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AVVAATDRSVRLEVTDRAPQERGDAARNRAAILDAARRLIAERGPDAVSTDDIAVEAGVGKGTLFRRFGT RAGLMMVLLDEDEKAHQDAFIFGPPPLGPGAPPLDRLLAYGRERMKFVREHHALLSDAARDPQARFGGPD TLHRSHVRMLLQAAGTTGDLDAQADALVALLDADYVAYQLERGRSCEVQAAAWADTARKLCGH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2295 | - | - | 100% (204) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1015 | - | e-114 | 100.00% (204) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3807 | - | 2e-10 | 35.33% (150) | TetR-type regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3081 | - | 6e-67 | 67.21% (183) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4309 | - | 1e-72 | 70.92% (196) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3055 | - | 6e-67 | 67.21% (183) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00316 | - | 3e-07 | 45.00% (60) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3418 | - | 5e-46 | 48.96% (192) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1637 | - | 2e-69 | 67.02% (191) | TetR family transcriptional regulator |
| M. avium 104 | MAV_3923 | - | 1e-70 | 70.11% (184) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2712 | - | 3e-68 | 65.15% (198) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_3399 | - | 1e-69 | 67.02% (191) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2038 | - | 5e-75 | 73.94% (188) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4309|M.gilvum_PYR-GCK --------------------MSAPENRNGLPVLSVAESGPSERAAERGDA
Mvan_2038|M.vanbaalenii_PYR-1 --------------------MSAAQDRNGLPVLPVLPEGDS-TPPERGDA
MSMEG_2295|M.smegmatis_MC2_155 --------------------MAVVAATDRSVRLEVTDRAPQ----ERGDA
Mb3081|M.bovis_AF2122/97 --------------------MSGAERLGDLPVFARQEPVPE-----RGDA
Rv3055|M.tuberculosis_H37Rv --------------------MSGAERLGDLPVFARQEPVPE-----RGDA
MMAR_1637|M.marinum_M --------------------MSGVEGLGELPVSARQE---------RGDA
MUL_3399|M.ulcerans_Agy99 MLQYLNGLWSDLFQPSYSAGVSGVEGLGELPVSARQE---------RGDA
MAV_3923|M.avium_104 --------------------MSGVEQRGQLRFCDPRVPAPE-----RGDA
TH_2712|M.thermoresistible__bu -----------------VSLMSADELLPARPATDVAAPTATTAPPEREDA
MAB_3418|M.abscessus_ATCC_1997 -----------MVRFIPSGYYQSVMPGQEIPLLSVDLAQNP--VRERAIA
MLBr_00316|M.leprae_Br4923 ----------------------MSVPRSGLSVQMAQPARPL-----RADA
* *
Mflv_4309|M.gilvum_PYR-GCK ARNRVLLLDAARRLVDERGADSVTTDDIANAAGVGKGTLFRRFGSRAGLM
Mvan_2038|M.vanbaalenii_PYR-1 ARNRALLLDAARRLVDERGAEAVTTDDIAAAAGVGKGTLFRRFGSRAGLM
MSMEG_2295|M.smegmatis_MC2_155 ARNRAAILDAARRLIAERGPDAVSTDDIAVEAGVGKGTLFRRFGTRAGLM
Mb3081|M.bovis_AF2122/97 ARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLM
Rv3055|M.tuberculosis_H37Rv ARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLM
MMAR_1637|M.marinum_M ARNRELLLQAARRLVAKRGAEAVTTDDIAAEAGVGKGTLFRRFGSRAGLM
MUL_3399|M.ulcerans_Agy99 ARNRELLLQAARRLVAKRGAEAVTTDDIAAEAGVGKGTLFRRFGSRAGLM
