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M. smegmatis MC2 155 MSMEG_0190 (-)

annotation: integral membrane transport protein
coordinates: 214183 - 215742
length: 519

RVLDLVVIVVYLVAIAWFGLRASGRQKTSKDYFVGEGKLPWWTVSFSVVATETSVLTVISVPGGAYSGQA
FGNVELALGYVVGRVVVAVVLIPLYKRGGFVSAYQYLGTRFGLKLQGLASVTFVFTRLLAEGVRLFASAI
PIKLLLDEFGVHADYRTIIVVVTAITVVYTYLGGIKAVVWTDAVQMTLYLGGAILAIIVLWGHVGSTGVA
DALHAGKFDVFDTNFSLAHIATSTFALPTAIIGGAIFAMASHGSDQLIVQRILATRTLRDSQKAMIASGV
FITFQFAAFSLVGALLWSYNGGRTFQELGLASSDNLYPNFILHGLPVVVSGLLVASILGAAMGSLSAALN
SMSSSSVSDFINSFLSRSPSEQSLLRLGRLMTLVWAVLMAVFACGFSANTGNVYLTGLAIAGYTYGALLG
AFLLGRLVRRANQFDAVVSFVVTVVVMTYIVRYVKIDVTASGETVPSAIAAQWLVPIGVLITLLVGGVMS
RFHRPPEVAALPDHDDESATVPTVAGRN*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0190--100% (519)integral membrane transport protein
M. smegmatis MC2 155MSMEG_3689-1e-2222.36% (559) sodium:solute symporter
M. smegmatis MC2 155MSMEG_4462-4e-1624.62% (459) sodium:solute symporter

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_2139-2e-1221.47% (531) SSS family solute/sodium (Na+) symporter
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4639-1e-2322.73% (440) putative Na+/solute symporter
M. marinum M-----
M. avium 104-----
M. thermoresistible (build 8)TH_3825-2e-0922.96% (466) PUTATIVE putative Na+/solute symporter
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_4564-9e-1221.28% (531) SSS family solute/sodium (Na+) symporter

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2139|M.gilvum_PYR-GCK          MTTLLAQSETVGNPLANIGIFSLFVVVTMIVVIRASKRNATADEFFTGGR
Mvan_4564|M.vanbaalenii_PYR-1       MTTLLAQTETIGNPVANIGIFSLFVVVTMIVVIRASKRNATADEFFTGGR
TH_3825|M.thermoresistible__bu      --------------MILTGVAVFLLVLTVSGVVSARRVRGDCANYLVAGR
MAB_4639|M.abscessus_ATCC_1997      ----MTGSLRLDAGPVDYVLIAIYFVFVLGIGLLARRGVSSSIDFFLSGR
MSMEG_0190|M.smegmatis_MC2_155      ------------MRVLDLVVIVVYLVAIAWFGLRASGRQKTSKDYFVGEG
                                                       :  . .*      : *      . ::: .  

Mflv_2139|M.gilvum_PYR-GCK          GFSGPQNGIAIAGDYLSAASFLGIAGAIAVYG-YDGFLYSIGFLVAWLVA
Mvan_4564|M.vanbaalenii_PYR-1       GFSGPQNGIAIAGDYLSAASFLGIAGAIAVYG-YDGFLYSIGFLVAWLVA
TH_3825|M.thermoresistible__bu      ALPAVLVAAVLIAQPVDSNATIGNADLSAAFGFWAGAALPIGLALCLLLM
MAB_4639|M.abscessus_ATCC_1997      SLPAWVTGLAFVSANLGAVEIMGMSANGAQFGMVGMHYFWIGAVPAILFL
MSMEG_0190|M.smegmatis_MC2_155      KLPWWTVSFSVVATETSVLTVISVPGGAYSGQAFGNVELALGYVVGRVVV
                                     :.    .  . .   .    :. .               :*     :. 

