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M. smegmatis MC2 155 MSMEG_0688 (-)

annotation: aminotransferase AlaT
coordinates: 771588 - 772862
length: 424

ERVTTHQLPWQSTGEHRKPRTFTQSTKLQDVLYEIRGPVHEHASRLEAEGHRILKLNIGNPAPFGFEAPD
VIMRDIIQALPTAQGYSDSKGILSARRAVFTRYELVEGFPKFDVDDVYLGNGVSELITMTLQALLDNGDQ
VLIPAPDYPLWTASTSLAGGTPVHYLCDETQGWNPDVADIESKITERTKAIVVINPNNPTGAVYSRETLE
QIVDLARKHQLLLLADEIYDKILYDDAKHISLATLAPDLLCLTFNGLSKAYRVAGYRSGWLVITGPKEHA
TSFIEGISLLANMRLCPNVPAQHAIQVALGGHQSIDALVLPGGRLLEQRDVAWEKLNEIPGVSCVKPRGA
LYAFPRLDPEVYDIHDDEQLVLDLLLQEKILLTQGTGFNWPTPDHLRIVTLPWARDLASAIERLGNFLAS
YRQ*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0688--100% (424)aminotransferase AlaT
M. smegmatis MC2 155MSMEG_6017-3e-1925.75% (369) aspartate aminotransferase
M. smegmatis MC2 155MSMEG_5725-3e-1929.17% (192) aminotransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0344caspC0.089.07% (421) aminotransferase AlaT
M. gilvum PYR-GCKMflv_0279-0.090.52% (422) aminotransferase AlaT
M. tuberculosis H37RvRv0337caspC0.089.07% (421) aminotransferase AlaT
M. leprae Br4923MLBr_02502-0.086.79% (424) aminotransferase AlaT
M. abscessus ATCC 19977MAB_4294-0.086.09% (417) aminotransferase AlaT
M. marinum MMMAR_0610aspC0.087.74% (424) aspartate aminotransferase AspC
M. avium 104MAV_4818-0.088.59% (412) aminotransferase AlaT
M. thermoresistible (build 8)TH_0764aspC0.088.17% (431) PROBABLE ASPARTATE AMINOTRANSFERASE ASPC (TRANSAMINASE A)
M. ulcerans Agy99MUL_0573aspC0.087.74% (424) aminotransferase AlaT
M. vanbaalenii PYR-1Mvan_0618-0.091.06% (425) aminotransferase AlaT

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_0610|M.marinum_M               --------MDSDETMVDVTTHQLPWHAS-SHQRQ-RSFAQSSKLQDVLYE
MUL_0573|M.ulcerans_Agy99           --------MDSDETMVDVTTHQLPWHAS-SHQRQ-RSFAQSSKLQDVLYE
Mb0344c|M.bovis_AF2122/97           --------MDNDGTIVDVTTHQLPWHTA-SHQRQ-RAFAQSAKLQDVLYE
Rv0337c|M.tuberculosis_H37Rv        --------MDNDGTIVDVTTHQLPWHTA-SHQRQ-RAFAQSAKLQDVLYE
MLBr_02502|M.leprae_Br4923          MTLYQQISVDGSGTMSDVTTHQLPMHTP-GYHRQ-RAFAQSSKLQDVLYE
MAV_4818|M.avium_104                ------------------------MHSS-AHHRQQRTFAQSSKLQDVLYE
MAB_4294|M.abscessus_ATCC_1997      --------MSTDNLPIDVPP-RVPGLSP-RQHQR--VFAQSTKLQDVLYE
MSMEG_0688|M.smegmatis_MC2_155      -----MERVTTHQLP----WQSTGEHR------KPRTFTQSTKLQDVLYE
TH_0764|M.thermoresistible__bu      --------VTSHQLPAEKTWQGYSAHGPHGHPSRPRTFAQSSKLQDVLYE
Mflv_0279|M.gilvum_PYR-GCK          --------MSTHQAH----WQAGTGQH-----ARQREFAQSSKLQDVLYE
Mvan_0618|M.vanbaalenii_PYR-1       -----MSLVSTHQAH----WHTGSGQH-----ARQREFTQSSKLQDVLYE
                                                                     :   *:**:********

MMAR_0610|M.marinum_M               IRGPVHQQAARLETEGHRILKLNIGNPAPFGFEAPDVIMRDMIQALPYAQ
MUL_0573|M.ulcerans_Agy99           IRGPVHQQAARLETEGHRILKLNIGNPAPFGFEAPDVIMRDMIQALPYAQ
Mb0344c|M.bovis_AF2122/97           IRGPVHQHAARLEAEGHRILKLNIGNPAPFGFEAPDVIMRDIIQALPYAQ
Rv0337c|M.tuberculosis_H37Rv        IRGPVHQHAARLEAEGHRILKLNIGNPAPFGFEAPDVIMRDIIQALPYAQ
MLBr_02502|M.leprae_Br4923          IRGPVSQHATRLETEGHRILKLNIGNPALFGFDAPDVIMRDMIQALPYAQ
MAV_4818|M.avium_104                IRGPVHQHAARLEAEGHRILKLNIGNPAPFGFEAPDVIMRDMIQALPYAQ
MAB_4294|M.abscessus_ATCC_1997      IRGPVHAHAARLEAEGHRILKLNIGNPAPFGFEAPDVIMRDIIQALPYAQ
MSMEG_0688|M.smegmatis_MC2_155      IRGPVHEHASRLEAEGHRILKLNIGNPAPFGFEAPDVIMRDIIQALPTAQ
TH_0764|M.thermoresistible__bu      IRGPVHDHAARLEMEGHRILKLNIGNPAPFGFEAPDVIMRDIIQALPYAQ
Mflv_0279|M.gilvum_PYR-GCK          IRGPVHEHASRLEAEGHRILKLNIGNPAPFGFEAPDVIMRDIIAALPYAQ
Mvan_0618|M.vanbaalenii_PYR-1       IRGPIHEHASRLEAEGHRIFKLNIGNPAPFGFEAPDVIMRDIIAALPYAQ
                                    ****:  :*:*** *****:******** ***:********:* *** **

MMAR_0610|M.marinum_M               GYSDSQGILPARRAVVTRYELVDGFPRFDVDDVYLGNGVSELITMTLQAL
MUL_0573|M.ulcerans_Agy99           GYSDSQGILPARRAVVTRYELVDGFPRFDVDDVYLGNGVSELITMTLQAL
Mb0344c|M.bovis_AF2122/97           GYSDSQGILSARRAVVTRYELVPGFPRFDVDDVYLGNGVSELITMTLQAL
Rv0337c|M.tuberculosis_H37Rv        GYSDSQGILSARRAVVTRYELVPGFPRFDVDDVYLGNGVSELITMTLQAL
MLBr_02502|M.leprae_Br4923          GYSDSQGILPARRAVVTRYELVDGFPRFDVDDVYLGNGVSELITMTLQAL
MAV_4818|M.avium_104                GYSDSQGILPARRAVVTRYELVDGFPRFDVDDVYLGNGVSELITMTLQAL
MAB_4294|M.abscessus_ATCC_1997      GYSDSKGILPARRAVVTRYELVDGFPYLDVDDVFLGNGVSELITMTTQAL
MSMEG_0688|M.smegmatis_MC2_155      GYSDSKGILSARRAVFTRYELVEGFPKFDVDDVYLGNGVSELITMTLQAL
TH_0764|M.thermoresistible__bu      GYSDSKGILPARRAVVTRYELVEGFPPFDVDDVYLGNGASELIQMTLQAL
Mflv_0279|M.gilvum_PYR-GCK          GYSDSKGIVSARRAVFTRYELVEGFPRFDIDDVFLGNGVSELIQMTLQAL
Mvan_0618|M.vanbaalenii_PYR-1       GYSDSKGIVSARRAVFTRYELVEGFPKFDIDDVFLGNGVSELITMTLQAL
                                    *****:**:.*****.****** *** :*:***:****.**** ** ***

