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GVNDRRVGAIDCGTNSIRLLIAEPDGARLRDVHREMRIVRLGQGVDATGQFAPEALARTEAALADYVALM IEHSVSAVRMVATSAARDAGNRDEFFSMTARLLGKVVPGAVAEVITGTEEAELSFRGAVGELDPAAAPFV VVDLGGGSTELVLGTGAVQASFSADIGCVRLTERCLHSDPPTAEEIADARAVVRAGLAQALEVVPVNEAR TWVGVAGTMTTLSALAQNMTEYDPEQIHLSRIGFDGLLRVCDELIGMTKEQRLALGPMHHGRADVIGGGA VIVEELAAVLADRAGIDQLVVSEHDILDGIALSIS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5413 | - | - | 100% (316) | exopolyphosphatase |
| M. smegmatis MC2 155 | MSMEG_0939 | - | 1e-14 | 23.61% (288) | Ppx/GppA phosphatase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1054 | - | 1e-119 | 70.70% (314) | hypothetical protein Mb1054 |
| M. gilvum PYR-GCK | Mflv_1957 | - | 1e-129 | 74.53% (318) | Ppx/GppA phosphatase |
| M. tuberculosis H37Rv | Rv1026 | - | 1e-119 | 70.70% (314) | hypothetical protein Rv1026 |
| M. leprae Br4923 | MLBr_00258 | - | 1e-119 | 71.02% (314) | hypothetical protein MLBr_00258 |
| M. abscessus ATCC 19977 | MAB_1168 | - | 1e-120 | 71.38% (311) | hypothetical protein MAB_1168 |
| M. marinum M | MMAR_4459 | - | 1e-124 | 73.63% (311) | hypothetical protein MMAR_4459 |
| M. avium 104 | MAV_1167 | - | 1e-121 | 73.31% (311) | exopolyphosphatase |
| M. thermoresistible (build 8) | TH_0859 | - | 1e-128 | 75.64% (312) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4628 | - | 1e-115 | 72.15% (298) | hypothetical protein MUL_4628 |
| M. vanbaalenii PYR-1 | Mvan_4768 | - | 1e-127 | 74.76% (313) | Ppx/GppA phosphatase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1957|M.gilvum_PYR-GCK --MSSRRVAAVDCGTNSIRLLIADVDPNGQGGGLRDVHREMRIVRLGQGV
Mvan_4768|M.vanbaalenii_PYR-1 -----MRVAAVDCGTNSIRLLVADA----AGDGLHDVHREMRIVRLGQGV
TH_0859|M.thermoresistible__bu VDPAVGRVAAVDCGTNSIRLLIADR--AGPGGRLRDVHREMRIVRLGQGV
MSMEG_5413|M.smegmatis_MC2_155 MGVNDRRVGAIDCGTNSIRLLIAEP----DGARLRDVHREMRIVRLGQGV
Mb1054|M.bovis_AF2122/97 --MALTRVAAIDCGTNSIRLLIADVGAGLARGELHDVHRETRIVRLGQGV
Rv1026|M.tuberculosis_H37Rv --MALTRVAAIDCGTNSIRLLIADVGAGLARGELHDVHRETRIVRLGQGV
MMAR_4459|M.marinum_M ----MSRVAAIDCGTNSIRLLIADAGG----GQLNDVHRETRIVRLGQGV
MUL_4628|M.ulcerans_Agy99 -------------------MLIADAGG----GQLNDVQRETRIVRLGQGV
MLBr_00258|M.leprae_Br4923 ----MSRVAAIDCGTNSIRLLIADVAG----RKLRDVHREMRIVRLGQGV
MAV_1167|M.avium_104 ---MTGRLAGIDCGTNSIRLLIADVRD----GRLRDVHRETRIVRLGQGV
MAB_1168|M.abscessus_ATCC_1997 ----MTRVAAVDCGTNSIRLLVSDIDD---SGRLTDVHREMRIVRLGQGV
:*::: * **:** *********
Mflv_1957|M.gilvum_PYR-GCK DATGEFAPEALARTHSALAGYAEVMRRHEVDAVRMVATSAARDVSNREQF
