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QPVVEMRGISIEFPGVKALDGVDFRLLPGEVHALMGENGAGKSTLIKALTGVYDIDDGTIVVAGTPCTFA GPRQAQEAGISTVYQEVNLCPNLTVGENILLGREPRRWGRIDYRTLNRRARELLAELELDIDPRSQLGSH PIAIQQLVAIARATAVRAQVLILDEPTSSLDAREVGELFRVIRRLRDSGTAILFVSHFLDQIYAISDRMT VLRNGKLVGEYLTAELPKSDLVAAMLGRQLDVLDEVAEAANVTAETAEHQSETLVRADALGRVPAVHPVT LDIGRGEILGLAGLLGSGRTELARLLFGADRATSGHVEIRGRRVALRTPRSAIAHGFAFTSENRKDEGVV GDLSVRENLVLALQARRGFARPLSTKTKDQLVAKYLDALDIRPRNPDTLLKNLSGGNQQKVLLARWLITE PDLFILDEPTRGIDVGAKTQIQKLVTELAGDGMAIVFISAELDEVTRISTRIAVMRDRHNVALAEAGTSP SKLTALIAGTS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1711 | - | - | 100% (502) | ATP binding protein of ABC transporter |
| M. smegmatis MC2 155 | MSMEG_3602 | - | 1e-95 | 40.51% (474) | ribose transport ATP-binding protein RbsA |
| M. smegmatis MC2 155 | MSMEG_4170 | - | 6e-91 | 40.51% (474) | ribose transport ATP-binding protein RbsA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3687c | dppD | 3e-30 | 27.43% (514) | peptide ABC transporter ATP-binding protein |
| M. gilvum PYR-GCK | Mflv_2758 | - | 2e-37 | 29.22% (510) | AAA ATPase |
| M. tuberculosis H37Rv | Rv3663c | dppD | 3e-30 | 27.43% (514) | peptide ABC transporter ATP-binding protein |
| M. leprae Br4923 | MLBr_02352 | - | 3e-18 | 29.86% (211) | putative antibiotic resistance efflux protein |
| M. abscessus ATCC 19977 | MAB_0429 | - | 2e-37 | 28.79% (528) | putative oligopeptide ABC transporter, ATP-binding protein |
| M. marinum M | MMAR_5151 | dppD | 2e-31 | 28.82% (517) | dipeptide-transport ATP-binding protein ABC transporter DppD |
| M. avium 104 | MAV_3418 | - | 7e-39 | 29.26% (499) | ABC transporter, ATP-binding protein DppD |
| M. thermoresistible (build 8) | TH_4070 | - | 9e-40 | 31.76% (507) | PUTATIVE ABC transporter related |
| M. ulcerans Agy99 | MUL_4237 | dppD | 3e-31 | 28.82% (517) | dipeptide-transport ATP-binding protein ABC transporter DppD |
| M. vanbaalenii PYR-1 | Mvan_5292 | - | 3e-41 | 35.62% (233) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_1711|M.smegmatis_MC2_155 -----MQPVVEMRGISIEFPGVKA----LDG--VDFRLLPGEVHALMGEN
Mvan_5292|M.vanbaalenii_PYR-1 --MDTQPPILELRGVNKSFGVVHV----LHD--VDFCVYPGQVTALVGDN
Mflv_2758|M.gilvum_PYR-GCK ------MTVLNVQDLSVRIGART----IVDS--VSFAVEREKTVGIVGES
TH_4070|M.thermoresistible__bu ---VVTGPVLDVRDLRVRIGRRE----IVRG--VSFAVARGQTLGIVGES
MAB_0429|M.abscessus_ATCC_1997 MEVPTSDSVVDITGLTVDFEVDKQWVPAVKG--VSLSVAKGEVLAIVGES
Mb3687c|M.bovis_AF2122/97 -MSVPAAPLLSVEGLEVTFGTDAP---AVCG--VDLAVRSGQTVAVVGES
Rv3663c|M.tuberculosis_H37Rv -MSVPAAPLLSVEGLEVTFGTDAP---AVCG--VDLAVRSGQTVAVVGES
MMAR_5151|M.marinum_M -MSTAAAPLLSVHGLQVRFGTDEP---VVAG--MDLSVYRGQTVAVVGES
MUL_4237|M.ulcerans_Agy99 -MSTAAAPLLSVHGLQVRFGTDEP---VVAG--MDLSVYRGQTVAVVGES
MAV_3418|M.avium_104 ----MGPPLLDVSGLTVTYPGAVP---RVALDRVDLAVSSGEFVAVVGES
MLBr_02352|M.leprae_Br4923 --MRNNDKAVMVRGVRKTYGKGKI----IALDDVSFDVDRGEVIGLLGPN
: : .: : :.: : : .::* .
