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M. smegmatis MC2 155 MSMEG_0476 (-)

annotation: chitin synthase
coordinates: 554422 - 555717
length: 431

VATIAAADRTVTSVRPAELGVKVVIVMALLLIVMLIFAYKVVSLHNMKDEPFWAAYGLIITAFIFTRFGL
AALYRPPRRDTGNYWPVVAIIVPAYNEPDIARTLLHCVGVDYPRELLRVVVVDDKSSDDTLRRITDFAAE
HPNLTVIPHEVNGGKRRAMATGMAAADDADLFVFIDSDSQVTRDAIRVIASYFADSSVGAVCGHTDVTNI
SHNILTRMQAMQYYIAFRIYKSAEALFGSVTCCSGCFSAYRADAVRPVADKWLNQTFLGRPSTFGDDRSL
TNYLLRDWRVLYAPDAQAYTNVPEHLKQFLRQQLRWKKSWLREAPRAMCAVRRKNPVMVVMFALSIVLPL
IAPQVVMRAFVVQPHFISQLPFWYFGGVAAIAVIYGLFYRLHRPVKRWYQGIFFTMFYTIILVLQMPYAM
VTIRDSKWGTR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0476--100% (431)chitin synthase
M. smegmatis MC2 155MSMEG_1426-6e-0724.42% (172) membrane sugar transferase
M. smegmatis MC2 155MSMEG_5961-2e-0628.57% (133) glycosyl transferase, group 2 family protein, putative

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0715-8e-0727.74% (155) membrane sugar transferase
M. gilvum PYR-GCKMflv_0207-8e-1024.70% (247) hypothetical protein Mflv_0207
M. tuberculosis H37RvRv0696-8e-0727.74% (155) membrane sugar transferase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3831c-7e-0723.28% (189) putative glycosyltransferase
M. marinum MMMAR_1024-2e-0828.10% (153) membrane glycosyl transferase
M. avium 104MAV_4475-1e-0728.95% (152) membrane sugar transferase
M. thermoresistible (build 8)TH_1903-5e-0625.60% (125) PROBABLE MEMBRANE SUGAR TRANSFERASE
M. ulcerans Agy99MUL_0776-4e-0832.08% (106) membrane glycosyl transferase
M. vanbaalenii PYR-1Mvan_1299-1e-0728.80% (125) glycosyl transferase family protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_1903|M.thermoresistible__bu      ------------MTGQRLPDGFAVQ-VDRRVKVLGEGAALLGGSPTRLLK
Mvan_1299|M.vanbaalenii_PYR-1       ------------MTGPRLPDGFAVQ-VDRRVRVLGEGAALLGGSPTRLLR
Mb0715|M.bovis_AF2122/97            ------------MTATRLPDGFAVQ-VDRRVRVLGDGSALLGGSPTRLLR
Rv0696|M.tuberculosis_H37Rv         ------------MTATRLPDGFAVQ-VDRRVRVLGDGSALLGGSPTRLLR
MMAR_1024|M.marinum_M               ------------MTQPRLPDGFAVQ-VDRRVRVLGGGSALLGGSPTRLLR
MUL_0776|M.ulcerans_Agy99           ------------MTQPRLPDGFAVQ-VDRRVRVLGGGSALLGGSPTRLLR
MAV_4475|M.avium_104                ----------MTAPAPRLPDGFAVQ-VDRRVRVLGDGSALLGGSPTRLLK
MAB_3831c|M.abscessus_ATCC_199      MTTSDEQAQHAAPSQERLPDGFAVQ-VDRRVRVLDEGSALLGGSPTRLLR
Mflv_0207|M.gilvum_PYR-GCK          --------MHSYTPGSRLPEDLSARRVTTDGSVILGVSGILGVAATGVLA
MSMEG_0476|M.smegmatis_MC2_155      ----------MATIAAADRTVTSVRPAELGVKVVIVMALLLIVMLIFAYK
                                                          :.: .     *:   : :*         