Mvan_4768|M.vanbaalenii_PYR-1 DATGEFAPDALARTRAALTGYAEVMRRHGVDAVRMVATSAARDVANRDEF
TH_0859|M.thermoresistible__bu DATGEFAPEALERTRAALTDYAELMRAHGVAEVRMVATSAARDVINRDAF
MSMEG_5413|M.smegmatis_MC2_155 DATGQFAPEALARTEAALADYVALMIEHSVSAVRMVATSAARDAGNRDEF
Mb1054|M.bovis_AF2122/97 DATGRFAPEAIARTRTALTDYAELLTFHHAERVRMVATSAARDVVNRDVF
Rv1026|M.tuberculosis_H37Rv DATGRFAPEAIARTRTALTDYAELLTFHHAERVRMVATSAARDVVNRDVF
MMAR_4459|M.marinum_M DATGQFAPEAIARTRAALTDYAALLKVHGVERVRMVATSATRDAANRDSF
MUL_4628|M.ulcerans_Agy99 DATGQFAPEAIARTRAALTDYAALLKVHGVERVRMVATSATRDAANRDSF
MLBr_00258|M.leprae_Br4923 DATGEFALDAIARTRAALVDYTALLSAHRVERVRMVATSAARDVVNRDVL
MAV_1167|M.avium_104 DATGEFAPEAIARTRAALSDYADLLKQHGVQRVRMVATSAARDVGNRADF
MAB_1168|M.abscessus_ATCC_1997 DATGEFAPEAIERTRAALAAYTQLMTSLGVERVRMVATSAARDVSNRDVF
****.** :*: **.:** *. :: . ********:**. ** :
Mflv_1957|M.gilvum_PYR-GCK FAMTSEVLGGVVPGAVAEVITGAEEAELSFRGAVGELDSAAAPFVVVDLG
Mvan_4768|M.vanbaalenii_PYR-1 FAMTSEVLGTVVPGAVAEVITGTEEAELSFRGAVGELDAAAAPFVVVDLG
TH_0859|M.thermoresistible__bu FAMTAEVLGTVVPGAVAEVITGAEEAELSFRGAVAELDSAAAPFVVVDLG
MSMEG_5413|M.smegmatis_MC2_155 FSMTARLLGKVVPGAVAEVITGTEEAELSFRGAVGELDPAAAPFVVVDLG
Mb1054|M.bovis_AF2122/97 FAMTADVLGAALPGSAAEVITGAEEAELSFRGAVGELGSAGAPFVVVDLG
Rv1026|M.tuberculosis_H37Rv FAMTADVLGAALPGSAAEVITGAEEAELSFRGAVGELGSAGAPFVVVDLG
MMAR_4459|M.marinum_M FAMTAEVLGAVLPGAIAEVITGAEEAELSFSGAVGELDSAGAPFVVVDLG
MUL_4628|M.ulcerans_Agy99 FAMTAEVLGAVLPGAIAEVITGAEEAELSFSGAVGELDSAGAPFVVVDLG
MLBr_00258|M.leprae_Br4923 FAMTADVLGTVIPGSVAEVITGAEEADLSFDGAVGELDSAGAPFVVIDLG
MAV_1167|M.avium_104 FSMTADVLGAVLPGAVAEVITGADEAELSFRGAVGELDSAAGPFVVVDLG
MAB_1168|M.abscessus_ATCC_1997 FAMTAELLGAVIPGAIAEVITGTEEAALSFAGAVGELDPAAAPFVVVDLG
*:**: :** .:**: ******::** *** ***.**..*..****:***
Mflv_1957|M.gilvum_PYR-GCK GGSTEVVVGSE----DVVAAHSADIGCVRLTERCLRSDPPTDGEIADARA
Mvan_4768|M.vanbaalenii_PYR-1 GGSTEVVLGSDRDVRAVVAGYSADIGCVRLTERCLRSDPPTDDEIAAARA
TH_0859|M.thermoresistible__bu GGSTEVVLGAT----EVAAAVSADIGCVRLTERCLPSDPPTAAEIDAARA
MSMEG_5413|M.smegmatis_MC2_155 GGSTELVLGTG----AVQASFSADIGCVRLTERCLHSDPPTAEEIADARA
Mb1054|M.bovis_AF2122/97 GGSTEIVLG----EHEVVASYSADIGCVRLTERCLHSDPPTLQEVSTARR
Rv1026|M.tuberculosis_H37Rv GGSTEIVLG----EHEVVASYSADIGCVRLTERCLHSDPPTLQEVSTARR
MMAR_4459|M.marinum_M GGSTEIVLGK--AGNEVTASYSANIGCVRLTERCLHSDPPTPDEVAAARL
MUL_4628|M.ulcerans_Agy99 GGSTEIVLGK--AGNEVTASYSANIGCVRLTERCLHSDPPTPDEVAAARL
MLBr_00258|M.leprae_Br4923 GGSTEIVLGGGSAECGVVASYSADIGCVRLTERCLHSDPPTPEEVAAARK
MAV_1167|M.avium_104 GGSTEIVVGG---SDGVTASHSADIGCVRLTERCLHSDPPTPEEVALARQ
