For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_0188 (-)

annotation: MarR-family protein transcriptional regulator
coordinates: 212103 - 212558
length: 151

VVDTRSVEAISEMIITGTDLLWRHLVDRTALSSSATLLLNRLERQGPMRLTALAEAEGASQSGMTQLVQR
LEQQGLVERCSDPEDGRARLVAISEAGRKQWDTRAEIRRQRLTGLLAAVPADDQVALALAAQIGARVLTQ
MREIADAGLSE
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0188--100% (151)MarR-family protein transcriptional regulator
M. smegmatis MC2 155MSMEG_4471-2e-1236.97% (119) MarR-family protein transcriptional regulator
M. smegmatis MC2 155MSMEG_5668-1e-0828.91% (128) putative transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2354-2e-0935.19% (108) hypothetical protein Mb2354
M. gilvum PYR-GCKMflv_0856-1e-1040.19% (107) MarR family transcriptional regulator
M. tuberculosis H37RvRv2327-2e-0935.19% (108) hypothetical protein Rv2327
M. leprae Br4923MLBr_02696-8e-0938.78% (98) putative MarR-family regulatory protein
M. abscessus ATCC 19977MAB_0157-4e-0936.56% (93) putative transcriptional regulator MarR
M. marinum MMMAR_3627-5e-0934.26% (108) hypothetical protein MMAR_3627
M. avium 104MAV_4734-1e-0936.59% (82) MarR-family protein regulatory protein
M. thermoresistible (build 8)TH_0729-4e-1030.41% (148) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_1238-4e-0934.26% (108) hypothetical protein MUL_1238
M. vanbaalenii PYR-1Mvan_6049-8e-1035.82% (134) MarR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0856|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_6049|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_02696|M.leprae_Br4923          MFSYITTKSWNPGNQSRYSRPRRLSAYNGLYPKYFDVLDFTNDDPLHPAP
Mb2354|M.bovis_AF2122/97            --------------------------------------------------
Rv2327|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_3627|M.marinum_M               --------------------------------------------------
MUL_1238|M.ulcerans_Agy99           --------------------------------------------------
TH_0729|M.thermoresistible__bu      --------------------------------------------------
MAB_0157|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_4734|M.avium_104                --------------------------------------------------
MSMEG_0188|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0856|M.gilvum_PYR-GCK          --------------------------MVT-----TDAQVSELAGELQRVL
Mvan_6049|M.vanbaalenii_PYR-1       --------------------------MVP-----TEARVSELASELQRVL
MLBr_02696|M.leprae_Br4923          PHLRPPLQLAHTRSLNARHIALNCRLMADS--EFTAHEVTELADGLHRAL
Mb2354|M.bovis_AF2122/97            --------------------------MSPSPAAANRSEVGGPLPGLGADL
Rv2327|M.tuberculosis_H37Rv         --------------------------MSPSPAAANRSEVGGPLPGLGADL
MMAR_3627|M.marinum_M               --------------------------MTSS-ATANQAQVA---HGLGADL
MUL_1238|M.ulcerans_Agy99           --------------------------MTSS-ATANQAQVA---HGLGADL
TH_0729|M.thermoresistible__bu      --------------------------MKPPAVDPS--------TSLGADL
MAB_0157|M.abscessus_ATCC_1997      --------------------------MSTT-------------DGLTADV
MAV_4734|M.avium_104                -----------------------------------MDGVSDSAVAAARDI
MSMEG_0188|M.smegmatis_MC2_155      --------------------------MVDT-------------RSVEAIS
                                                                                      

Mflv_0856|M.gilvum_PYR-GCK          SKLMSVMR-HTGRTPTSGDLTLAQLSILLTLIDQGPMRMTELAAHEKVRT
Mvan_6049|M.vanbaalenii_PYR-1       SKVLSVMR-HTGRTATSGDLTLAQLSILLTLFDQGPMRMTELAAHEKVRT
MLBr_02696|M.leprae_Br4923          SKLFSILRRRTPNGAVSGELTLAQLSILVTLLDQGPIRMTDLAAHERVRT
Mb2354|M.bovis_AF2122/97            LAVVARLN-RLATQRIQMPLPAAQARLLATIEAQGEARIGDLAAVDHCSQ
Rv2327|M.tuberculosis_H37Rv         LAVVARLN-RLATQRIQMPLPAAQARLLATIEAQGEARIGDLAAVDHCSQ
MMAR_3627|M.marinum_M               LAVVARLN-RLATQRIQMPLPSAQARLLATIEAQGEARIGDLAAVDHCSQ
MUL_1238|M.ulcerans_Agy99           LAVVARLN-RLATQRIQMPLPSAQARLLATIEAQGEARIGDLAAVDHCSQ
TH_0729|M.thermoresistible__bu      LWVVSRIN-RLATQRIRLPLPVAQARLLSTIQDRGSARISDLAVLDHCSQ
MAB_0157|M.abscessus_ATCC_1997      LTVIARLN-RWVSSYADLPVPTGQARLLALVGEMEDARISDLAQADHCSQ
MAV_4734|M.avium_104                RVVFSRLRRRLKDIAVDG-LTPSQTAVLTRLWKEGPSSASALAAAERVRP
MSMEG_0188|M.smegmatis_MC2_155      EMIITGTDLLWRHLVDRTALSSSATLLLNRLERQGPMRLTALAEAEGASQ
                                      :.:              :. .   :*  :          **  :    

