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RVLDLVVIVVYLVAIAWFGLRASGRQKTSKDYFVGEGKLPWWTVSFSVVATETSVLTVISVPGGAYSGQA FGNVELALGYVVGRVVVAVVLIPLYKRGGFVSAYQYLGTRFGLKLQGLASVTFVFTRLLAEGVRLFASAI PIKLLLDEFGVHADYRTIIVVVTAITVVYTYLGGIKAVVWTDAVQMTLYLGGAILAIIVLWGHVGSTGVA DALHAGKFDVFDTNFSLAHIATSTFALPTAIIGGAIFAMASHGSDQLIVQRILATRTLRDSQKAMIASGV FITFQFAAFSLVGALLWSYNGGRTFQELGLASSDNLYPNFILHGLPVVVSGLLVASILGAAMGSLSAALN SMSSSSVSDFINSFLSRSPSEQSLLRLGRLMTLVWAVLMAVFACGFSANTGNVYLTGLAIAGYTYGALLG AFLLGRLVRRANQFDAVVSFVVTVVVMTYIVRYVKIDVTASGETVPSAIAAQWLVPIGVLITLLVGGVMS RFHRPPEVAALPDHDDESATVPTVAGRN*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_0190 | - | - | 100% (519) | integral membrane transport protein |
M. smegmatis MC2 155 | MSMEG_3689 | - | 1e-22 | 22.36% (559) | sodium:solute symporter |
M. smegmatis MC2 155 | MSMEG_4462 | - | 4e-16 | 24.62% (459) | sodium:solute symporter |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | - | - | - | - | - |
M. gilvum PYR-GCK | Mflv_2139 | - | 2e-12 | 21.47% (531) | SSS family solute/sodium (Na+) symporter |
M. tuberculosis H37Rv | - | - | - | - | - |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_4639 | - | 1e-23 | 22.73% (440) | putative Na+/solute symporter |
M. marinum M | - | - | - | - | - |
M. avium 104 | - | - | - | - | - |
M. thermoresistible (build 8) | TH_3825 | - | 2e-09 | 22.96% (466) | PUTATIVE putative Na+/solute symporter |
M. ulcerans Agy99 | - | - | - | - | - |
M. vanbaalenii PYR-1 | Mvan_4564 | - | 9e-12 | 21.28% (531) | SSS family solute/sodium (Na+) symporter |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_2139|M.gilvum_PYR-GCK MTTLLAQSETVGNPLANIGIFSLFVVVTMIVVIRASKRNATADEFFTGGR Mvan_4564|M.vanbaalenii_PYR-1 MTTLLAQTETIGNPVANIGIFSLFVVVTMIVVIRASKRNATADEFFTGGR TH_3825|M.thermoresistible__bu --------------MILTGVAVFLLVLTVSGVVSARRVRGDCANYLVAGR MAB_4639|M.abscessus_ATCC_1997 ----MTGSLRLDAGPVDYVLIAIYFVFVLGIGLLARRGVSSSIDFFLSGR MSMEG_0190|M.smegmatis_MC2_155 ------------MRVLDLVVIVVYLVAIAWFGLRASGRQKTSKDYFVGEG : . .