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RAWPGISAVVVTASVVLAGCGTEPQTTEPTAQPSRSSSQTTAEHPAGAAELTPVTVEVPEGLDDAPLDQP RQALVPDGWTLEVVARVPKARMAAWAPDGALLVSVPSTGEVLKVLPTQSTLLDGLDQPHGLFFAGPTLYV AESDQIDAYDYADGAAVNRRTVIDGLPDAKSPDLRGAYAHALKSVVVGDDGAVYFSIGSTGNISAEDRTA DPPRATIMRVPPGGGPAEPFATGVRNGTGLAFAPDGSLWTAVNNRDNVADPDGRVVQSYVDDHPPESVAR LTPGRELGWPYCNPDGPPPAKLIRDLQTNPDGAEMDCAALPPIEQTLGAHSAPLGMSFAELPQPFGQGAL VGVHGSWNRDAPRAPEVSFFAWRDGTLGPQQTLVGGFQDDDGQRWGRPVAAVTGPDGAVYITDDFAGAVY RLAPPP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0214 | - | - | 100% (427) | L-sorbosone dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_1214 | - | 3e-07 | 22.83% (381) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_5629 | - | 1e-06 | 27.00% (237) | hypothetical protein MSMEG_5629 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0697 | - | 1e-167 | 67.36% (435) | SMP-30/gluconolaconase/LRE-like region |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_5210 | - | 1e-05 | 28.14% (167) | hypothetical protein MAV_5210 |
| M. thermoresistible (build 8) | TH_2267 | - | 6e-08 | 24.06% (374) | oxidoreductase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0146 | - | 1e-166 | 68.84% (430) | SMP-30/gluconolaconase/LRE-like region |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0697|M.gilvum_PYR-GCK --------MRESVRHNRIGVLVLGCALLAGCSGEQSSPSSTPTPT-----
Mvan_0146|M.vanbaalenii_PYR-1 --------MRDLVRHKPIGAILLGVALLAGCTAER---QAEPSPT-----
MSMEG_0214|M.smegmatis_MC2_155 --------MRAWPGIS--AVVVTASVVLAGCGTEPQTTEPTAQPS-----
TH_2267|M.thermoresistible__bu -----VAVGRIRRTTVRAAVALMCLALLAAACDGEAVPAPPAPPE-----
MAV_5210|M.avium_104 MPAIDVAPGWRLDRVTAPSRLFGANGLRTGPDGRIYIAQVTGSQISALDH
. . : :.
Mflv_0697|M.gilvum_PYR-GCK -AAPSSSSTSTTQPVAGTQTVTVEVAPDLGDSPFDEPRQ-AVVPKGWTLS
Mvan_0146|M.vanbaalenii_PYR-1 -APPP-ASTTPAAPAAGTARVTVEVDADLAGAPFDAPRE-AMVPQGWTLS
MSMEG_0214|M.smegmatis_MC2_155 -RSSSQTTAEHPAGAAELTPVTVEVPEGLDDAPLDQPRQ-ALVPDGWTLE
TH_2267|M.thermoresistible__bu -QPPAQTGESGARDVVTDLGVPWGIAFLPDGSALIAERDSGMIKQLSEPG
MAV_5210|M.avium_104 HTGELETASPKGGDIVAPDDVAFDAAGNLYATEVMDGRVSVRDTGGRTRV
: . *. : . *
Mflv_0697|M.gilvum_PYR-GCK VWARTSRPRLMAWAPDGALLVSVPSTGQVLSFRPRGDGPPEESVLLDDLD
Mvan_0146|M.vanbaalenii_PYR-1 VWARTPRPRLAAWTPDGDLLVSVPSAGRVLRFEPRGDGPPDESVLLDGLD
MSMEG_0214|M.smegmatis_MC2_155 VVARVPKARMAAWAPDGALLVSVPSTGEVLKVLP------TQSTLLDGLD
TH_2267|M.thermoresistible__bu VVRDVGAVEGVAARGEGGLLGLATAGDTVFAYHT----------------
MAV_5210|M.avium_104 LRDDVPSANGITFHRGRLFIGECRERGRLLEFDLAGG---PPRVLLDNVP
: . . : :: . ::
Mflv_0697|M.gilvum_PYR-GCK EPHGLAFDGPTLYVAQSDQVDGYDYAGGAATNPRVVAGGLPDDRSPDLRG
Mvan_0146|M.vanbaalenii_PYR-1 EPHGLAFDGSTLYVAESDQVDAYRYAAGAATEPRTVAGGLPDDRSPDLRG
MSMEG_0214|M.smegmatis_MC2_155 QPHGLFFAGPTLYVAESDQIDAYDYADGAAVNRRTVIDGLPDAKSPDLRG
TH_2267|M.thermoresistible__bu -------------TATDNRVVRMDFDGQALGPPAPILTGIP-------TG
MAV_5210|M.avium_104 SPNAMEVGPDGLLYFPVMGANEIWRVDPDGGEPQCVATGLGVPDSVKFDA
: *: .
