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NYLVTALYIAAFALFILGLSGLTGPKTAVRGNLIAAAGMGLAVVATLIKVRDTATVNWVLIVVGLVLGVV LGVPPAKKTKMTAMPQLVALFNGVGGGTVALIAWAEFIETDGFGHFTPDQSPTVALVVGSLFAAIIGSVS FWGSLVAYLKLQESIPKNVEKALVRSAKVFQTSNVVLLLGAIATAAYIGLHAGTGNPLWLIVVVLVLAGI MGLFVVFPIGGADMPVVISLLNALTGLSAAAAGLALNNTAMIVAGMIVGASGSILTNLMAVAMNRSIPAI VFGSFGAGGDTAAVAGGEQGTAKSTSAADAAIQMAYANQVIVVPGYGLAVAQAQHAVKDMAAILESKGVE VKYAIHPVAGRMPGHMNVLLAEADVAYDAMKEMDDVNGEFSRTDVTLVIGANDVTNPAARNDPSSPIHGM PILNVDESKSVIVLKRSMSSGYAGIENPLFFLNHTSMLFGDAKKSVGEVIEELKAL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0150 | - | - | 100% (477) | NAD(P) transhydrogenase beta subunit |
| M. smegmatis MC2 155 | MSMEG_0109 | pntB | e-103 | 42.80% (486) | NAD(P) transhydrogenase, beta subunit |
| M. smegmatis MC2 155 | MSMEG_4108 | pntB | 1e-99 | 41.88% (480) | NAD(P) transhydrogenase, beta subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0162 | pntB | 0.0 | 72.71% (480) | NAD(P) transhydrogenase subunit beta |
| M. gilvum PYR-GCK | Mflv_0727 | - | 1e-100 | 43.43% (472) | NAD(P) transhydrogenase, beta subunit |
| M. tuberculosis H37Rv | Rv0157 | pntB | 0.0 | 72.71% (480) | NAD(P) transhydrogenase subunit beta |
| M. leprae Br4923 | MLBr_02634 | pntB | 0.0 | 71.25% (480) | pyridine transhydrogenase subunit beta |
| M. abscessus ATCC 19977 | MAB_4577c | - | 0.0 | 84.52% (478) | NAD(P) transhydrogenase, beta subunit PntB |
| M. marinum M | MMAR_0379 | pntB | 0.0 | 73.75% (480) | NAD(P) transhydrogenase (subunit beta) PntB |
| M. avium 104 | MAV_5140 | - | 0.0 | 74.69% (482) | NAD(P) transhydrogenase beta subunit |
| M. thermoresistible (build 8) | TH_0162 | pntB | 0.0 | 73.33% (480) | PROBABLE NAD(P) TRANSHYDROGENASE (SUBUNIT BETA) PNTB |
| M. ulcerans Agy99 | MUL_4733 | pntB | 0.0 | 73.33% (480) | NAD(P) transhydrogenase (subunit beta) PntB |
| M. vanbaalenii PYR-1 | Mvan_0119 | - | 1e-100 | 43.51% (478) | NAD(P) transhydrogenase, beta subunit |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0150|M.smegmatis_MC2_155 -----MNYLVTALYIAAFALFILGLSGLTGPKTAVRGNLIAAAGMGLAVV
MAB_4577c|M.abscessus_ATCC_199 MSSESLNYIVDVLYIAAFALFIYGLSGLTGPKTAVRGNWIAAVGMGIAVL
MMAR_0379|M.marinum_M -----MNYLVIGLYILAFSLFIYGLMGLTGPKTAVRGNLIAAVGMAIAVA