MMAR_0610|M.marinum_M               LDNGDQVLIPAPDYPLWTASTSLAGGTPVHYLCDETQDWQPDIADLESKI
MUL_0573|M.ulcerans_Agy99           LDNGDQVLIPAPDYPLWTASTSLAGGTPVHYLCDETQDWQPDIADLESKI
Mb0344c|M.bovis_AF2122/97           LDNGDQVLIPSPDYPLWTASTSLAGGTPVHYLCDETQGWQPDIADLESKI
Rv0337c|M.tuberculosis_H37Rv        LDNGDQVLIPSPDYPLWTASTSLAGGTPVHYLCDETQGWQPDIADLESKI
MLBr_02502|M.leprae_Br4923          LDNGDQVLIPSPDYPLWTASTSLAGGTPVHYLCDETQGWQPDIADVESKI
MAV_4818|M.avium_104                LDNGDEVLIPSPDYPLWTASTSLAGGTPVHYLCDETQGWQPDIADLESKI
MAB_4294|M.abscessus_ATCC_1997      LDNGDQVLIPAPDYPLWTAATSLAGGTAVHYLCDETNGWMPDIEDLESKI
MSMEG_0688|M.smegmatis_MC2_155      LDNGDQVLIPAPDYPLWTASTSLAGGTPVHYLCDETQGWNPDVADIESKI
TH_0764|M.thermoresistible__bu      LDNGDQVLIPAPDYPLWTACTSLAGGTPVHYLCDETQGWNPDIEDLESKI
Mflv_0279|M.gilvum_PYR-GCK          LDNGDQVLIPAPDYPLWTACTSLAGGTPVHYLCDETQGWNPDVADIESKI
Mvan_0618|M.vanbaalenii_PYR-1       LDNGDQVLIPAPDYPLWTASTALAGGTPVHYLCDETQGWNPDIADLESKI
                                    *****:****:********.*:*****.********:.* **: *:****

MMAR_0610|M.marinum_M               TERTKALVIINPNNPTGAVYSHEILTQMVELARKHELLLLADEIYDKILY
MUL_0573|M.ulcerans_Agy99           TERTKALVIINPNNPTGAVYSHEILTQMVELARKHELLLLADEIYDKILY
Mb0344c|M.bovis_AF2122/97           TERTKALVVINPNNPTGAVYSCEILTQMVDLARKHQLLLLADEIYDKILY
Rv0337c|M.tuberculosis_H37Rv        TERTKALVVINPNNPTGAVYSCEILTQMVDLARKHQLLLLADEIYDKILY
MLBr_02502|M.leprae_Br4923          TERTKALVVINPNNPTGAVYSNEILNQIVDLARKHQLLLLADEIYDKILY
MAV_4818|M.avium_104                TERTKALVVINPNNPTGAVYSGEILSQMVDLARKHELLLLADEIYDKILY
MAB_4294|M.abscessus_ATCC_1997      TERTKALVIINPNNPTGAVYSREILTKMVELARKHQLLLLADEIYDKILY
MSMEG_0688|M.smegmatis_MC2_155      TERTKAIVVINPNNPTGAVYSRETLEQIVDLARKHQLLLLADEIYDKILY
TH_0764|M.thermoresistible__bu      TERTKAIVVINPNNPTGAVYTRETLEQIAELARRHQLLLLADEIYDKILY
Mflv_0279|M.gilvum_PYR-GCK          TDRTKAIVVINPNNPTGAVYSREVLTQIADLARKHQLLLLADEIYDKILY
Mvan_0618|M.vanbaalenii_PYR-1       TERTKALVVINPNNPTGAVYSRETLEQMVELARKHQLLLLADEIYDKILY
                                    *:****:*:***********: * * ::.:***:*:**************

