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M. marinum M MMAR_1869 (hyaB)

annotation: nickel/iron-hydrogenase I large subunit, HyaB
coordinates: 2274926 - 2276725
length: 599

TTIVPEPTTAKREPGQLVEMAWDPITRIVGSLGIYTKIDFENREVVECHSTSSIFRGYSIFMKGKDPRDA
HFITSRICGICGDNHATCSCYAQNMAYGVRPPHLGEWIVNLGEAAEYMFDHNIFQENLVGVDFCEKMVSE
TNPGVLAKAEKTEAPHADAHGYKTIADIMRSLNPFSGEFYREALQVSRWTREMFCLMEGRHVHPSTLYPG
GVGTVATIQLMTDYMTRLMRYVEFMKKVVPLHDDLFDFFYDALPGYEKVGLRRTLLGCWGSFQDPEVCNF
EYKDMERWGNAMFVTPGVVVDGKLVTHSLVDINLGIRILLGSSYYDDWTDQEMFVKTDPLGNKVDRRHPW
NQHTNPHPQKREMDGGKYSWVMSPRWFDGKDHLALDTGGGPLARLWATALAGLVDIGYVKATGNSVKINL
PKTALKGPVEFEWKVPKHGSNTIERDRARTYFQAYAAACALHFAEKALAEIRAGRTKTWEKFEVPDEGIG
CGFTEAVRGVLSHHLVIRNGKIANYHPYPPTPWNANPRDSFGTPGPYEDAVQGQPIFEENDRENFKGIDV
MRTVRSFDPCLPCGVHMYLGKGKTLERLHTPTQSPVGE*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_1869hyaB-100% (599)nickel/iron-hydrogenase I large subunit, HyaB

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCK-----
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. avium 104MAV_2682-0.090.48% (599) hydrogen:quinone oxidoreductase
M. smegmatis MC2 155MSMEG_2719-0.090.48% (599) hydrogen:quinone oxidoreductase
M. thermoresistible (build 8)TH_1953-0.087.69% (593) hydrogen:quinone oxidoreductase
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_2366-6e-3425.63% (593) hydrogen:quinone oxidoreductase

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_2719|M.smegmatis_MC2_155      ----MTTTAPKPSDTEREPGQLVEMSWDPITRIVGSLGIYTKIDFENREV
TH_1953|M.thermoresistible__bu      MTDMIRGTRSESAHAKREPGQLVEMAWDPITRIVGSLGIYTKIDFDNREV
MAV_2682|M.avium_104                ----MTTIIPKPSHAKRGPGQLVEMAWDPITRIVGSLGIYTKIDFDNREV
MMAR_1869|M.marinum_M               ----MTTIVPEPTTAKREPGQLVEMAWDPITRIVGSLGIYTKIDFENREV
Mvan_2366|M.vanbaalenii_PYR-1       ------------------MASKLDLFVSPLGRVEGDLDVR--VTIEDGVV
                                                       .. :::  .*: *: *.*.:   : :::  *

MSMEG_2719|M.smegmatis_MC2_155      VECHSTSSIFRGYSLFMKGKDPRDAHFITSRICGICGDNHATCSCYAQNM
TH_1953|M.thermoresistible__bu      VECFSTSSIFRGYSLFMKGKDPRDAHFITSRICGICGDNHATCSCYTQNM
MAV_2682|M.avium_104                VECHSTSSIFRGYSIFMKGKDPRDAHFITSRICGICGDNHCTCSVYTQNM
MMAR_1869|M.marinum_M               VECHSTSSIFRGYSIFMKGKDPRDAHFITSRICGICGDNHATCSCYAQNM
Mvan_2366|M.vanbaalenii_PYR-1       TSAWTEAAMFRGFEIILQGKDPQSGLVVCPRICGICGGSHLYKSAYALDT
                                    ... : :::***:.::::****:.. .: .*******..*   * *: : 

MSMEG_2719|M.smegmatis_MC2_155      AYGVQPPHVAEWIVNLGEAAEYMFDHNIFQENLVGVDFCEKMVSETNPSV
TH_1953|M.thermoresistible__bu      AYGVQPPHLAEWLVNLGEAAEYMFDHNIFQENLVGVDYCEKMVSETNPGV
MAV_2682|M.avium_104                AYGVQPPHLAEWITNLGEAAEYMFDHNIFQENLVGVDYCEKMVKETNPGV
MMAR_1869|M.marinum_M               AYGVRPPHLGEWIVNLGEAAEYMFDHNIFQENLVGVDFCEKMVSETNPGV
Mvan_2366|M.vanbaalenii_PYR-1       AWRTHMPHNATLVRNICQACETLQSIPRYFYALFAIDLTNKNYAKS----
                                    *: .: ** .  : *: :*.* : .   :   *..:*  :*   ::    

