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M. smegmatis MC2 155 MSMEG_0858 (-)

annotation: cell division control protein Cdc48
coordinates: 940749 - 942986
length: 745

SQGFDDEFGGADQYDTPLSHLRLTARLNTSALDSRRGVVRLHPEVLAALGIREWDAVALTGTRTTAAVAG
VAGPGVPAGTALLDDVTLSNAGVRENAAVLVSPVTVYGARSVTVSGSRLATQSISPATLRMALLGKVMTV
GDTVSLLPRDLGPGTSTSAATSALASSVGITWTSELLTVTAVDPPGTVSVQPNSVVSWGTGTPEDPAPPP
TGRHTVSPQRSEQPVSFDDVKVTHPQAVKLDEWLRLSLDEPELLKTLGATPHLGVLVSGPAGVGKATMVR
AVCASRRVVELDGPEVGALQVDERLRSVTSAVAAVTESGGVLFIADVDALLPAGNEMRPPEPVATLILAE
LRKAVATPGVAFIATSAVPENVDARLRAPEVCDRELGLSLPDATARRSLLEMLLRGVPSEDLDLGDIADH
TPGFVVADLAAVVREGALRAAARASSSDDDPVLRHADLEGALTVIRPLSRSASEEVSVGSVTLDDVGDMV
ETKRALTEAVLWPLQHPDTFSRLGIDPPRGVLLYGPPGCGKTFVVRALASSGRLSVHAVKGSELMDKWVG
SSEKAVRELFARARDSAPSLVFLDEIDALAPRRGQNFDSGVTDKVVASLLTELDGIEPLRDVVVLGATNR
PDLIDPALLRPGRLERLVFVEPPDAAARRDILRTAGKSIPLADDVDLDSLADDLDGYSAADCVALLRESA
MTAMRRSIDAADVTAADVAKARETVRPSLDPAQVESLREFAEKR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0858--100% (745)cell division control protein Cdc48
M. smegmatis MC2 155MSMEG_6105-3e-4338.17% (241) cell division protein
M. smegmatis MC2 155MSMEG_3902-2e-4138.74% (253) ATPase, AAA family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0443c-0.074.69% (727) putative ATPase
M. gilvum PYR-GCKMflv_0155-0.077.28% (735) vesicle-fusing ATPase
M. tuberculosis H37RvRv0435c-0.074.69% (727) putative ATPase
M. leprae Br4923MLBr_00222ftsH3e-4439.00% (241) putative integral membrane peptidase
M. abscessus ATCC 19977MAB_0637c-0.075.17% (733) putative ATPase
M. marinum MMMAR_0752-0.075.38% (723) ATPase
M. avium 104MAV_4716-0.075.62% (722) cell division protein 48
M. thermoresistible (build 8)TH_2865-0.077.59% (754) PUTATIVE Vesicle-fusing ATPase
M. ulcerans Agy99MUL_1384-0.075.14% (724) ATPase
M. vanbaalenii PYR-1Mvan_0749-0.077.27% (739) vesicle-fusing ATPase

CLUSTAL 2.0.9 multiple sequence alignment


Mb0443c|M.bovis_AF2122/97           ------------MTHPDPARQLTLTARLNTSAVDSRRGVVRLHPNAIAAL
Rv0435c|M.tuberculosis_H37Rv        ------------MTHPDPARQLTLTARLNTSAVDSRRGVVRLHPNAIAAL
MMAR_0752|M.marinum_M               ------------MTSPYGAPQLTLTARLNTSAVDSRRGVVRLHPSAIAAL
MUL_1384|M.ulcerans_Agy99           ------------MTSPYGAPQLTLTARLNTSAVDSRRGVVRLHPSAIAAL
MAV_4716|M.avium_104                ------------MTGSGSARQLTLTARLNTSAVDSRRGVVRLHPSAVAAL
Mflv_0155|M.gilvum_PYR-GCK          ------------------MAQLTLTARLNTSALDSRRGVVRLHPEAIAAL
Mvan_0749|M.vanbaalenii_PYR-1       -----MSELHQSAEHRPPRAHLTLTARLNTSALDSRRGVVRLHPEAIAAL
TH_2865|M.thermoresistible__bu      -------VTVTTDVPEPELNQLRLTARLNTSALDSRRGVVRLHPEAIAAL
MSMEG_0858|M.smegmatis_MC2_155      MSQGFDDEFGGADQYDTPLSHLRLTARLNTSALDSRRGVVRLHPEVLAAL
MAB_0637c|M.abscessus_ATCC_199      ------------------MSSLTLTARLNTSAVDSRRGVVRLHPEAIAAL
MLBr_00222|M.leprae_Br4923          ------------------------------MLLMNRKNVIRMVT-AIAVV
                                                                    : .*:.*:*: . .:*.:

