPDEG
MMAR_1869|M.marinum_M GSNTIERDRARTYFQAYAAACALHFAEKALAEIRAGRTKTWEKFEVPDEG
Mvan_2366|M.vanbaalenii_PYR-1 IYNTIGPSVMVRQLARMHEAPKYYKWTRQWLDALELKESFYTKPTEYAEG
*** . : * : : : : . : **
MSMEG_2719|M.smegmatis_MC2_155 IGCGFTEAVRGVLSHHMVIRDGKIANYHPYPPTPWNANPRDSYGTPGPYE
TH_1953|M.thermoresistible__bu IGCGFTEAVRGVLSHHMVIRDGKIANYHPYPPTPWNANPRDVYGTPGPYE
MAV_2682|M.avium_104 IGCGFTEAVRGVLSHHMVIRDGKIANYHPYPPTPWNANPRDVYGTPGPYE
MMAR_1869|M.marinum_M IGCGFTEAVRGVLSHHLVIRNGKIANYHPYPPTPWNANPRDSFGTPGPYE
Mvan_2366|M.vanbaalenii_PYR-1 KGFGSTEAARGALSDWIVIEDSKIKNYQVVTPTAWNIGPRDGSEVLGPIE
* * ***.**.**. :**.:.** **: .**.** .*** . ** *
MSMEG_2719|M.smegmatis_MC2_155 DAVQGQPIFEENDREHFKGIDIMRTVRSFDPCLPCGVHMYLGG-GKTLDL
TH_1953|M.thermoresistible__bu DAVQGQPIFEENDREHFKGIDIMRTVRSFDPCLPCGVHMYLGK-GRKLEL
MAV_2682|M.avium_104 DAVQGQPIFEENDRDNFKGIDIMRTVRSFDPCLPCGVHMYLGK-GKTLDR
MMAR_1869|M.marinum_M DAVQGQPIFEENDRENFKGIDVMRTVRSFDPCLPCGVHMYLGK-GKTLER
Mvan_2366|M.vanbaalenii_PYR-1 RALVGSPIVDAEDP-----VELGHVARSFDSCLVCTVHAYDGKTGRELSK
*: *.**.: :* ::: :..****.** * ** * * *: *.
MSMEG_2719|M.smegmatis_MC2_155 LHTPTQSATGD
TH_1953|M.thermoresistible__bu LHSPTQTITGE
MAV_2682|M.avium_104 LHSPTQTATGE
MMAR_1869|M.marinum_M LHTPTQSPVGE
Mvan_2366|M.vanbaalenii_PYR-1 FVINGMV----
: