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MSQRASHAVTYNAFFAAAAAPPILIGDPARQHGPIRVEALAGHLQPELVEAAESRQVSAGEARPTGSVRH VEVFQMDGVGTSIIGRPRPLSRHRRADDLYTLNCEEPAKAIALGADVVAIARPLLAAAIDSAAAVADWLQ GFIDELRICLHGSGAPDLAAMHAIRLVDR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2340 | - | - | 100% (169) | hypothetical protein MSMEG_2340 |
| M. smegmatis MC2 155 | MSMEG_4789 | - | 1e-58 | 99.09% (110) | hypothetical protein MSMEG_4789 |
| M. smegmatis MC2 155 | MSMEG_6696 | - | 3e-58 | 99.09% (110) | hypothetical protein MSMEG_6696 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4187 | - | 3e-17 | 67.86% (56) | isopentenyl pyrophosphate isomerase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3242 | - | 1e-11 | 51.56% (64) | isopentenyl pyrophosphate isomerase |
| M. marinum M | MMAR_4812 | idi2 | 1e-16 | 69.49% (59) | isopentenyl pyrophosphate isomerase type 2 Idi2 |
| M. avium 104 | MAV_3894 | fni | 4e-20 | 69.35% (62) | isopentenyl pyrophosphate isomerase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0380 | idi2 | 2e-18 | 71.19% (59) | isopentenyl pyrophosphate isomerase |
| M. vanbaalenii PYR-1 | Mvan_2176 | - | 7e-16 | 64.29% (56) | isopentenyl pyrophosphate isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4812|M.marinum_M MTNDPA-EISSRKRRHIDVCLNDEVNYVGVTTGLERYRLPFNALTQTSLA
MUL_0380|M.ulcerans_Agy99 MTNDPA-EISSRKRRHIDVCLNDEVNYVGVTTGLERYRLPFNALTQTSLA
MAV_3894|M.avium_104 MD-----AMTHRKRRHIDVCLSDPVEFDGVTTGLDRYRLPYHALTQTSLG
Mflv_4187|M.gilvum_PYR-GCK MTPDPASALQHRKRRHIDVCLTDPVDYQTLTTGFERYQLPYNALTQTDLH
Mvan_2176|M.vanbaalenii_PYR-1 MTSDPGSALQHRKRRHIDVCLTEAVDYQSLTTGFERYRLPYNALTQTDLH
MAB_3242|M.abscessus_ATCC_1997 ------------------------MQYVTRTTGLERLDLPYMALPNSSLA
MSMEG_2340|M.smegmatis_MC2_155 -------------------------------------------MSQRASH
:.:
MMAR_4812|M.marinum_M DIDLSAEFFGAPLRAPVLIGAMTGGAELSATINRNLATAAQRLGIGMMLG
MUL_0380|M.ulcerans_Agy99 DIDLSAEFFGAPLRAPVLIGAMTGGAELSAMINRNLATAAQRLGIGMMLG
MAV_3894|M.avium_104 DIDVSTSFFGANLRAPILIGAMTGGAEMSKTINRNLAAAAQQLGIGMMLG
Mflv_4187|M.gilvum_PYR-GCK SVDLGTEFMGSRLRAPVLIGAMTGGAALSGIINRNLAEAAQQLGVGMMLG
Mvan_2176|M.vanbaalenii_PYR-1 SVDLSTEFLGSHLRAPVLIGAMTGGAALSGIINRNLAAAAQQLGIGMMLG
MAB_3242|M.abscessus_ATCC_1997 GVDLSTEFLGRRLAAPVLIGAMTGGAKLAATINRNLAAAAQELGIGMMLG
MSMEG_2340|M.smegmatis_MC2_155 AVTYN-AFFAAAAAPPILIGDPAR--------------------------
: . *:. .*:*** :
MMAR_4812|M.marinum_M SQRIMLDDARGQRAASSFAVREVAPDVLLIGNIGLAQLTKAAVPAVAAAL
MUL_0380|M.ulcerans_Agy99 SQRIMLDDARGQRAASSFAVREVAPDVLLIGNIGLAQLTKAAVPAVAAAL
MAV_3894|M.avium_104 SQRIMLDSALGERAADSFAVRDVAPDVLLFGNIGLSQLAKTAVPHLVKAL
Mflv_4187|M.gilvum_PYR-GCK SQRVMIDDAV---AAESFDVRGVAPDVLVIGNIGLAQLQPSMVPALAAAL
Mvan_2176|M.vanbaalenii_PYR-1 SQRVMIDDEA---AAASFEVRGVAPDILLIGNIGLAQLRSSMVPGLAAAL