MSMEG_1711|M.smegmatis_MC2_155 GAGKSTLIKALTGVYD----IDDGTIVVAG----TPCTFAGPRQAQEAGI
Mvan_5292|M.vanbaalenii_PYR-1 GAGKSTLVKAIAGIHP----IDTGTYLFEG----KPVTVHSPNDVSALGV
Mflv_2758|M.gilvum_PYR-GCK GSGKTMTVLAATGLLDAPGARVSGVSTLGGEVHLVGATPKALRSVHGARI
TH_4070|M.thermoresistible__bu GSGKSMTVLAAAGLLDAPGAVVTGSATVGG-VELIGAPPRLLRSVHGNRV
MAB_0429|M.abscessus_ATCC_1997 GSGKSTTAMAIPALLP-PSARVRGSVKLNG-AELLGATNDELRAVRGKDV
Mb3687c|M.bovis_AF2122/97 GSGKSTTAAAILGLLPAGGRITAGRVVFDG-RDITGADAKRLRSIRGREI
Rv3663c|M.tuberculosis_H37Rv GSGKSTTAAAILGLLPAGGRITAGRVVFDG-RDITGADAKRLRSIRGREI
MMAR_5151|M.marinum_M GSGKSTAAAAILGLLAPGGRITAGRIIFDG-RDITSADRRVMRTIRGREI
MUL_4237|M.ulcerans_Agy99 GSGKSTAAAAILGLLAPGGRITAGRIIFDG-RDITSADRRVMRTIRGREI
MAV_3418|M.avium_104 GSGKTTLANAVVGLLPAAARITAGSLTIAG-RDVLGLSERQWCRLRGSTV
MLBr_02352|M.leprae_Br4923 GAGKTTMVDILSTLTR----PDRGLATVAG-YDVVSEPAGVRRSIMVTGQ
*:**: : * . *
MSMEG_1711|M.smegmatis_MC2_155 STVYQEVNLCPNLTVGENILLGREPRRWGR-IDYRTLNRRARELLAELEL
Mvan_5292|M.vanbaalenii_PYR-1 EVVYQDLALCDNLDIVENMFLGRELKRRGM-LDEARMETMAREALTSLSV
Mflv_2758|M.gilvum_PYR-GCK GFVFQDPGTSLNPLLTLERQITESLETHRN-LTRRAANDRALELLEAVGL
TH_4070|M.thermoresistible__bu GFVFQDPGTSLNPLLTLERQITEVLEAHRG-MTRRAARGRALELLTAVGL
MAB_0429|M.abscessus_ATCC_1997 AVIFQEPMTALNPVYTIGWQIAEAVCAHKK-MSRRQARDRAVELLDLVDM
Mb3687c|M.bovis_AF2122/97 GYVPQDPMTNLNPVWKVGFQVTEALRANTD---GRAARRRAVELLAEAGL
Rv3663c|M.tuberculosis_H37Rv GYVPQDPMTNLNPVWKVGFQVTEALRANTD---GRAARRRAVELLAEAGL
MMAR_5151|M.marinum_M GYVPQDPMTNLNPVWKVGFQIREALRANTD---GRDARRRTVELLAQAGM
MUL_4237|M.ulcerans_Agy99 GYVPQDPMTNLNPVWKVGFQIREALRANTD---GRDARRRTVELLAQAGM
MAV_3418|M.avium_104 GLVPQDPATSLNPVRSIGSQIAEIFPLKGERLSRREARRRCIELLDRVEI
MLBr_02352|M.leprae_Br4923 QVAVDDQLSGEQNLILFGRLYG---------LSKSVARVRTQELLEQFDL
:: : . * * :
MSMEG_1711|M.smegmatis_MC2_155 D-IDP--RSQLGSHPIAIQQLVAIARATAVRAQVLILDEPTSSLDAREVG
Mvan_5292|M.vanbaalenii_PYR-1 R-TVKSVRQPVSSLSGGQRQTVAIAKSVLWNSKVVLLDEPTAALGVAQTR
Mflv_2758|M.gilvum_PYR-GCK PEPQMRLHAYPHQLSGGQRQRVMIAIALACDPELLIADEPTTALDVTTQA
TH_4070|M.thermoresistible__bu PDPAARLRSYPHQLSGGQRQRVMIAIALACDPEVLIADEPTTALDVTTQA
MAB_0429|M.abscessus_ATCC_1997 PEPAKRVKHYPHQLSGGQRQRAMIAQALALDPGLLIADEPTTALDVTVQA
Mb3687c|M.bovis_AF2122/97 PDPAKQAGRYPHQLSGGMCQRALIAIGLAGRPRLLIADEPTSALDVTVQR
Rv3663c|M.tuberculosis_H37Rv PDPAKQAGRYPHQLSGGMCQRALIAIGLAGRPRLLIADEPTSALDVTVQR
MMAR_5151|M.marinum_M PDPDKHAQRYPHQLSGGMCQRALIAIGLAGRPALLIADEPTSALDVTVQR
MUL_4237|M.ulcerans_Agy99 PDPDKHAQRYPHQLSGGMCQRALIAIGLAGRPALLIADEPTSALDVTVQR
MAV_3418|M.avium_104 DRPAQRLKQYPGELSGGMRQRVLIAIAFALNPGLLIADEPTSALDVTVQR
MLBr_02352|M.leprae_Br4923 LHAGK---RRVGTYSGGMRRRIDIACGLVVQPQVAFLDEPTTGLDPRSRQ
. . : ** . . : : ****:.*.