Mb0443c|M.bovis_AF2122/97           GIREWDAVSLTGSRTTAAVAGLAAADTAVGTVLLDDVTLSNAGLREGTEV
Rv0435c|M.tuberculosis_H37Rv        GIREWDAVSLTGSRTTAAVAGLAAADTAVGTVLLDDVTLSNAGLREGTEV
MMAR_0752|M.marinum_M               GIREWDAVSLTGSRTTAAVAGMADDQVPVGTILLDDVTLSNAGLREGTAV
MUL_1384|M.ulcerans_Agy99           GIREWDAVSLTGSRTTAAVAGMADDQVPVGTILLDDVTLSNAGLREGTAV
MAV_4716|M.avium_104                GIREWDAVSLIGSRTTAAVAGLAGPEIPSGTVLLDDVTLSNAGLRDGTAV
Mflv_0155|M.gilvum_PYR-GCK          GIREWDAVSLTGARTTAAVVGIAPAGTPTGTALLDDVTLSNAGLREDTSV
Mvan_0749|M.vanbaalenii_PYR-1       GIREWDAVSLTGARTTAAVVGIAPPGTPTGTALLDDVTLSNAGLREDTSV
TH_2865|M.thermoresistible__bu      GLREWDAVSLTGSRTTAAVVGHAPPGTPVGTALLDDVTLSNAGLVEDAPV
MSMEG_0858|M.smegmatis_MC2_155      GIREWDAVALTGTRTTAAVAGVAGPGVPAGTALLDDVTLSNAGVRENAAV
MAB_0637c|M.abscessus_ATCC_199      GIREWDAISLTGSRTTAAVVGVAPRSVPAGTALLDDVTLSNAGLREDASV
MLBr_00222|M.leprae_Br4923          VLLGWSFFYFS-----DDTRGYKFVDTSVAMSQINGHNVKSAQIDDREQQ
                                     :  *. . :        . *      . .   ::. .:..* : :    

Mb0443c|M.bovis_AF2122/97           IVSPVTVYGARSVTLSGSTLATQSVPPVTLRQALLGKVMTVGDAVSLLPR
Rv0435c|M.tuberculosis_H37Rv        IVSPVTVYGARSVTLSGSTLATQSVPPVTLRQALLGKVMTVGDAVSLLPR
MMAR_0752|M.marinum_M               LVNSVTVYGARTVTLSGSSLATQSLSPITLRQALLGKVMTVGDAVSLLPR
MUL_1384|M.ulcerans_Agy99           LVNSVTVYGARTVTLSGSSLATQSLSPITLRQALLGKVMTVGDAVSLLPR
MAV_4716|M.avium_104                VVSPVTVYGARSVTLSGSPLTTRSVSPVTLRQALLGKVLTVGDAVSLLPR
Mflv_0155|M.gilvum_PYR-GCK          LVSDVTVYGARSVTLSGSRLASRSITPATLRQALLGKVMTVGDTVSLLPR
Mvan_0749|M.vanbaalenii_PYR-1       LVAPVTVYGARCVTLSGSKLAMQSITAATLRQALLGKVMTVGDTVSLLPR
TH_2865|M.thermoresistible__bu      LVAPVTVYGARSVTVAGSRLASGSISPATLRQALLGKVMTVGDTVSLLPR
MSMEG_0858|M.smegmatis_MC2_155      LVSPVTVYGARSVTVSGSRLATQSISPATLRMALLGKVMTVGDTVSLLPR
MAB_0637c|M.abscessus_ATCC_199      IVAAVTVYGARSITVSGSSIATQSVSSATLRMALLGKVMTVGDTVSLLPR
MLBr_00222|M.leprae_Br4923          LRLTLKKGNNDTDGSDKVITKYPTGYAVDLFNALSAKNTKVTTAVN----
                                    :   :.  .              :  .  *  ** .*  .*  :*.    