TH_1903|M.thermoresistible__bu      ---LAPAARTMLAGGRLEVRDAVSAQLAR-----TLLDATVAHPRPASGP
Mvan_1299|M.vanbaalenii_PYR-1       ---LAPAAQTMLHGGRLEVHDAVSAQLAR-----TLLDATVAHPRPMSGP
Mb0715|M.bovis_AF2122/97            ---LAPAARGLLCDGRLKVRDEVSAELAR-----ILLDATVAHPRPPSGP
Rv0696|M.tuberculosis_H37Rv         ---LAPAARGLLCDGRLKVRDEVSAELAR-----ILLDATVAHPRPPSGP
MMAR_1024|M.marinum_M               ---LAPAAQDMLCDGRLKVRDDISAELAR-----TLLDATVAHPRPASGP
MUL_0776|M.ulcerans_Agy99           ---LAPAAQDMLCDGRLKVRDDISAELAR-----TLLDATVAHPRPASGP
MAV_4475|M.avium_104                ---LAPAAQDLLCDGRLKVRDDVSAQLAR-----TLLDATVAHPRPAGGP
MAB_3831c|M.abscessus_ATCC_199      ---LAPAARTLLSGGRLEVRDATSAQLAR-----TLLDATVAHPRPVGGP
Mflv_0207|M.gilvum_PYR-GCK          PHLVLPAVTTVLAALYLASTIDRHWLLVQGLRSPSLLTISDEEARAVPDN
MSMEG_0476|M.smegmatis_MC2_155      VVSLHNMKDEPFWAAYGLIITAFIFTRFG-------LAALYRPPRRDTGN
                                       :       :                        *      .*   . 

TH_1903|M.thermoresistible__bu      SHRDVTVVIPVRDNAFGLHRLMRALRGLR--------VIIVDD---GSAV
Mvan_1299|M.vanbaalenii_PYR-1       SHRDVTVIIPVRDNLSGLTRLVSALRGLR--------VVVVDD---GSAV
Mb0715|M.bovis_AF2122/97            SHRDVTVVIPVRNNASGLRRLVTSLRGLR--------VIVVDD---GSAC
Rv0696|M.tuberculosis_H37Rv         SHRDVTVVIPVRNNASGLRRLVTSLRGLR--------VIVVDD---GSAC
MMAR_1024|M.marinum_M               SHRDVTVVIPVRDNASGVRRLVASLRGLR--------VIVVDD---GSSS
MUL_0776|M.ulcerans_Agy99           SHRDVTVVISVRDNASGVRRLVASLRGLR--------VIVVDD---GSSS
MAV_4475|M.avium_104                SHHDVTVVIPVRDNLSGVRRLVSSLRGLR--------VVVVDD---GSFP
MAB_3831c|M.abscessus_ATCC_199      GYRDVTVVIPCRDNGFGLRRLLRALRGMR--------VIVVDD---GSTI
Mflv_0207|M.gilvum_PYR-GCK          QLPVYTVLLPVYNEPSIVHNLIAGVGRLEYPKDKLEILLLVEEDDIATRR
MSMEG_0476|M.smegmatis_MC2_155      YWPVVAIIVPAYNEPDIARTLLHCVGVDYPR--ELLRVVVVDDKS-SDDT
                                         ::::.  ::      *:  :            :::*::   .   

TH_1903|M.thermoresistible__bu      PVDAAEFTGLHCDVQVLRHPHSKGPAAARNTGLAACT-TDFVAFLDSDVV
Mvan_1299|M.vanbaalenii_PYR-1       PVAESDFAATRCDVQVLRNDRSKGPAAARNAGLAVCT-TDLVAFLDSDVL
Mb0715|M.bovis_AF2122/97            PVESDDFVGAHCDIEVLHHPHSKGPAAARNTGLAACT-TDFVAFLDSDVT
Rv0696|M.tuberculosis_H37Rv         PVESDDFVGAHCDIEVLHHPHSKGPAAARNTGLAACT-TDFVAFLDSDVT
MMAR_1024|M.marinum_M               PVELEDFAGAHCDVEVLHHRRSKGPAAARNTGLAACT-TEFVAFLDSDVA
MUL_0776|M.ulcerans_Agy99           PVELEDFAGAHCDIEVLHHRRSKGPAAARNTGLAACT-TEFVAFLDSDVA
MAV_4475|M.avium_104                PIEPEDFVGAHCDIEVLRHHRSKGPAAARNTGLAACR-TDFVAFLDSDVA
MAB_3831c|M.abscessus_ATCC_199      PIVESDLEGMHCHVEVVRHADSQGPAAARNTGLKLAT-TDFVAFLDSDVV
Mflv_0207|M.gilvum_PYR-GCK          AMATTELEAVRLILVPNSQPKTKPKACNYGMATPGLK-GEMVTIYDAEDI
MSMEG_0476|M.smegmatis_MC2_155      LRRITDFAAEHPNLTVIPHEVNGGKRRAMATGMAAADDADLFVFIDSDSQ
                                         :: . :  :    :  .         .       ::..: *::  

TH_1903|M.thermoresistible__bu      PQRGWLEALLGHFCDP--AVALVAPRIVGLRKDDNLIARYEAVRSSLDLG
Mvan_1299|M.vanbaalenii_PYR-1       PRRGWLEALLGHFCDP--AVALVAPRIVALNQSDNVVARYEAVRSSLDLG
Mb0715|M.bovis_AF2122/97            PRRGWLESLLGHFCDP--TVALVAPRIVSLVEGENPVARYEALHSSLDLG
Rv0696|M.tuberculosis_H37Rv         PRRGWLESLLGHFCDP--TVALVAPRIVSLVEGENPVARYEALHSSLDLG
MMAR_1024|M.marinum_M               PRRGWLEALLGHFCDP--TVALVAPRIVGLAPSENLVARYEAVRSSLDLG
MUL_0776|M.ulcerans_Agy99           PRRGWLEALLGHFCDP--TVALVAPRIVGLAPSENLVARYEAVRSSLDLG
MAV_4475|M.avium_104                PRRGWLEALLGHFCDP--TVGLVAPRIVGLSHSENVVARYEAVHSSLDLG
MAB_3831c|M.abscessus_ATCC_199      PRRGWLEALLGHFSDP--AVALVAPRIVGLVLSDNAIARYEAVRSSLDLG
Mflv_0207|M.gilvum_PYR-GCK          PDPLQLRKTVVAFQQLPDNVGCIQARLGYFNEEQNLLTRWFSMEYDQWFG
MSMEG_0476|M.smegmatis_MC2_155      VTRDAIRVIASYFADS--SVGAVCGHTDVTNISHNILTRMQAMQYYIAFR
                                         :.     * :    *. :  :       .* ::*  ::.    : 

TH_1903|M.thermoresistible__bu      VREAPVVPYGPVSYVPSAAIICRRKVLDEIGGFDEALRSGEDVDLCWRLV
Mvan_1299|M.vanbaalenii_PYR-1       LREAPVIPYGTVSYVPSAAIICRRSRLLEVGGFDESLISGEDVDLCWRLN
Mb0715|M.bovis_AF2122/97            QREAPVLPHSTVSYVPSAAIVCRSSAIRDVGGFDETMHSGEDVDLCWRLI
Rv0696|M.tuberculosis_H37Rv         QREAPVLPHSTVSYVPSAAIVCRSSAIRDVGGFDETMHSGEDVDLCWRLI
MMAR_1024|M.marinum_M               QREAPILPHSPVSYVPSAAIICRCSAIRQVGGFDETMHSGEDVDLCWRLI
MUL_0776|M.ulcerans_Agy99           QREAPILPHSPVSYVPSAAIICRCSAIRQVGGFDETMHSGEDVDLCWRLI
MAV_4475|M.avium_104                EREAPVLPHSTVSYVPSAAIICRCSAIREIGGFDETLQSGEDVDLCWRLI
MAB_3831c|M.abscessus_ATCC_199      LREAPVVPYGPVSYVPSAAIVVRRSAINEIGGFDEALQCGEDVDLCWRLI
Mflv_0207|M.gilvum_PYR-GCK          MTLPAVEAAGCVVPLGGTSNHMRTSVWRAIGGWDEFN-VTEDADLGVRLA
MSMEG_0476|M.smegmatis_MC2_155      IYKSAEALFGSVTCCSGCFSAYRADAVRPVA----------DKWLNQTFL
                                       ..    . *    .     * .    :.          *  *   : 