MSMEG_1711|M.smegmatis_MC2_155 ELFRVIRRLR-DSGTAILFVSHFLDQIYAISDRMTVLRNGKLVGEYLTAE
Mvan_5292|M.vanbaalenii_PYR-1 QVIELVRGLA-ERGVGVVLISHNMNDVFEVADRICALYLGRVAAEVKASE
Mflv_2758|M.gilvum_PYR-GCK QIIELVRTLQRDFGTAVVWISHDLGVIGQVADDVTVMRNGIAVEQAPIMA
TH_4070|M.thermoresistible__bu QIIELVRELQRDFGTAVVWISHDLGVIGEVADEVTVLRHGAAVEQAHIAE
MAB_0429|M.abscessus_ATCC_1997 EILDLMRDLRHRIDAGIILITHDMGVVADMADRIMVMKDGEVVEQGDAEG
Mb3687c|M.bovis_AF2122/97 QVLDHLQGLTDELGTALLLITHDLALAAQRAEAVVVVRRGVVVESGAAQS
Rv3663c|M.tuberculosis_H37Rv QVLDHLQGLTDELGTALLLITHDLALAAQRAEAVVVVRRGVVVESGAAQS
MMAR_5151|M.marinum_M QVLDHLQRRTDELGTALLLITHDLALAAERAESVLVVHHGVVVESGTASD
MUL_4237|M.ulcerans_Agy99 QVLDHLQRRTDEVGTALLLITHDLALAAERAESVLVVDHGVVVESGTASD
MAV_3418|M.avium_104 HVLAVFDRLVAEQRTTVVFITHDIGVATDHASRIVVMRGGVVVEDAPAEA
MLBr_02352|M.leprae_Br4923 AIWDLVASFK-QIGIATLLTTQYLEEADELSDRIILIDHGTVIAEGTASE
: . : :: : :. : : * .
MSMEG_1711|M.smegmatis_MC2_155 LPKSDLVAAMLGRQLDVLDEVAEAA-----------------------NV
Mvan_5292|M.vanbaalenii_PYR-1 VSHGQVVELIT---------------------------------------
Mflv_2758|M.gilvum_PYR-GCK VFDNPRDDYTRDLLAARPVLERAGP--------------GPVTDAETLLD
TH_4070|M.thermoresistible__bu VFERPRHPYTRELLHARPRLGVGGP--------------PQVTSTEVLLR
MAB_0429|M.abscessus_ATCC_1997 IFHRAQQPYTRQLLASVPHLGATLH--------------GRDESNPPPTD
Mb3687c|M.bovis_AF2122/97 ILQSPQHEYTRRLVAAAPSLTARSRRPPESR----SRATTQAG---DILV
Rv3663c|M.tuberculosis_H37Rv ILQSPQHEYTRRLVAAAPSLTARSRRPPESR----SRATTQAG---DILV
MMAR_5151|M.marinum_M ILRSPQHEYTKRLVAAAPSLTVRDPRRAPARGPVPGGADQPAGGCGDILS
MUL_4237|M.ulcerans_Agy99 ILRSPQHEYTKRLVAAAPSLTVRDPRRAPARGPVPGGADQPAGGCGDILS
MAV_3418|M.avium_104 IVAAPRTEYAAHLVR---RLTAPAP------------AAAPAG-SEDVIE
MLBr_02352|M.leprae_Br4923 LKHRVGETFCEIVPR-------------------------------DLKD
:
MSMEG_1711|M.smegmatis_MC2_155 TAETAEHQSETLVRADALGRVPAVHPVTLDIGRGEILGLAGLLGSGRTEL
Mvan_5292|M.vanbaalenii_PYR-1 -----------AGRSGSLGLAPAQAAESM---------------------
Mflv_2758|M.gilvum_PYR-GCK VDGLDVSFAVSSPV-GRS-TVHAVKDVSFRIRRGTTLGLVGESGSGKSTV
TH_4070|M.thermoresistible__bu VEGLQVRYDVSTPT-GRS-TVRAVSDLSLSIRRGTTLGLVGESGSGKSTV
MAB_0429|M.abscessus_ATCC_1997 LA-LSVEHAVIEYP-GKSGSFRAVDDVSFTIGRGEVVGLVGESGSGKSTI
