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M. smegmatis MC2 155 MSMEG_1994 (-)

annotation: HpcH/HpaI aldolase
coordinates: 2076502 - 2076633
length: 43

VNARYTTDTLRTARSFLFVPGNRPERFSKAVAAQPDVVVLDLE
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_1994--100% (43)HpcH/HpaI aldolase
M. smegmatis MC2 155MSMEG_4713-8e-0562.50% (32) HpcH/HpaI aldolase/citrate lyase family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_2556-4e-0557.14% (35) HpcH/HpaI aldolase
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_3845citE4e-0565.71% (35) citrate (pro-3s)-lyase (beta subunit) CitE
M. avium 104MAV_5074-2e-0755.56% (36) citrate lyase
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_3776citE2e-0565.71% (35) citrate (pro-3s)-lyase (beta subunit) CitE
M. vanbaalenii PYR-1Mvan_4087-3e-0560.00% (35) HpcH/HpaI aldolase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2556|M.gilvum_PYR-GCK          MTL-------APGTAWLFCPADRPERFEKAAAAA-DIVILDLEDGVAAKD
Mvan_4087|M.vanbaalenii_PYR-1       MTL-------AAGPAWLFCPADRPERFEKAAAAA-DVVILDLEDGVAAKD
MMAR_3845|M.marinum_M               MKLR------TAGPAWLFCPADRPERFAKAAAAA-DVVILDLEDGVAEAQ
MUL_3776|M.ulcerans_Agy99           MKLR------TASPAWLFCPADRPERFAKAAAAA-DVVILDLEDGVAEAQ
MSMEG_1994|M.smegmatis_MC2_155      MNARYTTDTLRTARSFLFVPGNRPERFSKAVAAQPDVVVLDLE-------
MAV_5074|M.avium_104                MHDD-----LASARSLLFVPGDRPDRFTKAASSDADGIIIDLEDAVAPEA
                                    *          .. : ** *.:**:** **.::  * :::***       

Mflv_2556|M.gilvum_PYR-GCK          RQAAREALVNTPLDPARTVVRVNPTGTADHGPDLEAVARTAYTTVMLAKT
Mvan_4087|M.vanbaalenii_PYR-1       REAARKALVDTPLDPSRTVVRVNPAGTPDHKLDLEALSRTSYTTVMLAKT
MMAR_3845|M.marinum_M               KPAARQALLDTPLDPERTIVRINAGDTDEQARDLAALAGTAYTTVMLPKA
MUL_3776|M.ulcerans_Agy99           KPAARQALLDTPLDPERTIVRINAGDTDEQARDLAALAGTAYTTVMLPKA
MSMEG_1994|M.smegmatis_MC2_155      --------------------------------------------------
MAV_5074|M.avium_104                KARAREAVDRWLATGGVGTVRINGTETPWHQEDLEMAARHG-CPVMVPKA
                                                                                      

Mflv_2556|M.gilvum_PYR-GCK          EAPEQVRALAP-----LDVIVLIETPLGALNVVDLARVDNAYALMWGAED
Mvan_4087|M.vanbaalenii_PYR-1       ESPQQVAALAP-----LDVVVLIETPLGALAVVELARVDNALALMWGAED
MMAR_3845|M.marinum_M               ESAAQLALLAP-----RDVIALVETARGALFAAEIAAADNTVGMMWGAED
MUL_3776|M.ulcerans_Agy99           ESVAQLALLAP-----RDVIALVETARGALFAAEIAAADNTVGMMWGAED
MSMEG_1994|M.smegmatis_MC2_155      --------------------------------------------------
MAV_5074|M.avium_104                RSASHLAQISRRLPTGTALIALIETAAGVLAAADICAVEGVVRAAFGSVD
                                                                                      

Mflv_2556|M.gilvum_PYR-GCK          LFAELGGTANRYPDGSYREVARHVRSQTLLAAKAYGRVA-LDSVFLDIKN
Mvan_4087|M.vanbaalenii_PYR-1       LFAVLGGTANRYPDGSYREVARHVRSQTLLAAKAYGRLA-LDSVFLDIKN
MMAR_3845|M.marinum_M               LIATLGGSSSRRGDGSYRDVARHVRSTTLLAASAFGRLA-LDAVHLDIGD
MUL_3776|M.ulcerans_Agy99           LIATLGGSSSRRGDGTYRDVARHVRSTILLAASAFGRLA-LDAVHLDIGD
MSMEG_1994|M.smegmatis_MC2_155      --------------------------------------------------
MAV_5074|M.avium_104                LGAELG------IDPEDHESLRYARSAVVLGSAAAGLAAPLDGVTTAVHD
                                                                                      

Mflv_2556|M.gilvum_PYR-GCK          LDGLRGEVDDAVAVGFDGKVAIHPTQLPVIRDGYTPTEAQADWARRVLAA
Mvan_4087|M.vanbaalenii_PYR-1       LDGLRAEVDDAVAVGFDVKVAIHPSQVAVIRSGYAPTDAEVDWARRVLDT
MMAR_3845|M.marinum_M               IDGLHAEAIDAATVGFDVTVCIHPSQVEVVRKAYRPDEEKLAWARRVLVA
MUL_3776|M.ulcerans_Agy99           VDGLHAEAMDAATVGFDVTVCIHPSQVEVVRKAYRPDEEKLAWARRVLVA
MSMEG_1994|M.smegmatis_MC2_155      --------------------------------------------------
MAV_5074|M.avium_104                EGAAGADAARAARLGFGGKLCIHPCQVAPVNSQFSPSIEEQAWARKVMAA
                                                                                      

Mflv_2556|M.gilvum_PYR-GCK          AQAERGVFQYEGQMVDMPVLRRAERIVALAP-----
Mvan_4087|M.vanbaalenii_PYR-1       ARTQRGVFAFEGIMVDAPVLRRAERIVELAPHPGA-
MMAR_3845|M.marinum_M               ARTERGVFAFEGQMVDSPVLRHAEMLLRRAGESVPA
MUL_3776|M.ulcerans_Agy99           ARTERGVFAFEGQMVDSPVLRHAEMLLRRAGESVPA
MSMEG_1994|M.smegmatis_MC2_155      ------------------------------------
MAV_5074|M.avium_104                G-SGNGARTVDGCMVDKPVVDRAARILARAQGLTSP