MMAR_0610|M.marinum_M               DDAKHISVATLAPDMLCLTFNGLSKAYRVAGYRAGWLAITGPKEHASSFI
MUL_0573|M.ulcerans_Agy99           DDAKHISVATLAPDMLCLTFNGLSKAYRVAGYRAGWLAITGPKEHASSFI
Mb0344c|M.bovis_AF2122/97           DDAKHISLASIAPDMLCLTFNGLSKAYRVAGYRAGWLAITGPKEHASSFI
Rv0337c|M.tuberculosis_H37Rv        DDAKHISLASIAPDMLCLTFNGLSKAYRVAGYRAGWLAITGPKEHASSFI
MLBr_02502|M.leprae_Br4923          DDTKHISVASIAPDLLCLTFNGLSKAYRVAGYRSGWLAITGPKDHASSFI
MAV_4818|M.avium_104                DAAKHINVASLAPDMLCLTFNGLSKAYRVAGYRAGWLAITGPKDHAGSFI
MAB_4294|M.abscessus_ATCC_1997      DDAEHISVASLAPDLLCFTFNGLSKAYRVAGYRSAWLAITGPKDHAASLL
MSMEG_0688|M.smegmatis_MC2_155      DDAKHISLATLAPDLLCLTFNGLSKAYRVAGYRSGWLVITGPKEHATSFI
TH_0764|M.thermoresistible__bu      DDAKHISMAAVAPDVLTLTFNGLSKAYRVAGYRSGWLCITGPKEHAASFI
Mflv_0279|M.gilvum_PYR-GCK          DDAEHISLASVAPDLLTLTFNGLSKAYRVAGYRSGWLVITGPKEHAASFI
Mvan_0618|M.vanbaalenii_PYR-1       DDAKHISLATLAPDLLTLTFNGLSKAYRVAGYRSGWLVITGPKEHAASFI
                                    * ::**.:*::***:* :***************:.** *****:** *::

MMAR_0610|M.marinum_M               EGISLLANMRLCPNVPAQHAIQVALGGHQSIDDLVLPGGRLLEQRDVAWS
MUL_0573|M.ulcerans_Agy99           EGISLLANMRLCPNVPAQHAIQVALGGHQSIDDLVLPGGRLLEQRDVAWS
Mb0344c|M.bovis_AF2122/97           EGIGLLANMRLCPNVPAQHAIQVALGGHQSIEDLVLPGGRLLEQRDIAWT
Rv0337c|M.tuberculosis_H37Rv        EGIGLLANMRLCPNVPAQHAIQVALGGHQSIEDLVLPGGRLLEQRDIAWT
MLBr_02502|M.leprae_Br4923          GGINLLANMRLCPNVPAQHAIQVALGGHQSIEDLVLPGGRLLEQRDVAWT
MAV_4818|M.avium_104                EGINLLANMRLCPNVPAQHAIQVALGGHQSIEDLVLPGGRLLEQRDVAWS
MAB_4294|M.abscessus_ATCC_1997      EGVNLLANMRLCPNVPAQHAIQVALGGHQSIEDLVLPGGRLLEQRDVAWT
MSMEG_0688|M.smegmatis_MC2_155      EGISLLANMRLCPNVPAQHAIQVALGGHQSIDALVLPGGRLLEQRDVAWE
TH_0764|M.thermoresistible__bu      EGISLLANMRLCPNVPAQHAIQVALGGHQSIEELVLPGGRLREQRDVAWE
Mflv_0279|M.gilvum_PYR-GCK          EGISLLANMRLCPNVPAQHAIQVALGGHQSIDDLVLPGGRLLEQRDIAWE
Mvan_0618|M.vanbaalenii_PYR-1       EGINLLANMRLCPNVPAQHAIQVALGGHQSIDDLVLPGGRLLEQRDVAWE
                                     *:.***************************: ******** ****:** 