Mb3687c|M.bovis_AF2122/97 VSELTKIYRESRGAPWRRVESRAVDGVSFRLPRASTLAIVGESGSGKSTL
Rv3663c|M.tuberculosis_H37Rv VSELTKIYRESRGAPWRRVESRAVDGVSFRLPRASTLAIVGESGSGKSTL
MMAR_5151|M.marinum_M VSELTKIYRESRGAPWRRGEFRAVDSVSFRLRRASTLAIVGESGSGKSTV
MUL_4237|M.ulcerans_Agy99 VSELTKIYRESRGAPWRRGEFRAVDSVSFRLRRASTLAIVGESGSGKSTV
MAV_3418|M.avium_104 VAGVAKEFRLG-----ARARHTAVAEVAFTVRRGETLALVGESGSGKSTT
MLBr_02352|M.leprae_Br4923 LGTVVAALGSLLPERSRAMLTPTSDRITMPAPDGTQTLIEAARRIDEVSV
: ::
MSMEG_1711|M.smegmatis_MC2_155 ARLLFGADRATSGHVEIRGRRVALRTPRSAIAHGFAFTSENRKDEGVVGD
Mvan_5292|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2758|M.gilvum_PYR-GCK AAALTGLVTPDAGTATLAGD--DVFSVKGRAARDMRRRIGLVFQDPFASL
TH_4070|M.thermoresistible__bu AAALTGLVRPTAGRATLAGV--DLFGVRGRDRRRLRRRISLVFQDPFSSL
MAB_0429|M.abscessus_ATCC_1997 GRAAVGLLRVASGTICVAGQ--DISTANRKQLRDIRSKVGVVFQDPGSSL
Mb3687c|M.bovis_AF2122/97 ARMVLGLLQPTSGTVVFDGT-YDVGALARDQVLAFRRRVQPVFQNPYSSL
Rv3663c|M.tuberculosis_H37Rv ARMVLGLLQPTSGTVVFDGT-YDVGALARDQVLAFRRRVQPVFQNPYSSL
MMAR_5151|M.marinum_M ARMVLGLLQPTSGTVSFDGARIQPDKLDRDAQLAFRRRIQPVFQNPYSSL
MUL_4237|M.ulcerans_Agy99 ARMVLGLLQPTSGTVSFDGARIQPDKLDRDAQLAFRCRIQPVFQNPYSSL
MAV_3418|M.avium_104 AKMVVGLLTPTRGTVRVLGR--DVAALPARARRRHWQDIQFVYQNPGSAL
MLBr_02352|M.leprae_Br4923 ELADIALRRPSLDDVFLSMTTDPSESLSHLAAGAMR--------------
MSMEG_1711|M.smegmatis_MC2_155 LSVRENLVLALQARRGFARPLSTKTKDQLVAKYLDALDIRPRNPDTLLKN
Mvan_5292|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2758|M.gilvum_PYR-GCK NPRARVDTSIAEPLVVHKVVDGKDARHRRVGELLDLVGLPAEFAQRYPHE
TH_4070|M.thermoresistible__bu NPRMRVIDSISEPLRVHGLADGDRARCRRVADLLELVGLPADFGARYPHE
MAB_0429|M.abscessus_ATCC_1997 NPRWPIGQSIAEPLTLHTDMDR-TQREGRVKTLLEQVQLPAAMRNRFPHQ
Mb3687c|M.bovis_AF2122/97 DPMYSVFRAIEEPLRVHHVGDR-RQRQRAVRELVDQVALPSSILGRRPRE
Rv3663c|M.tuberculosis_H37Rv DPMYSVFRAIEEPLRVHHVGDR-RQRQRAVRELVDQVALPSSILGRRPRE
MMAR_5151|M.marinum_M DPMYSVFRAIEEPLRIHRVGDR-AQRRQMVAELVDQVALPSSVLGRLPRE
MUL_4237|M.ulcerans_Agy99 DPMYSVFRAIEEPLRIHRVGDR-GQRRQMVAELVDQVALPSSVLGRLPRE
MAV_3418|M.avium_104 DPRWTVRQILDGPLRSYRVDDR-ARRAQRIAEALASVGLSDDKLDRRPGE
MLBr_02352|M.leprae_Br4923 --------------------------------------------------
MSMEG_1711|M.smegmatis_MC2_155 LSGGNQQKVLLARWLITEPDLFILDEPTRGIDVGAKTQIQKLVTELAGDG