Mb0443c|M.bovis_AF2122/97           DLGPGTSTSAASRALAAAVGISWTSELLTVTGVDPDGPVSVQPNSLVTWG
Rv0435c|M.tuberculosis_H37Rv        DLGPGTSTSAASRALAAAVGISWTSELLTVTGVDPDGPVSVQPNSLVTWG
MMAR_0752|M.marinum_M               DLGPGTSTSAASQALASAVGISWTSELLTVTGVDPDAPVSVQPNTLVTWG
MUL_1384|M.ulcerans_Agy99           DLGPGTSTSAASQALASAVGISWTSELLTVTGVDPDAPVSVQPNTLVTWG
MAV_4716|M.avium_104                DLGPGTSTSEATRALAAAVGISWTSELLTVTGVDPDGPVSVQPNSLVGWG
Mflv_0155|M.gilvum_PYR-GCK          DLGPGTSTSTASAALASSVGITWTSELLTVTAADPIGPVSVQPNSLVCWA
Mvan_0749|M.vanbaalenii_PYR-1       DLGPGTSTSAASAALASSVGITWTSELLTVTSVDPAGPVSVQPNSLVNWG
TH_2865|M.thermoresistible__bu      DLGPGTSTSAATTALAASVGITWTSELLTVTAVDPPGPVSVQPNSVVAWA
MSMEG_0858|M.smegmatis_MC2_155      DLGPGTSTSAATSALASSVGITWTSELLTVTAVDPPGTVSVQPNSVVSWG
MAB_0637c|M.abscessus_ATCC_199      DLGPGTSTSEATSALTRSVGITWTSELLTVTAVDPDGPVSVQPNSLVSWQ
MLBr_00222|M.leprae_Br4923          ------EGSILGELLVYVLPLLLLVGLFVMFSRMQGG-------------
                                          . *     *.  : :     *:.: .    .             

Mb0443c|M.bovis_AF2122/97           AGVPAAMGTSTAGQVSISSP--------------EIQIEELKGAQPQAAK
Rv0435c|M.tuberculosis_H37Rv        AGVPAAMGTSTAGQVSISSP--------------EIQIEELKGAQPQAAK
MMAR_0752|M.marinum_M               TGVPHTAQSSQAERVSVATP--------------EIQVEELKGAQPQAAK
MUL_1384|M.ulcerans_Agy99           TGVPHTAQSSQAERVSVATP--------------EIQVEELKGAQPQAAK
MAV_4716|M.avium_104                ARAAPAAASRVS--VEVARP--------------QTVVEELKGCQPQAAK
Mflv_0155|M.gilvum_PYR-GCK          SGASEASGTSEAANGTSEVSGAPVRTEQP--RTQAVGFDDLKGAHAQAGR
Mvan_0749|M.vanbaalenii_PYR-1       TSTATPAAPPEGT-GQHVVT----TSAES--TTPAVSYDDLKGSHAQAAR
TH_2865|M.thermoresistible__bu      DSTGTHGTGTHGTGTHGTGTAAPARPPGPGRARPDFTVEDLKGAQSQAER
MSMEG_0858|M.smegmatis_MC2_155      TGTPEDPAPPPTG--RHTVS--PQRSEQP------VSFDDVKVTHPQAVK
MAB_0637c|M.abscessus_ATCC_199      GSTATSATSATAARQTELAPAAGPAPAAS----TVISVEDLKGSQAQATR
MLBr_00222|M.leprae_Br4923          ARMGFGFGKSRAKQLSKDMP--------------KTTFADVAGVDEAVEE
                                                       .                   ::   .  . .

