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MAKELRFNSDARARLEQGVNALADAVKVTLGPKGRNAILEKLTGPPTITNDGVTIAREIQLRDPFANMGA QLVKEVAMKTNGVVGDGTTTATVLAQAMVREGLAAVEAGANPMRVRRGIERTVPVVVESLRSHSVEVGSS SDLRRIAALAASDDEAIGDVIAAAVEHVGKTGVVTTEESDTLGMAVDVVDGIEFDHGYTSGYMVTDPERM EAVLDNPLILLTNKKISQVQEIMPTLEVAKRADRPLVVIAEDVDGPALQLLVGGNMHKTMQSVVVRAPGF GHRRVAELEDLAVALGGHVIAKDTGIDLGEVAREHLGSCDRLTATESDTTIVGPRGHQNLVDARVAQLEV QRERARIDADRDILDLRIARLTGRVAVIRVGGATSVELKERMLRVEDALAATRAALEAGIVSGGGTALAQ AHRVLDAVELVGDEAIGRDVVRRALSEPLRWIAFNAGFEGGDVVDVVADLPLGHGFNALTGEYGDMFEEG IIDPFKVTRAALESAASIAALLITTETAVVEEILGQPGAIMAPGFGDLAEGMVRPSNIY
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1978 | groEL | - | 100% (549) | chaperonin GroEL |
| M. smegmatis MC2 155 | MSMEG_0880 | groEL | e-149 | 51.29% (542) | chaperonin GroEL |
| M. smegmatis MC2 155 | MSMEG_1583 | groEL | e-138 | 50.00% (524) | chaperonin GroEL |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0448 | groEL | 1e-150 | 51.49% (538) | chaperonin GroEL |
| M. gilvum PYR-GCK | Mflv_0141 | groEL | 1e-149 | 51.48% (542) | chaperonin GroEL |
| M. tuberculosis H37Rv | Rv0440 | groEL | 1e-150 | 51.49% (538) | chaperonin GroEL |
| M. leprae Br4923 | MLBr_00317 | groEL | 1e-147 | 51.34% (522) | chaperonin GroEL |
| M. abscessus ATCC 19977 | MAB_0650 | groEL | 1e-147 | 50.92% (542) | chaperonin GroEL |
| M. marinum M | MMAR_0759 | groEL | 1e-146 | 50.92% (542) | 60 kDa chaperonin 2 GroEL2 |
| M. avium 104 | MAV_4707 | groEL | 1e-148 | 51.48% (542) | chaperonin GroEL |
| M. thermoresistible (build 8) | TH_0975 | groEL1 | 1e-147 | 51.11% (542) | 60 KDA CHAPERONIN 1 GROEL1 (PROTEIN CPN60-1) (GROEL |
| M. ulcerans Agy99 | MUL_1393 | groEL | 1e-146 | 50.74% (542) | chaperonin GroEL |
| M. vanbaalenii PYR-1 | Mvan_0764 | groEL | 1e-150 | 51.66% (542) | chaperonin GroEL |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0141|M.gilvum_PYR-GCK MAKTIAYDEEARRGLERGLNSLADAVKVTLGPKGRNVVLEKKWGAPTITN
Mvan_0764|M.vanbaalenii_PYR-1 MSKIIAYDEEARRGLERGLNALADAVKVTLGPKGRNVVLEKKWGAPTITN
MMAR_0759|M.marinum_M MAKTIAYDEEARRGLERGLNALADAVKVTLGPKGRNVVLEKKWGAPTITN
MUL_1393|M.ulcerans_Agy99 MAKTIAYDEEARRGLERGLNALADAVKVTLGPKGRNVVLEKKWGAPTITN
MAV_4707|M.avium_104 MAKTIAYDEEARRGLERGLNALADAVKVTLGPKGRNVVLEKKWGAPTITN
MAB_0650|M.abscessus_ATCC_1997 MAKTIAYDEEARRGLERGLNALADAVKVTLGPKGRNVVLEKKWGAPTITN
TH_0975|M.thermoresistible__bu MAKQIAYDEEARRGLERGLNALADAVKVTLGPKGRNVVLEKKWGAPTITN
Mb0448|M.bovis_AF2122/97 MAKTIAYDEEARRGLERGLNALADAVKVTLGPKGRNVVLEKKWGAPTITN
