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MVEGDKRLGLTADEVLTTTRAVRKRLDYSRPVPRELVTECVRIATQAPSGRNRQRWDFVVVDDPRLRSRV AEIWRRGLFAGVPGTGGRHEVSRMTSPEEWRRIAAGLDHLAAHLHEAPMLLIPCVRVASRRELATVRGQA GAWGSVLPAVWSFMLAARERGLGTAWTTCHLSYELEMAELLGIDADHVVQAALTPVAFTRGTEFRPGPRA DHRDFLHWNTWDGRSRAGRKTG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1511 | - | - | 100% (232) | putative oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_1635 | - | 4e-45 | 43.32% (217) | nitroreductase family protein |
| M. smegmatis MC2 155 | MSMEG_6627 | - | 7e-15 | 33.80% (213) | nitroreductase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3403c | - | 1e-46 | 42.59% (216) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_4892 | - | 3e-53 | 49.54% (216) | nitroreductase |
| M. tuberculosis H37Rv | Rv3368c | - | 1e-46 | 42.59% (216) | oxidoreductase |
| M. leprae Br4923 | MLBr_00418 | - | 2e-45 | 42.99% (214) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_3693c | - | 8e-51 | 46.76% (216) | oxidoreductase |
| M. marinum M | MMAR_1160 | - | 2e-46 | 43.12% (218) | nitroreductase |
| M. avium 104 | MAV_4334 | - | 1e-47 | 44.91% (216) | nitroreductase family protein |
| M. thermoresistible (build 8) | TH_2121 | - | 6e-50 | 46.30% (216) | POSSIBLE OXIDOREDUCTASE |
| M. ulcerans Agy99 | MUL_2854 | - | 2e-46 | 42.66% (218) | nitroreductase |
| M. vanbaalenii PYR-1 | Mvan_1532 | - | 2e-50 | 46.36% (220) | nitroreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3403c|M.bovis_AF2122/97 -----MTLNLSVDEVLTTTRSVRKRLDFDKPVPRDVLMECLELALQAPTG
Rv3368c|M.tuberculosis_H37Rv -----MTLNLSVDEVLTTTRSVRKRLDFDKPVPRDVLMECLELALQAPTG
MMAR_1160|M.marinum_M -----MTLNLSVDEVLTTTRSVRKRLDFDKPVSREVLMECLDLALQAPTG
MUL_2854|M.ulcerans_Agy99 -----MTLNLSVDEVLTTTRSVRKRLDFDKPVSREVLMECLDLALQAPTG
MLBr_00418|M.leprae_Br4923 ---------MSVDEVLTTTRSVRKRLDFDKPVPRDVLMECLQLALQAPTG
MAV_4334|M.avium_104 -----MTLNLSVDEVLTTTRSVRKRLDFDKPVPREVLMECLELALQAPTG
TH_2121|M.thermoresistible__bu -----MALNLSVDDVLTTTRSVRKRLDLEKPVPREVLMECLELALQAPTG
Mflv_4892|M.gilvum_PYR-GCK -----MTLNLSADEVLTTTRSVRKRLDFDRPVPREVLNECLEIALQAPTG
Mvan_1532|M.vanbaalenii_PYR-1 -----MTLNLSADEVLTTTRSVRKRLDFDKPVPRDVLMECLDIALQAPTG
MAB_3693c|M.abscessus_ATCC_199 ----MTSLNLSADEVLTTTRSVRKRLDFDKPVERAVVEECLNIAMQAPTG
MSMEG_1511|M.smegmatis_MC2_155 MVEGDKRLGLTADEVLTTTRAVRKRLDYSRPVPRELVTECVRIATQAPSG
::.*:******:****** .:** * :: **: :* ***:*
Mb3403c|M.bovis_AF2122/97 SNSQGWQWVFVEDAAKKKAIADVYLANARGYLSGPAPEYPDGDTRG-ERM
Rv3368c|M.tuberculosis_H37Rv SNSQGWQWVFVEDAAKKKAIADVYLANARGYLSGPAPEYPDGDTRG-ERM
MMAR_1160|M.marinum_M SNSQGWQWVFVEDADKKKAIAEVYLARARSYLSMPAPEYAEGDTRG-ERM
MUL_2854|M.ulcerans_Agy99 SNSQGWQWVFVEDADKKKAIADVYLARARSYLSMPAPEYAEGDTRG-ERM
MLBr_00418|M.leprae_Br4923 SNSQGWHWVFVEDAEKRKAIGDIYLVNARCYLSQPAPEYPEGDTRG-ERM
MAV_4334|M.avium_104 SNAQGWQWVFVEDADKKKAIADIYLANARAYLSLPAAEYPEGDTRG-ERM
TH_2121|M.thermoresistible__bu SNAQGWQWVFVEDPDTKKALADIYRVNADAYLDRPRPSY--DDVRG-ERM
Mflv_4892|M.gilvum_PYR-GCK SNAQGWQFVFVDDPEKKKALADIYRIAADPYLEAEKPTF--GDVRD-ERT
Mvan_1532|M.vanbaalenii_PYR-1 SNNQGWQWVFVEDPEKKKAIADIYRTNATPYLAMEKPAT--GDMRD-GQR
MAB_3693c|M.abscessus_ATCC_199 SNHQGWHWVIVEDAEKKKAIADIYREGWNKYAKGAGATYAEGDTRA-ERK
MSMEG_1511|M.smegmatis_MC2_155 RNRQRWDFVVVDDPRLRSRVAEIWRRGLFAGVPGTGGRHEVSRMTSPEEW
* * *.:*.*:*. :. :.::: . .