Mflv_0856|M.gilvum_PYR-GCK          PTTTVAIRRLEKLGLVKRDRDPSDLRAVLVDITPEGLAQHQEALAIRQAH
Mvan_6049|M.vanbaalenii_PYR-1       PTTTVAIRRLEKLGLVKRDRDPSDLRAVLVDITPEGLAQHREALASRQAH
MLBr_02696|M.leprae_Br4923          PTTTVAIRRLEKIGLVKRSRDLSDLRAVLVDITPRGRTVHGESLANRRAA
Mb2354|M.bovis_AF2122/97            PTMTTQVRRLEDAGLVTRTADPGDARAVRIRITPEGIRTLTAVRADRAAA
Rv2327|M.tuberculosis_H37Rv         PTMTTQVRRLEDAGLVTRTADPGDARAVRIRITPEGIRTLTAVRADRAAA
MMAR_3627|M.marinum_M               PTMTTQVRRLEDAGMVTRTVDPGDARAVRIRITPEGMRTLSAVRTDRAAA
MUL_1238|M.ulcerans_Agy99           PTMTTQVRRLEDAGMVTRTVDPGDARAVRIRITPEGMRTLSAVRTDRAAA
TH_0729|M.thermoresistible__bu      PTMTTQVRRLEEAGLVSRTVDPDDGRAVRISITPEGVRTLAQVRADRAAA
MAB_0157|M.abscessus_ATCC_1997      PTMTVQLKRLQDVGYVERRVDPADKRAQRIKLTSKGREALVAMRAQRQGV
MAV_4734|M.avium_104                QSMATILAALGQRRLIERSPDPNDKRRQVVSLTAAGRKRAESDRRAREEW
MSMEG_0188|M.smegmatis_MC2_155      SGMTQLVQRLEQQGLVERCSDPEDGRARLVAISEAGRKQWDTRAEIRRQR
                                       :  :  * .   : *  *  * *   : ::  *          *   

Mflv_0856|M.gilvum_PYR-GCK          LASLLGK-LSCDELDALTKALAPLERIAE---------------------
Mvan_6049|M.vanbaalenii_PYR-1       LASLLSK-LSDEELDALTKALAPLERIAE---------------------
MLBr_02696|M.leprae_Br4923          LTTMLSQ-LPTSDLNILKNALAPLQRLASGEPVS------SPAGDSPACK
Mb2354|M.bovis_AF2122/97            IEPQLAL-LPPADRRVLADAVDVLRRLLDHAAT-------TPGRATRQ--
Rv2327|M.tuberculosis_H37Rv         IEPQLAL-LPPADRRVLADAVDVLRRLLDHAAT-------TPGRATRQ--
MMAR_3627|M.marinum_M               IEPQLAR-LEPSDRQVLADAVEVLRRLLDNAAA-------TPGRNTL---
MUL_1238|M.ulcerans_Agy99           IEPQLAR-LEPSDRQVLAGAVEVLRRLLDNAAA-------TPGRNTL---
TH_0729|M.thermoresistible__bu      IDPYIDR-LSDTDRAVLADAVRVMRQLLADAADPAVLPADPPSRPHESTE
MAB_0157|M.abscessus_ATCC_1997      LDPWLST-LPAEEQRTLAEAAAILERLTRRMAA-------QSG-------
MAV_4734|M.avium_104                LARAIQERYTEAERRVIVEALSLLERLTEQ--------------------
MSMEG_0188|M.smegmatis_MC2_155      LTGLLAA-VPADDQVALALAAQIGARVLTQMREIADAGLSE---------
                                    :   :       :   :  *     ::                       

Mflv_0856|M.gilvum_PYR-GCK          --
Mvan_6049|M.vanbaalenii_PYR-1       --
MLBr_02696|M.leprae_Br4923          QA
Mb2354|M.bovis_AF2122/97            --
Rv2327|M.tuberculosis_H37Rv         --
MMAR_3627|M.marinum_M               --
MUL_1238|M.ulcerans_Agy99           --
TH_0729|M.thermoresistible__bu      LR
MAB_0157|M.abscessus_ATCC_1997      --
MAV_4734|M.avium_104                --
MSMEG_0188|M.smegmatis_MC2_155      --