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MTTSIDAVATSESIKATYRRYLSSLLAVRDPKIDVALRKAIDGTNLLDKGPYLEATPPYAPGKPLRDLIA EGVLAPSFAELASDALPLDRPLYVHQEQSIRKVAAGRNIVVATGTGSGKTESFLLPILDSLVREREQGGL GPGVRALLLYPMNALANDQMKRLRRVLVTYPDITFGRYTGETPHDPRTAREQFAELNIDEPLLPNEILSR QEMRERPPHLLLTNYAMLEYLLLRPLDMELFDTGSESKWRFIVVDEAHVYDGTQGAEIAMLLRRVRDRVA PGRPIQCIATSATVGSDSDPTAVTRFASNIFGQEFEWHKEDSARQDVIMARRVTAPPGPFWGPLSSADYC ALADAPDSEAAVIEAARRAGWEAARGTSTTAASALSHEQSLAVMRRTLAAGPQTFDRVAAATFGSAPEAA DGLAAMVELASTLREADGTTPLSARYHLFLRATEGAFTCLSSRGPHVHLARHLICPDCDAPAFEIGSCKR CGAVHIYGTPTQENGSLYLRPRKAGGRGTWFVLGDHDGLTDEDEAAAVDDGDEVSGDGARLCTYCGALGD DDASTCGACASSELRPVRKLRQRGEEIAGCLVCGARGAGTVRMFETGPDATGAVITTALYQKIPPANDSH GATTPGEGRKLLAFSDSRQAAAYFAPYLEESYSRLQRRRLISQGMLAAHADEEPAGIEDIVFKTRSKAAG VKHFPGRMTAQQQTRVVAPWVMAEVLATDDRQSLEGLGLVSISLHRESRWQAPRPLLDIGLTDVEAWAFL QELVRTLRQQGAVTMPEDVPPNDQIFAPRLGPIRARLSGPESIRKVLSWLPGRGTNRRVDYTRRVLQALQ CEVDAEQLLKGVWEFLVRRETPVDWLKSSTESGLGQVYQVDHECLRLRWVSDEWPVYQCRICRRTAPFSV RGVCPALGCDGVLERFVPPPLDRDRDHYRALYRMMNAVPLTVKEHTAQWVTTEAAAIQHEFVRGEVNTLS CSTTFELGVDVGELQAVMLRNMPPSTANYLQRAGRAGRRSGAAALVVTYATRKSHDLTRFNEPEVMMSGQ VRAPYVPLTNTRIDRRHAHSVALSAFFRWHFETTGRIDRKAGAFFLDQDGNEASVQLVKSFLQPVPADIT ESLARVFPPDVVVELDLAGGAWADHLIKLLEDVRTELARDVETMKELEHKASAEGKHGLAARYQKVGQTL RERDLLGYLANRNVLPKYGFPVDSVELRTDFGTGKVKGSKLDLTRDLSQAIYEYAPGAEIVAGGGLWVSR GIYRLPGRDLLEYRYHVCKRCGGFRYGLEAVEEKCQHCGEVAATAPRTLTVPEFGFVSAPEPGKPGPRPP RRSWSGAVHILEQPPDARTYTKVVAGGKLHVSAGPRGRLVALADGPNRMGFWVCDWCGHGSPRLSNPQKP PKHDHLLKNHPCPGTQKLLDLGHVYETDLLSIDANVFGARAGQAAWLSVMYAIVEAASEKLEIAREDIGG SLTPVGAERWAITLFDAVPGGAGHVLQVEQNLEQVLQCALKRVSECECGPETSCYGCLRSYQNQRDHDHL SRGAAQRVLRQLLVQSDGTDAVDGGLRIDEVPESLPEDWEEVYRSAFGQERQIIQTLAYAGAARPELGFE AANGVPIPIAWPDRLVAADYGLEATDRTDLVAEGWTVLSMDALVQRSSPVVEQQAVP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1254 | - | - | 100% (1667) | DEAD/DEAH box helicase |
| M. smegmatis MC2 155 | MSMEG_6160 | - | 6e-14 | 28.11% (338) | ATP-dependent rna helicase, dead/deah box family protein |
| M. smegmatis MC2 155 | MSMEG_1757 | - | 1e-08 | 30.32% (221) | DEAD/DEAH box helicase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3673 | - | 5e-16 | 27.73% (339) | putative helicase |
| M. gilvum PYR-GCK | Mflv_1391 | - | 9e-16 | 28.49% (337) | DEAD/DEAH box helicase domain-containing protein |
| M. tuberculosis H37Rv | Rv3649 | - | 7e-15 | 27.73% (339) | helicase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0486c | - | 2e-13 | 24.52% (420) | DEAD-box ATP dependent DNA helicase |
| M. marinum M | MMAR_5141 | - | 3e-14 | 26.20% (374) | DEAD/DEAH box helicase |
| M. avium 104 | MAV_4267 | - | 3e-14 | 32.44% (225) | DEAD/DEAH box helicase |
| M. thermoresistible (build 8) | TH_0854 | - | 5e-13 | 26.76% (340) | PROBABLE HELICASE |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_5399 | - | 2e-14 | 28.20% (344) | DEAD/DEAH box helicase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1391|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5399|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0854|M.thermoresistible__bu --------------------------------------------------
Mb3673|M.bovis_AF2122/97 --------------------------------------------------
Rv3649|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5141|M.marinum_M --------------------------------------------------
MAB_0486c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_1254|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4267|M.avium_104 MSTRAEPRPSDPLGRFSAITREWFTSTFAAPTTAQAQAWSAIADGHNTLV
Mflv_1391|M.gilvum_PYR-GCK --------------------------MTEPVPEFGRELLACAVEGTAADE