Mb3403c|M.bovis_AF2122/97 GRVRDSATYLAEHMHRAPVLLIPCLK--GREDESAVG-GVSFWASLFPAV
Rv3368c|M.tuberculosis_H37Rv GRVRDSATYLAEHMHRAPVLLIPCLK--GREDESAVG-GVSFWASLFPAV
MMAR_1160|M.marinum_M GKVRDSATYLAEHMHEAPVLMIPCIQ--GREDKSPLG-GVSFWASLFPAV
MUL_2854|M.ulcerans_Agy99 GKVRDSATYLAEHMHEAPVLMIPCIQ--GREDKSPLG-GVSLWASLFPAV
MLBr_00418|M.leprae_Br4923 RLVRDSATYLAEHMHEVPVLLIPCLL--GRAEESPLG-AVSYWASLFPAV
MAV_4334|M.avium_104 PKVKDSAVYLAEHMHEAPVLLIPCLE--GRVENAPLGLSASFWASLFPAA
TH_2121|M.thermoresistible__bu DRVKSSARYLSEHFHEVPVLLVPCLE--GRPDNQPAGVTASFWGSLLPAV
Mflv_4892|M.gilvum_PYR-GCK PLVVDSAKYLAEHLHEAPVMLIPCLE--GRPDGAPAGMSAGFWGSLLPAV
Mvan_1532|M.vanbaalenii_PYR-1 PRVEDSARYLNEHLEKVPVMLIPCLQ--GKPQDAVSGASAGYWGSLLPAV
MAB_3693c|M.abscessus_ATCC_199 AKVVDSAGYLAENFERSPLFLIPCIE--GRLDNLPVVGAASSWGSLLPAV
MSMEG_1511|M.smegmatis_MC2_155 RRIAAGLDHLAAHLHEAPMLLIPCVRVASRRELATVRGQAGAWGSVLPAV
: . :* ::.. *::::**: .: : .. *.*::**.
Mb3403c|M.bovis_AF2122/97 WSFCLALRSRGLGSCWTTLHLLDNGEHKVADVLGIPYDEYSQGGLLPIAY
Rv3368c|M.tuberculosis_H37Rv WSFCLALRSRGLGSCWTTLHLLDNGEHKVADVLGIPYDEYSQGGLLPIAY
MMAR_1160|M.marinum_M WSFCLALRSRGLGSCWTTLHLLADGERQVADVLGIPYDDYSQGGLFPIAY
MUL_2854|M.ulcerans_Agy99 WSFCLALRSRGLGSCWTTLHLLADGERQVADVLGIPYDDYSQGGLFPIAY
MLBr_00418|M.leprae_Br4923 WSFCLALRSRGLGTCWTSLHLLGDGEQRAAEVLGIPSDKYSQGGLFPIAY
MAV_4334|M.avium_104 WSFCLALRSRGLGTCWTTLHLINDGEKQAAELLGIPHDRYSQGGLFPIAY
TH_2121|M.thermoresistible__bu WSFMLALRSRGLGSAWTTLHLVGDGEQRAAEVLGIPFDRYSQAGLFPIAY
Mflv_4892|M.gilvum_PYR-GCK WSFMLALRSRGLGSAWTTLHLIGDGEKQAAEVLGIPFDKYSQGGLFPIAY
Mvan_1532|M.vanbaalenii_PYR-1 WSFMLALRSRGLGSAWTTLHLLGDGERQAAEILGIPFDNYSQAGLFPIAY
MAB_3693c|M.abscessus_ATCC_199 WSFMLAARNRGLGSAWTTLHLMDDGEKRTADIVGIPFDKVTQGGLFPIAY
MSMEG_1511|M.smegmatis_MC2_155 WSFMLAARERGLGTAWTTCHLS--YELEMAELLGIDADHVVQAALTPVAF
*** ** *.****:.**: ** * . *:::** * *..* *:*:
Mb3403c|M.bovis_AF2122/97 TQGIDFRPAKRLPAESVTHWNGW-----------
Rv3368c|M.tuberculosis_H37Rv TQGIDFRPAKRLPAESVTHWNGW-----------
MMAR_1160|M.marinum_M TKGTDFRPAKRLPADRLTHWNSW-----------
MUL_2854|M.ulcerans_Agy99 TKGTDFRPAKRLPADRLTHWNSW-----------
MLBr_00418|M.leprae_Br4923 TKGTDFRPANRLPAENVTHWDIW-----------
MAV_4334|M.avium_104 TKGTDFRPAKRLPAEQVTHWDSW-----------
TH_2121|M.thermoresistible__bu TKGTDFRPAKRLPAEQVVHWNRW-----------
Mflv_4892|M.gilvum_PYR-GCK TKGTDFKKAKRLPAEQLTHWNTW-----------
Mvan_1532|M.vanbaalenii_PYR-1 TKGTDFRRAKRLPAEQLTHWDTW-----------
MAB_3693c|M.abscessus_ATCC_199 TVGTDFRLAKRQPLADVLHWDTW-----------
MSMEG_1511|M.smegmatis_MC2_155 TRGTEFRPGPRADHRDFLHWNTWDGRSRAGRKTG
* * :*: . * . **: *