MAB_3242|M.abscessus_ATCC_1997 SQRVMLVEPD---SADTFAVREVAPDILLIGNIGLAQLGNIAPAAQLNSL
MSMEG_2340|M.smegmatis_MC2_155 ----------------------------QHGPIRVEALAGHLQPELVEAA
* * : * . :
MMAR_4812|M.marinum_M RR-VGANALAVHANSLQEAMQHGGDTDFSGSLGRLRDAADLLDYPVLLKE
MUL_0380|M.ulcerans_Agy99 RR-VGANALAVHANSLQEAMQHGGDTDFSGSLGRLRDAADLLDYPVLLKE
MAV_3894|M.avium_104 DR-VGADALAVHTNPLQEAMQHNGDTDFSGSLSRLREAAAALDYPVLLKE
Mflv_4187|M.gilvum_PYR-GCK DR-VGANGLAVHTNPLQEAMQHNGDTDFSGSMSRLREVVDSLGYPVMLKE
Mvan_2176|M.vanbaalenii_PYR-1 DR-VGANGLAVHTNPLQEAMQHDGDTDFSGSIGRLCDVAGAIGYPVVLKE
MAB_3242|M.abscessus_ATCC_1997 VRRVGADALAVHTNPLQEAVQPGGDTDFTGQVYRLAELTHAVEFPVLLKE
MSMEG_2340|M.smegmatis_MC2_155 ES----------------RQVSAGEARPTGSVR-----------------
*:: :*.:
MMAR_4812|M.marinum_M VGHGIGAAAVAQLLRLPGGLPVSGIDVAGAGGTSWSRVEQLVRYGELRYP
MUL_0380|M.ulcerans_Agy99 VGHGIGAAAVAQLLRLPGGLPVSGIDVAGAGGTSWSRVEQLVRYGELRYP
MAV_3894|M.avium_104 VGHGIGGAAAAELVGGEGQPPVAGIDVAGAGGTSWSRVEQFVRYGELRYP
Mflv_4187|M.gilvum_PYR-GCK VGHGIGASAAAQLVD----CPVAAVDVAGAGGTSWARIEQFVRYGEVRYP
Mvan_2176|M.vanbaalenii_PYR-1 VGHGIGAAAAAELVG----CPIAAIDVAGAGGTSWARIEQFVRYGDVRYP
MAB_3242|M.abscessus_ATCC_1997 VGHGISGAAARRLGG----CRLAAIDVAGAGGTSWARVEQFVRFGAITSP
MSMEG_2340|M.smegmatis_MC2_155 --------------------HVEVFQMDGVGTSIIGRPRPLSRH------
: .:: *.* : .* . : *.
MMAR_4812|M.marinum_M ELADWGIPTAEAIVEVRQALPAVPLVASGGIRTGMDAAKAIALGADVVAI
MUL_0380|M.ulcerans_Agy99 ELADWGIPTAEAIVEVRQALPAVPLVASGGIRTGMDAAKSIALGADVVAI
MAV_3894|M.avium_104 DLADWGVPTARAIVEVRRLLPEIPLVASGGIRTGMDAAKAIALGADVVAV
Mflv_4187|M.gilvum_PYR-GCK ALAEWGIPTAQALTEVRGILPDVPLVASGGIRTGMDAAKALAMGAEVVAI
Mvan_2176|M.vanbaalenii_PYR-1 ALAEWGVPTAQALTEVRQMLPDVPLVASGGIRTGMDAAKALAMGARVVAV
MAB_3242|M.abscessus_ATCC_1997 ELAEWGIPTAEALVEVHAELPHMPLIGSGGIRTGMDAAKAIALGASVVSV
MSMEG_2340|M.smegmatis_MC2_155 -------RRADDLYTLNCEEP----------------AKAIALGADVVAI
* : :. * **::*:** **::
MMAR_4812|M.marinum_M ARPLLAPAIESATAVQGWLQLFLDELRVCLHCCGARDLTSLRDIGVTAIR
MUL_0380|M.ulcerans_Agy99 ARPLLAPAIESATAVQDWLQLFLDELRVCLHCCGAPDLTSLRDIGVTAIR
MAV_3894|M.avium_104 ARPLLPAAIESSAAVVDWLRPFIDELRVCLHGCGVADLAGLRAVELIRLA
Mflv_4187|M.gilvum_PYR-GCK ARPLLAPAVESVGAVVDWLQRFIDELLVCLHGSGAANLSALRERGVTELP
Mvan_2176|M.vanbaalenii_PYR-1 ARPLLAPAVESVEAVVDWLQRFIDELLVCLHGCGAANLSALRGRGVTELP
MAB_3242|M.abscessus_ATCC_1997 ALPLLAPAVQSPQAVVAWLQQFLDELRIAMHCADVSTIADLRRISLRPRS
MSMEG_2340|M.smegmatis_MC2_155 ARPLLAAAIDSAAAVADWLQGFIDELRICLHGSGAPDLAAMHAIRLVDR-
* ***..*::* ** **: *:*** :.:* ... :: :: :
MMAR_4812|M.marinum_M ---
MUL_0380|M.ulcerans_Agy99 ---
MAV_3894|M.avium_104 ---
Mflv_4187|M.gilvum_PYR-GCK ---
Mvan_2176|M.vanbaalenii_PYR-1 ---
MAB_3242|M.abscessus_ATCC_1997 SPR
MSMEG_2340|M.smegmatis_MC2_155 ---