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M. marinum M MMAR_0759 (groEL)

annotation: 60 kDa chaperonin 2 GroEL2
coordinates: 913752 - 915377
length: 541

MAKTIAYDEEARRGLERGLNALADAVKVTLGPKGRNVVLEKKWGAPTITNDGVSIAKEIELEDPYEKIGA
ELVKEVAKKTDDVAGDGTTTATVLAQALVKEGLRNVAAGANPLGLKRGIEKAVEKVTETLLKSAKEVETK
EQIAATAAISAGDQSIGDLIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYISGYFVTDAERQE
AVLEDPYILLVSSKVSTVKDLLPLLEKVIQGGKPLLIIAEDVEGEALSTLVVNKIRGTFKSVAVKAPGFG
DRRKAMLQDMAILTGGQVISEEVGLSLETADISLLGKARKVVITKDETTIVEGAGDSDAIAGRVAQIRAE
IENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRNAKAAVEEGIVAGGGVALLHA
VPSLDELKLSGDEATGANIVRVALEAPLKQIAFNGGLEPGVVAEKVRNSPAGTGLNAATGVYEDLLKAGV
ADPVKVTRSALQNAASIAGLFLTTEAVVADKPEKAAAPAGDPTGGMGGMDF
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_0759groEL-100% (541)60 kDa chaperonin 2 GroEL2
M. marinum MMMAR_1126groELe-17960.85% (539) 60 kDa chaperone (GroEL1)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0448groEL0.094.29% (543) chaperonin GroEL
M. gilvum PYR-GCKMflv_0141groEL0.095.01% (541) chaperonin GroEL
M. tuberculosis H37RvRv0440groEL0.094.29% (543) chaperonin GroEL
M. leprae Br4923MLBr_00317groEL0.094.45% (541) chaperonin GroEL
M. abscessus ATCC 19977MAB_0650groEL0.096.49% (541) chaperonin GroEL
M. avium 104MAV_4707groEL0.097.97% (541) chaperonin GroEL
M. smegmatis MC2 155MSMEG_0880groEL0.095.75% (541) chaperonin GroEL
M. thermoresistible (build 8)TH_0975groEL10.095.19% (541) 60 KDA CHAPERONIN 1 GROEL1 (PROTEIN CPN60-1) (GROEL
M. ulcerans Agy99MUL_1393groEL0.099.63% (541) chaperonin GroEL
M. vanbaalenii PYR-1Mvan_0764groEL0.095.56% (541) chaperonin GroEL

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_0759|M.marinum_M               MAKTIAYDEEARRGLERGLNALADAVKVTLGPKGRNVVLEKKWGAPTITN
MUL_1393|M.ulcerans_Agy99           MAKTIAYDEEARRGLERGLNALADAVKVTLGPKGRNVVLEKKWGAPTITN
MAV_4707|M.avium_104                MAKTIAYDEEARRGLERGLNALADAVKVTLGPKGRNVVLEKKWGAPTITN
Mflv_0141|M.gilvum_PYR-GCK          MAKTIAYDEEARRGLERGLNSLADAVKVTLGPKGRNVVLEKKWGAPTITN
Mvan_0764|M.vanbaalenii_PYR-1       MSKIIAYDEEARRGLERGLNALADAVKVTLGPKGRNVVLEKKWGAPTITN
MSMEG_0880|M.smegmatis_MC2_155      MAKTIAYDEEARRGLERGLNSLADAVKVTLGPKGRNVVLEKKWGAPTITN
MAB_0650|M.abscessus_ATCC_1997      MAKTIAYDEEARRGLERGLNALADAVKVTLGPKGRNVVLEKKWGAPTITN
TH_0975|M.thermoresistible__bu      MAKQIAYDEEARRGLERGLNALADAVKVTLGPKGRNVVLEKKWGAPTITN
Mb0448|M.bovis_AF2122/97            MAKTIAYDEEARRGLERGLNALADAVKVTLGPKGRNVVLEKKWGAPTITN
Rv0440|M.tuberculosis_H37Rv         MAKTIAYDEEARRGLERGLNALADAVKVTLGPKGRNVVLEKKWGAPTITN
MLBr_00317|M.leprae_Br4923          MAKTIAYDEEARRGLERGLNSLADAVKVTLGPKGRNVVLEKKWGAPTITN
                                    *:* ****************:*****************************

MMAR_0759|M.marinum_M               DGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVK
MUL_1393|M.ulcerans_Agy99           DGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVK
MAV_4707|M.avium_104                DGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVR
Mflv_0141|M.gilvum_PYR-GCK          DGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVR
Mvan_0764|M.vanbaalenii_PYR-1       DGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVR
MSMEG_0880|M.smegmatis_MC2_155      DGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVR
MAB_0650|M.abscessus_ATCC_1997      DGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVK
TH_0975|M.thermoresistible__bu      DGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVK
Mb0448|M.bovis_AF2122/97            DGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVR
Rv0440|M.tuberculosis_H37Rv         DGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVR
MLBr_00317|M.leprae_Br4923          DGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVK
                                    *************************************************:

MMAR_0759|M.marinum_M               EGLRNVAAGANPLGLKRGIEKAVEKVTETLLKSAKEVETKEQIAATAAIS
MUL_1393|M.ulcerans_Agy99           EGLRNVAAGANPLGLKRGIEKAVEKVTETLLKSAKEVETKEQIAATAAIS
MAV_4707|M.avium_104                EGLRNVAAGANPLGLKRGIEKAVEKVTETLLKSAKEVETKDQIAATAAIS
Mflv_0141|M.gilvum_PYR-GCK          EGLRNVAAGANPLGLKRGIEKAVEAVTQGLLKSAKEVETKEQIAATAAIS
Mvan_0764|M.vanbaalenii_PYR-1       EGLRNVAAGANPLGLKRGIEKAVEKVTETLLKSAKEVETKEQIAATAAIS
MSMEG_0880|M.smegmatis_MC2_155      EGLRNVAAGANPLGLKRGIEKAVEKVTETLLKSAKEVETKEQIAATAGIS
MAB_0650|M.abscessus_ATCC_1997      EGLRNVAAGANPLGLKRGIEKAVEKVTETLLKSAKEVETKEQIAATAGIS
TH_0975|M.thermoresistible__bu      EGLRNVAAGANPLALKRGIEAAVEKVTETLLKSAKEVETKEQIANTAAIS
Mb0448|M.bovis_AF2122/97            EGLRNVAAGANPLGLKRGIEKAVEKVTETLLKGAKEVETKEQIAATAAIS
Rv0440|M.tuberculosis_H37Rv         EGLRNVAAGANPLGLKRGIEKAVEKVTETLLKGAKEVETKEQIAATAAIS
MLBr_00317|M.leprae_Br4923          EGLRNVAAGANPLGLKRGIEKAVDKVTETLLKDAKEVETKEQIAATAAIS
                                    *************.****** **: **: ***.*******:*** **.**

MMAR_0759|M.marinum_M               AGDQSIGDLIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYISG
MUL_1393|M.ulcerans_Agy99           AGDQSIGDLIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYISG
MAV_4707|M.avium_104                AGDQSIGDLIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYISG
Mflv_0141|M.gilvum_PYR-GCK          AGDVQIGELIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYISG
Mvan_0764|M.vanbaalenii_PYR-1       AGDTQIGELIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYISG
MSMEG_0880|M.smegmatis_MC2_155      AGDQSIGDLIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYISG
MAB_0650|M.abscessus_ATCC_1997      AGDQSIGDLIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYISG
TH_0975|M.thermoresistible__bu      AGDQQIGELIAEAMDKVGNEGVITVEESQTFGLQLELTEGMRFDKGYISG
Mb0448|M.bovis_AF2122/97            AGDQSIGDLIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYISG
Rv0440|M.tuberculosis_H37Rv         AGDQSIGDLIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYISG
MLBr_00317|M.leprae_Br4923          AGDQSIGDLIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYISG
                                    *** .**:********************:*********************

MMAR_0759|M.marinum_M               YFVTDAERQEAVLEDPYILLVSSKVSTVKDLLPLLEKVIQGGKPLLIIAE
MUL_1393|M.ulcerans_Agy99           YFVTDAERQEAVLEDPYILLVSSKVSTVKDLLPLLEKVIQGGKPLLIIAE
MAV_4707|M.avium_104                YFVTDAERQEAVLEDPFILLVSSKVSTVKDLLPLLEKVIQAGKPLLIIAE
Mflv_0141|M.gilvum_PYR-GCK          YFVTDAERQEAVLEDPYILLVSSKVSTVKDLLPLLEKVIQAGKPLLIIAE
Mvan_0764|M.vanbaalenii_PYR-1       YFVTDAERQEAVLEDPYILLVSSKVSTVKDLLPLLEKVIQAGKPLLIIAE
MSMEG_0880|M.smegmatis_MC2_155      YFVTDAERQEAVLEDPYILLVSSKVSTVKDLLPLLEKVIQSGKPLLIIAE
MAB_0650|M.abscessus_ATCC_1997      YFVTDAERQEAVLEDPYILLVSSKVSTVKDLLPLLEKVIQAGKPLLIIAE
TH_0975|M.thermoresistible__bu      YFVTDAERQEAVLEDPYILLVSSKVSTVKDLLPLLEKVIQSGKPLLIIAE
Mb0448|M.bovis_AF2122/97            YFVTDPERQEAVLEDPYILLVSSKVSTVKDLLPLLEKVIGAGKPLLIIAE
Rv0440|M.tuberculosis_H37Rv         YFVTDPERQEAVLEDPYILLVSSKVSTVKDLLPLLEKVIGAGKPLLIIAE
MLBr_00317|M.leprae_Br4923          YFVTDAERQEAVLEEPYILLVSSKVSTVKDLLPLLEKVIQAGKSLLIIAE
                                    *****.********:*:********************** .**.******