MUL_4733|M.ulcerans_Agy99 -----MNYLVIGLYILAFSLFIYGLMGLTEPKTAVRGNLIAAVGMAIAVA
MAV_5140|M.avium_104 -----MNYLVIGLYIVSFALFIYGLMGLTGPKTAVRGNLIAAVGMAIAVA
MLBr_02634|M.leprae_Br4923 -----MNYFVIGLYILAFALFITGLMGLTGPRTAVSGNLIAAVGMTIAVA
Mb0162|M.bovis_AF2122/97 ---MNLHYLVEILYIISFSLFIYGLMGLTGPKTAVRGNLIAAAGMTIAVA
Rv0157|M.tuberculosis_H37Rv ---MNLHYLVEILYIISFSLFIYGLMGLTGPKTAVRGNLIAAAGMTIAVA
TH_0162|M.thermoresistible__bu -----MNYVVSILYIVSFAMFIYGLMGLTGPKTAVRGNWIAAAGMAVAII
Mflv_0727|M.gilvum_PYR-GCK --MFTLETAATAAYVVAALLFILALAGLSKHETSRAGNTFGITGMAVALI
Mvan_0119|M.vanbaalenii_PYR-1 --MFTLETAATAAYVVAALLFILALAGLSRHETSRAGNTFGIVGMVVALV
:. . *: : :** .* **: .*: ** :. .** :*:
MSMEG_0150|M.smegmatis_MC2_155 AT--LIKVRDTAT-VNWVLIVVGLVLGVVLGVPPAKKTKMTAMPQLVALF
MAB_4577c|M.abscessus_ATCC_199 AT--LIKVSESATTLDWILIGAGLGIGVVLGIPPALKTKMTAMPQLVALF
MMAR_0379|M.marinum_M AT--LVKIRHTDQ---WVLIIAGLVVGVALGVPPARLTKMTAMPQLVAFF
MUL_4733|M.ulcerans_Agy99 AT--LVKIRHTDQ---WVLIIVGLVVGVALGVPPARLTKMTAMPQLVAFF
MAV_5140|M.avium_104 AT--LIKIRHTDQ---WVLIIAGLVVGVVLGVPPARYTKMTAMPQLVAFF
MLBr_02634|M.leprae_Br4923 AT--LVKIRHTEQ---WVLIIAALVVGIVLGFPPARLTKVTAMPQLVAFF
Mb0162|M.bovis_AF2122/97 AT--LVMIRHTSQ---WPLIIAGLVVGVVLGVPPARLTKMTAMPQLVAFF
Rv0157|M.tuberculosis_H37Rv AT--LVMIRHTSQ---WPLIIAGLVVGVVLGVPPARLTKMTAMPQLVAFF
TH_0162|M.thermoresistible__bu AT--LILIRDTDN---WPLIIAGLLIGVVLGVPPARMTKMTAMPQLVALF
Mflv_0727|M.gilvum_PYR-GCK ATVALAIARDIEP-LGLALLFAAMAIGAAIGLWRAKIVEMTGMPELIALL
Mvan_0119|M.vanbaalenii_PYR-1 ATIALALARHIEP-LGLALLVGAMTIGAAIGLWRAKIVEMTGMPELIALL
** * . *: .: :* .:*. * .::*.**:*:*::
MSMEG_0150|M.smegmatis_MC2_155 NGVGGGTVALIAWAEFIETDG----FGHFTPDQSPTVALVVGS-LFAAII
MAB_4577c|M.abscessus_ATCC_199 NGVGGGTVALIAWSEFIETKG----FSEFKPDQSPTVALVVGS-LFAAII
MMAR_0379|M.marinum_M NGVGGGTVALIALSEFIETKG----FSAFQHGESPTVHIVVAS-LFAAII
MUL_4733|M.ulcerans_Agy99 NGVGGGTVALIALSEFIETKG----FSAFQHGESPTVHIVVAS-LFAAII
MAV_5140|M.avium_104 NGVGGGTVALIALSEFIETSG----FSAFQHGESPTVHIVVAS-LFAAII
MLBr_02634|M.leprae_Br4923 NGVGGGTVALIALSEFIETSG----FSEFQHHESPTVHIVVAS-LFAAII
Mb0162|M.bovis_AF2122/97 NGVGGGTVALIALSEFIDTTG----FSAFQHGESPTVHIVVAS-LFAAII
Rv0157|M.tuberculosis_H37Rv NGVGGGTVALIALSEFIDTTG----FSAFQHGESPTVHIVVAS-LFAAII