Mvan_5399|M.vanbaalenii_PYR-1 --------------------------MTDPGPDFGRELLACAVDGTAAGE
TH_0854|M.thermoresistible__bu --------------------------VEETGPNFGRELLACAVAGTAPDE
Mb3673|M.bovis_AF2122/97 ------------------------------MASFGSHLLAAAVAGTPPGE
Rv3649|M.tuberculosis_H37Rv ------------------------------MASFGSHLLAAAVAGTPPGE
MMAR_5141|M.marinum_M ------------------------------MISFGRELLAVALAGTPTGE
MAB_0486c|M.abscessus_ATCC_199 -----------------------------MTVGYGRELLDLIVAGTPSGE
MSMEG_1254|M.smegmatis_MC2_155 ----------------MTTSIDAVATSESIKATYRRYLSSLLAVRDPKID
MAV_4267|M.avium_104 IAPTGSGKTLAAFLWALDSLAGQAERAPGTRVLYVSPLKALAVDVERNLR
: *
Mflv_1391|M.gilvum_PYR-GCK HPLR---HVAD---LPPRRATSHPWPPWADPDVVQAFHDQG----IRSL-
Mvan_5399|M.vanbaalenii_PYR-1 YPLR---HVAD---LPPRRARAQAWPHWADPDVVRAFHDRG----VEAL-
TH_0854|M.thermoresistible__bu RPVR---HIAD---VPPRRGRTRPWPSWADPDVVRVFGDRG----ITEP-
Mb3673|M.bovis_AF2122/97 RPLR---HVAE---LPPQAGRPRGWPEWAEPDVVDAFADRG----ISSP-
Rv3649|M.tuberculosis_H37Rv RPLR---HVAE---LPPQAGRPRGWPEWAEPDVVDAFADRG----ISSP-
MMAR_5141|M.marinum_M HPLH---HVAE---LPPRAGQPSAWPQWAEPDVVRTFTQRG----ITAP-
MAB_0486c|M.abscessus_ATCC_199 TPVR---HICD---IPARNAEVTSWPQWAHPDAIAAFAAQG----VTAP-
MSMEG_1254|M.smegmatis_MC2_155 VALR---KAIDGTNLLDKGPYLEATPPYAPGKPLRDLIAEG----VLAPS
MAV_4267|M.avium_104 TPLAGLTRIAERAGLPAPDISVGVRSGDTPPAVRRQLINRPPDVLITTP-
.: : : : . : : . :
Mflv_1391|M.gilvum_PYR-GCK ---------------WSHQLAAADLAHDGRHVVLS------TGTASGKSL
Mvan_5399|M.vanbaalenii_PYR-1 ---------------WSHQLAAAELARDGRHVVLS------TGTASGKSL
TH_0854|M.thermoresistible__bu ---------------WEHQAVAADLAHSGRHVVLS------TGTASGKSL
Mb3673|M.bovis_AF2122/97 ---------------WSHQAEAAELAYAGRHVVIG------TGPASGKSL
Rv3649|M.tuberculosis_H37Rv ---------------WSHQAEAAELAYAGRHVVIG------TGPASGKSL
MMAR_5141|M.marinum_M ---------------WSHQSTAAELAHDGRHVVVS------TGTASGKSL
MAB_0486c|M.abscessus_ATCC_199 ---------------WSHQVAAATLAFAGRHVVVA------TGTASGKSV
MSMEG_1254|M.smegmatis_MC2_155 FAELASDALPLDRPLYVHQEQSIRKVAAGRNIVVA------TGTGSGKTE
MAV_4267|M.avium_104 ------------ESLFLMLTSAARETLAGVQTVIVDEIHAIAGGKRGAHL
: : . * : *: :* *
Mflv_1391|M.gilvum_PYR-GCK AYQLPIATELKRN-------PRSRVLYLSPTKALGHDQLRAAAALTASVP
Mvan_5399|M.vanbaalenii_PYR-1 AYQLPILTALKEN-------PRSRALYLSPTKALGHDQLRAAAALTAAVP
TH_0854|M.thermoresistible__bu AYQLPILSALAAD-------PRARVLYLSPTKALGHDQLRAAQELTGAVE
Mb3673|M.bovis_AF2122/97 AYQLPVLNALATD-------SRARALYLSPTKALGHDQLRAAHALAAAVP
Rv3649|M.tuberculosis_H37Rv AYQLLVLNALATD-------SRARALYLSPTKALGHDQLRAAHALAAAVP
MMAR_5141|M.marinum_M AYQLPVLAALAAD-------PRARVLYLSPTKALGHDQLRTAQALVANVE
MAB_0486c|M.abscessus_ATCC_199 AYQLPILTALASE-------PRARALYLAPTKALGHDQLRAVRELITGVD
MSMEG_1254|M.smegmatis_MC2_155 SFLLPILDSLVREREQGGLGPGVRALLLYPMNALANDQMKRLRRVLVTYP
MAV_4267|M.avium_104 ALSLERLDALREG-------RPAQRIGLSATVRPPDELARFLSGAAPGTR
: * * : : * . .: :
Mflv_1391|M.gilvum_PYR-GCK GLDDVAPTPYDGDSPSEVRR--FARERSRWIFSNPDMIHLSLLRNHAR--
Mvan_5399|M.vanbaalenii_PYR-1 GLADVAPTPYDGDSPTEVRR--FARERSRWIFSNPDMIHLSMLRNHAR--
TH_0854|M.thermoresistible__bu RLATVAPTAYDGDSPTEVRR--FARERSRWIFSNPDMVHLAMLRNHGR--
Mb3673|M.bovis_AF2122/97 RLADVAPTAYDGDSPDEVRR--FARERSRWLFSNPEMTHLSVLRNHAR--
Rv3649|M.tuberculosis_H37Rv RLADVAPTAYDGDSPDEVRR--FARERSRWLFSNPEMTHLSVLRNHAR--
MMAR_5141|M.marinum_M RLRDVAPTAYDGDSSDEVRR--FARERSRWLFSNPDMIHLSILRNHAR--
MAB_0486c|M.abscessus_ATCC_199 NFERVQPCTYDGDSSNELRR--FARESSRWIFTNPDMIHVSLLHNHTR--
MSMEG_1254|M.smegmatis_MC2_155 ---DITFGRYTGETPHDPRT--AREQFAELNIDEPLLPNEILSRQEMRER
MAV_4267|M.avium_104 TTVVAPPSAKTVELSVQVPVPDMANLANNTIWPDVENRLVDLIEAHGS--
: . : . . : : . .