MMAR_0759|M.marinum_M               DVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAILTGGQVIS
MUL_1393|M.ulcerans_Agy99           DVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAILTGGQVIS
MAV_4707|M.avium_104                DVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAILTGGQVIS
Mflv_0141|M.gilvum_PYR-GCK          DVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAILTGGQVVS
Mvan_0764|M.vanbaalenii_PYR-1       DVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDIAILTGGQVVS
MSMEG_0880|M.smegmatis_MC2_155      DVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAILTGGQVIS
MAB_0650|M.abscessus_ATCC_1997      DVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAILTGGQVVS
TH_0975|M.thermoresistible__bu      DVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAILTGGQVIS
Mb0448|M.bovis_AF2122/97            DVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAILTGGQVIS
Rv0440|M.tuberculosis_H37Rv         DVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAILTGGQVIS
MLBr_00317|M.leprae_Br4923          DVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAILTGAQVIS
                                    ***************************************:*****.**:*

MMAR_0759|M.marinum_M               EEVGLSLETADISLLGKARKVVITKDETTIVEGAGDSDAIAGRVAQIRAE
MUL_1393|M.ulcerans_Agy99           EEVGLSLETADISLLGKARKVVITKDETTLVEGAGDSDAIAGRVAQIRAE
MAV_4707|M.avium_104                EEVGLSLESADISLLGKARKVVVTKDETTIVEGAGDSDAIAGRVAQIRTE
Mflv_0141|M.gilvum_PYR-GCK          EEVGLSLETADVALLGTARKVVVTKDETTIVEGAGDSDAIAGRVAQIRAE
Mvan_0764|M.vanbaalenii_PYR-1       EEVGLSLETADVALLGTARKVVVTKDETTIVEGAGDSDAIAGRVAQIRAE
MSMEG_0880|M.smegmatis_MC2_155      EEVGLSLETADVSLLGKARKVVVTKDETTIVEGAGDAEAIQGRVAQIRAE
MAB_0650|M.abscessus_ATCC_1997      EEVGLSLETADITLLGTARKVVVTKDETTIVEGAGDSDAIAGRVAQIRSE
TH_0975|M.thermoresistible__bu      EEVGLSLETADISLLGQARKVVVTKDETTIVEGAGDPDAIAGRVAQIRQE
Mb0448|M.bovis_AF2122/97            EEVGLTLENADLSLLGKARKVVVTKDETTIVEGAGDTDAIAGRVAQIRQE
Rv0440|M.tuberculosis_H37Rv         EEVGLTLENADLSLLGKARKVVVTKDETTIVEGAGDTDAIAGRVAQIRQE
MLBr_00317|M.leprae_Br4923          EEVGLTLENTDLSLLGKARKVVMTKDETTIVEGAGDTDAIAGRVAQIRTE
                                    *****:**.:*::*** *****:******:******.:** ******* *

MMAR_0759|M.marinum_M               IENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRN
MUL_1393|M.ulcerans_Agy99           IENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRN
MAV_4707|M.avium_104                IENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRN
Mflv_0141|M.gilvum_PYR-GCK          IENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRN
Mvan_0764|M.vanbaalenii_PYR-1       IENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRN
MSMEG_0880|M.smegmatis_MC2_155      IENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRN
MAB_0650|M.abscessus_ATCC_1997      IENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRN
TH_0975|M.thermoresistible__bu      IENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRN
Mb0448|M.bovis_AF2122/97            IENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRN
Rv0440|M.tuberculosis_H37Rv         IENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRN
MLBr_00317|M.leprae_Br4923          IENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRN
                                    **************************************************