* : * . ::: . Mflv_2139|M.gilvum_PYR-GCK GFSGPQNGIAIAGDYLSAASFLGIAGAIAVYG-YDGFLYSIGFLVAWLVA Mvan_4564|M.vanbaalenii_PYR-1 GFSGPQNGIAIAGDYLSAASFLGIAGAIAVYG-YDGFLYSIGFLVAWLVA TH_3825|M.thermoresistible__bu ALPAVLVAAVLIAQPVDSNATIGNADLSAAFGFWAGAALPIGLALCLLLM MAB_4639|M.abscessus_ATCC_1997 SLPAWVTGLAFVSANLGAVEIMGMSANGAQFGMVGMHYFWIGAVPAILFL MSMEG_0190|M.smegmatis_MC2_155 KLPWWTVSFSVVATETSVLTVISVPGGAYSGQAFGNVELALGYVVGRVVV :. . . . . :. . :* :. Mflv_2139|M.gilvum_PYR-GCK LLLVAELLRNTGRFTMADVLSFRLKQRPVRLAAATNTLTVSLFYLLAQMA Mvan_4564|M.vanbaalenii_PYR-1 LLLVAELLRNTGRFTMADVLSFRLKQRPVRLAAATNTLTVSLFYLLAQMA TH_3825|M.thermoresistible__bu GLFFARRLRAAQVVTLPEYFGNRFG-RGVEVASSALTVGSFAILLAGNLV MAB_4639|M.abscessus_ATCC_1997 GIVMMPFFYGSQVRSVPEYMLHRFG-VGAHLVNATGFAVAQVLIAGVNLY MSMEG_0190|M.smegmatis_MC2_155 AVVLIPLYKRGGFVSAYQYLGTRFG-LKLQGLASVTFVFTRLLAEGVRLF :.. : : : *: . :. : .: Mflv_2139|M.gilvum_PYR-GCK GAGGLVALLLDIN-SRAGQSVVIAVVGVLMIVYVLVGGMKGTTWVQIIKA Mvan_4564|M.vanbaalenii_PYR-1 GAGGLVALLLDIN-SRTGQSVVIAVVGVLMIVYVLVGGMKGTTWVQIIKA TH_3825|M.thermoresistible__bu AIGFLLERFLGVS-YTIG----ILVTVPLALLYTITGGMFASVYTGVAQV MAB_4639|M.abscessus_ATCC_1997 LLGTIVNVLLGWP-LWVS----VIAAAAIVLCYITLGGLSAAIYNEVLQF MSMEG_0190|M.smegmatis_MC2_155 ASAIPIKLLLDEFGVHADYRTIIVVVTAITVVYTYLGGIKAVVWTDAVQM . : :*. . : .. : : * **: . : : Mflv_2139|M.gilvum_PYR-GCK VLLIAGAGFMTVMVLAKFG--LNFSEILGS-AQSAISG-ATTAGVADRDV Mvan_4564|M.vanbaalenii_PYR-1 VLLIAGAGFMTVMVLAKFG--MNFSEILGS-AQSAISG-STTTGVAGRDV TH_3825|M.thermoresistible__bu VVNIVGVFALVVWVAATHG--FTAPDGMGAGALSQLTS-SESGAVIN--- MAB_4639|M.abscessus_ATCC_1997 FVIVAALLPLTIVGLHQVGGWQGLQDKVSAGQMSSWPG-NELSGFSDNLL MSMEG_0190|M.smegmatis_MC2_155 TLYLGGAILAIIVLWGHVG-STGVADALHAGKFDVFDTNFSLAHIATSTF : : . : * : : : . . Mflv_2139|M.gilvum_PYR-GCK LAPGAQYGGSLTSQINFISLALALVLGTAGLPHVLMRFYTVPTAKEARRS Mvan_4564|M.vanbaalenii_PYR-1 LAPGAQYGGSLTSQINFISLAIALVLGTAGLPHVLMRFYTVPTAKEARRS TH_3825|M.thermoresistible__bu -----------------WATIIALGLGNLVAIDLMQRVFSARDPGAAQR- MAB_4639|M.abscessus_ATCC_1997 SVIGIVFG---------LGFVLSFGYWTTNFVEVQRALASESLSAARRTP MSMEG_0190|M.smegmatis_MC2_155 ALPTAIIG----------GAIFAMASHGSDQLIVQRILATRTLRDSQKAM . ::: : . : : Mflv_2139|M.gilvum_PYR-GCK VVWAIALIGAFYLFTLVLGYGAAALVGPDRILGAAGGVNS------AAPL Mvan_4564|M.vanbaalenii_PYR-1 VVWAIALIGAFYLFTLVLGYGAAALVGPDRILGAAGGVNS------AAPL TH_3825|M.thermoresistible__bu --ACFAAAGGILLLCLPLSFVALAAVG---IVGDSAGDGP------ILYA MAB_4639|M.abscessus_ATCC_1997 IIGAFPKMFIPFIVVIPGMICAVLVPQMVAYKAGQPTSDPNLTYSNSLLY MSMEG_0190|M.smegmatis_MC2_155 IASGVFITFQFAAFSLVGALLWSYNGGRTFQELGLASSDN------LYPN . . : . Mflv_2139|M.gilvum_PYR-GCK LAFELGGVILLGVISAVAFATILAVVAGLTITASASFAHDIY---ASVLK Mvan_4564|M.vanbaalenii_PYR-1 LAFELGGVVLLGVISAVAFATILAVVAGLTITASASFAHDIY---ASVMK TH_3825|M.thermoresistible__bu LLGEYAPAWLAIIVISGLLAATLTTVSGILLSTASVLVRNVLRIDTGVLA MAB_4639|M.abscessus_ATCC_1997 LMKEVLPNGVLGVAITGLLASFMAGMAANVSAFNTVFSYDLW----QRYI MSMEG_0190|M.smegmatis_MC2_155 FILHGLPVVVSGLLVASILGAAMGSLSAALNSMSSSSVSDFIN----SFL : . : : : :.: : ::. : : :. Mflv_2139|M.gilvum_PYR-GCK SHKVTEAEQVKVSRITAVVLGILAIGLGILANGQ-NIAFLVALAFA-VAA Mvan_4564|M.vanbaalenii_PYR-1 SHKVTEAEQVRVSRITAVVLGVLAIGLGILANGQ-NIAFLVALAFA-VAA TH_3825|M.thermoresistible__bu PPAAMTPRMLRATRWATLPMAALAAVVALRVP---QTGILLTLAFD-LLL MAB_4639|M.abscessus_ATCC_1997 RKDRPDGYYLRIGRIATVGATVIAIGTAFIAANYNNVMNYLQTLFA-FFN MSMEG_0190|M.smegmatis_MC2_155 SRSPSEQSLLRLGRLMTLVWAVLMAVFACGFSANTGNVYLTGLAIAGYTY :: * :: : . : Mflv_2139|M.gilvum_PYR-GCK AANLPTIIYSLYWKRFNTRGALWSMYGGLISTIVLIVFSPA--------- Mvan_4564|M.vanbaalenii_PYR-1 AANLPTIIYSLYWRRFNTRGALWSMYGGLISTIVLIVFSPA--------- TH_3825|M.thermoresistible__bu ASLVVPFILGLYWSRGGAAAAAAAVVVGIGVRLTYFVLAPT--------- MAB_4639|M.abscessus_ATCC_1997 APLFATFILGMFWRRMTATAGWAGLVSGTFAAVGIWSLFETGVYTLAGQG MSMEG_0190|M.smegmatis_MC2_155 GALLGAFLLGRLVRRANQFDAVVSFVVTVVVMTYIVRYVKID-------- .. . .:: . * . .. Mflv_2139|M.gilvum_PYR-GCK ----VSGSKTAMIPGADFAFFPLANPGIVSIPLAFILGIVGTLTSPDDED Mvan_4564|M.vanbaalenii_PYR-1 ----VSGSKTAMIPGADFAWFPLANPGIVSIPLAFILGIVGTLTSPDDED TH_3825|M.thermoresistible__bu ----IYG--------VDNTLLYLPNDWVSAX------XRGGGPSGVRDTP MAB_4639|M.abscessus_ATCC_1997 SNFIEAGVAFTVDIVVSVAVSWTTEPKPAAELAGLVYSETPHAFSSDEPA MSMEG_0190|M.smegmatis_MC2_155 -----------VTASGETVPSAIAAQWLVPIGVLITLLVGGVMSRFHRPP . . . . Mflv_2139|M.gilvum_PYR-GCK P---KVAAEMEVRSLTGIGAEKAVSH Mvan_4564|M.vanbaalenii_PYR-1 P---KVAAEMEVRSLTGIGAEKAVAH TH_3825|M.thermoresistible__bu S---DTPREMHPRNALA--------- MAB_4639|M.abscessus_ATCC_1997 SGWFRQPVKLAMTALILVVALNLIFH MSMEG_0190|M.smegmatis_MC2_155 EVAALPDHDDESATVPTVAGRN---- .