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PERQRRRYAPRLPREQRRQQLLDAALTVLADCPLHELSMEAVAEAAGVGKPVLYTAYRTRAELVTALLTR EHKRGLDQVRAALPNDLIVAGPTEAYTATVSAFLQSVLENPTRWRLILTVPDSAPREYRAAVRHARSQIV ALAESFARAGIELDPRLTNLDPELIGHTMLSFAEMLGRLAVHDPETYTRERLEQYAATTMKMFAGQFPVP T*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2368 | - | - | 100% (212) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0363 | - | 4e-16 | 35.71% (140) | TetR-family protein regulatory protein |
| M. smegmatis MC2 155 | MSMEG_1935 | - | 4e-11 | 36.94% (111) | TetR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0244 | - | 5e-18 | 32.39% (176) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0414 | - | 1e-16 | 34.44% (151) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0238 | - | 5e-18 | 32.39% (176) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02568 | - | 1e-15 | 33.80% (142) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4449c | - | 7e-14 | 32.88% (146) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0500 | - | 5e-17 | 35.71% (140) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4919 | - | 7e-17 | 32.76% (174) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0452 | - | 1e-11 | 37.84% (111) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_1163 | - | 4e-17 | 35.71% (140) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0257 | - | 1e-16 | 36.43% (140) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0244|M.bovis_AF2122/97 ------------------------MAGGTKR-----LPRAVREQQMLDAA
Rv0238|M.tuberculosis_H37Rv ------------------------MAGGTKR-----LPRAVREQQMLDAA
MMAR_0500|M.marinum_M ------------------------MAGGTKR-----LPRAIREQQMLDAA
MUL_1163|M.ulcerans_Agy99 ------------------------MAGGTKR-----LPRAIREQQMLDAA
MAV_4919|M.avium_104 ------------------------MAGGTKR-----LPRAVREQQMLDAA
MLBr_02568|M.leprae_Br4923 ------------------------MAGGAKR-----IPRAVREQQMLDAA
Mflv_0414|M.gilvum_PYR-GCK ------------------------MAGGTKR-----LPRAVREQQMLDAA
Mvan_0257|M.vanbaalenii_PYR-1 ------------------------MAGGTKR-----LPRAVREQQMLDAA
MAB_4449c|M.abscessus_ATCC_199 ------------------------MAGGTKR-----LPRAVREQQMLDAA
TH_0452|M.thermoresistible__bu MSEVADTTARQEITPTNGGTTSGAAAGANRRGNR--LPRDERRNQLLIAA
MSMEG_2368|M.smegmatis_MC2_155 ------------------------MPERQRRRYAPRLPREQRRQQLLDAA
. :* :** *.:*:* **
Mb0244|M.bovis_AF2122/97 VQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRF
Rv0238|M.tuberculosis_H37Rv VQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRF
MMAR_0500|M.marinum_M VQMFSANGYHETSMDTIAAAAQISKPMLYLYYGSKEDLFGACLNREMSRF
MUL_1163|M.ulcerans_Agy99 VQMFSANGYHETSMDTIAAAAQISKPMLYLYYGSKEDLFGACLNREMSRF
MAV_4919|M.avium_104 VQMFSVNGYHETSMDAIAAQAQISKPMLYLYYGSKEDLFGACLNRELGRF
MLBr_02568|M.leprae_Br4923 VQMFSVNGYHKTSMDAIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRF
Mflv_0414|M.gilvum_PYR-GCK VEIFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEELFGACLHRELTRF
Mvan_0257|M.vanbaalenii_PYR-1 VEIFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEELFGACLNRELGRF
MAB_4449c|M.abscessus_ATCC_199 VQEFALNGFRDTSMDAIAAAAKISKPMLYLYYGSKEDLFVACLRRELGRF
TH_0452|M.thermoresistible__bu SEVFVDRGYHAAGMDEIAERAGVSKPVLYQHFSSKLELYLAVLQRHVDNL
MSMEG_2368|M.smegmatis_MC2_155 LTVLADCPLHELSMEAVAEAAGVGKPVLYTAYRTRAELVTALLTREHKRG
: : .*: :* * :.**:** : :: :* * * *. .