Rv0440|M.tuberculosis_H37Rv MAKTIAYDEEARRGLERGLNALADAVKVTLGPKGRNVVLEKKWGAPTITN
MLBr_00317|M.leprae_Br4923 MAKTIAYDEEARRGLERGLNSLADAVKVTLGPKGRNVVLEKKWGAPTITN
MSMEG_1978|M.smegmatis_MC2_155 MAKELRFNSDARARLEQGVNALADAVKVTLGPKGRNAILEKLTGPPTITN
*:* : ::.:** **:*:*:***************.:*** *.*****
Mflv_0141|M.gilvum_PYR-GCK DGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVR
Mvan_0764|M.vanbaalenii_PYR-1 DGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVR
MMAR_0759|M.marinum_M DGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVK
MUL_1393|M.ulcerans_Agy99 DGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVK
MAV_4707|M.avium_104 DGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVR
MAB_0650|M.abscessus_ATCC_1997 DGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVK
TH_0975|M.thermoresistible__bu DGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVK
Mb0448|M.bovis_AF2122/97 DGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVR
Rv0440|M.tuberculosis_H37Rv DGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVR
MLBr_00317|M.leprae_Br4923 DGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVK
MSMEG_1978|M.smegmatis_MC2_155 DGVTIAREIQLRDPFANMGAQLVKEVAMKTNGVVGDGTTTATVLAQAMVR
***:**:**:*.**: ::**:****** **:.*.*************:*:
Mflv_0141|M.gilvum_PYR-GCK EGLRNVAAGANPLGLKRGIEKAVEAVTQGLLKSAKEVETKEQIAATAAIS
Mvan_0764|M.vanbaalenii_PYR-1 EGLRNVAAGANPLGLKRGIEKAVEKVTETLLKSAKEVETKEQIAATAAIS
MMAR_0759|M.marinum_M EGLRNVAAGANPLGLKRGIEKAVEKVTETLLKSAKEVETKEQIAATAAIS
MUL_1393|M.ulcerans_Agy99 EGLRNVAAGANPLGLKRGIEKAVEKVTETLLKSAKEVETKEQIAATAAIS
MAV_4707|M.avium_104 EGLRNVAAGANPLGLKRGIEKAVEKVTETLLKSAKEVETKDQIAATAAIS
MAB_0650|M.abscessus_ATCC_1997 EGLRNVAAGANPLGLKRGIEKAVEKVTETLLKSAKEVETKEQIAATAGIS
TH_0975|M.thermoresistible__bu EGLRNVAAGANPLALKRGIEAAVEKVTETLLKSAKEVETKEQIANTAAIS
Mb0448|M.bovis_AF2122/97 EGLRNVAAGANPLGLKRGIEKAVEKVTETLLKGAKEVETKEQIAATAAIS
Rv0440|M.tuberculosis_H37Rv EGLRNVAAGANPLGLKRGIEKAVEKVTETLLKGAKEVETKEQIAATAAIS
MLBr_00317|M.leprae_Br4923 EGLRNVAAGANPLGLKRGIEKAVDKVTETLLKDAKEVETKEQIAATAAIS
MSMEG_1978|M.smegmatis_MC2_155 EGLAAVEAGANPMRVRRGIERTVPVVVESLRSHSVEVGSSSDLRRIAALA
*** * *****: ::**** :* *.: * . : ** :..:: *.::
Mflv_0141|M.gilvum_PYR-GCK AGD-VQIGELIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYIS
Mvan_0764|M.vanbaalenii_PYR-1 AGD-TQIGELIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYIS
MMAR_0759|M.marinum_M AGD-QSIGDLIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYIS
MUL_1393|M.ulcerans_Agy99 AGD-QSIGDLIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYIS
MAV_4707|M.avium_104 AGD-QSIGDLIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYIS
MAB_0650|M.abscessus_ATCC_1997 AGD-QSIGDLIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYIS
TH_0975|M.thermoresistible__bu AGD-QQIGELIAEAMDKVGNEGVITVEESQTFGLQLELTEGMRFDKGYIS
Mb0448|M.bovis_AF2122/97 AGD-QSIGDLIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYIS
Rv0440|M.tuberculosis_H37Rv AGD-QSIGDLIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYIS
MLBr_00317|M.leprae_Br4923 AGD-QSIGDLIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYIS
MSMEG_1978|M.smegmatis_MC2_155 ASDDEAIGDVIAAAVEHVGKTGVVTTEESDTLGMAVDVVDGIEFDHGYTS
*.* **::** *:::**: **:*.***:*:*: :::.:*:.**:** *
Mflv_0141|M.gilvum_PYR-GCK GYFVTDAERQEAVLEDPYILLVSSKVSTVKDLLPLLEKVIQAGKPLLIIA
Mvan_0764|M.vanbaalenii_PYR-1 GYFVTDAERQEAVLEDPYILLVSSKVSTVKDLLPLLEKVIQAGKPLLIIA
MMAR_0759|M.marinum_M GYFVTDAERQEAVLEDPYILLVSSKVSTVKDLLPLLEKVIQGGKPLLIIA
MUL_1393|M.ulcerans_Agy99 GYFVTDAERQEAVLEDPYILLVSSKVSTVKDLLPLLEKVIQGGKPLLIIA
MAV_4707|M.avium_104 GYFVTDAERQEAVLEDPFILLVSSKVSTVKDLLPLLEKVIQAGKPLLIIA
MAB_0650|M.abscessus_ATCC_1997 GYFVTDAERQEAVLEDPYILLVSSKVSTVKDLLPLLEKVIQAGKPLLIIA
TH_0975|M.thermoresistible__bu GYFVTDAERQEAVLEDPYILLVSSKVSTVKDLLPLLEKVIQSGKPLLIIA
Mb0448|M.bovis_AF2122/97 GYFVTDPERQEAVLEDPYILLVSSKVSTVKDLLPLLEKVIGAGKPLLIIA
Rv0440|M.tuberculosis_H37Rv GYFVTDPERQEAVLEDPYILLVSSKVSTVKDLLPLLEKVIGAGKPLLIIA
MLBr_00317|M.leprae_Br4923 GYFVTDAERQEAVLEEPYILLVSSKVSTVKDLLPLLEKVIQAGKSLLIIA
MSMEG_1978|M.smegmatis_MC2_155 GYMVTDPERMEAVLDNPLILLTNKKISQVQEIMPTLEVAKRADRPLVVIA
**:***.** ****::* ***...*:* *::::* ** . ..:.*::**
Mflv_0141|M.gilvum_PYR-GCK EDVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAILTGGQVV
Mvan_0764|M.vanbaalenii_PYR-1 EDVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDIAILTGGQVV
MMAR_0759|M.marinum_M EDVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAILTGGQVI
MUL_1393|M.ulcerans_Agy99 EDVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAILTGGQVI
MAV_4707|M.avium_104 EDVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAILTGGQVI
MAB_0650|M.abscessus_ATCC_1997 EDVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAILTGGQVV
TH_0975|M.thermoresistible__bu EDVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAILTGGQVI
Mb0448|M.bovis_AF2122/97 EDVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAILTGGQVI
Rv0440|M.tuberculosis_H37Rv EDVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAILTGGQVI
MLBr_00317|M.leprae_Br4923 EDVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAILTGAQVI
MSMEG_1978|M.smegmatis_MC2_155 EDVDGPALQLLVGGNMHKTMQSVVVRAPGFGHRRVAELEDLAVALGGHVI
***:* **. ** .::: *::**.*:*****.** * *:*:*: *.:*:
Mflv_0141|M.gilvum_PYR-GCK SEEVGLSLETADVALLGTARKVVVTKDETTIVEGAGDSDAIAGRVAQIRA
Mvan_0764|M.vanbaalenii_PYR-1 SEEVGLSLETADVALLGTARKVVVTKDETTIVEGAGDSDAIAGRVAQIRA
MMAR_0759|M.marinum_M SEEVGLSLETADISLLGKARKVVITKDETTIVEGAGDSDAIAGRVAQIRA
MUL_1393|M.ulcerans_Agy99 SEEVGLSLETADISLLGKARKVVITKDETTLVEGAGDSDAIAGRVAQIRA
MAV_4707|M.avium_104 SEEVGLSLESADISLLGKARKVVVTKDETTIVEGAGDSDAIAGRVAQIRT
MAB_0650|M.abscessus_ATCC_1997 SEEVGLSLETADITLLGTARKVVVTKDETTIVEGAGDSDAIAGRVAQIRS
TH_0975|M.thermoresistible__bu SEEVGLSLETADISLLGQARKVVVTKDETTIVEGAGDPDAIAGRVAQIRQ
Mb0448|M.bovis_AF2122/97 SEEVGLTLENADLSLLGKARKVVVTKDETTIVEGAGDTDAIAGRVAQIRQ
Rv0440|M.tuberculosis_H37Rv SEEVGLTLENADLSLLGKARKVVVTKDETTIVEGAGDTDAIAGRVAQIRQ
MLBr_00317|M.leprae_Br4923 SEEVGLTLENTDLSLLGKARKVVMTKDETTIVEGAGDTDAIAGRVAQIRT
MSMEG_1978|M.smegmatis_MC2_155 AKDTGIDLGEVAREHLGSCDRLTATESDTTIVGPRGHQNLVDARVAQLEV
:::.*: * . ** . ::. *:.:**:* *. : : .****:.
Mflv_0141|M.gilvum_PYR-GCK EIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVR
Mvan_0764|M.vanbaalenii_PYR-1 EIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVR
MMAR_0759|M.marinum_M EIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVR
MUL_1393|M.ulcerans_Agy99 EIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVR
MAV_4707|M.avium_104 EIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVR
MAB_0650|M.abscessus_ATCC_1997 EIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVR
TH_0975|M.thermoresistible__bu EIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVR
Mb0448|M.bovis_AF2122/97 EIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVR
Rv0440|M.tuberculosis_H37Rv EIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVR
MLBr_00317|M.leprae_Br4923 EIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVR
MSMEG_1978|M.smegmatis_MC2_155 QRERARIDADRDILDLRIARLTGRVAVIRVGGATSVELKERMLRVEDALA
: *.: * **: *: *:*:*:* ****:.*.**.****** *:***:
Mflv_0141|M.gilvum_PYR-GCK NAKAAVEEGIVAGGGVALLQSAPVLEDLGLSGDEATGANIVRVALSAPLK
Mvan_0764|M.vanbaalenii_PYR-1 NAKAAVEEGIVAGGGVALLQSAPSLDELNLTGDEATGANIVRVALSAPLK
MMAR_0759|M.marinum_M NAKAAVEEGIVAGGGVALLHAVPSLDELKLSGDEATGANIVRVALEAPLK
