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VRVTGDRDAVARKRRHIDVCLNEAVDHQSVSTGLERYRLPYHALTQTNLTEIDLTTNFLGKPLRAPVLIG AMTGGAELSGTINRNLAAAAQKLGVGMMLGSQRIMLRSGEQAAHRSESFAVRDVAPDVLLVGNIGLSQLT HDNAPLITDALRRVGADALAVHTNPLQEAIQANGDTDFAGSRERLLEIGPSIGCPLLLKEVGHGIGAAAV AELTGGRDDVPVAAIDVAGAGGTSWSRVEQFVRYGTVRYPDLADWGVPTARAIIEVRQALPRIPLVASGG IRTGMDAAKGLFALDGVETISCFRAVIEGSGWLGVCRRRSGRARGRAECPGAVWTWRCCRS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1057 | fni | - | 100% (341) | isopentenyl pyrophosphate isomerase |
| M. smegmatis MC2 155 | MSMEG_2337 | fni | 0.0 | 100.00% (341) | isopentenyl pyrophosphate isomerase |
| M. smegmatis MC2 155 | MSMEG_6699 | - | 9e-29 | 86.36% (66) | hypothetical protein MSMEG_6699 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4187 | - | 1e-105 | 65.88% (296) | isopentenyl pyrophosphate isomerase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3242 | - | 5e-87 | 61.57% (268) | isopentenyl pyrophosphate isomerase |
| M. marinum M | MMAR_4812 | idi2 | 1e-108 | 70.67% (283) | isopentenyl pyrophosphate isomerase type 2 Idi2 |
| M. avium 104 | MAV_3894 | fni | 1e-114 | 74.47% (282) | isopentenyl pyrophosphate isomerase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0380 | idi2 | 1e-108 | 70.32% (283) | isopentenyl pyrophosphate isomerase |
| M. vanbaalenii PYR-1 | Mvan_2176 | - | 1e-108 | 71.07% (280) | isopentenyl pyrophosphate isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4812|M.marinum_M MTNDPA-EISSRKRRHIDVCLNDEVNYVGVTTGLERYRLPFNALTQTSLA
MUL_0380|M.ulcerans_Agy99 MTNDPA-EISSRKRRHIDVCLNDEVNYVGVTTGLERYRLPFNALTQTSLA
MAV_3894|M.avium_104 MD-----AMTHRKRRHIDVCLSDPVEFDGVTTGLDRYRLPYHALTQTSLG
Mflv_4187|M.gilvum_PYR-GCK MTPDPASALQHRKRRHIDVCLTDPVDYQTLTTGFERYQLPYNALTQTDLH
Mvan_2176|M.vanbaalenii_PYR-1 MTSDPGSALQHRKRRHIDVCLTEAVDYQSLTTGFERYRLPYNALTQTDLH
MAB_3242|M.abscessus_ATCC_1997 ------------------------MQYVTRTTGLERLDLPYMALPNSSLA
MSMEG_1057|M.smegmatis_MC2_155 MRVTGDRDAVARKRRHIDVCLNEAVDHQSVSTGLERYRLPYHALTQTNLT
::. :**::* **: **.::.*
MMAR_4812|M.marinum_M DIDLSAEFFGAPLRAPVLIGAMTGGAELSATINRNLATAAQRLGIGMMLG
MUL_0380|M.ulcerans_Agy99 DIDLSAEFFGAPLRAPVLIGAMTGGAELSAMINRNLATAAQRLGIGMMLG
MAV_3894|M.avium_104 DIDVSTSFFGANLRAPILIGAMTGGAEMSKTINRNLAAAAQQLGIGMMLG
Mflv_4187|M.gilvum_PYR-GCK SVDLGTEFMGSRLRAPVLIGAMTGGAALSGIINRNLAEAAQQLGVGMMLG
Mvan_2176|M.vanbaalenii_PYR-1 SVDLSTEFLGSHLRAPVLIGAMTGGAALSGIINRNLAAAAQQLGIGMMLG
MAB_3242|M.abscessus_ATCC_1997 GVDLSTEFLGRRLAAPVLIGAMTGGAKLAATINRNLAAAAQELGIGMMLG
MSMEG_1057|M.smegmatis_MC2_155 EIDLTTNFLGKPLRAPVLIGAMTGGAELSGTINRNLAAAAQKLGVGMMLG
:*: :.*:* * **:********* :: ****** ***.**:*****
MMAR_4812|M.marinum_M SQRIMLD-DARGQRAASSFAVREVAPDVLLIGNIGLAQLTKAAVPAVAAA
MUL_0380|M.ulcerans_Agy99 SQRIMLD-DARGQRAASSFAVREVAPDVLLIGNIGLAQLTKAAVPAVAAA
MAV_3894|M.avium_104 SQRIMLD-SALGERAADSFAVRDVAPDVLLFGNIGLSQLAKTAVPHLVKA
Mflv_4187|M.gilvum_PYR-GCK SQRVMID-DAV---AAESFDVRGVAPDVLVIGNIGLAQLQPSMVPALAAA