Mflv_2139|M.gilvum_PYR-GCK          LLLVAELLRNTGRFTMADVLSFRLKQRPVRLAAATNTLTVSLFYLLAQMA
Mvan_4564|M.vanbaalenii_PYR-1       LLLVAELLRNTGRFTMADVLSFRLKQRPVRLAAATNTLTVSLFYLLAQMA
TH_3825|M.thermoresistible__bu      GLFFARRLRAAQVVTLPEYFGNRFG-RGVEVASSALTVGSFAILLAGNLV
MAB_4639|M.abscessus_ATCC_1997      GIVMMPFFYGSQVRSVPEYMLHRFG-VGAHLVNATGFAVAQVLIAGVNLY
MSMEG_0190|M.smegmatis_MC2_155      AVVLIPLYKRGGFVSAYQYLGTRFG-LKLQGLASVTFVFTRLLAEGVRLF
                                     :..          :  : :  *:     .   :.       :    .: 

Mflv_2139|M.gilvum_PYR-GCK          GAGGLVALLLDIN-SRAGQSVVIAVVGVLMIVYVLVGGMKGTTWVQIIKA
Mvan_4564|M.vanbaalenii_PYR-1       GAGGLVALLLDIN-SRTGQSVVIAVVGVLMIVYVLVGGMKGTTWVQIIKA
TH_3825|M.thermoresistible__bu      AIGFLLERFLGVS-YTIG----ILVTVPLALLYTITGGMFASVYTGVAQV
MAB_4639|M.abscessus_ATCC_1997      LLGTIVNVLLGWP-LWVS----VIAAAAIVLCYITLGGLSAAIYNEVLQF
MSMEG_0190|M.smegmatis_MC2_155      ASAIPIKLLLDEFGVHADYRTIIVVVTAITVVYTYLGGIKAVVWTDAVQM
                                      .  :  :*.      .    : ..  : : *   **: .  :    : 

Mflv_2139|M.gilvum_PYR-GCK          VLLIAGAGFMTVMVLAKFG--LNFSEILGS-AQSAISG-ATTAGVADRDV
Mvan_4564|M.vanbaalenii_PYR-1       VLLIAGAGFMTVMVLAKFG--MNFSEILGS-AQSAISG-STTTGVAGRDV
TH_3825|M.thermoresistible__bu      VVNIVGVFALVVWVAATHG--FTAPDGMGAGALSQLTS-SESGAVIN---
MAB_4639|M.abscessus_ATCC_1997      FVIVAALLPLTIVGLHQVGGWQGLQDKVSAGQMSSWPG-NELSGFSDNLL
MSMEG_0190|M.smegmatis_MC2_155      TLYLGGAILAIIVLWGHVG-STGVADALHAGKFDVFDTNFSLAHIATSTF
                                     : : .     :      *      : : :   .          .     

Mflv_2139|M.gilvum_PYR-GCK          LAPGAQYGGSLTSQINFISLALALVLGTAGLPHVLMRFYTVPTAKEARRS
Mvan_4564|M.vanbaalenii_PYR-1       LAPGAQYGGSLTSQINFISLAIALVLGTAGLPHVLMRFYTVPTAKEARRS
TH_3825|M.thermoresistible__bu      -----------------WATIIALGLGNLVAIDLMQRVFSARDPGAAQR-
MAB_4639|M.abscessus_ATCC_1997      SVIGIVFG---------LGFVLSFGYWTTNFVEVQRALASESLSAARRTP
MSMEG_0190|M.smegmatis_MC2_155      ALPTAIIG----------GAIFAMASHGSDQLIVQRILATRTLRDSQKAM
                                                      .  :::         :   . :       :  

Mflv_2139|M.gilvum_PYR-GCK          VVWAIALIGAFYLFTLVLGYGAAALVGPDRILGAAGGVNS------AAPL
Mvan_4564|M.vanbaalenii_PYR-1       VVWAIALIGAFYLFTLVLGYGAAALVGPDRILGAAGGVNS------AAPL
TH_3825|M.thermoresistible__bu      --ACFAAAGGILLLCLPLSFVALAAVG---IVGDSAGDGP------ILYA
MAB_4639|M.abscessus_ATCC_1997      IIGAFPKMFIPFIVVIPGMICAVLVPQMVAYKAGQPTSDPNLTYSNSLLY
MSMEG_0190|M.smegmatis_MC2_155      IASGVFITFQFAAFSLVGALLWSYNGGRTFQELGLASSDN------LYPN
                                        .        . :                      .           

