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VLDVGSNTVHLLVVDAHRGGHPTPMSSTKAALRLAEAIDGSGKLTRKGADKLVATVDEFAKIATSSGCAE LMAFATSAVRDATNSEDVLARVRAETGVSLQVLSGVDESRLTFLAVRRWYGWSAGRIINIDIGGGSLELS NGVDEEPEVALSLPLGAGRLTREWLPDDPPGRRAVAMLRDWLATELADAGATIRRAGAPDLAVATSKTFR SLARLTGAAPSGAGPRVKRTLTATGLRQLIAFISRMTAADRAELEGVSAERAPQIVAGALVAEASMRALE IESVDICPWALREGLILRKLDSEADGTALVAAAARDAGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0939 | - | - | 100% (319) | Ppx/GppA phosphatase family protein |
| M. smegmatis MC2 155 | MSMEG_5413 | - | 1e-14 | 23.61% (288) | exopolyphosphatase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0507 | - | 1e-146 | 85.10% (302) | hypothetical protein Mb0507 |
| M. gilvum PYR-GCK | Mflv_0079 | - | 1e-154 | 87.86% (313) | Ppx/GppA phosphatase |
| M. tuberculosis H37Rv | Rv0496 | - | 1e-146 | 85.10% (302) | hypothetical protein Rv0496 |
| M. leprae Br4923 | MLBr_02434 | - | 1e-152 | 85.13% (316) | hypothetical protein MLBr_02434 |
| M. abscessus ATCC 19977 | MAB_4013c | - | 1e-148 | 85.48% (310) | hypothetical protein MAB_4013c |
| M. marinum M | MMAR_0822 | - | 1e-151 | 84.47% (322) | hypothetical protein MMAR_0822 |
| M. avium 104 | MAV_4656 | - | 1e-153 | 85.53% (318) | Ppx/GppA phosphatase family protein |
| M. thermoresistible (build 8) | TH_0881 | - | 1e-151 | 86.93% (306) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4566 | - | 1e-150 | 84.16% (322) | hypothetical protein MUL_4566 |
| M. vanbaalenii PYR-1 | Mvan_0833 | - | 1e-156 | 87.74% (318) | Ppx/GppA phosphatase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0822|M.marinum_M MRLGVLDVGSNTVHLLVVDAHRGGHPTPMSSTKATLRLAEATDSSGNITK
MUL_4566|M.ulcerans_Agy99 MRLGVLDVGSNTVHLLVVDAHRGGHPTPMSSTKATLRLAEATDSSGNITK
MLBr_02434|M.leprae_Br4923 MRLGVLDVGSNTVHLLVVDAYRGGHPTPMSSTKATLRMVEATDSSGKITK
Mb0507|M.bovis_AF2122/97 ----------------MVDAHRGGHPTPMSSTKATLRLAEATDSSGKITK
Rv0496|M.tuberculosis_H37Rv ----------------MVDAHRGGHPTPMSSTKATLRLAEATDSSGKITK
MAV_4656|M.avium_104 MRLGVLDVGSNTVHLLVVDAHRGGHPTPMSSTKATLRLAEATDSAGKITK
MAB_4013c|M.abscessus_ATCC_199 MRLGVLDVGSNTVHLLVVDARRGGHPTPMSSTKAALRLAEAIDESGKLTR