Mvan_2176|M.vanbaalenii_PYR-1 SQRVMID-DEA---AAASFEVRGVAPDILLIGNIGLAQLRSSMVPGLAAA
MAB_3242|M.abscessus_ATCC_1997 SQRVMLV-EPD---SADTFAVREVAPDILLIGNIGLAQLGNIAPAAQLNS
MSMEG_1057|M.smegmatis_MC2_155 SQRIMLRSGEQAAHRSESFAVRDVAPDVLLVGNIGLSQLTHDNAPLITDA
***:*: : :* ** ****:*:.*****:** . :
MMAR_4812|M.marinum_M LRR-VGANALAVHANSLQEAMQHGGDTDFSGSLGRLRDAADLLDYPVLLK
MUL_0380|M.ulcerans_Agy99 LRR-VGANALAVHANSLQEAMQHGGDTDFSGSLGRLRDAADLLDYPVLLK
MAV_3894|M.avium_104 LDR-VGADALAVHTNPLQEAMQHNGDTDFSGSLSRLREAAAALDYPVLLK
Mflv_4187|M.gilvum_PYR-GCK LDR-VGANGLAVHTNPLQEAMQHNGDTDFSGSMSRLREVVDSLGYPVMLK
Mvan_2176|M.vanbaalenii_PYR-1 LDR-VGANGLAVHTNPLQEAMQHDGDTDFSGSIGRLCDVAGAIGYPVVLK
MAB_3242|M.abscessus_ATCC_1997 LVRRVGADALAVHTNPLQEAVQPGGDTDFTGQVYRLAELTHAVEFPVLLK
MSMEG_1057|M.smegmatis_MC2_155 LRR-VGADALAVHTNPLQEAIQANGDTDFAGSRERLLEIGPSIGCPLLLK
* * ***:.****:*.****:* .*****:*. ** : : *::**
MMAR_4812|M.marinum_M EVGHGIGAAAVAQLLRLPGGLPVSGIDVAGAGGTSWSRVEQLVRYGELRY
MUL_0380|M.ulcerans_Agy99 EVGHGIGAAAVAQLLRLPGGLPVSGIDVAGAGGTSWSRVEQLVRYGELRY
MAV_3894|M.avium_104 EVGHGIGGAAAAELVGGEGQPPVAGIDVAGAGGTSWSRVEQFVRYGELRY
Mflv_4187|M.gilvum_PYR-GCK EVGHGIGASAAAQLVD----CPVAAVDVAGAGGTSWARIEQFVRYGEVRY
Mvan_2176|M.vanbaalenii_PYR-1 EVGHGIGAAAAAELVG----CPIAAIDVAGAGGTSWARIEQFVRYGDVRY
MAB_3242|M.abscessus_ATCC_1997 EVGHGISGAAARRLGG----CRLAAIDVAGAGGTSWARVEQFVRFGAITS
MSMEG_1057|M.smegmatis_MC2_155 EVGHGIGAAAVAELTGGRDDVPVAAIDVAGAGGTSWSRVEQFVRYGTVRY
******..:*. .* ::.:**********:*:**:**:* :
MMAR_4812|M.marinum_M PELADWGIPTAEAIVEVRQALPAVPLVASGGIRTGMDAAKAIALGADVVA
MUL_0380|M.ulcerans_Agy99 PELADWGIPTAEAIVEVRQALPAVPLVASGGIRTGMDAAKSIALGADVVA
MAV_3894|M.avium_104 PDLADWGVPTARAIVEVRRLLPEIPLVASGGIRTGMDAAKAIALGADVVA
Mflv_4187|M.gilvum_PYR-GCK PALAEWGIPTAQALTEVRGILPDVPLVASGGIRTGMDAAKALAMGAEVVA
Mvan_2176|M.vanbaalenii_PYR-1 PALAEWGVPTAQALTEVRQMLPDVPLVASGGIRTGMDAAKALAMGARVVA
MAB_3242|M.abscessus_ATCC_1997 PELAEWGIPTAEALVEVHAELPHMPLIGSGGIRTGMDAAKAIALGASVVS
MSMEG_1057|M.smegmatis_MC2_155 PDLADWGVPTARAIIEVRQALPRIPLVASGGIRTGMDAAKGLFALDGVET
* **:**:***.*: **: ** :**:.************.: * :
MMAR_4812|M.marinum_M IARPLLAPAIESATAVQGWLQLFLDELRVCLHCCGARDLTSLRDIGVTAI
MUL_0380|M.ulcerans_Agy99 IARPLLAPAIESATAVQDWLQLFLDELRVCLHCCGAPDLTSLRDIGVTAI
MAV_3894|M.avium_104 VARPLLPAAIESSAAVVDWLRPFIDELRVCLHGCGVADLAGLRAVELIRL
Mflv_4187|M.gilvum_PYR-GCK IARPLLAPAVESVGAVVDWLQRFIDELLVCLHGSGAANLSALRERGVTEL
Mvan_2176|M.vanbaalenii_PYR-1 VARPLLAPAVESVEAVVDWLQRFIDELLVCLHGCGAANLSALRGRGVTEL
MAB_3242|M.abscessus_ATCC_1997 VALPLLAPAVQSPQAVVAWLQQFLDELRIAMHCADVSTIADLRRISLRPR
MSMEG_1057|M.smegmatis_MC2_155 IS--CFRAVIEGS----GWLG-------VCRRRSGRARGRAECPGAVWTW
:: : ..::. ** :. : .. :
MMAR_4812|M.marinum_M R----
MUL_0380|M.ulcerans_Agy99 R----
MAV_3894|M.avium_104 A----
Mflv_4187|M.gilvum_PYR-GCK P----
Mvan_2176|M.vanbaalenii_PYR-1 P----
MAB_3242|M.abscessus_ATCC_1997 SSPR-
MSMEG_1057|M.smegmatis_MC2_155 RCCRS