TH_1903|M.thermoresistible__bu      EAGTRLRYEPIALVAHDHRTDIGEWLGRKAFYGSSAAPLTARHPDKTAPL
Mvan_1299|M.vanbaalenii_PYR-1       EAGARLRYEPIAMVAHDHRTELRKWFARKSFYGSSAAPLTIRHPGKTAPL
Mb0715|M.bovis_AF2122/97            EAGARLRYEPIALVAHDHRTQLRDWIARKAFYGGSAAPLAVRHPDKTAPL
Rv0696|M.tuberculosis_H37Rv         EAGARLRYEPIALVAHDHRTQLRDWIARKAFYGGSAAPLAVRHPDKTAPL
MMAR_1024|M.marinum_M               ESGARLRYEPIALVGHEHRTQLRAWIARKAFYGGSAAPLSVRHPDKTAPL
MUL_0776|M.ulcerans_Agy99           ESGARLRYEPIALVGHEHRTQLRAWIARKAFYGGSAAPLSVRHPDKTAPL
MAV_4475|M.avium_104                EAGVRLRYEPIALVGHDHRTELRDWLARKAFYGGSAAPLSVRHPDKTAPV
MAB_3831c|M.abscessus_ATCC_199      EAGSRLRYEPVSHVAHDHRLTLREWFARKAFYGKSAAPLSTRHPDKVAPM
Mflv_0207|M.gilvum_PYR-GCK          RAGYRTRILDSVTLEEANSDVLNWIRQRSRWYKGYLQTMLVHLRHPAALW
MSMEG_0476|M.smegmatis_MC2_155      GR--------PSTFGDDRSLTNYLLRDWRVLYAPDAQAYTNVPEHLKQFL
                                                 . . .             *     .            

TH_1903|M.thermoresistible__bu      LMSGWTLVLGVLVAMGSWVGYLAALVLAVITGRRVAKSLSTVGSEPVEVV
Mvan_1299|M.vanbaalenii_PYR-1       VISGWTLVVWMLVAIGSGIGYFASIAVAAITGRRIAKSLASVQTEPMEVA
Mb0715|M.bovis_AF2122/97            VISGGALMAWILMSIGTGLGRLASLVIAVLTGRRIARAMRCAETSFLDVL
Rv0696|M.tuberculosis_H37Rv         VISGGALMAWILMSIGTGLGRLASLVIAVLTGRRIARAMRCAETSFLDVL
MMAR_1024|M.marinum_M               VISGWALTAWVLMSLGTRATQLASLIIAVLTGRRIATALRSAQTSSWDVV
MUL_0776|M.ulcerans_Agy99           VISGWALTAWVLLSLGTRATQLASLIIAVLTGRRIATALRSAQTSSWDVV
MAV_4475|M.avium_104                VISGWALMTWILMAFGSTLSRLASLLLAVLTGRRIARAMRSAETSMTDVV
MAB_3831c|M.abscessus_ATCC_199      VISRWTLLVWILAAVGSGMGYLAAVGMAALAAGRVARTLRGVDTPPRDVV
Mflv_0207|M.gilvum_PYR-GCK          SQVGGKGILRLLNMTG-------AVPIVAVINLVFWATMAAWVLGRPDVV
MSMEG_0476|M.smegmatis_MC2_155      RQQLRWKKSWLREAPR-------AMCAVRRKNPVMVVMFALSIVLPLIAP
                                              :            ::  .      .   :         . 