Mflv_0697|M.gilvum_PYR-GCK AYSHVLKSVAVGPDGAVYFSIG-----STGNISADDRDATPPRATIMRVP
Mvan_0146|M.vanbaalenii_PYR-1 AYAHALKSVAVGPDGAVYFSIG-----STGNISAQDRSADPPRATVMRVP
MSMEG_0214|M.smegmatis_MC2_155 AYAHALKSVVVGDDGAVYFSIG-----STGNISAEDRTADPPRATIMRVP
TH_2267|M.thermoresistible__bu GSRHDGGRIAFGPDGRLYVATG-----EIGDPPLAQDRSSLAGKILRINP
MAV_5210|M.avium_104 RGHIVSTQVASGQVLRIDPRSGEQQVLAQLNPGLDNCTFVGDRLFVSNFT
:. * : * : : : .
Mflv_0697|M.gilvum_PYR-GCK PGGGPAEP-------FATGVRNGTGLAVAPDGAVWIANNGRDNIAFPDPE
Mvan_0146|M.vanbaalenii_PYR-1 PGGGRAEP-------FATGVRNGTGLAVAPDGAVWTANNGRDNVAYPEPG
MSMEG_0214|M.smegmatis_MC2_155 PGGGPAEP-------FATGVRNGTGLAFAPDGSLWTAVNNRDNVADPD--
TH_2267|M.thermoresistible__bu DGSIPADNPDPQSPVWSFGHRNVQGLAWDPGGRLWATEYG----------
MAV_5210|M.avium_104 GEITEISPDGTTRSVLPGGLNWPLDLAVGHDGRLYVADGTYFYAALPDGA
. . * . .** .* :: :
Mflv_0697|M.gilvum_PYR-GCK PSYGEVLPDY--------VDDNPPEQIARLTPGRELG--WPYCNN-----
Mvan_0146|M.vanbaalenii_PYR-1 PSYGQVIPEY--------VNDNPPEQIARLTPGRELG--WPYCNN-----
MSMEG_0214|M.smegmatis_MC2_155 ---GRVVQSY--------VDDHPPESVARLTPGRELG--WPYCN------
TH_2267|M.thermoresistible__bu --------------------ADTWDELNLIEPGGNYG--WPVAE------
MAV_5210|M.avium_104 LHTVGMLFSPGYPGFLRGVAASGPGEFVVTTSGGQISRYRPQASESEVLA
.. .* : . * ..
Mflv_0697|M.gilvum_PYR-GCK -----VGAPADLPFVRDVQTNPDGELLDCAALPPVEQSMGAHSAPLGLSF
Mvan_0146|M.vanbaalenii_PYR-1 -----VDGPADLPFVRDVQTNPDGALLDCAALPPVEQSMGAHSAPLGLSF
MSMEG_0214|M.smegmatis_MC2_155 -----PDGPPPAKLIRDLQTNPDGAEMDCAALPPIEQTLGAHSAPLGMSF
TH_2267|M.thermoresistible__bu -----------------------GRQEMPGMIDPVLQWRPAEASPSGLAF
MAV_5210|M.avium_104 DGFDQLYGIAPGPAGVVVAELGTGRVLSLQRSGAVEVLAAGLREPVGVAI
* .: . * *:::
Mflv_0697|M.gilvum_PYR-GCK TDG--VLPEPYASGALVGVHGS----WNRQPPRAPEVSFYPWRDGGLGDQ
Mvan_0146|M.vanbaalenii_PYR-1 VDG--ELPAPFQRGALVGVHGS----WNRQPPRAPEVSFYPWQDGTLGGQ
MSMEG_0214|M.smegmatis_MC2_155 AE----LPQPFGQGALVGVHGS----WNRDAPRAPEVSFFAWRDGTLGPQ
TH_2267|M.thermoresistible__bu WDG---------ALWIANLRGQ----RLLEVPVRADGELGEPVSRFVGEY
MAV_5210|M.avium_104 GSDGAALVAEAGAGRVVRVDGSKVDTVMADLQRPQGILLHGGVLYVVDAG
. :. : *. : : :.
Mflv_0697|M.gilvum_PYR-GCK QTLVGGFQADDGSRWGRPVAATTGP-------------------------
Mvan_0146|M.vanbaalenii_PYR-1 QTLVGGFQTDDGTRWGRPVAAVVGP-------------------------
MSMEG_0214|M.smegmatis_MC2_155 QTLVGGFQDDDGQRWGRPVAAVTGP-------------------------
TH_2267|M.thermoresistible__bu GRLRTVVAAPDGSLW-----FTTSN-------------------------
MAV_5210|M.avium_104 AKELIAFDPADKTRRTIASGLPVGPPPGVNPKPLKGMPPFSGPQGPFAGI
. * ..
Mflv_0697|M.gilvum_PYR-GCK ----DGSVYITDDAADAIYRLTPPA---
Mvan_0146|M.vanbaalenii_PYR-1 ----DGAVYITDDAADAIYRLAPG----
MSMEG_0214|M.smegmatis_MC2_155 ----DGAVYITDDFAGAVYRLAPPP---
TH_2267|M.thermoresistible__bu ----RDGRGVPRSGDDRILRYRR-----
MAV_5210|M.avium_104 TAAADGTLYVSADGEGSVLALRPTRDGH
. :. . . :