Mb0443c|M.bovis_AF2122/97           LTEWLKLALDEPHLLQTLGAGTNLGVLVSGPAGVGKATLVRAVCDGR--R
Rv0435c|M.tuberculosis_H37Rv        LTEWLKLALDEPHLLQTLGAGTNLGVLVSGPAGVGKATLVRAVCDGR--R
MMAR_0752|M.marinum_M               LTEWLKLALDEPHLLQSLGAGTNLGVLVSGPAGVGKVTLVRAVCAGR--R
MUL_1384|M.ulcerans_Agy99           LTEWLKLALDEPHLLQSLGAGTNLGVLASGPAGVGKVTLVRAVCAGR--R
MAV_4716|M.avium_104                LVEWLKLALDEPHLLKTLGAATFLGVLVTGPAGVGKVTLVRAVCGDR--R
Mflv_0155|M.gilvum_PYR-GCK          LTEWLKLALDQPELLEKLGATANLGVLVSGPAGVGKATLVRTVCAER--R
Mvan_0749|M.vanbaalenii_PYR-1       LTEWLKLAIDQPELLEKLGATSNLGVLVSGPAGVGKATLVRTVCAGR--R
TH_2865|M.thermoresistible__bu      LTEWLKLALDEPELLETLGATPHLGVLVSGPHGVGKATLVRVVCAHR--R
MSMEG_0858|M.smegmatis_MC2_155      LDEWLRLSLDEPELLKTLGATPHLGVLVSGPAGVGKATMVRAVCASR--R
MAB_0637c|M.abscessus_ATCC_199      LTEWLKLALDEPELLKTLGAQPNLGVLISGPAGVGKATLARAVCAAR--T
MLBr_00222|M.leprae_Br4923          LYEIKDFLQN-PCRYQTLGAKIPKGVLLYGPPGTGKTLLARAVAGEAGVP
                                    * *   :  : *   :.***    ***  ** *.**. :.*.*.      

Mb0443c|M.bovis_AF2122/97           LVTLDGPEIGALAAGDRVKAVASAVQAVRHEG-GVLLITDADALLP----
Rv0435c|M.tuberculosis_H37Rv        LVTLDGPEIGALAAGDRVKAVASAVQAVRHEG-GVLLITDADALLP----
MMAR_0752|M.marinum_M               LVELDGPEVGALAPENRLKAVASAVATVRDGG-GVLLITDVDALLP----
MUL_1384|M.ulcerans_Agy99           LVELDGPEVGALAPENRLKAVASAVATVRDGG-GVLLITDVDALLP----
MAV_4716|M.avium_104                LVTLDGPEVGALGADDRLKAVASAVQTVRDGG-GVLLITDVDALLP----
Mflv_0155|M.gilvum_PYR-GCK          LIELDGPEVGSLRADDRLAAVSSAAASARDGG-GVLLVTDIDALLP----
Mvan_0749|M.vanbaalenii_PYR-1       LIELDGPEVGSLRPEDRLANVSSAVAAVRDGG-GVLLVTDVDALLP----
TH_2865|M.thermoresistible__bu      LVELDGPEIGALPAEERLRRVSETVATVRDGG-GVLLITDVDALLPQ---
MSMEG_0858|M.smegmatis_MC2_155      VVELDGPEVGALQVDERLRSVTSAVAAVTESG-GVLFIADVDALLPAG--
MAB_0637c|M.abscessus_ATCC_199      LIELDGPEAGATSADGRLDMIREAVSRVRQSG-GVLLISDIDALLP----
MLBr_00222|M.leprae_Br4923          FFTISGSDFVEMFVGVGASRVRDLFDQAKQNSPCIIFVDEIDAVGRQRGT
                                    .. :.*.:            : .    . . .  :::: : **:      

Mb0443c|M.bovis_AF2122/97           ------AAAEPVASLILSELRTAVATAGVVLIATSARPDQLDARLRSPEL
Rv0435c|M.tuberculosis_H37Rv        ------AAAEPVASLILSELRTAVATAGVVLIATSARPDQLDARLRSPEL
MMAR_0752|M.marinum_M               ------ATAEPVAALILGELRTAVATDGVVLIATTAAPDQLDARLRAPDL
MUL_1384|M.ulcerans_Agy99           ------ATAEPVAALILGELRTAVATDGVVLIATTAAPDQLDARLRAPDL
MAV_4716|M.avium_104                ------ATAEPVASLILAELRGAVASEGVALIATSARPDQLDARLRAPDL
Mflv_0155|M.gilvum_PYR-GCK          ------VPPDPVATLILTELRSAVAG-GVVFVATSAVPDNVDPRLRAPDL
Mvan_0749|M.vanbaalenii_PYR-1       ------VPAEPVATLILTELRSAVATRGVAFVATTAVPDNVDPRLRAPDL
TH_2865|M.thermoresistible__bu      ---SADRPAEPVATAILAELRDAVATRGVAFIATSAVPDAVDTRLRAPEV
MSMEG_0858|M.smegmatis_MC2_155      ---NEMRPPEPVATLILAELRKAVATPGVAFIATSAVPENVDARLRAPEV
MAB_0637c|M.abscessus_ATCC_199      ------AAAEPVATLILAELRTAVATSGVAFIATTAHPDALDARLRGPEL
MLBr_00222|M.leprae_Br4923          GLGGGHDEREQTLNQLLVEMDGFGDRAGVILIAATNRPDILDPALLRPGR
                                             : .   :* *:       ** ::*::  *: :*. *  *  