MAB_1168|M.abscessus_ATCC_1997 GGSTETVIGDS---SGVEASFSADIGCVRLTERCLHSDPPVADEIAAARE
***** *:* * *. **:*********** ****. *: **
Mflv_1957|M.gilvum_PYR-GCK VVREALAQVLTAVPVDQARTWVGVAGTMTTLAALAHKMTVYDSDAIHLSR
Mvan_4768|M.vanbaalenii_PYR-1 VVREALADVLAAVPVERAHTWVGVAGTMTTLAALARKLTTYDADAIHLSR
TH_0859|M.thermoresistible__bu VVRGALDEVIRRVPVERARTWVGVAGTMTTLAALAHDLASYDSEAIHLSR
MSMEG_5413|M.smegmatis_MC2_155 VVRAGLAQALEVVPVNEARTWVGVAGTMTTLSALAQNMTEYDPEQIHLSR
Mb1054|M.bovis_AF2122/97 LVRERLEPALRTVPLELARTWVGLAGTMTTLSALAQSMTAYDAAAIHLSR
Rv1026|M.tuberculosis_H37Rv LVRERLEPALRTVPLELARTWVGLAGTMTTLSALAQSMTAYDAAAIHLSR
MMAR_4459|M.marinum_M VVREELEPALRAVPVEEARTWVGLAGTMTTLSALAHNMTAYDAAAIHLSR
MUL_4628|M.ulcerans_Agy99 VVREELEPALRAVPVEEARTWVGLAGTMTTLSALAHNMTTYDAAAIHLSR
MLBr_00258|M.leprae_Br4923 VVRERLEVALQMVSVEQARTWVGLAGTMTTLSALAQNMMTYDAAAIHLSR
MAV_1167|M.avium_104 VVRERLEVALGVVPVEGARTWVGVAGTMTTLSALAHDLPAYDSAAIHLSR
MAB_1168|M.abscessus_ATCC_1997 AVRAQLARTFEVVPVRTAHTWVGVAGTFTTLAALAHRLDVYDPAAIHLSR
** * .: *.: *:****:***:***:***: : **. *****
Mflv_1957|M.gilvum_PYR-GCK VAFDGLLPVCADLLAMTRKQRAVLGPMHEGRVDVIGGGALIVQELAAMLG
Mvan_4768|M.vanbaalenii_PYR-1 IPFDDLLPVCADLLAMTRQQRAVLGPMHEGRVDVIGGGALIVQELAAVLG
TH_0859|M.thermoresistible__bu VGFSDLLRVCDDLVAMTRQQRAALGPMHEGRVDVIGGGAIIVEELAALLR
MSMEG_5413|M.smegmatis_MC2_155 IGFDGLLRVCDELIGMTKEQRLALGPMHHGRADVIGGGAVIVEELAAVLA
Mb1054|M.bovis_AF2122/97 VPGADLLEVCQRLIGMTRKQRAALAPMHPGRADVIGGGAIVVEELARELR
Rv1026|M.tuberculosis_H37Rv VPGADLLEVCQRLIGMTRKQRAALAPMHPGRADVIGGGAIVVEELARELR
MMAR_4459|M.marinum_M VAGADLHAVCDRLIAMTREQRAALPPMHEGRVDVIGGGAIVVEELARELR
MUL_4628|M.ulcerans_Agy99 VAGADLHAVCDLLIAMTREQRAALPPMHEGRVDVIGGGAIVVESLARELR
MLBr_00258|M.leprae_Br4923 VRGSDLMEVCDRLIGMTRVQRVALPSMHASRADVIGGGAVLVQELVRELR
MAV_1167|M.avium_104 VSGRDLLAVCERLIGMTRAQRAALPPMHAGRADVIAGGAVVVEELAREFR
MAB_1168|M.abscessus_ATCC_1997 VPLSRLAEVTSSLIAMPRAQRAALGPMHEGRVDVIGGGSIVVEELARELS
: * * *:.*.: ** .* .** .*.***.**:::*:.*. :
Mflv_1957|M.gilvum_PYR-GCK ERAGIAELVVSEHDILDGIALSIA-
Mvan_4768|M.vanbaalenii_PYR-1 ERAGITELVVSEHDILDGIALSII-
TH_0859|M.thermoresistible__bu QRAGIEELIVSEHDILDGIALSIS-
MSMEG_5413|M.smegmatis_MC2_155 DRAGIDQLVVSEHDILDGIALSIS-
Mb1054|M.bovis_AF2122/97 ERAGIDQLTVSEHDILDGIALSLAG
Rv1026|M.tuberculosis_H37Rv ERAGIDQLTVSEHDILDGIALSLAG
MMAR_4459|M.marinum_M SRAGIDELTVSEHDILDGIALALCD
MUL_4628|M.ulcerans_Agy99 SRAGIDELTVSEHDILDGIALALCD
MLBr_00258|M.leprae_Br4923 TWAGIDELIVSERDILDGIVLSIAG
MAV_1167|M.avium_104 ARAGIDELTVSEHDILDGIVLSIAG
MAB_1168|M.abscessus_ATCC_1997 ERAGITELVVSEHDILDGIAISLR-
*** :* ***:******.:::