Mflv_1391|M.gilvum_PYR-GCK ------------WAVFLR-------------NLRYVVVDECHYYRGIFGS
Mvan_5399|M.vanbaalenii_PYR-1 ------------WAVFLR-------------HLQYLVIDECHYYRGIFGS
TH_0854|M.thermoresistible__bu ------------WAVFLR-------------HLRYVVVDECHYYRGIFGS
Mb3673|M.bovis_AF2122/97 ------------WAVLLR-------------NLRFVIVDECHYYRGVFGS
Rv3649|M.tuberculosis_H37Rv ------------WAVLLR-------------NLRFVIVDECHYYRGVFGS
MMAR_5141|M.marinum_M ------------WAVLLR-------------NLRYLIVDECHYYRGVFGS
MAB_0486c|M.abscessus_ATCC_199 ------------WSAFLR-------------GLRYLVVDECHYYRGVFGS
MSMEG_1254|M.smegmatis_MC2_155 PPHLLLTNYAMLEYLLLRPLDMELFDTGSESKWRFIVVDEAHVYDGTQGA
MAV_4267|M.avium_104 ---------TIVFANSRRLAERLTARLNEIHAERSGVELSATANPKVAGG
* : : .. *.
Mflv_1391|M.gilvum_PYR-GCK NVAMVLRRLLR---------------------------------LCARYA
Mvan_5399|M.vanbaalenii_PYR-1 NVAMVLRRLLR---------------------------------LCARYS
TH_0854|M.thermoresistible__bu NVAMVLRRLLR---------------------------------LCQRYS
Mb3673|M.bovis_AF2122/97 NVAMVLRRLLR---------------------------------LCARYS
Rv3649|M.tuberculosis_H37Rv NVAMVLRRLLR---------------------------------LCARYS
MMAR_5141|M.marinum_M NVAMVLRRLLR---------------------------------LCARYS
MAB_0486c|M.abscessus_ATCC_199 NVALILQRLLR---------------------------------LCERYG
MSMEG_1254|M.smegmatis_MC2_155 EIAMLLRRVRDRVAPGRPIQCIATSATVGSDSDPTAVTRFASNIFGQEFE
MAV_4267|M.avium_104 APAHIMASGQTYGVEPILARAHHGSVSKEQRALVEEDLKRGLLKAVVATS
* ::
Mflv_1391|M.gilvum_PYR-GCK PAG-DVSGPTVVFASATTAQPA----------------------------
Mvan_5399|M.vanbaalenii_PYR-1 ATGADFSGPTVIFASATTAQPA----------------------------
TH_0854|M.thermoresistible__bu AGG----SPTVFFASATTAAPA----------------------------
Mb3673|M.bovis_AF2122/97 AHP------TVIFASATTASPG----------------------------
Rv3649|M.tuberculosis_H37Rv AHP------TVIFASATTASPG----------------------------
MMAR_5141|M.marinum_M AHP------TVIFASATTDSPG----------------------------
MAB_0486c|M.abscessus_ATCC_199 SHP------TVVFASATTANPG----------------------------
MSMEG_1254|M.smegmatis_MC2_155 WHKEDSARQDVIMARRVTAPPGPFWGPLSSADYCALADAPDSEAAVIEAA
MAV_4267|M.avium_104 SLELGIDMGAVDLVIQVEAPPSVASG------------------------
* :. . *.