Mb0443c|M.bovis_AF2122/97           CDRELGLPLPDAATRKSLLEALLNPVPTGD-LNLDEIASRTPGFVVADLA
Rv0435c|M.tuberculosis_H37Rv        CDRELGLPLPDAATRKSLLEALLNPVPTGD-LNLDEIASRTPGFVVADLA
MMAR_0752|M.marinum_M               CDRELGLPLPDAATRKALLEALLRHVPTGD-LDIDEIASRTPGFVVADLA
MUL_1384|M.ulcerans_Agy99           CDRELGLPLPDAATRKALLEALLRHVPTGD-LDIDEIASRTPGFVVADLA
MAV_4716|M.avium_104                CDRELSLPLPDAATRKALLESLLRNVPTDG-LDLDEIASCTPGFVVADLA
Mflv_0155|M.gilvum_PYR-GCK          CDRELGLSLPDGAVRKQLLEVLLRDVPSAN-LEIGEITDRTPGFVVADLA
Mvan_0749|M.vanbaalenii_PYR-1       CDRELGLTLPDGAVRAQLLEVLLRDVPADD-LEISEIADRTPGFVVADLA
TH_2865|M.thermoresistible__bu      CDRELGLPLPDAAIREQQLAVLLRNVPSED-LRLSEIADRTPGFVIADLQ
MSMEG_0858|M.smegmatis_MC2_155      CDRELGLSLPDATARRSLLEMLLRGVPSED-LDLGDIADHTPGFVVADLA
MAB_0637c|M.abscessus_ATCC_199      CDRELGLSLPDAATRKSLLEVLLAKVPSQN-LQLDEIASRTPGFVVADLA
MLBr_00222|M.leprae_Br4923          FDRQIPVSNPDLAGRRAVLRVHSKGKPIADDADLDGLAKRTVGMTGADLA
                                     **:: :. ** : *   *       *  .   :. ::. * *:. *** 

Mb0443c|M.bovis_AF2122/97           ALVREAALRAASRASADGRPPMLHQ--DDLLG------------------
Rv0435c|M.tuberculosis_H37Rv        ALVREAALRAASRASADGRPPMLHQ--DDLLG------------------
MMAR_0752|M.marinum_M               ALLREAALRAASRASTDGQPPELNQ--EDLLG------------------
MUL_1384|M.ulcerans_Agy99           ALLREAALRAASRASTDGQPPELNQ--EDLLG------------------
MAV_4716|M.avium_104                ALIREAALRAASRASSDGRPPALHQ--EDLTG------------------
Mflv_0155|M.gilvum_PYR-GCK          ALVREAALRAAARASENGEPPALRQ--EDLVG------------------
Mvan_0749|M.vanbaalenii_PYR-1       ALVREAALRAAARASENGEKPALRQ--EDLIG------------------
TH_2865|M.thermoresistible__bu      ALIREAALRAAARASATGAAPVLRQ--QDLLG------------------
MSMEG_0858|M.smegmatis_MC2_155      AVVREGALRAAARASSSDDDPVLRH--ADLEG------------------
MAB_0637c|M.abscessus_ATCC_199      ALVREAALRAAARASEKASAPALAQ--EDLIG------------------
MLBr_00222|M.leprae_Br4923          NVVNEAALLTARENGLVITGPALEEAVDRVIGGPRRKGRIISEQEKKITA
                                     ::.*.** :* . .     * * .    : *                  