MMAR_0759|M.marinum_M               AKAAVEEGIVAGGGVALLHAVPSLDELKLSGDEATGANIVRVALEAPLKQ
MUL_1393|M.ulcerans_Agy99           AKAAVEEGIVAGGGVALLHAVPSLDELKLSGDEATGANIVRVALEAPLKQ
MAV_4707|M.avium_104                AKAAVEEGIVAGGGVALLHAIPALDELKLEGDEATGANIVRVALEAPLKQ
Mflv_0141|M.gilvum_PYR-GCK          AKAAVEEGIVAGGGVALLQSAPVLEDLGLSGDEATGANIVRVALSAPLKQ
Mvan_0764|M.vanbaalenii_PYR-1       AKAAVEEGIVAGGGVALLQSAPSLDELNLTGDEATGANIVRVALSAPLKQ
MSMEG_0880|M.smegmatis_MC2_155      AKAAVEEGIVAGGGVALLQSAPSLEELSLTGDEATGANIVRVALSAPLKQ
MAB_0650|M.abscessus_ATCC_1997      AKAAVEEGIVAGGGVALLQAAPSLDELSLTGDEATGAAIVKVAVEAPLKQ
TH_0975|M.thermoresistible__bu      AKAAVEEGIVAGGGVSLLQAAPVLDELKLEGDEATGVNIVRVALEAPLKQ
Mb0448|M.bovis_AF2122/97            AKAAVEEGIVAGGGVTLLQAAPTLDELKLEGDEATGANIVKVALEAPLKQ
Rv0440|M.tuberculosis_H37Rv         AKAAVEEGIVAGGGVTLLQAAPTLDELKLEGDEATGANIVKVALEAPLKQ
MLBr_00317|M.leprae_Br4923          AKAAVEEGIVAGGGVTLLQAAPALDKLKLTGDEATGANIVKVALEAPLKQ
                                    ***************:**:: * *:.* * ******. **:**:.*****

MMAR_0759|M.marinum_M               IAFNGGLEPGVVAEKVRNSPAGTGLNAATGVYEDLLKAGVADPVKVTRSA
MUL_1393|M.ulcerans_Agy99           IAFNGGLEPGVVAEKVRNSPVGTGLNAATGVYEDLLKAGVADPVKVTRSA
MAV_4707|M.avium_104                IAFNGGLEPGVVAEKVRNSPAGTGLNAATGEYEDLLKAGVADPVKVTRSA
Mflv_0141|M.gilvum_PYR-GCK          IAFNGGLEPGVVAEKVSNLPAGHGLNAATGEYEDLLKAGVADPVKVTRSA
Mvan_0764|M.vanbaalenii_PYR-1       IAFNGGLEPGVVAEKVTNLPAGHGLNAATGEYEDLLKAGVADPVKVTRSA
MSMEG_0880|M.smegmatis_MC2_155      IALNGGLEPGVVAEKVSNLPAGHGLNAATGEYEDLLAAGVADPVKVTRSA
MAB_0650|M.abscessus_ATCC_1997      IAFNSGLEPGVVAEKVRNSPSGTGLNAATGEYEDLLAAGVADPVKVTRSA
TH_0975|M.thermoresistible__bu      IAANSGLEPGVVAEKVRNLEAGKGLNAATGEYEDLLAAGVADPVKVTRSA
Mb0448|M.bovis_AF2122/97            IAFNSGLEPGVVAEKVRNLPAGHGLNAQTGVYEDLLAAGVADPVKVTRSA
Rv0440|M.tuberculosis_H37Rv         IAFNSGLEPGVVAEKVRNLPAGHGLNAQTGVYEDLLAAGVADPVKVTRSA
MLBr_00317|M.leprae_Br4923          IAFNSGMEPGVVAEKVRNLSVGHGLNAATGEYEDLLKAGVADPVKVTRSA
                                    ** *.*:********* *   * **** ** ***** *************

MMAR_0759|M.marinum_M               LQNAASIAGLFLTTEAVVADKPEKAAAPAGDPTGGMGGMDF
MUL_1393|M.ulcerans_Agy99           LQNAASIAGLFLTTEAVVADKPEKAAAPAGDPTGGMGGMDF
MAV_4707|M.avium_104                LQNAASIAGLFLTTEAVVADKPEKAAAPAGDPTGGMGGMDF
Mflv_0141|M.gilvum_PYR-GCK          LQNAASIAALFLTTEAVVADKPEKAAAPAGDPTGGMGGMDF
Mvan_0764|M.vanbaalenii_PYR-1       LQNAASIAALFLTTEAVVADKPEKAAAPAGDPTGGMGGMDF
MSMEG_0880|M.smegmatis_MC2_155      LQNAASIAALFLTTEAVVADKPEKAAAPAGDPTGGMGGMDF
MAB_0650|M.abscessus_ATCC_1997      LQNAASIAALFLTTEAVVADKPEKAAAPAGDPTGGMGGMDF
TH_0975|M.thermoresistible__bu      LQNAASIAALFLTTEAVVADKPEKAAAPAGDPTGGMGGMDF
Mb0448|M.bovis_AF2122/97            LQNAASIAGLFLTTEAVVADKPEKEKASVPG-GGDMGGMDF
Rv0440|M.tuberculosis_H37Rv         LQNAASIAGLFLTTEAVVADKPEKEKASVPG-GGDMGGMDF
MLBr_00317|M.leprae_Br4923          LQNAASIAGLFLTTEAVVADKPEKTAAPASDPTGGMGGMDF
                                    ********.***************  *.. .  *.******