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TSERLGEFLRARRAQLNPEDVGLRDFGGRRRVAGLRREELAQLAGVSVSYYTRLEQGQAVNASDAVLDAL ADALQLNVHERKHLRDLATQRAQPVRKPPAERVSPLTRDLLRALGDVPAMVVGRRTDVLAWNEAGHALLA GHVDREAVERPAERPNLARMMFLDPHTRELYADWPRKARAVVGNLRYVAGRHPEDALLAALIGELTVKSE EFVTLWADHRVKRCEADTYDLRHPIVGPVTITQQNLVVARSPEQSLCIITTAAGSASEDAMKLLIRASRS GQRHPAPQRA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0609 | - | - | 100% (291) | helix-turn-helix domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_0523 | - | 7e-66 | 51.77% (282) | DNA-binding protein |
| M. smegmatis MC2 155 | MSMEG_1626 | - | 9e-56 | 45.30% (287) | putative DNA-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_5170 | - | 2e-30 | 32.47% (271) | XRE family transcriptional regulator |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4641 | - | 1e-33 | 35.44% (285) | putative DNA-binding protein |
| M. marinum M | MMAR_3947 | - | 2e-07 | 30.38% (158) | transcriptional regulatory protein |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_5465 | - | 1e-50 | 44.04% (277) | XRE family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5170|M.gilvum_PYR-GCK -MDTRAQRRLALGEFLRARREAIRRADVGLPELPR-ARTGGLRREEVAVT
MAB_4641|M.abscessus_ATCC_1997 -MAGTDERRRELGAFLRVRREHLVRADYGLPPVGR-SRTTGLRREEIAYL
MSMEG_0609|M.smegmatis_MC2_155 MTS------ERLGEFLRARRAQLNPEDVGLRDFGGRRRVAGLRREELAQL
Mvan_5465|M.vanbaalenii_PYR-1 MMANVADANRELADFLKRARSAVDPARAGLPADGRIRRVPGLRREEVALL
MMAR_3947|M.marinum_M --------MPNRGGFVHAARER-----------------AGLTCRELAEK
. *:: * ** .*:*
Mflv_5170|M.gilvum_PYR-GCK AGVSVTWYTWLEQGRDINPSKQVLDAVADALRLSPAEHEYVLALGGYA--
MAB_4641|M.abscessus_ATCC_1997 SGVSVTWYTWLEQGRDINPSRQVLEAIALEMRLSAAERTYLLELAGFAPL
MSMEG_0609|M.smegmatis_MC2_155 AGVSVSYYTRLEQGQAVNASDAVLDALADALQLNVHERKHLRDLATQRAQ
Mvan_5465|M.vanbaalenii_PYR-1 AGVSTDYYARLEQGRRITPSAAVLDAIARALDLGDTGRAHLGRLVGASPT
MMAR_3947|M.marinum_M AGCSLRYVHDIEQG--CSPSIRVLNGLVRALQLSAWEQRFLFAACGRI--
:* * : :*** ..* **:.:. : *. : .:
Mflv_5170|M.gilvum_PYR-GCK -VDAAVSRGPLPPHIQHFLDALEGYPAFAITPDWGIAAWNTTYAALYPN-
MAB_4641|M.abscessus_ATCC_1997 PHSATPDPAPVPDHLLRLVENLVPSPAFVVSADWSIGGWNRAYELLYPG-
MSMEG_0609|M.smegmatis_MC2_155 PVRKP-PAERVSPLTRDLLRALGDVPAMVVGRRTDVLAWNEAGHALLAGH
Mvan_5465|M.vanbaalenii_PYR-1 RRRSSRPVQRVRPGLYQLLDSLDETPAMILGRRTDVLATNRAARVLFA--
MMAR_3947|M.marinum_M ---LPDPALTDTDISQRYLDALQPHPAAALHPSWRFKAWNQQWQRLFQG-
. : * ** : . . * *
Mflv_5170|M.gilvum_PYR-GCK ----VERVPETDRNLLWLVFTDPYIHELLPNWDTDSRRFLAEFRADAGPR
MAB_4641|M.abscessus_ATCC_1997 ----IASIVPADRNLLRFIFTDPYVRQMLPDWPITSRRFLAEYRAEAGAL
MSMEG_0609|M.smegmatis_MC2_155 VDREAVERPAERPNLARMMFLDPHTRELYADWPRKARAVVGNLRYVAGRH
Mvan_5465|M.vanbaalenii_PYR-1 -DFDAMP-PRER-NYARWMFTSEQARNLFADWSVQARTAVENLRLDFGGD
MMAR_3947|M.marinum_M --------VLLAPSMHQWLYLSTTSRRILRNWDEVSQWCVGWLRYGLAVD
. :: . :.: :* :: : * .
Mflv_5170|M.gilvum_PYR-GCK VGEPSYTALVSRLSSESPHFAAAWQATSIERFTSRERLFRHPAAGELRLE
MAB_4641|M.abscessus_ATCC_1997 LGDPRHRALVDRLQQQSPEFARAWAEHEVGRFTSRERRFHHPEAGELIFE
MSMEG_0609|M.smegmatis_MC2_155 PEDALLAALIGELTVKSEEFVTLWADHRVKRCEADTYDLRHPIVGPVTIT
Mvan_5465|M.vanbaalenii_PYR-1 PHDPAVIELVDELSAASAEFRMWWAEHRVFQRTYGTKRLRHPVVGDLSVD
MMAR_3947|M.marinum_M VD--AVKPMVSALMPVT-EFRREWEAQVIPVDPATRLWVVRDGGTELRID
::. * : .* * : . : : .
Mflv_5170|M.gilvum_PYR-GCK HHQVAPVDVPDIQIVAYLPVPDSVASERLRMLTGQADTAR--------
MAB_4641|M.abscessus_ATCC_1997 HHRLSPSDLPDLHIVIYLPLDGTNTRTKLEALLSGGR-----------
MSMEG_0609|M.smegmatis_MC2_155 QQNLVVARSPEQSLCIITTAAGSASEDAMKLLIRASRSGQRHPAPQRA
Mvan_5465|M.vanbaalenii_PYR-1 YETFTMPGDAEQTLFVYLAEAGSPSRDALNLLLSWSANSV--------
MMAR_3947|M.marinum_M MRFWHASPMPGGLLLGVILDAG--------------------------
. . : .