Mflv_1391|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5399|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0854|M.thermoresistible__bu --------------------------------------------------
Mb3673|M.bovis_AF2122/97 --------------------------------------------------
Rv3649|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5141|M.marinum_M --------------------------------------------------
MAB_0486c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_1254|M.smegmatis_MC2_155 RRAGWEAARGTSTTAASALSHEQSLAVMRRTLAAGPQTFDRVAAATFGSA
MAV_4267|M.avium_104 --------------------------------------------------
Mflv_1391|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5399|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0854|M.thermoresistible__bu --------------------------------------------------
Mb3673|M.bovis_AF2122/97 --------------------------------------------------
Rv3649|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5141|M.marinum_M --------------------------------------------------
MAB_0486c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_1254|M.smegmatis_MC2_155 PEAADGLAAMVELASTLREADGTTPLSARYHLFLRATEGAFTCLSSRGPH
MAV_4267|M.avium_104 --------------------------------------------------
Mflv_1391|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5399|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0854|M.thermoresistible__bu --------------------------------------------------
Mb3673|M.bovis_AF2122/97 --------------------------------------------------
Rv3649|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5141|M.marinum_M --------------------------------------------------
MAB_0486c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_1254|M.smegmatis_MC2_155 VHLARHLICPDCDAPAFEIGSCKRCGAVHIYGTPTQENGSLYLRPRKAGG
MAV_4267|M.avium_104 ---LQRIGRAGHQVGEVSRGVLFPKHRTDLIGCAVTVQRMLAGQIETMRV
Mflv_1391|M.gilvum_PYR-GCK -------ITASELIGQTVAEVTEDGS------------------------
Mvan_5399|M.vanbaalenii_PYR-1 -------ATASELIGQTVAEVTEDGS------------------------
TH_0854|M.thermoresistible__bu -------DTASELIGQSVTEVTDDAS------------------------
Mb3673|M.bovis_AF2122/97 -------ATAADLIGQPVVEVTEDGS------------------------
Rv3649|M.tuberculosis_H37Rv -------ATAADLIGQPVVEVTEDGS------------------------
MMAR_5141|M.marinum_M -------ATAAELIGQPVAEVTEDGS------------------------
MAB_0486c|M.abscessus_ATCC_199 -------AAAQALIGQPVEEVVADGS------------------------
MSMEG_1254|M.smegmatis_MC2_155 RGTWFVLGDHDGLTDEDEAAAVDDGDEVSGDGARLCTYCGALGDDDASTC
MAV_4267|M.avium_104 PANPLDILAQQTVAAAALEPLDADRWFDTVRRAAPFATLPRSIYEATLDL
: *
Mflv_1391|M.gilvum_PYR-GCK ----------------------------PQGARTIALWEP------ALIP
Mvan_5399|M.vanbaalenii_PYR-1 ----------------------------PQGARTVALWEP------ALIA
TH_0854|M.thermoresistible__bu ----------------------------PHGARTIALWEP------PLLP
Mb3673|M.bovis_AF2122/97 ----------------------------PRGARTVALWEP------ALRS
Rv3649|M.tuberculosis_H37Rv ----------------------------PRGARTVALWEP------ALRS
MMAR_5141|M.marinum_M ----------------------------PQGARTVALWEP------ALRT
MAB_0486c|M.abscessus_ATCC_199 ----------------------------PHGMRTVALWEP------PLLP
MSMEG_1254|M.smegmatis_MC2_155 GACASSELRPVRKLRQRGEEIAGCLVCGARGAGTVRMFETGPDATGAVIT
MAV_4267|M.avium_104 LSGKYPSTEFAELRPRLVYDRNTGTLTARPGAQRLAVTSGGAIPDRGLFT
* : : . : .
Mflv_1391|M.gilvum_PYR-GCK DLLGENGAPVRRSAGAEAAR------------------------------
Mvan_5399|M.vanbaalenii_PYR-1 DLVGENGAPVRRSAGAEASR------------------------------
TH_0854|M.thermoresistible__bu DLVGENGAPVRRPAGAEAAR------------------------------
Mb3673|M.bovis_AF2122/97 DVIGEHGAPVRRSAGAEAAR------------------------------
Rv3649|M.tuberculosis_H37Rv DVIGEHGAPVRRSAGAEAAR------------------------------
MMAR_5141|M.marinum_M DLTGENGAPVRRSAGTEAAR------------------------------
MAB_0486c|M.abscessus_ATCC_199 -ITGENGAPVRRPVSTETSR------------------------------
MSMEG_1254|M.smegmatis_MC2_155 TALYQKIPPANDSHGATTPGEGRKLLAFSDSRQAAAYFAPYLEESYSRLQ
MAV_4267|M.avium_104 VYLASEAEKPSRVGELEEEMVYES--------------------------
..
Mflv_1391|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5399|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0854|M.thermoresistible__bu --------------------------------------------------
Mb3673|M.bovis_AF2122/97 --------------------------------------------------
Rv3649|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5141|M.marinum_M --------------------------------------------------
MAB_0486c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_1254|M.smegmatis_MC2_155 RRRLISQGMLAAHADEEPAGIEDIVFKTRSKAAGVKHFPGRMTAQQQTRV
MAV_4267|M.avium_104 --------------------------------------------------
Mflv_1391|M.gilvum_PYR-GCK ----VMADLIAEG-------------------------------------
Mvan_5399|M.vanbaalenii_PYR-1 ----VMADLIAEG-------------------------------------
TH_0854|M.thermoresistible__bu ----VMADLVAEG-------------------------------------
Mb3673|M.bovis_AF2122/97 ----VMADLIVEG-------------------------------------
Rv3649|M.tuberculosis_H37Rv ----VMADLIVEG-------------------------------------
MMAR_5141|M.marinum_M ----VMADLIVEG-------------------------------------
MAB_0486c|M.abscessus_ATCC_199 ----LLADLVQEG-------------------------------------
MSMEG_1254|M.smegmatis_MC2_155 VAPWVMAEVLATDDRQSLEGLGLVSISLHRESRWQAPRPLLDIGLTDVEA
MAV_4267|M.avium_104 ----RPGDVISLG-------------------------------------
.::: .
Mflv_1391|M.gilvum_PYR-GCK -----------------------------------------------ART
Mvan_5399|M.vanbaalenii_PYR-1 -----------------------------------------------ART
TH_0854|M.thermoresistible__bu -----------------------------------------------ART
Mb3673|M.bovis_AF2122/97 -----------------------------------------------AQT
Rv3649|M.tuberculosis_H37Rv -----------------------------------------------AQT
MMAR_5141|M.marinum_M -----------------------------------------------AQT
MAB_0486c|M.abscessus_ATCC_199 -----------------------------------------------ART
MSMEG_1254|M.smegmatis_MC2_155 WAFLQELVRTLRQQGAVTMPEDVPPNDQIFAPRLGPIRARLSGPESIRKV
MAV_4267|M.avium_104 -------------------------ATSWRITEITHDRVLVIPAPGQPAR
Mflv_1391|M.gilvum_PYR-GCK LTFVRSRRG-----------------------------------------
Mvan_5399|M.vanbaalenii_PYR-1 LTFVRSRRG-----------------------------------------
TH_0854|M.thermoresistible__bu LTFVRSRRG-----------------------------------------
Mb3673|M.bovis_AF2122/97 LTFVRSRRA-----------------------------------------
Rv3649|M.tuberculosis_H37Rv LTFVRSRRA-----------------------------------------
MMAR_5141|M.marinum_M LTFVRSRRA-----------------------------------------
MAB_0486c|M.abscessus_ATCC_199 LAFVRSRRG-----------------------------------------
MSMEG_1254|M.smegmatis_MC2_155 LSWLPGRGTNRRVDYTRRVLQALQCEVDAEQLLKGVWEFLVRRETPVDWL
MAV_4267|M.avium_104 LPFWRGDGVGRPAELGAALGAFTGELAGLSREEFDSRCAALGFDAYAVDN
*.: .
