For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_2099 (-)

annotation: ABC transporter, substrate binding protein
coordinates: 2175058 - 2176023
length: 321

KKFATVVVTVLIAASATACGADDGGEDGATQLLLLSQQTPFTAPSYFAEKLGYYDEANLDVEIRAFPTGT
TALEAWKSGIGDVVYSGAQPALLNYGNTDGTNYRMIQIATRSEPALILMANRSITSAKDLEGKKIATRIG
STSEWWLQRYLAHNKVDTSKVEIINLDSQQMPPALEIGDIDAFALYQPVGWQSQAVSGDKVHQLADATEV
PGVSDLTSYGVRPEMIEQNPEAAKAFVEATKRGADYVVAHPEEVGEFYATEFGANNEDTVRTIALFDFNP
AFDEDAVSMMQDLVDWSVEHGALTAGFDINDVIWTEAAGQ*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_2099--100% (321)ABC transporter, substrate binding protein
M. smegmatis MC2 155MSMEG_0114-1e-1324.45% (274) extracellular solute-binding protein, family protein 3
M. smegmatis MC2 155MSMEG_0550-2e-1323.75% (320) sulfonate binding protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_0723-1e-1024.28% (276) substrate-binding region of ABC-type glycine betaine transport
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2241-1e-1325.78% (287) putative nitrate ABC transporter, periplasmic protein
M. marinum M-----
M. avium 104MAV_0141-3e-1324.62% (264) sulfonate binding protein
M. thermoresistible (build 8)TH_2996-2e-0724.29% (317) PUTATIVE putative aliphatic sulfonates family ABC transporter,
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_0122-1e-1425.81% (279) substrate-binding region of ABC-type glycine betaine transport

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0723|M.gilvum_PYR-GCK          ----MRFKALLVALVAGMLALAGCSVGSGGQSGNDPEKPTIRIGYQTFPS
Mvan_0122|M.vanbaalenii_PYR-1       ----MKLKALLVVLVSAVLALAGCSVDNGGQHGDDSGKPTIRIGYQTFPS
MAB_2241|M.abscessus_ATCC_1997      ----MKRTALLASMLIALAT--GCSLDSGSGSSQE---VTVVIGYQSKTI
MAV_0141|M.avium_104                ---MRPRHLTALAVVAAVTAVSGCGSSSGTTTTKD-----LHLDYAYYNP
MSMEG_2099|M.smegmatis_MC2_155      ----MKKFATVVVTVLIAASATACGADDGGEDGAT---QLLLLSQQTPFT
TH_2996|M.thermoresistible__bu      MHTAIEMLRLTLATLISAAALTACGATQSPDSPGLPADAALPTEVPPDTT
                                                  :    :  .*.  ..           :         

Mflv_0723|M.gilvum_PYR-GCK          ----GDLIVKNNKWLEEALPDHN--------IKWVKFDSGADVNTAFVAD
Mvan_0122|M.vanbaalenii_PYR-1       ----GDLIVKNNKWLEEALPDYN--------IKWTKFDSGADVNTAFVAG
MAB_2241|M.abscessus_ATCC_1997      NTVTAGTLLRAQGYLEKRLGDLTSRTGTKYTVQWQDYDTGAPITAQMLAE
MAV_0141|M.avium_104                ----LSLVIRDQQLLEKKGYHVT----------WVLSQGSNKANEGLRSK
MSMEG_2099|M.smegmatis_MC2_155      ---APSYFAEKLGYYDEANLDVE----------IRAFPTGTTALEAWKSG
TH_2996|M.thermoresistible__bu      -----LVVADDANRLRTLLTLSGEQDRLTGEVSYANFSSGPLRLEAIRTG
                                           .                               .        : 

Mflv_0723|M.gilvum_PYR-GCK          ELDFGALGSSPVARGLSEPLNIPYQVAFILDVAGDNE-----ALVARNAA
Mvan_0122|M.vanbaalenii_PYR-1       ELDFGALGSSPVARGLSEPLNIPYKVAFVLDVAGDNE-----ALVVRNGA
MAB_2241|M.abscessus_ATCC_1997      KIDIGSMGDYPLLINGSKTQANEKARTELVSITGYNAKGSLNMVVVPPNS
MAV_0141|M.avium_104                ALDFGSTGGSPALLARAN--GTPIKTVDVYARGEWTA------LVVAKNS
MSMEG_2099|M.smegmatis_MC2_155      IGDVVYSGAQPALLNYGNTDGTNYRMIQIATRS--EP-----ALILMANR
TH_2996|M.thermoresistible__bu      NAHLGYVGDVPPILAHYS--DADVPIVGAVRRDGTGA-----LIATSPDS
                                      ..   *  *      .                         :      

