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PTIKDTITTPDGTCPVTVATPEGSGPWPGVVLFPDAGGLRPTMEEMAAKLAGFGYVVLVPDVYYRIPNWG PINLNTVFSDQDERKKLFEMMGTLTPEVIASDAEAFFDYLAARPDVTGEKFGTTGYCMGGRASLIVATRV PDRVAAALSFHGGRIAVEDDPDSPHLLADKIQAVVYVAGAENDASFTEDDAKRLEDALSGASVEHTIEFY PAGHGFAVPDHLSVYDEAAAQRHWENTERVFGAALASA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2669 | - | - | 100% (249) | hydrolase |
| M. smegmatis MC2 155 | MSMEG_2444 | - | 3e-17 | 30.25% (238) | dienelactone hydrolase family protein |
| M. smegmatis MC2 155 | MSMEG_3558 | - | 1e-08 | 26.53% (245) | carboxymethylenebutenolidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2787 | - | 2e-85 | 60.16% (246) | hypothetical protein Mb2787 |
| M. gilvum PYR-GCK | Mflv_4008 | - | 1e-88 | 62.20% (246) | dienelactone hydrolase |
| M. tuberculosis H37Rv | Rv2765 | - | 2e-85 | 60.16% (246) | hypothetical protein Rv2765 |
| M. leprae Br4923 | MLBr_01444 | - | 2e-15 | 28.85% (253) | putative dienelactone hydrolase |
| M. abscessus ATCC 19977 | MAB_3183c | - | 3e-69 | 55.65% (239) | dienelactone hydrolase |
| M. marinum M | MMAR_1955 | - | 6e-90 | 62.75% (247) | alanine rich hydrolase |
| M. avium 104 | MAV_3654 | - | 1e-91 | 63.82% (246) | hydrolase |
| M. thermoresistible (build 8) | TH_0693 | - | 9e-79 | 60.17% (231) | PROBABLE ALANINE RICH HYDROLASE |
| M. ulcerans Agy99 | MUL_2177 | - | 9e-90 | 62.75% (247) | alanine rich hydrolase |
| M. vanbaalenii PYR-1 | Mvan_2379 | - | 5e-89 | 61.79% (246) | dienelactone hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2787|M.bovis_AF2122/97 MPKTTDTAATPDGTCAVRLFTPDGPGRWPGVVMFPDAGGVRDTFDRMAAK
Rv2765|M.tuberculosis_H37Rv MPKTTDTAATPDGTCAVRLFTPDGPGRWPGVVMFPDAGGVRDTFDRMAAK
MMAR_1955|M.marinum_M MPIISDSVSTPDGTCPVRLFTPAGPGPWPGVIMFPDAGGVRETFEQMAAT
MUL_2177|M.ulcerans_Agy99 MPIISDSVSTPDGTCPVRLFTPAGPGPWPGVIMFPDAGGVRETFEQMAAT
MAV_3654|M.avium_104 MPKITDSISTADGTCPVRLFFPDGSGPWPGVVMYPDAGGVRDTFDQMAAE
TH_0693|M.thermoresistible__bu ----------------VTLHTPDGAGPWPGVVLFVDAGGTRDLMREMADR
Mflv_4008|M.gilvum_PYR-GCK MPTITDTVTTTDGSCPVTLHTPDGDGPWRGIVMYPDAGGVRPTFRTMADQ
Mvan_2379|M.vanbaalenii_PYR-1 MPRITDTVTTADGDCPVSLHTPDGGGPWRGIVMYPDAGGARPTFRAMADK
MSMEG_2669|M.smegmatis_MC2_155 MPTIKDTITTPDGTCPVTVATPEGSGPWPGVVLFPDAGGLRPTMEEMAAK
MAB_3183c|M.abscessus_ATCC_199 MQRRDAQILTPDGLCSATLHLPDQPG--PAVVLYPDAGGARDVMRAMGDR
MLBr_01444|M.leprae_Br4923 --MTKIQIDAPDGPIDALLSVPPGPEPWPGVVVIHDAIGYEPDKESTNNH
. : * .::: ** * .