Mb0443c|M.bovis_AF2122/97           -----------ALTVIRPLS------------------------RSASDE
Rv0435c|M.tuberculosis_H37Rv        -----------ALTVIRPLS------------------------RSASDE
MMAR_0752|M.marinum_M               -----------ALTVIRPLS------------------------RSASSE
MUL_1384|M.ulcerans_Agy99           -----------ALTVIRPLS------------------------RSASSE
MAV_4716|M.avium_104                -----------ALSVIRPLS------------------------RSAAEE
Mflv_0155|M.gilvum_PYR-GCK          -----------ALGVIRPLS------------------------RSATEE
Mvan_0749|M.vanbaalenii_PYR-1       -----------ALGVIRPLS------------------------RSATEE
TH_2865|M.thermoresistible__bu      -----------ALSVIRPLS------------------------RSATEE
MSMEG_0858|M.smegmatis_MC2_155      -----------ALTVIRPLS------------------------RSASEE
MAB_0637c|M.abscessus_ATCC_199      -----------ALSVIRPLS------------------------RSTTEE
MLBr_00222|M.leprae_Br4923          YHEGGHTLAAWAMPDIEPIYKVTILARGRTGGHAVAVPEEDKGLRTRSEM
                                               *:  *.*:                         *: :. 

Mb0443c|M.bovis_AF2122/97           VTVGDVTLDDVGDMAAAKQALTEAVLWPLQHPDTFAR-----LGVEPPRG
Rv0435c|M.tuberculosis_H37Rv        VTVGDVTLDDVGDMAAAKQALTEAVLWPLQHPDTFAR-----LGVEPPRG
MMAR_0752|M.marinum_M               VAVGSITLDDVGDMAQAKQALTEAVLWPLQHPDTFAR-----LGVEPPRG
MUL_1384|M.ulcerans_Agy99           VAVGSITLDDVGDMAQAKQALTEAVLWPLQHPDTFAR-----LGVEPPRG
MAV_4716|M.avium_104                VSVGDITLDDVGDMAQARQALTEAVLWPLQHPDTFAR-----LGVQPPRG
Mflv_0155|M.gilvum_PYR-GCK          VSVGAVTLDDVGDMAETKQALTEAVLWPLQHPETFQR-----LGVEPPRG
Mvan_0749|M.vanbaalenii_PYR-1       VSVGSVTLDDVGDMATTKQALTEAVLWPLQHPETFQR-----LGVQPPRG
TH_2865|M.thermoresistible__bu      VAVGSVTFDDVGDMAETKQALTEAVLWPLQHPDTFAR-----LGVQPPRG
MSMEG_0858|M.smegmatis_MC2_155      VSVGSVTLDDVGDMVETKRALTEAVLWPLQHPDTFSR-----LGIDPPRG
MAB_0637c|M.abscessus_ATCC_199      VAVGSITLDDVGDMVATKQALTEAVLWPLQHPDTFQR-----LGVDPPRG
MLBr_00222|M.leprae_Br4923          IAQLVFAMGGRAAEELVFREPTTGAVSDIEKATKIARSMVTEFGMSSKLG
                                    ::   .::.. .    . :  * ..:  :::. .: *     :*:..  *

Mb0443c|M.bovis_AF2122/97           VLLYGPPGCGKTFVVRALASTGQLSVHAVKGSE-LMDKWVGSSEKAVREL
Rv0435c|M.tuberculosis_H37Rv        VLLYGPPGCGKTFVVRALASTGQLSVHAVKGSE-LMDKWVGSSEKAVREL
MMAR_0752|M.marinum_M               VLLYGPPGCGKTFVVRALASTGQLSVHAVKGSE-LMDKWVGSSEKAVREL
MUL_1384|M.ulcerans_Agy99           VLLYGPPGCGKTFVVRALASTGQLSVHAVKGSE-LMDKWVGSSEKAVREL
MAV_4716|M.avium_104                VLLYGPPGCGKTFVVRALASTGQLSVHAVKGSE-LMDKWVGSSEKAVREL
Mflv_0155|M.gilvum_PYR-GCK          VLLYGPPGCGKTFVVRALASSGRLSVHAVKGAE-LMDKWVGSSEKAVREL
Mvan_0749|M.vanbaalenii_PYR-1       VLLYGPPGCGKTFVVRALASSGRLSVHAVKGAE-LMDKWVGSSEKAVREL
TH_2865|M.thermoresistible__bu      VLLYGPPGCGKTFVVRALASTGRLSVHAVKGAE-LMDKWVGSSEKAVREL
MSMEG_0858|M.smegmatis_MC2_155      VLLYGPPGCGKTFVVRALASSGRLSVHAVKGSE-LMDKWVGSSEKAVREL
MAB_0637c|M.abscessus_ATCC_199      VLLYGPPGCGKTFVVRALASSGRLSVHAVKGAE-LMDKWVGSSEQAVRDL
MLBr_00222|M.leprae_Br4923          AVRYG-SEHGDPFLGRTMGTQADYSHEVARDIDDEVRKLIEAAHTEAWEI
                                    .: ** .  *..*: *::.: .  * ...:. :  : * : ::.  . ::