Mflv_0723|M.gilvum_PYR-GCK          GITTIADLRDKRVATPFASTAHYSLLAALDQNGLSPN-DVQLIDLQPQAI
Mvan_0122|M.vanbaalenii_PYR-1       GVDTIAQLKGRRIGTPFASTAHYSLLAALDQNGLSAN-DVQLIDLQPQAI
MAB_2241|M.abscessus_ATCC_1997      AITELPELKGKKVSASVGSAGHGTLVRALRNDGLDPTRDVEVLNQQPQVG
MAV_0141|M.avium_104                PINAVADLKGKKVAVTKGTDPYFFLLQSLATAGLSPA-DIEIVNLQHADG
MSMEG_2099|M.smegmatis_MC2_155      SITSAKDLEGKKIATRIGSTSEWWLQRYLAHNKVDTS-KVEIINLDSQQM
TH_2996|M.thermoresistible__bu      GITSLSDLAGKRIGVNEGTSQQATLLRNLQSVGLGIG-DVEPVYLGLAEF
                                     :    :* .:::..  .:     *   *    :.   .:: :       

Mflv_0723|M.gilvum_PYR-GCK          LAAWERGDIDAAYTWLPT--LNELRKTGKDLITSRQLAAEGKPTLDLAVV
Mvan_0122|M.vanbaalenii_PYR-1       LAAWERGDIDAAYTWLPT--LDELRKTGRDLITSRQLADAGKPTLDLATV
MAB_2241|M.abscessus_ATCC_1997      ASALESGQVQALSQFVAW--PGLLVFQNKAKLLYDG-AELNVPTFHGVVV
MAV_0141|M.avium_104                KTALERGDVDAWSGLDPF--MAETIQQQGSRIIYRNPDFNSGGVLN---A
MSMEG_2099|M.smegmatis_MC2_155      PPALEIGDIDAFALYQPVGWQSQAVSGDKVHQLADATEVPGVSDLTSYGV
TH_2996|M.thermoresistible__bu      ADGLRAEQIQAAVLKQPDRARYLESTAAEGAIEIPNAPGANTGLNYLYAG
                                      . .  :::*     .                       .         

Mflv_0723|M.gilvum_PYR-GCK          SSEFAK-SHPEVVDTWRKQQARALDVIADDPAAAAKAIAAEVG-------
Mvan_0122|M.vanbaalenii_PYR-1       SDEFAS-AHPEAVDVWRQQQGRALDLIREDPQAAAEAIAAEIG-------
MAB_2241|M.abscessus_ATCC_1997      RRDYAT-QHPEVLDAFLQAQLDATDFIHEKSLEAARIVAEGSGLPQEVVY
MAV_0141|M.avium_104                REDFIT-AHPDSVQLVVDTYEEARKWAKTHPAELAALLASQAK-------
MSMEG_2099|M.smegmatis_MC2_155      RPEMIE-QNPEAAKAFVEATKRGADYVVAHPEEVGEFYATEFG-------
TH_2996|M.thermoresistible__bu      RDALIDPARAAAVREFVIAWYRAELWRNGHQDTWISEYLVKDQ-------
                                            ..            .      .                    

Mflv_0723|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0122|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2241|M.abscessus_ATCC_1997      LYNGPGGTSFDATLKPSLIEAFTSDVPYLKSIGDFADLNIDDFVHDGPLR
MAV_0141|M.avium_104                --------------------------------------------------
MSMEG_2099|M.smegmatis_MC2_155      --------------------------------------------------
TH_2996|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0723|M.gilvum_PYR-GCK          ----------------------LTPED-----------IEGQLTQTVFLT
Mvan_0122|M.vanbaalenii_PYR-1       ----------------------LTPQD-----------VAGQLKQMVFLT
MAB_2241|M.abscessus_ATCC_1997      QAYTTRAKNYETELAAMVNPLVLHPADGADPGQAAEIWFDGKDSTQVYPT
MAV_0141|M.avium_104                --------------------------------------------VSQSVA
MSMEG_2099|M.smegmatis_MC2_155      ------------------------------------------------AN
TH_2996|M.thermoresistible__bu      -----------------------------------------------HVD
                                                                                      

Mflv_0723|M.gilvum_PYR-GCK          PEQVASAEWLGDDGK---PGNLAANLQSASEFLAEQK-QIPAAAPLNTFQ
Mvan_0122|M.vanbaalenii_PYR-1       PQDISSTEWLGTEGN---PGNLAVNLESASQFLADQS-QIPAAAPLKTFQ
MAB_2241|M.abscessus_ATCC_1997      AQELLKAVNAANAAGRKVRAAYVADTELGTRWFADHARWVQDPAGLHPFT
MAV_0141|M.avium_104                QEELGRTALDIDPVPGDWLRAVLTRIEPLAVADGDIKSDDAGRNALNTLI
MSMEG_2099|M.smegmatis_MC2_155      NEDTVRTIALFDFNP-----AFDEDAVSMMQDLVDWSVEHGALTAGFDIN
TH_2996|M.thermoresistible__bu      VDDARKIVESDGVAS---IPGFTDEVVATQQETIDLLQQAGAFAGRELRA
                                     ::                               :               

Mflv_0723|M.gilvum_PYR-GCK          D----GLYTRGLPGVLTE----------
Mvan_0122|M.vanbaalenii_PYR-1       D----AVYTKGLPGALNE----------
MAB_2241|M.abscessus_ATCC_1997      TGAGAARYVAAHPGARPLDYAQALAAAS
MAV_0141|M.avium_104                EP----KYARQAR---------------
MSMEG_2099|M.smegmatis_MC2_155      D----VIWTEAAGQ--------------
TH_2996|M.thermoresistible__bu      RDEFDFRFADLTADSPTENRGGQP----
                                           :.