MSMEG_2719|M.smegmatis_MC2_155      LAKAENTEAPHAGMHGYRTIADIMRALNPFTGEFYREALQVSRWTREMFC
TH_1953|M.thermoresistible__bu      LAKAENTAAPHADMHGYRTVADIMRALNPFTGEFYREALQVSRMTREMFC
MAV_2682|M.avium_104                LAKAENTAAPHAGAHGYKTIADIMRSLNPFSGEFYREALQVSRMTREMFC
MMAR_1869|M.marinum_M               LAKAEKTEAPHADAHGYKTIADIMRSLNPFSGEFYREALQVSRWTREMFC
Mvan_2366|M.vanbaalenii_PYR-1       -----------------ALYDEAVRRFAPYVGTSYQPGVVLSAKPVEVYA
                                                         : :* : *: *  *: .: :*  . *::.

MSMEG_2719|M.smegmatis_MC2_155      LMEGRHVHPSTLYPGGVGTVATIQLMTDYMTRLMRYVEFMKKVVPMHDDL
TH_1953|M.thermoresistible__bu      LMEGRHVHPSTLYPGGIGVSATVQLMTDYMSRLMRYVEFMKKVVPMHDDL
MAV_2682|M.avium_104                LMEGRHVHPSTLYPGGVGTVATIQLMTDYMSRLMRYVEFMKKVVPMHDDL
MMAR_1869|M.marinum_M               LMEGRHVHPSTLYPGGVGTVATIQLMTDYMTRLMRYVEFMKKVVPLHDDL
Mvan_2366|M.vanbaalenii_PYR-1       IYGGQWPHSSFMVPGGVMCAPTLSDVTRSIAILEHWNDAWLEGQWLG-CS
                                    :  *:  *.* : ***:   .*:. :*  :: * :: :   :   :    

MSMEG_2719|M.smegmatis_MC2_155      FDFFYEALPGYEQVGLRRTLLGCWGSFQDPEHCNFSYRDMEAWGR--KMF
TH_1953|M.thermoresistible__bu      FDFFYEALPGYDQVGLRRTLLGCWGSFQDPEVCNFRYADMEDWGR--KMF
MAV_2682|M.avium_104                FDFFYEALPGYEKSGLRRTLLACWGSYQDPEHCNFSYKDMEKWGR--KMF
MMAR_1869|M.marinum_M               FDFFYDALPGYEKVGLRRTLLGCWGSFQDPEVCNFEYKDMERWGN--AMF
Mvan_2366|M.vanbaalenii_PYR-1       VDRWLENKTWNDVLAWVDENEAQYNSDCGFFIRYCLDVGLDKYGQGVGNY
                                    .* : :  .  :  .      . :.*  .         .:: :*.    :

MSMEG_2719|M.smegmatis_MC2_155      VTPGVVVDGKLVTTSLVDIN----LGIRILLGHSYYDDWEDQEMFVKTDP
TH_1953|M.thermoresistible__bu      VTPGIVVDGKLITTSLVDIN----LGIRILLGHSYYDDWEDQEMFVETDP
MAV_2682|M.avium_104                VTPGIVVDGKLVTTSLVDIN----LGIRILLGSSYYDDWTDQEMFVKTDP
MMAR_1869|M.marinum_M               VTPGVVVDGKLVTHSLVDIN----LGIRILLGSSYYDDWTDQEMFVKTDP
Mvan_2366|M.vanbaalenii_PYR-1       LATGTYFEPSLYENPTIDGRNAALIGRSGVYADGRYFEFDQANVLEDVTH
                                    ::.*  .: .*   . :* .    :*   : . . * :: : ::: ..  