Mflv_1391|M.gilvum_PYR-GCK ---------------------------------------------AELAA
Mvan_5399|M.vanbaalenii_PYR-1 ---------------------------------------------AELAA
TH_0854|M.thermoresistible__bu ---------------------------------------------AELTA
Mb3673|M.bovis_AF2122/97 ---------------------------------------------AELTA
Rv3649|M.tuberculosis_H37Rv ---------------------------------------------AELTA
MMAR_5141|M.marinum_M ---------------------------------------------AELTA
MAB_0486c|M.abscessus_ATCC_199 ---------------------------------------------AEMTA
MSMEG_1254|M.smegmatis_MC2_155 KSSTESGLGQVYQVDHECLRLRWVSDEWPVYQCRICRRTAPFSVRGVCPA
MAV_4267|M.avium_104 LYGLFDEQRTAAGVVPTDTTLLVERFRDELGDWRVILHSPYGLGVNGPLA
*
Mflv_1391|M.gilvum_PYR-GCK LGARTRLADTAP------------------DLADQVASYRAGYLAEDRRR
Mvan_5399|M.vanbaalenii_PYR-1 LGARARLADTAP------------------ELAQQVASYRAGYLAEDRRA
TH_0854|M.thermoresistible__bu LGARSRLEEIAP------------------ELAQRVASYRAGYLAEDRRA
Mb3673|M.bovis_AF2122/97 LGARARLVDIAP------------------ELSDTVASYRAGYLAEDRSA
Rv3649|M.tuberculosis_H37Rv LGARARLVDIAP------------------ELSDTVASYRAGYLAEDRSA
MMAR_5141|M.marinum_M LGAQARLQDIAP------------------QLSHTVASYRAGYLPEDRNC
MAB_0486c|M.abscessus_ATCC_199 LGAAHRLSEVDP------------------GLVSQVAAYRAGYLPEDRRA
MSMEG_1254|M.smegmatis_MC2_155 LGCDGVLERFVPPPLDRDRDHYRALYRMMNAVPLTVKEHTAQWVTTEAAA
MAV_4267|M.avium_104 LAVGRRLRERYG----IDEKPTASDDGVVVRLPDTVSDFASDGGDTPPGA
*. * : * . :
Mflv_1391|M.gilvum_PYR-GCK LERALADGELRGMATTNA-----LELGVDIAGLDAVVLAG-FPGTVASFW
Mvan_5399|M.vanbaalenii_PYR-1 LERALAEGELRGVATTNA-----LELGMDIAGLDAVVLAG-FPGTVASFW
TH_0854|M.thermoresistible__bu LEQALANGELRALATTNA-----LELGIDIAGLDAVVLAG-FPGTVTSFW
Mb3673|M.bovis_AF2122/97 LHQALAEGQLRGLATTNA-----LELGVDIAGLDAVVLAG-FPGTVASFW
Rv3649|M.tuberculosis_H37Rv LHQALAEGQLRGLATTNA-----LELGVDIAGLDAVVLAG-FPGTVASFW
MMAR_5141|M.marinum_M LEHALTEGRLRGLATTNA-----LELGVDIAGLDAVVLAG-FPGTVASFW
MAB_0486c|M.abscessus_ATCC_199 LEQALSSGTLTGAATTNA-----LELGVDIAGLDAVVVAG-FPGTVASFW
MSMEG_1254|M.smegmatis_MC2_155 IQHEFVRGEVNTLSCSTT-----FELGVDVGELQAVMLRN-MPPSTANYL
MAV_4267|M.avium_104 ELFVFDADEIDPIVTAEVGGSALFASRFRECAARALLLPRRHPGRRSPLW
: . : : . : . *::: * :
Mflv_1391|M.gilvum_PYR-GCK QQAGRA------GRR-GQGALVVLIARDDPLDTYLVHHPAALLD----KP
Mvan_5399|M.vanbaalenii_PYR-1 QQAGRA------GRR-GQGALIVLIARDDPLDTYLVHHPAALLD----KP
TH_0854|M.thermoresistible__bu QQAGRS------GRR-GQSALIVLIARDDPLDTYLVHHPSALLD----RP
Mb3673|M.bovis_AF2122/97 QQAGRS------GRR-GQGALVVLIARDDPLDTYLVHHPAALLD----KP
Rv3649|M.tuberculosis_H37Rv QQAGRS------GRR-GQGALVVLIARDDPLDTYLVHHPAALLD----KP
MMAR_5141|M.marinum_M QQAGRS------GRR-GQGALVVLIARDDPLDTYLVHHPAALLD----KP
MAB_0486c|M.abscessus_ATCC_199 QQAGRS------GRR-GQGSLVVLVARDDPLDTYLVHHPEALLD----KP
MSMEG_1254|M.smegmatis_MC2_155 QRAGRA------GRRSGAAALVVTYATRKSHDLTRFNEPEVMMS----GQ
MAV_4267|M.avium_104 QQRQRAAQLLEVARKYPDFPVVLETVRECLQDVYDVPALVALMAGIAQRR
*: *: .*: .::: . * . .::
Mflv_1391|M.gilvum_PYR-GCK IERVVIDPANPYVLG-----------------------------------
Mvan_5399|M.vanbaalenii_PYR-1 IERVVIDPANPYVLG-----------------------------------
TH_0854|M.thermoresistible__bu IERVVIDPTNPHVLG-----------------------------------
Mb3673|M.bovis_AF2122/97 VERVVIDPVNPHLLG-----------------------------------
Rv3649|M.tuberculosis_H37Rv VERVVIDPVNPHLLG-----------------------------------
MMAR_5141|M.marinum_M VERVVIDPGNPYLLG-----------------------------------
MAB_0486c|M.abscessus_ATCC_199 IEAVVIDPTNPHVLR-----------------------------------
MSMEG_1254|M.smegmatis_MC2_155 VRAPYVPLTNTRIDRRHAHSVALSAFFRWHFETTGRIDRKAGAFFLDQDG
MAV_4267|M.avium_104 VRVLEVETQRPSPFAASLLFGYVGAFMYEGDSPLAERRAAALSLDSTLLA
:. : ..