Mflv_2139|M.gilvum_PYR-GCK          LAFELGGVILLGVISAVAFATILAVVAGLTITASASFAHDIY---ASVLK
Mvan_4564|M.vanbaalenii_PYR-1       LAFELGGVVLLGVISAVAFATILAVVAGLTITASASFAHDIY---ASVMK
TH_3825|M.thermoresistible__bu      LLGEYAPAWLAIIVISGLLAATLTTVSGILLSTASVLVRNVLRIDTGVLA
MAB_4639|M.abscessus_ATCC_1997      LMKEVLPNGVLGVAITGLLASFMAGMAANVSAFNTVFSYDLW----QRYI
MSMEG_0190|M.smegmatis_MC2_155      FILHGLPVVVSGLLVASILGAAMGSLSAALNSMSSSSVSDFIN----SFL
                                    :  .     :  :  :  :.: :  ::.   :  :    :.         

Mflv_2139|M.gilvum_PYR-GCK          SHKVTEAEQVKVSRITAVVLGILAIGLGILANGQ-NIAFLVALAFA-VAA
Mvan_4564|M.vanbaalenii_PYR-1       SHKVTEAEQVRVSRITAVVLGVLAIGLGILANGQ-NIAFLVALAFA-VAA
TH_3825|M.thermoresistible__bu      PPAAMTPRMLRATRWATLPMAALAAVVALRVP---QTGILLTLAFD-LLL
MAB_4639|M.abscessus_ATCC_1997      RKDRPDGYYLRIGRIATVGATVIAIGTAFIAANYNNVMNYLQTLFA-FFN
MSMEG_0190|M.smegmatis_MC2_155      SRSPSEQSLLRLGRLMTLVWAVLMAVFACGFSANTGNVYLTGLAIAGYTY
                                             ::  *  ::    :    .                :     

Mflv_2139|M.gilvum_PYR-GCK          AANLPTIIYSLYWKRFNTRGALWSMYGGLISTIVLIVFSPA---------
Mvan_4564|M.vanbaalenii_PYR-1       AANLPTIIYSLYWRRFNTRGALWSMYGGLISTIVLIVFSPA---------
TH_3825|M.thermoresistible__bu      ASLVVPFILGLYWSRGGAAAAAAAVVVGIGVRLTYFVLAPT---------
MAB_4639|M.abscessus_ATCC_1997      APLFATFILGMFWRRMTATAGWAGLVSGTFAAVGIWSLFETGVYTLAGQG
MSMEG_0190|M.smegmatis_MC2_155      GALLGAFLLGRLVRRANQFDAVVSFVVTVVVMTYIVRYVKID--------
                                    .. . .:: .    *     .  ..                         

Mflv_2139|M.gilvum_PYR-GCK          ----VSGSKTAMIPGADFAFFPLANPGIVSIPLAFILGIVGTLTSPDDED
Mvan_4564|M.vanbaalenii_PYR-1       ----VSGSKTAMIPGADFAWFPLANPGIVSIPLAFILGIVGTLTSPDDED
TH_3825|M.thermoresistible__bu      ----IYG--------VDNTLLYLPNDWVSAX------XRGGGPSGVRDTP
MAB_4639|M.abscessus_ATCC_1997      SNFIEAGVAFTVDIVVSVAVSWTTEPKPAAELAGLVYSETPHAFSSDEPA
MSMEG_0190|M.smegmatis_MC2_155      -----------VTASGETVPSAIAAQWLVPIGVLITLLVGGVMSRFHRPP
                                                    . .    .     .                    

Mflv_2139|M.gilvum_PYR-GCK          P---KVAAEMEVRSLTGIGAEKAVSH
Mvan_4564|M.vanbaalenii_PYR-1       P---KVAAEMEVRSLTGIGAEKAVAH
TH_3825|M.thermoresistible__bu      S---DTPREMHPRNALA---------
MAB_4639|M.abscessus_ATCC_1997      SGWFRQPVKLAMTALILVVALNLIFH
MSMEG_0190|M.smegmatis_MC2_155      EVAALPDHDDESATVPTVAGRN----
                                            .