TH_0162|M.thermoresistible__bu NGVGGGTVALIALAEFMDTEG----FSAFKHGEEPTVHIVVGS-LFAAII
Mflv_0727|M.gilvum_PYR-GCK HSFVGLAAVLVGWNGYLHVEGDPGGAEAAHLASEGMLGIHSGEVVIGVFI
Mvan_0119|M.vanbaalenii_PYR-1 HSFVGLAAVLVGWNGYLHVEGDPGSAEALQLGSEGMLGIHSAEVVIGVFI
:.. * :..*:. ::.. * .. : : .. ::..:*
MSMEG_0150|M.smegmatis_MC2_155 GSVSFWGSLVAYLKLQESIPKNVEKALVRSAKVFQTSNVVLLLGAIATAA
MAB_4577c|M.abscessus_ATCC_199 GSVSFWGSLVAFAKLQESIPKNVEKRLVASAKLFQASNIVLLLAAVGTAV
MMAR_0379|M.marinum_M GSISFWGSIIAFGKLQELISG----APIGFGKAQQPVNLLLLVGAVVAAV
MUL_4733|M.ulcerans_Agy99 GSISFWGSIIAFGKLQELISG----APIGFGKAQQPVNLLLLVGAVVAAV
MAV_5140|M.avium_104 GSISFWGSIIAFGKLQEVISG----APIGFGKAQQPINLLLLAGAVAAAV
MLBr_02634|M.leprae_Br4923 GSISFWGSIIAFGKLQETISG----FPIGFGKVQQPINLLLLVGAIVAAV
Mb0162|M.bovis_AF2122/97 GSISFWGSIVAFGKLQEIISG----RPIGLGKAQQPINLLLLAVAVAAAV
Rv0157|M.tuberculosis_H37Rv GSISFWGSIVAFGKLQEIISG----RPIGLGKAQQPINLLLLAVAVAAAV
TH_0162|M.thermoresistible__bu GSISFWGSLIAFGKLQEILPG----RPIGFGKVQQPFNILLLIGSVAACV
Mflv_0727|M.gilvum_PYR-GCK GAVTFTGSIVANLKLSAKMKS---APMMLPGKNFLNVGALVVFAALTVWF
Mvan_0119|M.vanbaalenii_PYR-1 GAVTFTGSIVANLKLSARIKS---APLMLPGKNILNVGALVVFIALTVWF
*:::* **::* **. : : .* . ::: :: .
MSMEG_0150|M.smegmatis_MC2_155 YIGLHAGT---GNPLWLIVVVLVLAGIMGLFVVFPIGGADMPVVISLLNA
MAB_4577c|M.abscessus_ATCC_199 YIGLHP-----GLPVWWIVAVLVFAGVMGLFVVFPIGGADMPVVISLLNA
MMAR_0379|M.marinum_M VIGLDAHPGSGGVSLWWMIGLLAAAGVLGLMVVLPIGGADMPVVISLLNA
MUL_4733|M.ulcerans_Agy99 VIGLDAYPGSGGVSLWWMIGLLAAAGVLGLMVVLPIGGADMPVVISLLNA
MAV_5140|M.avium_104 VIGLHAHPGSGGVSLWWMIGLLAAAGVLGLMVVLPIGGADMPVVISLLNA
MLBr_02634|M.leprae_Br4923 VIGLHAQPGSAGASLWWMIGLLVAAGVLGLMVVLSIGGADMPVVISLLNA
Mb0162|M.bovis_AF2122/97 VIGLHAHPGSGGVALWWMIGLLVAAGVLGLMVVLPIGGADMPVVISMLNA
Rv0157|M.tuberculosis_H37Rv VIGLHAHPGSGGVALWWMIGLLVAAGVLGLMVVLPIGGADMPVVISMLNA
TH_0162|M.thermoresistible__bu VIGLDAHPGTGGASLWWMIAVLVLAGVLGLMVVLPIGGADMPVVISMLNA
Mflv_0727|M.gilvum_PYR-GCK VI---------DPALWLLIVVTVLALLLGWHLVASIGGGDMPVVVSMLNS
Mvan_0119|M.vanbaalenii_PYR-1 VI---------DPQLWLLVVVTVLALALGWHLVASIGGGDMPVVVSMLNS
* . :* :: : . * :* :* .***.*****:*:**:
MSMEG_0150|M.smegmatis_MC2_155 LTGLSAAAAGLALNNTAMIVAGMIVGASGSILTNLMAVAMNRSIPAIVFG