MUL_1393|M.ulcerans_Agy99 NAKAAVEEGIVAGGGVALLHAVPSLDELKLSGDEATGANIVRVALEAPLK
MAV_4707|M.avium_104 NAKAAVEEGIVAGGGVALLHAIPALDELKLEGDEATGANIVRVALEAPLK
MAB_0650|M.abscessus_ATCC_1997 NAKAAVEEGIVAGGGVALLQAAPSLDELSLTGDEATGAAIVKVAVEAPLK
TH_0975|M.thermoresistible__bu NAKAAVEEGIVAGGGVSLLQAAPVLDELKLEGDEATGVNIVRVALEAPLK
Mb0448|M.bovis_AF2122/97 NAKAAVEEGIVAGGGVTLLQAAPTLDELKLEGDEATGANIVKVALEAPLK
Rv0440|M.tuberculosis_H37Rv NAKAAVEEGIVAGGGVTLLQAAPTLDELKLEGDEATGANIVKVALEAPLK
MLBr_00317|M.leprae_Br4923 NAKAAVEEGIVAGGGVTLLQAAPALDKLKLTGDEATGANIVKVALEAPLK
MSMEG_1978|M.smegmatis_MC2_155 ATRAALEAGIVSGGGTALAQAHRVLDAVELVGDEAIGRDVVRRALSEPLR
::**:* ***:***.:* :: *: : * **** * :*: *:. **:
Mflv_0141|M.gilvum_PYR-GCK QIAFNGGLEPGVVAEKVSNLPAGHGLNAATGEYEDLLKAGVADPVKVTRS
Mvan_0764|M.vanbaalenii_PYR-1 QIAFNGGLEPGVVAEKVTNLPAGHGLNAATGEYEDLLKAGVADPVKVTRS
MMAR_0759|M.marinum_M QIAFNGGLEPGVVAEKVRNSPAGTGLNAATGVYEDLLKAGVADPVKVTRS
MUL_1393|M.ulcerans_Agy99 QIAFNGGLEPGVVAEKVRNSPVGTGLNAATGVYEDLLKAGVADPVKVTRS
MAV_4707|M.avium_104 QIAFNGGLEPGVVAEKVRNSPAGTGLNAATGEYEDLLKAGVADPVKVTRS
MAB_0650|M.abscessus_ATCC_1997 QIAFNSGLEPGVVAEKVRNSPSGTGLNAATGEYEDLLAAGVADPVKVTRS
TH_0975|M.thermoresistible__bu QIAANSGLEPGVVAEKVRNLEAGKGLNAATGEYEDLLAAGVADPVKVTRS
Mb0448|M.bovis_AF2122/97 QIAFNSGLEPGVVAEKVRNLPAGHGLNAQTGVYEDLLAAGVADPVKVTRS
Rv0440|M.tuberculosis_H37Rv QIAFNSGLEPGVVAEKVRNLPAGHGLNAQTGVYEDLLAAGVADPVKVTRS
MLBr_00317|M.leprae_Br4923 QIAFNSGMEPGVVAEKVRNLSVGHGLNAATGEYEDLLKAGVADPVKVTRS
MSMEG_1978|M.smegmatis_MC2_155 WIAFNAGFEGGDVVDVVADLPLGHGFNALTGEYGDMFEEGIIDPFKVTRA
** *.*:* * *.: * : * *:** ** * *:: *: **.****:
Mflv_0141|M.gilvum_PYR-GCK ALQNAASIAALFLTTEAVVAD----KPEKAAAP-AGDPTGGMGGMDF--
Mvan_0764|M.vanbaalenii_PYR-1 ALQNAASIAALFLTTEAVVAD----KPEKAAAP-AGDPTGGMGGMDF--
MMAR_0759|M.marinum_M ALQNAASIAGLFLTTEAVVAD----KPEKAAAP-AGDPTGGMGGMDF--
MUL_1393|M.ulcerans_Agy99 ALQNAASIAGLFLTTEAVVAD----KPEKAAAP-AGDPTGGMGGMDF--
MAV_4707|M.avium_104 ALQNAASIAGLFLTTEAVVAD----KPEKAAAP-AGDPTGGMGGMDF--
MAB_0650|M.abscessus_ATCC_1997 ALQNAASIAALFLTTEAVVAD----KPEKAAAP-AGDPTGGMGGMDF--
TH_0975|M.thermoresistible__bu ALQNAASIAALFLTTEAVVAD----KPEKAAAP-AGDPTGGMGGMDF--
Mb0448|M.bovis_AF2122/97 ALQNAASIAGLFLTTEAVVAD----KPEKEKAS-VPG-GGDMGGMDF--
Rv0440|M.tuberculosis_H37Rv ALQNAASIAGLFLTTEAVVAD----KPEKEKAS-VPG-GGDMGGMDF--
MLBr_00317|M.leprae_Br4923 ALQNAASIAGLFLTTEAVVAD----KPEKTAAP-ASDPTGGMGGMDF--
MSMEG_1978|M.smegmatis_MC2_155 ALESAASIAALLITTETAVVEEILGQPGAIMAPGFGDLAEGMVRPSNIY
**:.*****.*::***:.*.: :* *. . .* .