MAV_3923|M.avium_104 ARNRALLLDAARRLVAERGADAVTMDDVAAAAGVGKGTLFRRFGSRAGLM
TH_2712|M.thermoresistible__bu ARNRALLLDAARRLIAERGAEAVTMDDIAAAAGVGKGTLFRRFGSRAGLM
MAB_3418|M.abscessus_ATCC_1997 TRNRALLLDAARQLLDEVGPDGMSMDAVAHAAGVGKGTLFRRFGSRTGLL
MLBr_00316|M.leprae_Br4923 ARNRARILGVAYEAFATEG-LSVPIDEIARRAGVGAGTVYRHFPTKEALC
:*** :* .* . . * .:. * :* **** **::*:* :: .*
Mflv_4309|M.gilvum_PYR-GCK IVLLDEDEKAQQHALLFGPPPLGPGAPPLERLLAYGRHRLKFVDTHHALL
Mvan_2038|M.vanbaalenii_PYR-1 IVLLDEDEKALQQAFLFGPPPLGPEAPPLQRLLAYGRERLKFVDSHHALL
MSMEG_2295|M.smegmatis_MC2_155 MVLLDEDEKAHQDAFIFGPPPLGPGAPPLDRLLAYGRERMKFVREHHALL
Mb3081|M.bovis_AF2122/97 MVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLL
Rv3055|M.tuberculosis_H37Rv MVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLL
MMAR_1637|M.marinum_M MVLLDEDERASQQAFLFGPPPLGPEAAPLDRLIAFGRERICFVHAHHELL
MUL_3399|M.ulcerans_Agy99 MVLLDEDERASQQAFLFGPPPLGPEAAPLDRLIAFGRERICFVHAHHELL
MAV_3923|M.avium_104 MVLLDEDERAIQQAFLFGPPPLGPDAPPLDRLVAFGRERLRFAHTHHALL
TH_2712|M.thermoresistible__bu LELLHDDETAFQQAFMFGPPPLGPGAEPLERLLAYGRRRLQFVCDHHALL
MAB_3418|M.abscessus_ATCC_1997 LALLDHEEHIEQQAFMFGPPPLGPDAPPLTRLIAFGRARLAFLERHLDLA
MLBr_00316|M.leprae_Br4923 AAVIGDRMPHLVDDGYVLLKSAGPGEALFTYLRSLVLHWGATDRGLVDAL
:: . . . . ** : * :
Mflv_4309|M.gilvum_PYR-GCK SDVGRDPQMRFNAP-MTLHHSHVRLLLDEAETTGDLDAQAAALLALLDAD
Mvan_2038|M.vanbaalenii_PYR-1 SDVGRDLQMRFNAP-ATLHQSHVRLLLESAGTTGDLDAQATALLALLDAD
MSMEG_2295|M.smegmatis_MC2_155 SDAARDPQARFGGP-DTLHRSHVRMLLQAAGTTGDLDAQADALVALLDAD
Mb3081|M.bovis_AF2122/97 SEANRDPQTRHSAA-LSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVD
Rv3055|M.tuberculosis_H37Rv SEANRDPQTRHSAA-LSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVD
MMAR_1637|M.marinum_M SEANRNPLTRYGAA-ASVHRRHVRVLLESADTTGDLDVQTDALLALLDVD
MUL_3399|M.ulcerans_Agy99 SEANRNPLTRYGAA-ASVHRRHVRVLLESADTTGDLDVQTDALLALLDVD
MAV_3923|M.avium_104 SAANRDPRTRYGPP-SAVLRRHVRVLLAATHTTGDLDAQADALLALLDAD
TH_2712|M.thermoresistible__bu TDVSREPQTRFGPP-MTLHHTHIRSLLAAADADGDLDVQADALLALTDPD
MAB_3418|M.abscessus_ATCC_1997 RATTADTDAWHNAPPTLLVRAHIRALLAQLECTGDLDAQTHALMSIIDPG
MLBr_00316|M.leprae_Br4923 AGAGGIDILGVAPDAEDAFLTILSDLLYAAQYAG--TARTDVGVREVKSI
. : ** * .:: . : .
Mflv_4309|M.gilvum_PYR-GCK YVHHQRTDLGRSLESIADAWETVARKLCGT
Mvan_2038|M.vanbaalenii_PYR-1 YVHHQLHDRGRTLAELGDAWETVARKLCGS
MSMEG_2295|M.smegmatis_MC2_155 YVAYQLE-RGRSCEVQAAAWADTARKLCGH
Mb3081|M.bovis_AF2122/97 YVEHQLNAGGHTLQTLGDAWESLARKLCGR
Rv3055|M.tuberculosis_H37Rv YVEHQLNAGGHTLQTLGDAWESLARKLCGR
MMAR_1637|M.marinum_M YVEHQLNDRGHTLRTLGDAWEDLARKLCGR
MUL_3399|M.ulcerans_Agy99 YVEHQLNDRGHTLRTLGDAWEDLARKLCGR
MAV_3923|M.avium_104 YVHHQLNDHGHTLQTLGDAWESLARKLCGN
TH_2712|M.thermoresistible__bu YVRHQVTDRGVALDALADSWGDVARKLCRR
MAB_3418|M.abscessus_ATCC_1997 YVYFATNSNGQSVAQLGDAWEDLVHKLCAR
MLBr_00316|M.leprae_Br4923 LVGCQAMEAYNSALAERVTDVVVDGLRAAR
* : : .