MAB_4577c|M.abscessus_ATCC_199 MTGLSAAAAGLALNNTAMIVAGMIVGASGSILTNLMAVAMNRSIPAIVFG
MMAR_0379|M.marinum_M MTGLSAAAAGLALNNTAMIVAGMIVGASGSILTNLMAKAMNRSIPAIVAG
MUL_4733|M.ulcerans_Agy99 MTGLSAAAAGLALNNTAMIGAGMIVGASGSILTNLMAKAMNRSIPAIVAG
MAV_5140|M.avium_104 MTGLSAAAAGLALNNTAMIVAGMIVGASGSILTNLMAKAMNRSIPAIVAG
MLBr_02634|M.leprae_Br4923 MTGLSAAATGLALNNTAIIVAGMIVGASGSILTNLMAKAMNRSIPAIVAG
Mb0162|M.bovis_AF2122/97 MTGLSAAAAGLALNNTAMIVAGMIVGASGSILTNLMAKAMNRSIPAIVAG
Rv0157|M.tuberculosis_H37Rv MTGLSAAAAGLALNNTAMIVAGMIVGASGSILTNLMAKAMNRSIPAIVAG
TH_0162|M.thermoresistible__bu LTGLSAAAAGMALNNQAMIVAGMLVGASGSILTNLMAKAMNRSIPAIVAG
Mflv_0727|M.gilvum_PYR-GCK YSGWAAAAAGFLLGNDLLIVTGALVGSSGAYLSYIMCKAMNRSFISVIAG
Mvan_0119|M.vanbaalenii_PYR-1 YSGWAAAAAGFLLGNDLLIVTGALVGSSGAYLSYIMCKAMNRSFISVIAG
:* :***:*: *.* :* :* :**:**: *: :*. *****: ::: *
MSMEG_0150|M.smegmatis_MC2_155 SFGAGGDTAAVAGGEQGTAKSTSAADAAIQMAYANQVIVVPGYGLAVAQA
MAB_4577c|M.abscessus_ATCC_199 SFGGSDAGAAGGAAEQGTVKATSASDAAIQMAYANQVIVVPGYGLAVAQA
MMAR_0379|M.marinum_M GFGGGGVSPSADGGGDKHVKATSAADAAIQMAYANQVIVVPGYGLAVAQA
MUL_4733|M.ulcerans_Agy99 GFGGGGVSPSADGGGDKHVKATSAADAAIQMAYANQVIVVPGYGLAVAQA
MAV_5140|M.avium_104 GFGGGGVAPGGGDGGDKHVKSTSAADAAIQMAYANQVIVVPGYGLAVAQA
MLBr_02634|M.leprae_Br4923 GFGSGGVAPSRD--GDKQVKSTSAADAAIQMAYANQVIVVPGYGLAVAQA
Mb0162|M.bovis_AF2122/97 GFGGGGVAPSGG-GDDKHVKATSAADAAIQMAYANQVIVVPGYGLAVAQA
Rv0157|M.tuberculosis_H37Rv GFGGGGVAPSGG-GDDKHVKATSAADAAIQMAYANQVIVVPGYGLAVAQA
TH_0162|M.thermoresistible__bu GFGGGGGVGGDGDSGEKVVKSTSAADAAIQMAYANQVIIVPGYGLAVAQA
Mflv_0727|M.gilvum_PYR-GCK GFG--IEAGPAEDKDYGEHREITADGAAELLASASSVIITPGYGMAVAQA
Mvan_0119|M.vanbaalenii_PYR-1 GFG--IEAGPAEDKDYGEHREITAEGAAELLASASSVIITPGYGMAVAQA
.** : :* .** :* *..**:.****:*****
MSMEG_0150|M.smegmatis_MC2_155 QHAVKDMAAILESKGVEVKYAIHPVAGRMPGHMNVLLAEADVAYDAMKEM
MAB_4577c|M.abscessus_ATCC_199 QHTVKEMADLLESKGVEVKYAIHPVAGRMPGHMNVLLAEADVEYDAMKEM
MMAR_0379|M.marinum_M QHAVKDMASLLEDKGVAVKYAIHPVAGRMPGHMNVLLAEAEVDYDAMKDM
MUL_4733|M.ulcerans_Agy99 QHAVKDMASLLEDKGVAVKYAIHPVAGRMPGHMNVLLAEAEVDYDAMKDM
MAV_5140|M.avium_104 QHAVKDMAALLEEKGVPVKYAIHPVAGRMPGHMNVLLAEAEVDYDAMKDM
MLBr_02634|M.leprae_Br4923 QHVVKDMASLLENKGVPVSYAIHPVAGRMPGHMNVLLAEAEVDYDAMKDM
Mb0162|M.bovis_AF2122/97 QHAVKDLATLLEDRGVPVKYAIHPVAGRMPGHMNVLLAEAEVDYDAMKDM