Mflv_1391|M.gilvum_PYR-GCK -------PQLLCAATELPLTEAEVRMWDAESVAAGLVDDGLLRRRPSGFF
Mvan_5399|M.vanbaalenii_PYR-1 -------PQLLCAATELPLTDAEVRMWGAEPVAESLVDDGLLRRRPSGFF
TH_0854|M.thermoresistible__bu -------PQLLCAAAELPLTIEEVRRWDAEEVAESLVDDGLLRRRASGYF
Mb3673|M.bovis_AF2122/97 -------PQLLCAATELPLDDAEVRSWGAVEVAESLVDDGLLRRRNGRYF
Rv3649|M.tuberculosis_H37Rv -------PQLLCAATELPLDDAEVRSWGAVEVAESLVDDGLLRRRNGRYF
MMAR_5141|M.marinum_M -------PQLLCAATELPLDAVEVHELRAVEVVEALVDDGLLRRRGDKYF
MAB_0486c|M.abscessus_ATCC_199 -------PHLLCAATELPLTEDDVRSLDAGQVVSDLVDDGLLRKRPGGYF
MSMEG_1254|M.smegmatis_MC2_155 NEASVQLVKSFLQPVPADITESLARVFPPDVVVELDLAGGAWADHLIKLL
MAV_4267|M.avium_104 ELLGRVELRELLDPEVVAATARALQHLAPERAARDAEAVADLLRLLGPLT
: : . : . .. .
Mflv_1391|M.gilvum_PYR-GCK P------APGLDPHPAVDIRGSTGG-------------------------
Mvan_5399|M.vanbaalenii_PYR-1 P------APGLDPHPAVDIRGSTGG-------------------------
TH_0854|M.thermoresistible__bu P------SPGVDPHPAVDIRAAAGG-------------------------
Mb3673|M.bovis_AF2122/97 P------APGVKPHAAVDVRGAIGG-------------------------
Rv3649|M.tuberculosis_H37Rv P------APGVKPHAAVDVRGAIGG-------------------------
MMAR_5141|M.marinum_M P------APGVQPHAAVDIRGSIGG-------------------------
MAB_0486c|M.abscessus_ATCC_199 A------APGLNPYAAVDIRGSIGG-------------------------
MSMEG_1254|M.smegmatis_MC2_155 EDVRTELARDVETMKELEHKASAEGKHGLAARYQKVGQTLRERDLLGYLA
MAV_4267|M.avium_104 EDEVVARAGGADAVEVRGWLEGLRAARRAVPVSFAGRSWWVAIEDIGRLR
: . .. . .
Mflv_1391|M.gilvum_PYR-GCK --------------QIAILEDGTGRMLG-----STGAGQAPASVHPGAVY
Mvan_5399|M.vanbaalenii_PYR-1 --------------QIAILEAGTGRMLG-----SAGAGQAPASVHPGAVY
TH_0854|M.thermoresistible__bu --------------QIAIVETGTGRLLG-----SAGVGQAPASVHPGAVY
Mb3673|M.bovis_AF2122/97 --------------QIVIVEAGTGRLLG-----SVGVGQAPAAAHPGAVY
Rv3649|M.tuberculosis_H37Rv --------------QIVIVEAGTGRLLG-----SVGVGQAPAAAHPGAVY
MMAR_5141|M.marinum_M --------------QVVIVEADTGRLLG-----NVGADQAPASVHPGAVY
MAB_0486c|M.abscessus_ATCC_199 --------------QVMILEADTGRVLG-----TVDTGRAPATVHPGAVY
MSMEG_1254|M.smegmatis_MC2_155 NRNVLPKYGFPVDSVELRTDFGTGKVKGSKLDLTRDLSQAIYEYAPGAEI
MAV_4267|M.avium_104 DGLGIAVPLGVPAAFTEEVADPLGELLG-----RYARTHTPFSTAEAAAR
*.: * :: .*
Mflv_1391|M.gilvum_PYR-GCK LHQGESYVVDSLDFEDG---------------------------------
Mvan_5399|M.vanbaalenii_PYR-1 LHQGESYVVDSLDFEDA---------------------------------
TH_0854|M.thermoresistible__bu LHQGESYLVDSLNFEEG---------------------------------
Mb3673|M.bovis_AF2122/97 LHQGETYVVDSLDFQDG---------------------------------