Mflv_0079|M.gilvum_PYR-GCK MRLGVLDVGSNTVHLLVVDARRGGHPTPMSSTKASLRLAEAIDDSGKLTR
Mvan_0833|M.vanbaalenii_PYR-1 MRLGVLDVGSNTVHLLVVDARRGGHPTPMSATKASLRLAESIDNSGKLTR
MSMEG_0939|M.smegmatis_MC2_155 ----MLDVGSNTVHLLVVDAHRGGHPTPMSSTKAALRLAEAIDGSGKLTR
TH_0881|M.thermoresistible__bu ----VLDVGSNTVHLLIVDARRGGHPTPMSSTKASLRLAEQIDGSGKITR
:*** *********:***:**:.* * :*::*:
MMAR_0822|M.marinum_M RGADKLVSTIDEFAKIAASSGCAELMAFATSAVREAENSDDVLSRVRNET
MUL_4566|M.ulcerans_Agy99 RGADKLVSTIDEFAKIAASSGCAELMAFATSAVREAENSDDVLSRVRNET
MLBr_02434|M.leprae_Br4923 RAADKLVSTIGEFAKIAVSSGCAELMAFATSAVREAGNSDDVLSRVRKET
Mb0507|M.bovis_AF2122/97 RGADKLISTIDEFAKIAISSGCAELMAFATSAVRDAENSEDVLSRVRKET
Rv0496|M.tuberculosis_H37Rv RGADKLISTIDEFAKIAISSGCAELMAFATSAVRDAENSEDVLSRVRKET
MAV_4656|M.avium_104 RGAEKLISTIDEFAKIADSSGCEELMAFATSAVREAGNSEEVLNRVRKET
MAB_4013c|M.abscessus_ATCC_199 KGADSLVHTIGEFSKIARSSGCTEIMAFATSAVRDATNSDEVLSRVKKET
Mflv_0079|M.gilvum_PYR-GCK RGADKLIGTLDEFARIATSSGCAELMAFATSAVRDARNSEEVLARVKAET
Mvan_0833|M.vanbaalenii_PYR-1 RGADKLVGTIDEFARIATSSGCAELMAFATSAVRDATNSEDVLARVRAET
MSMEG_0939|M.smegmatis_MC2_155 KGADKLVATVDEFAKIATSSGCAELMAFATSAVRDATNSEDVLARVRAET
TH_0881|M.thermoresistible__bu KGADKLISTIGEFARIAASSGCAELMAFATSAVRDATNTEEVLERVRAET
:.*:.*: *:.**::** **** *:*********:* *:::** **: **
MMAR_0822|M.marinum_M DVELQVLSGVDESRLTFLAVRRWFGWSAGRIINLDIGGGSLELSSGVDEE
MUL_4566|M.ulcerans_Agy99 GVELQVLSGVDESRLTFLAVRRWFGWSAGRIINLDIGGGSLELSSGVDEE
MLBr_02434|M.leprae_Br4923 GVRLQVLRGVDESRLTFLAVRRWFGWSAGRIINLDIGGGSLELSNGVDEE
Mb0507|M.bovis_AF2122/97 GVELQALRGEDESRLTFLAVRRWYGWSAGRILNLDIGGGSLEVSSGVDEE
Rv0496|M.tuberculosis_H37Rv GVELQALRGEDESRLTFLAVRRWYGWSAGRILNLDIGGGSLEVSSGVDEE
MAV_4656|M.avium_104 GVELRVLTGVDESRLTFLAVRRWYGWSAGRIINLDIGGGSLEMSSGLDEE
MAB_4013c|M.abscessus_ATCC_199 GVDLAVLSGVNESRLTFLAVRRWYGWSAGRIINLDIGGGSLEMSCGVDEE
Mflv_0079|M.gilvum_PYR-GCK GVELKVLSGVDESRLTFLAVRRWYGWSAGRIVNIDIGGGSLELSSGVDEE
Mvan_0833|M.vanbaalenii_PYR-1 GVDLRVLSGVDESRLTFLAVRRWYGWSAGRIINIDIGGGSLELSSGVDEE
MSMEG_0939|M.smegmatis_MC2_155 GVSLQVLSGVDESRLTFLAVRRWYGWSAGRIINIDIGGGSLELSNGVDEE