TH_1903|M.thermoresistible__bu      ALAAQGLGSAARQLAGAICRHYWPIALIAALLSPRFRQVVVVAAVVDGVV
Mvan_1299|M.vanbaalenii_PYR-1       VVAAHGLGSAALQLASAICRHYWPIALIAALVSRRSRRVVVVAAVLDGVF
Mb0715|M.bovis_AF2122/97            AVATRGLWAAALQLASAICRHYWPLALLAAILSRRCRRVVLIAAVVDGVV
Rv0696|M.tuberculosis_H37Rv         AVATRGLWAAALQLASAICRHYWPLALLAAILSRRCRRVVLIAAVVDGVV
MMAR_1024|M.marinum_M               VVAARGLWSAALQLASAICRHYWPVTLIAVIVSRHCRRVVLVAAVIDGVV
MUL_0776|M.ulcerans_Agy99           VVAARGLWSAALQLASAICRHYWPVTLIAVIVSRHCRRVVLVAAVIDGVV
MAV_4475|M.avium_104                TVAGRGLWSAALQLASALCRHYWPLALLAATMSRHFRRVVLVAAVMDGVV
MAB_3831c|M.abscessus_ATCC_199      RVAAQGVGGAALQIASALCRHYWPLALFAAALSRRSRQVLVVAAIVDGVV
Mflv_0207|M.gilvum_PYR-GCK          ELAFPGATYYVYLTMYVVGAPLS--VFMGLIVTQRLGKPYMWWAAALVPL
MSMEG_0476|M.smegmatis_MC2_155      QVVMRAFVVQPHFISQLPFWYFGGVAAIAVIYG-------LFYRLHRPVK
                                     :.  .                   . :.           :         

TH_1903|M.thermoresistible__bu      DWLSRREHAGEDTKPVGLFAYLVLKRLDDLAYGCGLWAGVLRERDLGALK
Mvan_1299|M.vanbaalenii_PYR-1       DWVTRNGNADEDTKRVGLPTYLLLKRLDDIAYGLGLWTGVVRERHAGALK
Mb0715|M.bovis_AF2122/97            DWLRRREGADDDAEPIGPLTYLVLKRVDDLAYGAGLWYGVVRERNIGALK
Rv0696|M.tuberculosis_H37Rv         DWLRRREGADDDAEPIGPLTYLVLKRVDDLAYGAGLWYGVVRERNIGALK
MMAR_1024|M.marinum_M               DWLRRREDPDGDSEPIGLLTYLLLKRIDDLAYGLGLWYGVMRERNAGALK
MUL_0776|M.ulcerans_Agy99           DWLRRREDPDGDSEPIGLLTYLLLKRIDDLAYGLGLWYGVMRERNAGALK
MAV_4475|M.avium_104                DWLRRRDAVGDDVEPIGLPTYLVLKRVDDLAYGLGLWWGVLRERNARALR
MAB_3831c|M.abscessus_ATCC_199      DWMKRNDSSASPDDRIGLIEYVLLKRLDDIAYGIGLWSGIVRERDLGALR
Mflv_0207|M.gilvum_PYR-GCK          YWMLQSIAALKAVFQLVTRPQFWEKTVHGLSDTVDVPNSTGRPT------
MSMEG_0476|M.smegmatis_MC2_155      RWYQGIFFTMFYTIILVLQMPYAMVTIRDSKWGTR---------------
                                     *             :          : .                     

TH_1903|M.thermoresistible__bu      PQIRI
Mvan_1299|M.vanbaalenii_PYR-1       PQIRT
Mb0715|M.bovis_AF2122/97            PQIRT
Rv0696|M.tuberculosis_H37Rv         PQIRT
MMAR_1024|M.marinum_M               PQIRR
MUL_0776|M.ulcerans_Agy99           PQIRR
MAV_4475|M.avium_104                PQIRS
MAB_3831c|M.abscessus_ATCC_199      PELRP
Mflv_0207|M.gilvum_PYR-GCK          -----
MSMEG_0476|M.smegmatis_MC2_155      -----