Rv3649|M.tuberculosis_H37Rv LHQGETYVVDSLDFQDG---------------------------------
MMAR_5141|M.marinum_M LHQGESYVVDSLDTEEG---------------------------------
MAB_0486c|M.abscessus_ATCC_199 LHSGETYVVDSLDFGDG---------------------------------
MSMEG_1254|M.smegmatis_MC2_155 VAGGGLWVSRGIYRLPGRDLLEYRYHVCKRCGGFRYGLEAVEEKCQHCGE
MAV_4267|M.avium_104 FGLGLRVTADVLGRLADPSTSQGRLVRG----------------------
. * :
Mflv_1391|M.gilvum_PYR-GCK -------------IAFVHAEDPG-------------------YTTFAREV
Mvan_5399|M.vanbaalenii_PYR-1 -------------VAFVHAEDPG-------------------YTTFAREL
TH_0854|M.thermoresistible__bu -------------VAFVHAEDPG-------------------YTTSAREI
Mb3673|M.bovis_AF2122/97 -------------IAFVHAEDPG-------------------YATFAREV
Rv3649|M.tuberculosis_H37Rv -------------IAFVHAEDPG-------------------YATFAREV
MMAR_5141|M.marinum_M -------------LAFVHAADPG-------------------YATFAREL
MAB_0486c|M.abscessus_ATCC_199 -------------IALVHNDRPD-------------------YSTFARST
MSMEG_1254|M.smegmatis_MC2_155 VAATAPRTLTVPEFGFVSAPEPGKPGPRPPRRSWSGAVHILEQPPDARTY
MAV_4267|M.avium_104 ------------DFVAARPSEPGGVLGAEQWCDADVLRILRRRSLAALRA
. . *. . *
Mflv_1391|M.gilvum_PYR-GCK TDISVTG-----AGER-----SGHGPVTVGLVPVSVTNTVTGYLR-RRLD
Mvan_5399|M.vanbaalenii_PYR-1 TDINVTG-----AGER-----AGYGPVTVGLVPVSVSNTVTGYLR-RRMD
TH_0854|M.thermoresistible__bu TDISVTG-----VGER-----KTFGPVTIGLVPVSVTNTVTGYLR-REMS
Mb3673|M.bovis_AF2122/97 TDIAVTG-----TGER-----LVFGPVALGLVPVTVTNHVVGYLR-RQLS
Rv3649|M.tuberculosis_H37Rv TDIAVTG-----TGER-----LVFGPVALGLVPVTVTNHVVGYLR-RQLS
MMAR_5141|M.marinum_M TDIAVTG-----SGER-----LEFGPVTVGLVPVTVTHQVVGYLR-RRLS
MAB_0486c|M.abscessus_ATCC_199 IDIAITG-----EGER-----IDLGDIQIGLVPVDVTHQVIGYLR-TLTT
MSMEG_1254|M.smegmatis_MC2_155 TKVVAGGKLHVSAGPRGRLVALADGPNRMGFWVCDWCGHGSPRLS-NPQK
MAV_4267|M.avium_104 QVEPVSTAAYGRFLPAWHRVGAAESSRAPGHSGLDGLMSVIEQLAGVRLP
. * *
Mflv_1391|M.gilvum_PYR-GCK GEVIDFIELDMPTRTLNTMAAMCTITPEALQDAGIDPLRIPG---ALHAA
Mvan_5399|M.vanbaalenii_PYR-1 GEVIDFVELDMPTRSLETMAVMCTITPEALQDNGIDPLRLPG---SLHAA
TH_0854|M.thermoresistible__bu GEVIDFVELDMPSRTLDTMAVMCTITPEALADNDIDPVRIPG---SLHAA
Mb3673|M.bovis_AF2122/97 GEVLDFVELDMPEHTLPTTAVMYTITSDALVRSGIEATRIPG---SLHAA
Rv3649|M.tuberculosis_H37Rv GEVLDFVELDMPEHTLPTTAVMYTITSDALVRSGIEATRIPG---SLHAA
MMAR_5141|M.marinum_M GEVIDFVELDMPEHVLPTTAVMYTITAEELLRNGVDAVAIPG---SLHAA
MAB_0486c|M.abscessus_ATCC_199 GEILDFVELDMPSSTLSTKAVMYTVTPEALAGIDIDPLSTPG---ALHAA
MSMEG_1254|M.smegmatis_MC2_155 PPKHDHLLKNHPCPGTQKLLDLGHVYETDLLSIDANVFGARAGQAAWLSV
MAV_4267|M.avium_104 ASALEPLVLAPRVRDYSPALLDELLATGEVTWSGAGSISGSDGWIALHPS
: : : : . : .