TH_0881|M.thermoresistible__bu GVSLQVLRGVDESRLTFLAVRRWYGWSAGRIINIDIGGGSLELSNGVDEE
.* * .* * :************:*******:*:********:* *:***
MMAR_0822|M.marinum_M PEVALSLPLGAGRLTREWLPDDPPGRRRVAMLRDWLDAELSDASVTMLDA
MUL_4566|M.ulcerans_Agy99 PGVALSLPLGAGRLTREWLPDDPPGRRRVAMLRDWLDAELPDASVTMLDA
MLBr_02434|M.leprae_Br4923 PEVALSLPLGAGRLTREWLPDDPPGRRRVAMLRDWLDSELSDASVTVLEA
Mb0507|M.bovis_AF2122/97 PEIALSLPLGAGRLTREWLPDDPPGRRRVAMLRDWLDAELAEPSVTVLEA
Rv0496|M.tuberculosis_H37Rv PEIALSLPLGAGRLTREWLPDDPPGRRRVAMLRDWLDAELAEPSVTVLEA
MAV_4656|M.avium_104 PEVALSLPLGAGRLTREWLPDDPPGRRRVAMLRDWLDAELAEASENILEA
MAB_4013c|M.abscessus_ATCC_199 PDIALSLPLGAGRLTREWLAEDPPGRRRVAMLRDWLESELVDAAKQVAAA
Mflv_0079|M.gilvum_PYR-GCK PDVALSLPLGAGRMTREWLPDDPPGRRRVAMLRDWLTNELSDAAAAVTEA
Mvan_0833|M.vanbaalenii_PYR-1 PDVALSLPLGAGRMTREWLPDDPPGRRRVAVLRDWLSNELSEPAAAIAEA
MSMEG_0939|M.smegmatis_MC2_155 PEVALSLPLGAGRLTREWLPDDPPGRRAVAMLRDWLATELADAGATIRRA
TH_0881|M.thermoresistible__bu PDVALSLPLGAGRLSREWLPDDPPGRRRVAMLRDWLATELAEPAATVLAA
* :**********::****.:****** **:***** ** :.. : *
MMAR_0822|M.marinum_M GIPDLAVATSKTFRSLARLTGAAPSAAGPRVKRTLTANGLRQLISFISRM
MUL_4566|M.ulcerans_Agy99 GIPDLAVATSKTFRSLARLTGAAPSAAGPRVKRTLTANGLRQLISFISRM
MLBr_02434|M.leprae_Br4923 GKPDLAVATSKTFRSLARLTGAAPSAAGPRAKRALTVNGLRQLIAFISRM
Mb0507|M.bovis_AF2122/97 GSPDLAVATSKTFRSLARLTGAAPSMAGPRVKRTLTANGLRQLIAFISRM
Rv0496|M.tuberculosis_H37Rv GSPDLAVATSKTFRSLARLTGAAPSMAGPRVKRTLTANGLRQLIAFISRM
MAV_4656|M.avium_104 GTPDLTVATSKTFRSLARLTGAAPSGAGPRVKRTLTANGLRQLISFISRM
MAB_4013c|M.abscessus_ATCC_199 GVPDLAVASSKTFRSLARLTGAAPSGAGPRVKRTLTASGLRQLIAFISRM
Mflv_0079|M.gilvum_PYR-GCK GTPDLAVASSKTFRSLARLTGAAPSGAGPRVKRTLTATGLRQLINFISRM
Mvan_0833|M.vanbaalenii_PYR-1 GAPDLAVASSKTFRSLARLTGAAPSGAGPRVKRTLTASGLRQLINFISRM
MSMEG_0939|M.smegmatis_MC2_155 GAPDLAVATSKTFRSLARLTGAAPSGAGPRVKRTLTATGLRQLIAFISRM
TH_0881|M.thermoresistible__bu GSPDLVVASSKTFHSLARLTGAAPSAAGPRVRRTVTATGLRQVIAFISRM
* ***.**:****:*********** ****.:*::*..****:* *****
MMAR_0822|M.marinum_M TTADRAELEGVSAERAPQIVAGALVAEASMRALSIEALDICPWALREGVI
MUL_4566|M.ulcerans_Agy99 TTADRAELEGVSAERARQIVAGALVAEASMRALSIEALDICPWALREGVI