MSMEG_2719|M.smegmatis_MC2_155      LGNPVDR-RHPWNQHTNPKPQKRDFDEN-YSWVMSPRWFDGKDHLALDTG
TH_1953|M.thermoresistible__bu      LGNPVDR-RHPWNQHTNPRPQKRDFDEN-YSWVMSPRWFDGTDHLALDTG
MAV_2682|M.avium_104                LGNPVDR-RHPWNQHTNPHPQKRDMEDK-YSWVMSPRWFDGKDHLALDTG
MMAR_1869|M.marinum_M               LGNKVDR-RHPWNQHTNPHPQKREMDGGKYSWVMSPRWFDGKDHLALDTG
Mvan_2366|M.vanbaalenii_PYR-1       SFYQGDRPLHPFDGETIPIDPEQGRKQGKYSWAKSPRYAVG-DLGNIPLE
                                         **  **:: .* *   ::  .   ***. ***:  * *   :   

MSMEG_2719|M.smegmatis_MC2_155      GGPLARLWATALAGLVDIGYVRSTGNSVQINLPKTALKGPVEFEWKIPAK
TH_1953|M.thermoresistible__bu      GGPLARLWSTALANLVDIGYVRSTGHSVQINLPKTALKGPVELEWKIPRH
MAV_2682|M.avium_104                GGPLARLWSTALAGLVDIGYVKATGRSVQINLPKTALKGPVELEWKIPEH
MMAR_1869|M.marinum_M               GGPLARLWATALAGLVDIGYVKATGNSVKINLPKTALKGPVEFEWKVPKH
Mvan_2366|M.vanbaalenii_PYR-1       AGPLAR-------------RMAAAGPDAAAHQDNDPLFG----------D
                                    .*****              : ::* ..  :  : .* *          .

MSMEG_2719|M.smegmatis_MC2_155      GSNTIERNRARTYFQAYAAACALHFAEKALTEIRAGRTKTWEKFEVPDEG
TH_1953|M.thermoresistible__bu      GSNTIERNRARTYFQAYSAACALHFAEKALTEIRAGRTKTWEPFEVPDEG
MAV_2682|M.avium_104                GSNTIERNRARTYFQAYSAAAALHFAEKALVEIRAGRTKTWEKFEVPDEG
MMAR_1869|M.marinum_M               GSNTIERDRARTYFQAYAAACALHFAEKALAEIRAGRTKTWEKFEVPDEG
Mvan_2366|M.vanbaalenii_PYR-1       IYNTIGPSVMVRQLARMHEAPKYYKWTRQWLDALELKESFYTKPTEYAEG
                                      ***  .     :     *   :   :   :    : . :       **

MSMEG_2719|M.smegmatis_MC2_155      IGCGFTEAVRGVLSHHMVIRDGKIANYHPYPPTPWNANPRDSYGTPGPYE
TH_1953|M.thermoresistible__bu      IGCGFTEAVRGVLSHHMVIRDGKIANYHPYPPTPWNANPRDVYGTPGPYE
MAV_2682|M.avium_104                IGCGFTEAVRGVLSHHMVIRDGKIANYHPYPPTPWNANPRDVYGTPGPYE
MMAR_1869|M.marinum_M               IGCGFTEAVRGVLSHHLVIRNGKIANYHPYPPTPWNANPRDSFGTPGPYE
Mvan_2366|M.vanbaalenii_PYR-1       KGFGSTEAARGALSDWIVIEDSKIKNYQVVTPTAWNIGPRDGSEVLGPIE
                                     * * ***.**.**. :**.:.** **:  .**.** .***   . ** *

MSMEG_2719|M.smegmatis_MC2_155      DAVQGQPIFEENDREHFKGIDIMRTVRSFDPCLPCGVHMYLGG-GKTLDL
TH_1953|M.thermoresistible__bu      DAVQGQPIFEENDREHFKGIDIMRTVRSFDPCLPCGVHMYLGK-GRKLEL
MAV_2682|M.avium_104                DAVQGQPIFEENDRDNFKGIDIMRTVRSFDPCLPCGVHMYLGK-GKTLDR
MMAR_1869|M.marinum_M               DAVQGQPIFEENDRENFKGIDVMRTVRSFDPCLPCGVHMYLGK-GKTLER
Mvan_2366|M.vanbaalenii_PYR-1       RALVGSPIVDAEDP-----VELGHVARSFDSCLVCTVHAYDGKTGRELSK
                                     *: *.**.: :*      ::: :..****.** * ** * *  *: *. 

MSMEG_2719|M.smegmatis_MC2_155      LHTPTQSATGD
TH_1953|M.thermoresistible__bu      LHSPTQTITGE
MAV_2682|M.avium_104                LHSPTQTATGE
MMAR_1869|M.marinum_M               LHTPTQSPVGE
Mvan_2366|M.vanbaalenii_PYR-1       FVINGMV----
                                    :