Mb0244|M.bovis_AF2122/97 IDALRSSIN---FDQSPKDLLRNTIVSFLRYIDANRASWIVMYT-QATSS
Rv0238|M.tuberculosis_H37Rv IDALRSSIN---FDQSPKDLLRNTIVSFLRYIDANRASWIVMYT-QATSS
MMAR_0500|M.marinum_M IDAVRADID---LSQSPKDLLRNAIVSFLRYIDQNQASWIVMYT-QAVSS
MUL_1163|M.ulcerans_Agy99 IDAVRADID---LSQSPKDLLRNAIVSFLRYIDQNQASWIVMYT-QAVSS
MAV_4919|M.avium_104 IDAVRADID---FQQSPNDMLRNTIASFMRYIDANRASWIVMYT-QATSS
MLBr_02568|M.leprae_Br4923 IAMVRADID---FTQSPKDLLRNTIVSFLRYIDANRASWIVMYI-QAMSL
Mflv_0414|M.gilvum_PYR-GCK VDEVNSNID---FTAPPKELLRTAVLAFLNYIDANRASWMVLYT-QATSS
Mvan_0257|M.vanbaalenii_PYR-1 VDEVNSNID---FSAAPKELLRTAVLAFLKYIDANRASWMVLYT-QATSS
MAB_4449c|M.abscessus_ATCC_199 VEAVRGDID---LTQSPRDVLSTTVVSFLNYVDTHRASWIVIYG-QATST
TH_0452|M.thermoresistible__bu VSGVRQALR---TTTDNRQRLRAAVQAFFDFIEHDGQGYRLIFENDYVTE
MSMEG_2368|M.smegmatis_MC2_155 LDQVRAALPNDLIVAGPTEAYTATVSAFLQSVLENPTRWRLILTVPDSAP
: :. : : :: :*: : . : :: :
Mb0244|M.bovis_AF2122/97 QAFAHTVREGREQIVQLVAELVRAGTRGPL--TDAEIEMMAVALVGAGEA
Rv0238|M.tuberculosis_H37Rv QAFAHTVREGREQIVQLVAELVRAGTRGPL--TDAEIEMMAVALVGAGEA
MMAR_0500|M.marinum_M QAFAQTVREGREQIVELVAGMLRAGTRSPR--SDAEIDMMAAALVGAGEA
MUL_1163|M.ulcerans_Agy99 QAFAQTVREGREQIVELVAGMLRAGTRSPR--SDAEIDMMAAALVGAGEA
MAV_4919|M.avium_104 QAFAHMVREGREQIIELVAGLMRAGSRTPR--TDREHEMMAVALVGAGEA
MLBr_02568|M.leprae_Br4923 PAFAQTVREARDQITELVAGLMRVGTRSSR--PDHEYEIMAGALVGAGEA
Mflv_0414|M.gilvum_PYR-GCK QAFAHTVREGRERIIEIVGRLLRSGTRFPE--PDTDFDMMAVALVGAGEA
Mvan_0257|M.vanbaalenii_PYR-1 QAFAHTVREGRERIIELVGRLLRSGTKFPE--PDTDFELMAVALVGAGEA
MAB_4449c|M.abscessus_ATCC_199 QLFAKQVREGRDRIIELVARLIKAASPEID--PETDYDAMAVALVGGGEA
TH_0452|M.thermoresistible__bu PQVAAQVKVATEACTDAVFDLISQDSGLEA--HRARMIAVGLVAISVDCA
MSMEG_2368|M.smegmatis_MC2_155 REYRAAVRHARSQIVALAESFARAGIELDPRLTNLDPELIGHTMLSFAEM
*: . . . : :. . :.
Mb0244|M.bovis_AF2122/97 VATRLGIG-DTDVDEAAEMMINLFWLGLKGAPVDR-------LETGH---
Rv0238|M.tuberculosis_H37Rv VATRLGIG-DTDVDEAAEMMINLFWLGLKGAPVDR-------LETGH---
MMAR_0500|M.marinum_M VANRLSAG-DTDVDEAAEMMIDLFWRGLKGAPSDRE------IGSNFAAG
MUL_1163|M.ulcerans_Agy99 VANRLSAG-DTDVDEAAEMMIDLLWRGLKGAPSDRE------IGSNFAAG
MAV_4919|M.avium_104 VANRLSTG-DIDVDEAAALMIDLFWYGLKGSPEERE------AAAAQPEA
MLBr_02568|M.leprae_Br4923 MATRLTTG-DIAVDEAAELMINLFWHGLKGAPADRD------FGPSIVAG
Mflv_0414|M.gilvum_PYR-GCK IASRVSTG-DADVHEASELMINLFWRGLKGSPSAASDRDADATDATAVIT
Mvan_0257|M.vanbaalenii_PYR-1 IASRVSTG-DADVDEAAELMINLFWLGLKGAPSAAD------VDATAVIS
MAB_4449c|M.abscessus_ATCC_199 VASRVATG-DIKVESAKDTLLNLGWRGLRGRPRDEP------VAKRA---
TH_0452|M.thermoresistible__bu RYWLHADR-PISKEDAVEGTVQFAWGGLSHVPLTRS--------------
MSMEG_2368|M.smegmatis_MC2_155 LGRLAVHDPETYTRERLEQYAATTMKMFAGQFPVPT--------------
. :
Mb0244|M.bovis_AF2122/97 -------
Rv0238|M.tuberculosis_H37Rv -------
MMAR_0500|M.marinum_M -------
MUL_1163|M.ulcerans_Agy99 -------
MAV_4919|M.avium_104 DRSGAGG
MLBr_02568|M.leprae_Br4923 -------
Mflv_0414|M.gilvum_PYR-GCK S------
Mvan_0257|M.vanbaalenii_PYR-1 S------
MAB_4449c|M.abscessus_ATCC_199 -------
TH_0452|M.thermoresistible__bu -------
MSMEG_2368|M.smegmatis_MC2_155 -------