Mb2787|M.bovis_AF2122/97 LAGFGYVVLLPDVYYREGDWAPFDMKTAFGDPQERARIMFMIGTLTPDRV
Rv2765|M.tuberculosis_H37Rv LAGFGYVVLLPDVYYREGDWAPFDMKTAFGDPQERARIMFMIGTLTPDRV
MMAR_1955|M.marinum_M LAGHGYVVLLPDVYYREGDWTPFAMETVFGDADERARLMFMLGTLTPDRV
MUL_2177|M.ulcerans_Agy99 LAGHGYVVLLPDVYYREGDWTPFAMETVFGDADERARLMFMLGTLTPDRV
MAV_3654|M.avium_104 LAGFGYAVLLPDVYYRSGEWAPFDMATVFADQQERNRLFAMIGSVTPDRM
TH_0693|M.thermoresistible__bu LAGYGYAVLVPDVYYRHGRWEPFDMRTVFGDPSERARLYRMIRSITPDMM
Mflv_4008|M.gilvum_PYR-GCK LAGHGYAVLLPDVYYREGDWAPFTMSTVFGDAAERRRLFGMISKVTPERM
Mvan_2379|M.vanbaalenii_PYR-1 LAGYGYAVLVPDVYYREGDWAPFTIATAFDDDVERRRLFSFMAKVTPEVM
MSMEG_2669|M.smegmatis_MC2_155 LAGFGYVVLVPDVYYRIPNWGPINLNTVFSDQDERKKLFEMMGTLTPEVI
MAB_3183c|M.abscessus_ATCC_199 LASWGYVVLVPDVYYREGNWQPFNMATAFGDTQERGRLFATMGTLTPDRI
MLBr_01444|M.leprae_Br4923 IAMAGYVAITPNLYSR-GSRARCITRVMRELLTKRGRAFDDILATR----
:* **..: *::* * . :* : :
Mb2787|M.bovis_AF2122/97 TRDADALLNYLASRPEVIGDRFGVCGYCMGGRMSVVVAGRLPDRVAAAAA
Rv2765|M.tuberculosis_H37Rv TRDADALLNYLASRPEVIGDRFGVCGYCMGGRMSVVVAGRLPDRVAAAAA
MMAR_1955|M.marinum_M TRDAGAYFDYLATRPQVSGERFGVCGYCMGGRISVLLAGRQPDRVAAAAS
MUL_2177|M.ulcerans_Agy99 TRDAGAYFDYLATRPQVSGERFGVCGYCMGGRISVLLAGRQPDRVAAAAS
MAV_3654|M.avium_104 ATDAAAFFDYLAARPEVSGDRFGVCGYCMGGRTSLIVAGRLPDRVAAAAS
TH_0693|M.thermoresistible__bu ETDARAFFDFLQSRPEVKGDRFGVFGYCMGGRMSVTVAGRVPDRVAAAAS
Mflv_4008|M.gilvum_PYR-GCK ESDAVAFFDYLADRPEVSGETFGTTGYCMGGRTSLVVAGRVPQRVAAAMS
Mvan_2379|M.vanbaalenii_PYR-1 AADATAFFDYLAGRPEVRGDTFGTTGYCMGGRTSLVLAGRLPDRVSAAMS
MSMEG_2669|M.smegmatis_MC2_155 ASDAEAFFDYLAARPDVTGEKFGTTGYCMGGRASLIVATRVPDRVAAALS
MAB_3183c|M.abscessus_ATCC_199 DADAGSFLDFLADQPEVTGELVGLTGYCMGGRISLRVAATHASRVGAVAS
MLBr_01444|M.leprae_Br4923 --------DYLLAMPKCSG-RVGIAGFCMGGRFALVMS---PKGFDASAP
::* *. * .* *:***** :: :: .. . * .