MMAR_0610|M.marinum_M               KLNEIPGVSCVKPKGALYAFPRLDPEVYDIADDEQLVLDLLLSEKILVTQ
MUL_0573|M.ulcerans_Agy99           KLNEIPGVSCVKPKGALYAFPRLDPEVYDIADDEQLVLDLLLSEKILVTQ
Mb0344c|M.bovis_AF2122/97           KLNEIPGVSCVKPAGALYAFPRLDPEVYDIDDDEQLVLDLLLSEKILVTQ
Rv0337c|M.tuberculosis_H37Rv        KLNEIPGVSCVKPAGALYAFPRLDPEVYDIDDDEQLVLDLLLSEKILVTQ
MLBr_02502|M.leprae_Br4923          KLNEIPGVSCVKPTGALYAFPRLDPEVYGIVDDEQLVLDLLLQEKILVTQ
MAV_4818|M.avium_104                KLNEIPGVSCVKPAGALYAFPRLDPEVYDITDDEQLVLDLLLQEKILVTQ
MAB_4294|M.abscessus_ATCC_1997      KLNEIPGVSCVKPQGALYAFPRLDPEVHHIHDDDQLVLDLLLNEKILLTQ
MSMEG_0688|M.smegmatis_MC2_155      KLNEIPGVSCVKPRGALYAFPRLDPEVYDIHDDEQLVLDLLLQEKILLTQ
TH_0764|M.thermoresistible__bu      KLNEIPGVSCVKPQGALYVFPRLDPEVYEIHDDEQLVLDLLLQEKILLTQ
Mflv_0279|M.gilvum_PYR-GCK          TLNEIPGVSCVKPQGALYAFPRLDPEVYDIADDEQLVLDLLLQEKILVVQ
Mvan_0618|M.vanbaalenii_PYR-1       KLNEIPGVSCVKPKGALYAFPRLDPEVYDVEDDEQLVLDLLLQEKILLTQ
                                    .************ ****.********: : **:********.****:.*

MMAR_0610|M.marinum_M               GTGFNWPEPDHLRLVTLPWSRDLAAAIERLGNFLVSYRQ-
MUL_0573|M.ulcerans_Agy99           GTGFNWPEPDHLRLVTLPWSRDLAAAIERLGNFLVSYRQ-
Mb0344c|M.bovis_AF2122/97           GTGFNWPAPDHLRLVTLPWSRDLAAAIERLGNFLVSYRQ-
Rv0337c|M.tuberculosis_H37Rv        GTGFNWPAPDHLRLVTLPWSRDLAAAIERLGNFLVSYRQ-
MLBr_02502|M.leprae_Br4923          GSGFNWPAPDHLRLVTLPWSRDLAAAIDRLGNFLVSYRQ-
MAV_4818|M.avium_104                GTGFNWPAPDHLRIVTLPWARDLAAAIERLGNFLVGYRQ-
MAB_4294|M.abscessus_ATCC_1997      GTGFNWPEPDHLRIVTLPWARDLAVAIERLGNFLASYRQ-
MSMEG_0688|M.smegmatis_MC2_155      GTGFNWPTPDHLRIVTLPWARDLASAIERLGNFLASYRQ-
TH_0764|M.thermoresistible__bu      GTGFNWPTPDHLRIVTLPWARDLANAIERLGNFLVSYRQ-
Mflv_0279|M.gilvum_PYR-GCK          GTGFNWPTPDHLRIVTLPWARDLSAAIERLGNFLVSYRQ-
Mvan_0618|M.vanbaalenii_PYR-1       GTGFNWPTPDHLRIVTLPWSRDLAAAIERLGNFLVSYRQQ
                                    *:***** *****:*****:***: **:******..***