Mb0443c|M.bovis_AF2122/97           FRRARDSAPSLV-FLDELDALAPRRGQSFDSGVSDRVVAALLTELDG---
Rv0435c|M.tuberculosis_H37Rv        FRRARDSAPSLV-FLDELDALAPRRGQSFDSGVSDRVVAALLTELDG---
MMAR_0752|M.marinum_M               FRRARDSAPSLV-FLDEVDALAPRRGQSFDSGVGDRVVAALLTELDG---
MUL_1384|M.ulcerans_Agy99           FRRARDSAPSLV-FLDEVDALAPRRGQSFDSGVGDRVVAALLTELDG---
MAV_4716|M.avium_104                FRRARDSAPALI-FLDEVDALAPRRGQSFDSGVTDRVVAALLTELDG---
Mflv_0155|M.gilvum_PYR-GCK          FQRARDSAPSLV-FLDEIDALAPRRGQSFDSGVTDRVVAAMLTELDG---
Mvan_0749|M.vanbaalenii_PYR-1       FRRARDSAPSLV-FLDEIDALAPRRGQSFDSGVTDRVVAALLTELDG---
TH_2865|M.thermoresistible__bu      FQRARASAPSLV-FLDEIDALAPRRGQSVDSGVTDRVVASLLTELDG---
MSMEG_0858|M.smegmatis_MC2_155      FARARDSAPSLV-FLDEIDALAPRRGQNFDSGVTDKVVASLLTELDG---
MAB_0637c|M.abscessus_ATCC_199      FRRARDSAPSLV-FLDEVDALAPRRGQSFDSGVTDRVVAALLTELDG---
MLBr_00222|M.leprae_Br4923          LTEYRDVLDTLAGELLEKETLHRPELEGIFASVEKRPRLTMFDDFGGRIP
                                    : . *    :*   * * ::*   . :.. :.* .:   ::: ::.*   

Mb0443c|M.bovis_AF2122/97           -----IDPLRDVVMLGATNRPDLIDPALLRPGRLERLVFVEPPDAAARRE
Rv0435c|M.tuberculosis_H37Rv        -----IDPLRDVVMLGATNRPDLIDPALLRPGRLERLVFVEPPDAAARRE
MMAR_0752|M.marinum_M               -----IEPLRDVVVLGATNRPDLIDPALLRPGRLERLVFVEPPDAEARLE
MUL_1384|M.ulcerans_Agy99           -----IEPLRDVVVLGATNRPDLIDPALLRPGRLERLVFVEPPDAEARLE
MAV_4716|M.avium_104                -----VDPLRDVVVLGATNRPDLIDPALLRPGRLERLVFVEPPDAAARRE
Mflv_0155|M.gilvum_PYR-GCK          -----IEPLRDVVVLGATNRPDLIDPALLRPGRLEKLVFVEPPDAEARTQ
Mvan_0749|M.vanbaalenii_PYR-1       -----IEPLVDVVVLGATNRPDLIDPALLRPGRLEKLVFVEPPDAEARTQ
TH_2865|M.thermoresistible__bu      -----IEPLRDVVVLGATNRPDLIDPALLRPGRLERLVFVEPPDAAARRE
MSMEG_0858|M.smegmatis_MC2_155      -----IEPLRDVVVLGATNRPDLIDPALLRPGRLERLVFVEPPDAAARRD
MAB_0637c|M.abscessus_ATCC_199      -----VEPLRDVVVLGATNRPELIDPALLRPGRMERLVFVEPPDAQARTD
MLBr_00222|M.leprae_Br4923          SDKPPIKTPGELAIERGEPWPQPVPEPAFKAAIARASQAAEASHQAAQSD
                                         :..  ::.:  .   *: :  . ::..  .    .*...  *: :