Rv0157|M.tuberculosis_H37Rv QHAVKDLATLLEDRGVPVKYAIHPVAGRMPGHMNVLLAEAEVDYDAMKDM
TH_0162|M.thermoresistible__bu QHAVKDLSTLLESRGVPVKFGIHPVAGRMPGHMNVLLAEAEVDYDAMKDM
Mflv_0727|M.gilvum_PYR-GCK QYGVADLTRKLRERGVDVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEM
Mvan_0119|M.vanbaalenii_PYR-1 QYGVADLTRKLRDRGVDVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEM
*: * ::: *..:** * :.*******:***********.* ** : :*
MSMEG_0150|M.smegmatis_MC2_155 DDVNGEFSRTDVTLVIGANDVTNPAARNDPSSPIHGMPILNVDESKSVIV
MAB_4577c|M.abscessus_ATCC_199 DDINGEFNRTDVTIVIGANDVTNPAARNDPSSPIHGMPILNVDESRSVIV
MMAR_0379|M.marinum_M DDINDEFARTDVAIVIGANDVTNPAARNDASSPIYGMPILNVDKAKSVIV
MUL_4733|M.ulcerans_Agy99 DDINDEFARTDVAIVIGANDVTNPAARNDASSPIYGMPILNVDKAKSVIV
MAV_5140|M.avium_104 DDINDEFARTDVAIVIGANDVTNPAARNEASSPIYGMPILNVDKAKSVIV
MLBr_02634|M.leprae_Br4923 DDINDEFARTDVVIVIGANDVTNPAARNETASPIYGMPILNVDKAKSVIV
Mb0162|M.bovis_AF2122/97 DDINDEFARTDVTIVIGANDVTNPAARNETSSPIYGMPILNVDKSRSVIV
Rv0157|M.tuberculosis_H37Rv DDINDEFARTDVTIVIGANDVTNPAARNETSSPIYGMPILNVDKSRSVIV
TH_0162|M.thermoresistible__bu DEINDEFARTDVTVVIGANDVTNPAARNDPSSPIHGMPILNVDQSKSVIV
Mflv_0727|M.gilvum_PYR-GCK DEINDDFDGTSVVLVIGANDTVNPAASEDPSSPIAGMPVLTVWNADNVIV
Mvan_0119|M.vanbaalenii_PYR-1 DEINDDFDGTSVVLVIGANDTVNPAASEDPGSPIAGMPVLTVWNADNVIV
*::*.:* *.*.:******..**** ::..*** ***:*.* :: .***
MSMEG_0150|M.smegmatis_MC2_155 LKRSMSSGYAGIENPLFFLNHTSMLFGDAKKSVGEVIEELKAL---
MAB_4577c|M.abscessus_ATCC_199 LKRSMSSGYAGIENPLFFQPQTSMLFGDAKKSVSAVIEELKAL---
MMAR_0379|M.marinum_M LKRSMNSGFAGIDNPLFYGEGTTMLFGDAKKSVTEVAEELKAL---
MUL_4733|M.ulcerans_Agy99 LKRSMNSGFAGIDNPLFYGEGTTMLFGDAKKSVTEVAEELKAL---
MAV_5140|M.avium_104 LKRSMNSGFAGIDNPLFYAEGTTMLFGDAKKSVTEVAEELKAL---
MLBr_02634|M.leprae_Br4923 LKRSMNSGFAGIDNRLFYADGTTMLFGDAKQSVTEVTEELKVL---
Mb0162|M.bovis_AF2122/97 LKRSMNSGFAGIDNPLFYADGTTMLFGDAKKSVTEVSEELKAL---
Rv0157|M.tuberculosis_H37Rv LKRSMNSGFAGIDNPLFYADGTTMLFGDAKKSVTEVSEELKAL---
TH_0162|M.thermoresistible__bu LKRSMSSGFAGIDNPLFYAEGTTMLFGDAKKSVTEVIEELKAL---
Mflv_0727|M.gilvum_PYR-GCK FKRSMASGYAGVQNPLFFRENTQMLFGDAKDRVDAINAALSETAKV
Mvan_0119|M.vanbaalenii_PYR-1 FKRSMASGYAGVQNPLFFRENTQMLFGDAKDRVDAINAALSVAEHV
:**** **:**::* **: * *******. * : *.