Mflv_1391|M.gilvum_PYR-GCK EHAAIGLLP-----------------------------------------
Mvan_5399|M.vanbaalenii_PYR-1 EHAAIGLLP-----------------------------------------
TH_0854|M.thermoresistible__bu EHAAIGLLP-----------------------------------------
Mb3673|M.bovis_AF2122/97 EHAAIGLLP-----------------------------------------
Rv3649|M.tuberculosis_H37Rv EHAAIGLLP-----------------------------------------
MMAR_5141|M.marinum_M EHAAIGLLP-----------------------------------------
MAB_0486c|M.abscessus_ATCC_199 EHAAIGLLP-----------------------------------------
MSMEG_1254|M.smegmatis_MC2_155 MYAIVEAAS-----------------------------------------
MAV_4267|M.avium_104 ESAPLTLQGPADIELGEAHRAILDVLAGGGGYFFRQLATDGVSDAELKAA
* :
Mflv_1391|M.gilvum_PYR-GCK ------------LMASCDRGDIGG--------------------------
Mvan_5399|M.vanbaalenii_PYR-1 ------------LMASCDRGDIGG--------------------------
TH_0854|M.thermoresistible__bu ------------LVASCDRGDIGG--------------------------
Mb3673|M.bovis_AF2122/97 ------------LVASCDRGDIGG--------------------------
Rv3649|M.tuberculosis_H37Rv ------------LVASCDRGDIGG--------------------------
MMAR_5141|M.marinum_M ------------LVASCDRGDIGG--------------------------
MAB_0486c|M.abscessus_ATCC_199 ------------LVASCDRGDIGG--------------------------
MSMEG_1254|M.smegmatis_MC2_155 ------------EKLEIAREDIGG--------------------------
MAV_4267|M.avium_104 LWELVWAGWITGDTFAPVRALLGGGGTRRRSAPAHRAQRPPRLSRYSVAH
* :**
Mflv_1391|M.gilvum_PYR-GCK ---------------VSTAVGPVDGLPTIFVYDGYPGGAGFAARGFRTLA
Mvan_5399|M.vanbaalenii_PYR-1 ---------------VSTAVGPVDGLPTIFVYDGYPGGAGFAARGFRTMD
TH_0854|M.thermoresistible__bu ---------------VSTAVGPDSGLPTIFVYDGYPGGAGFADRGFDQFE
Mb3673|M.bovis_AF2122/97 ---------------MSTATGP-EGLPSVFVYDGYPGGAGFAERGFRRAR
Rv3649|M.tuberculosis_H37Rv ---------------MSTATGP-EGLPSVFVYDGYPGGAGFAERGFRRAR
MMAR_5141|M.marinum_M ---------------ISTAIGP-EGLPSVFVYDGYPGGAGFAERGFRRAR
MAB_0486c|M.abscessus_ATCC_199 ---------------VSTALQPETGLPTVFVYDGHPGGAGFAARGYHKLA
MSMEG_1254|M.smegmatis_MC2_155 ---------------SLTPVGA--ERWAITLFDAVPGGAGHVLQVEQNLE
MAV_4267|M.avium_104 PQARPADTTVAGRWSVLPPPEPDSTVRAHFQAELLLGRHGVLTRGAVAAE
.. . : : * * :
Mflv_1391|M.gilvum_PYR-GCK RWWE---------ATASAIEACECP--SGCPSCVQSPKCGNGNDPLDKDG
Mvan_5399|M.vanbaalenii_PYR-1 RWWE---------ATASAIEACECP--SGCPSCVQSPKCGNGNDPLDKDG
TH_0854|M.thermoresistible__bu TWWG---------ATADAIESCECP--AGCPSCVQSPKCGNGNDPLDKAG
Mb3673|M.bovis_AF2122/97 TWLG---------ATAEAIEACECP--SGCPSCVQSPKCGNGNDPLDKAG
Rv3649|M.tuberculosis_H37Rv TWLG---------ATAEAIEACECP--SGCPSCVQSPKCGNGNDPLDKAG
MMAR_5141|M.marinum_M TWLG---------ATASAIEACECP--SGCPSCVQSPKCGNGNDPLDKAG
MAB_0486c|M.abscessus_ATCC_199 TWLG---------ATADAIDACECD--AGCPSCVQSPKCGNGNSPLDKRA
MSMEG_1254|M.smegmatis_MC2_155 QVLQ---------CALKRVSECECGPETSCYGCLRSYQNQRDHDHLSRGA
MAV_4267|M.avium_104 GVAGGFATLYKVLSTFEDAGRCQRGYFIESLGGAQFAVASTVDRLRGFAD
.: . *: . . : . .
Mflv_1391|M.gilvum_PYR-GCK AIRVLR-----LVIGALEHRHR----------------------------
Mvan_5399|M.vanbaalenii_PYR-1 AILVLR-----MVVRLLTGRTD----------------------------
TH_0854|M.thermoresistible__bu AVRVLR-----LVLDELEKGNT----------------------------
Mb3673|M.bovis_AF2122/97 AVRVLR-----LVLAELSEESP----------------------------
Rv3649|M.tuberculosis_H37Rv AVRVLR-----LVLAELSEESP----------------------------
MMAR_5141|M.marinum_M AMQVLR-----LVLSQVGDDLL----------------------------
MAB_0486c|M.abscessus_ATCC_199 AVKVLR-----LVLSRLPG-------------------------------
MSMEG_1254|M.smegmatis_MC2_155 AQRVLR-----QLLVQSDGTDAVDGGLRIDEVPESLPEDWEEVYRSAFGQ
MAV_4267|M.avium_104 GVDPQRPEYRAIVLAAADPANPYGAALPWPASSADGARPGRKAGALVVLV
. * ::
Mflv_1391|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5399|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0854|M.thermoresistible__bu --------------------------------------------------
Mb3673|M.bovis_AF2122/97 --------------------------------------------------
Rv3649|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5141|M.marinum_M --------------------------------------------------
MAB_0486c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_1254|M.smegmatis_MC2_155 ERQIIQTLAYAGAARPELGFEAANGVPIPIAWPDRLVAADYGLEATDRTD
MAV_4267|M.avium_104 DGELAWFLERGGRSLLTFTDDPAAQHAAAAALAGLVSARRVAAILVERID
Mflv_1391|M.gilvum_PYR-GCK ------------------------------------
Mvan_5399|M.vanbaalenii_PYR-1 ------------------------------------
TH_0854|M.thermoresistible__bu ------------------------------------
Mb3673|M.bovis_AF2122/97 ------------------------------------
Rv3649|M.tuberculosis_H37Rv ------------------------------------
MMAR_5141|M.marinum_M ------------------------------------
MAB_0486c|M.abscessus_ATCC_199 ------------------------------------
MSMEG_1254|M.smegmatis_MC2_155 LVAEGWTVLSMDALVQRSSPVVEQQAVP--------
MAV_4267|M.avium_104 GVPALAPRGDGAAGNDALTALADAGFARTPRGMRLR