Mb0443c|M.bovis_AF2122/97           ILRTAGKSIPLSSD----VDLDEVAAGLDG-----------YSAADCVAL
Rv0435c|M.tuberculosis_H37Rv        ILRTAGKSIPLSSD----VDLDEVAAGLDG-----------YSAADCVAL
MMAR_0752|M.marinum_M               ILRTAGKSIPLSAD----VDLDEVAAGLDG-----------YSAADCVAL
MUL_1384|M.ulcerans_Agy99           ILRTAGKSIPLSAD----VDLDEVAAGLDG-----------YSAADCVAL
MAV_4716|M.avium_104                ILRTAGKSIPLSAD----VDLDELAAGLDG-----------YSAADCVAL
Mflv_0155|M.gilvum_PYR-GCK          ILRTAGKSVPLAAD----VDLEVLAADLDG-----------YSAADCVAL
Mvan_0749|M.vanbaalenii_PYR-1       ILKTAGKSVPLASDGPEAVDLETLSADLDG-----------YSAADCVAL
TH_2865|M.thermoresistible__bu      ILATAGKSIPLATEGPDAVDLDALAAELDG-----------YSAADCVAL
MSMEG_0858|M.smegmatis_MC2_155      ILRTAGKSIPLADD----VDLDSLADDLDG-----------YSAADCVAL
MAB_0637c|M.abscessus_ATCC_199      ILRTAARSVPLGAD----VDLNALAADLDG-----------FSAADCAAL
MLBr_00222|M.leprae_Br4923          TDGPPGQGANGSHAGDRQRQHGPTQPDYGAPPGWHAPGWPPQQPPDYWYP
                                       ...:.   .       :        ..            ...*    

Mb0443c|M.bovis_AF2122/97           LREAALTAMRRSIDAANVTAADLATAR-ETVRASLDPLQVASLRKFGTKG
Rv0435c|M.tuberculosis_H37Rv        LREAALTAMRRSIDAANVTAADLATAR-ETVRASLDPLQVASLRKFGTKG
MMAR_0752|M.marinum_M               LREAALTAMRRSIDAADVTAADLAAAR-QTVRPSLDPLQVDALRAFGEEL
MUL_1384|M.ulcerans_Agy99           LREAALTAMRRSIDAADVTAADLAAARRQTVRPSLDPLQVDALRAFGEEL
MAV_4716|M.avium_104                LREAALTAMRRSIDATDVTAADLAAAR-ENVRPSLDPAQVASLRAFAEAP
Mflv_0155|M.gilvum_PYR-GCK          LREAALTAMRRSIDAADVTADDVARAR-ETVRPSLDPAQVESLRQFADTR
Mvan_0749|M.vanbaalenii_PYR-1       LREAALTAMRRSIDAADVTASDVATAR-QTVRPSLDPVQVESLRAFAESR
TH_2865|M.thermoresistible__bu      LREAALTAMRRSIDAADVTAADVARAR-ETVRPSLDPAQVQALRAFAAGR
MSMEG_0858|M.smegmatis_MC2_155      LRESAMTAMRRSIDAADVTAADVAKAR-ETVRPSLDPAQVESLREFAEKR
MAB_0637c|M.abscessus_ATCC_199      LREAAMAAMRRSIDAADVTSADIHTAR-SVVRPSLDPVQVASLRAFADNR
MLBr_00222|M.leprae_Br4923          PEQQPSQSPYWPQPAPSYPGQAPPPYPSYPPCPSYPPPGQSAPDAGKPPA
                                     .: .  :   .  *.. ..            .*  *    :        

Mb0443c|M.bovis_AF2122/97           DLRS-----------
Rv0435c|M.tuberculosis_H37Rv        DLRS-----------
MMAR_0752|M.marinum_M               ---------------
MUL_1384|M.ulcerans_Agy99           ---------------
MAV_4716|M.avium_104                ---------------
Mflv_0155|M.gilvum_PYR-GCK          ---------------
Mvan_0749|M.vanbaalenii_PYR-1       ---------------
TH_2865|M.thermoresistible__bu      ---------------
MSMEG_0858|M.smegmatis_MC2_155      ---------------
MAB_0637c|M.abscessus_ATCC_199      ---------------
MLBr_00222|M.leprae_Br4923          QLDEGVSPSNPPAHG