MLBr_02434|M.leprae_Br4923 TASDRAELEGISTERAPQIVAGALVAEASMRALSIETVDICPWALREGLI
Mb0507|M.bovis_AF2122/97 TAVDRAELEGVSADRAPQIVAGALVAEASMRALSIEAVEICPWALREGLI
Rv0496|M.tuberculosis_H37Rv TAVDRAELEGVSADRAPQIVAGALVAEASMRALSIEAVEICPWALREGLI
MAV_4656|M.avium_104 TTADRAELEGVSAERAPQIVAGALVAEASMRALSIESVDICPWALREGLI
MAB_4013c|M.abscessus_ATCC_199 TTADRAELEGVSVDRAPQIVAGALVAEASMRALSLEAVDICPWALREGLI
Mflv_0079|M.gilvum_PYR-GCK TAADRAELEGVSADRAPQIVAGALVAEASMNALNIESVDICPWALREGLI
Mvan_0833|M.vanbaalenii_PYR-1 TAADRAELEGVSADRAPQIVAGALVAEASMKALGIESVDICPWALREGLI
MSMEG_0939|M.smegmatis_MC2_155 TAADRAELEGVSAERAPQIVAGALVAEASMRALEIESVDICPWALREGLI
TH_0881|M.thermoresistible__bu TTADRAELEGVSADRAPQIVAGALIAEAAMKALEVETVDICPWALREGLI
*: *******:*.:** *******:***:*.** :*:::*********:*
MMAR_0822|M.marinum_M LRRLDSEGDGTA------FMETSPV--------LTSVRDARGQVVDRNAA
MUL_4566|M.ulcerans_Agy99 LRRLDSEGDGTA------FMETSPV--------LTSVRDARGQVVDRNAA
MLBr_02434|M.leprae_Br4923 LRKLDSEADGTA------LVQTS-------------VRDTRGQEVDRNAA
Mb0507|M.bovis_AF2122/97 LRKLDSEADGTA------LIESSSV--------HTSVRAVGGQPADRNAA
Rv0496|M.tuberculosis_H37Rv LRKLDSEADGTA------LIESSSV--------HTSVRAVGGQPADRNAA
MAV_4656|M.avium_104 LRKLDSEADGTA------LMEPS-------------VRNAGGQVVDRNQ-
MAB_4013c|M.abscessus_ATCC_199 LRKLDSEADGTA------FVD-----------------------------
Mflv_0079|M.gilvum_PYR-GCK LRKLDSEADGSD------FVGGSFN--------QVSGRGKAAKT-GARES
Mvan_0833|M.vanbaalenii_PYR-1 LRKLDSEADGSA------LVGGTDDSGGSGKPGKVGGTDKAGKADGGESA
MSMEG_0939|M.smegmatis_MC2_155 LRKLDSEADGTA------LVAAAAR-----------------------DA
TH_0881|M.thermoresistible__bu LRKLDSEAVGGSGTDHPFDVGGADNPATIDADQFATVSPSAREAGAMHPA
**:****. * :
MMAR_0822|M.marinum_M GRSRGNKP-----
MUL_4566|M.ulcerans_Agy99 GRSRGNKP-----
MLBr_02434|M.leprae_Br4923 NRSRGDKT-----
Mb0507|M.bovis_AF2122/97 NRSRGSKP-----
Rv0496|M.tuberculosis_H37Rv NRSRGSKP-----
MAV_4656|M.avium_104 NRSRGDKP-----
MAB_4013c|M.abscessus_ATCC_199 -------------
Mflv_0079|M.gilvum_PYR-GCK ARTADART-----
Mvan_0833|M.vanbaalenii_PYR-1 ARPMSVRNAGR--
MSMEG_0939|M.smegmatis_MC2_155 GR-----------
TH_0881|M.thermoresistible__bu STTSPAGPRGNTR