Mb2787|M.bovis_AF2122/97 FHPGGLVA-NSPDSPHLLADRISATVYIGGAENDPSFTADHAEKLDKAFS
Rv2765|M.tuberculosis_H37Rv FHPGGLVA-NSPDSPHLLADRISATVYIGGAENDPSFTADHAEKLDKAFS
MMAR_1955|M.marinum_M FHGGGLVT-DNPDSPHLLADRMTARLYVGGAQNDPSFTTDHAEQLEKALT
MUL_2177|M.ulcerans_Agy99 FHGGDLVT-DNPDSPHLLADRMTARLYVGGATNDPSFTTDHAEQLEKALT
MAV_3654|M.avium_104 FHGGGLVT-DSDDSPHLLADRMSATVYVGGAQDDASFTTDHAEQLDKALT
TH_0693|M.thermoresistible__bu FHAAGLVT-DDPTSPHLLAERIKATVYVAGAQDDDGFTPAHAETLGKALT
Mflv_4008|M.gilvum_PYR-GCK FHGGGLVT-DDAESPHLLADRIRAAVYVGAAHNDNSFTRADGETLDKALS
Mvan_2379|M.vanbaalenii_PYR-1 FHGGGLAT-DDPHSPHLLADQMRAAVYVGAARSDRSFTTEDGERLEKALT
MSMEG_2669|M.smegmatis_MC2_155 FHGGRIAVEDDPDSPHLLADKIQAVVYVAGAENDASFTEDDAKRLEDALS
MAB_3183c|M.abscessus_ATCC_199 FHGGNLAKADDLNSPHHLAGRITGVVLIAAAEEDASFPAEQEQLLGQVLT
MLBr_01444|M.leprae_Br4923 FYGTPLPR-------NLSETLNGACPIVASFGGRDPLGIGAPKRLRQATQ
*: : : . :.. : : * ..
Mb2787|M.bovis_AF2122/97 AAGVPHRIECYP-AAHGFAVPDNP---------SYDAAADERHWAAMTET
Rv2765|M.tuberculosis_H37Rv AAGVPHRIECYP-AAHGFAVPDNP---------SYDAAADERHWAAMTET
MMAR_1955|M.marinum_M AAGVEHTIEWYP-GAHGFAVPDNP---------PYDEACAQRHWTAMTDL
MUL_2177|M.ulcerans_Agy99 AAGVEHTIEWYP-GAHGFAVPDNP---------PYDEACAQRHWTAMTDL
MAV_3654|M.avium_104 AAGVRHTIEWYS-AAHGFAVPDNA---------PYDPAAAERHWDAMRDV
TH_0693|M.thermoresistible__bu DAGVEHTIEFYP-AGHGFAVPDNL---------PYDEQAAERHWDALRAL
Mflv_4008|M.gilvum_PYR-GCK AAGVEHTVDWYS-AQHGFAVPDNG---------PYDESAARRHWDAMQSF
Mvan_2379|M.vanbaalenii_PYR-1 STGVEHTIEWYP-AFHGFAVPDNG---------PYDEPAARRHWEAMRSF
MSMEG_2669|M.smegmatis_MC2_155 GASVEHTIEFYP-AGHGFAVPDHLS--------VYDEAAAQRHWENTERV
MAB_3183c|M.abscessus_ATCC_199 DAGVRHTIETYP-AKHGFAVTDNP---------TYDEGAAQRHWKALEDL
MLBr_01444|M.leprae_Br4923 TRHITTDIKVYPDAGHSFANKLPGQPLMRITGFGYNQAATEDAWSRVFAF
: :. *. . *.** *: . . *
Mb2787|M.bovis_AF2122/97 FGAALN--
Rv2765|M.tuberculosis_H37Rv FGAALN--
MMAR_1955|M.marinum_M FAATLSR-
MUL_2177|M.ulcerans_Agy99 FAATLSR-
MAV_3654|M.avium_104 FAAALPR-
TH_0693|M.thermoresistible__bu FDRELSG-
Mflv_4008|M.gilvum_PYR-GCK FAAHLV--
Mvan_2379|M.vanbaalenii_PYR-1 FATHLV--
MSMEG_2669|M.smegmatis_MC2_155 FGAALASA
MAB_3183c|M.abscessus_ATCC_199 YGATLGH-
MLBr_01444|M.leprae_Br4923 FDKHLRTD
: *