Mvan_5292|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2758|M.gilvum_PYR-GCK LSGGQRQRVSIARALAAEPDLLILDEATASLDVSVQARVLELLSRLQSEL
TH_4070|M.thermoresistible__bu LSGGQRQRVSVARALATDPDLLILDESTASLDVSVQDRVLDLLADLQREL
MAB_0429|M.abscessus_ATCC_1997 LSGGQRQRVGIARALALEPTLLIADEPTSALDVSVQATVLDLFAELQREH
Mb3687c|M.bovis_AF2122/97 LSGGQRQRVAIARALALRPEVLVCDEAVSALDVLVQAQILDLLADLQADL
Rv3663c|M.tuberculosis_H37Rv LSGGQRQRVAIARALALRPEVLVCDEAVSALDVLVQAQILDLLADLQADL
MMAR_5151|M.marinum_M LSGGQRQRVAIARALALRPDVLVCDEAVSALDVLVQAQILDLLAELQADL
MUL_4237|M.ulcerans_Agy99 LSGGQRQRVAIARALALRPDVLVCDEAVSALDVLVQAQILDLLAELQADL
MAV_3418|M.avium_104 LSGGECQRVAIARALVLRPQIVVLDEPLSALDVVTQDQIVGLLLRLQRQL
MLBr_02352|M.leprae_Br4923 --------------------------------------------------
MSMEG_1711|M.smegmatis_MC2_155 -MAIVFISAELDEVTRISTRIAVMRDRHNVALAEAGTSPSKLTALIAGTS
Mvan_5292|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2758|M.gilvum_PYR-GCK ALTYLLIGHDLAVIRQLSHDVLVMRDGEAVENRPADDLFAHPEQQYTRDL
TH_4070|M.thermoresistible__bu GLTYLFIAHDLAVVERMSHDVLVLRAGETVEYRPAAELFAAPEHEYTRAL
MAB_0429|M.abscessus_ATCC_1997 GFACLFISHDLAVVELVASRIAVLNRGRLAEFGSDTQVLTAPKDDYTKRL
Mb3687c|M.bovis_AF2122/97 GLTYLFISHDLAVIRQIADDVLVMRAGRVVEHASTEEVFSRPRHEYTRQL
Rv3663c|M.tuberculosis_H37Rv GLTYLFISHDLAVIRQIADDVLVMRAGRVVEHASTEEVFSRPRHEYTRQL
MMAR_5151|M.marinum_M GLAYLFISHDLAVVRQISDDVLVMRAGQVVEHAPTEEVFTRPGAQYTQRL
MUL_4237|M.ulcerans_Agy99 GLAYLFISHDLAVVRQISDDVLVMRAGQVVEHAPTEEVFTRPGAQYTQRL
MAV_3418|M.avium_104 GLTYLFVSHDLSVVRRLAHRVVVLRAGRVVETGDTAAVFAAPAADYTRAL
MLBr_02352|M.leprae_Br4923 --------------------------------------------------
MSMEG_1711|M.smegmatis_MC2_155 ------------------------
Mvan_5292|M.vanbaalenii_PYR-1 ------------------------
Mflv_2758|M.gilvum_PYR-GCK LAAVPPRTP---------RAAV--
TH_4070|M.thermoresistible__bu LAAVPAVRP---------RAAG--
MAB_0429|M.abscessus_ATCC_1997 LAAVPVPDPEQQRIRREERQALR-
Mb3687c|M.bovis_AF2122/97 LQAIPGAPSAP-------RKVGNL
Rv3663c|M.tuberculosis_H37Rv LQAIPGAPSAP-------RKVGNL
MMAR_5151|M.marinum_M LEAIPGGPVAP-------R-----
MUL_4237|M.ulcerans_Agy99 LEAIPGGPVAP-------R-----
MAV_3418|M.avium_104 LDAVPGRRLAH-------PALSPS
MLBr_02352|M.leprae_Br4923 ------------------------