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TAASDVTLGNTVDWQFAATVGERLARPGPPSSDYTRRQAVDELMRAAEQAEPPVRDVTGLITTGDVPAAR VVDRPEWIRAAAESMRAMTNGAEKPRGLLTGRITGAQTGAVLAFVASGILGQYDPFAAADAAGMGGLLLV YPNVIAVERQLRVDPSDFRLWVCLHEVAHRVQFTANPWLAGYMQQALGLLTTEPADDIGQVVSRLANFVR NRDDPGDDSGNVTGILGVVRAVQSEPQRQALDQLLALGTLLEGHAEHVMDAVGPMVVPSVAVIRRRFDER RQRKQPPLQRLLRALLGFDAKLNQYTRGKAFVDDVVARVGMKRFNTIWTSPQTLPLPAELENPRRWIDRV L*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_5126 | - | - | 100% (352) | hypothetical protein MMAR_5126 |
| M. marinum M | MMAR_1369 | - | 1e-11 | 22.66% (278) | hypothetical protein MMAR_1369 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3650c | - | 1e-163 | 81.02% (353) | hypothetical protein Mb3650c |
| M. gilvum PYR-GCK | Mflv_1410 | - | 1e-132 | 65.92% (358) | hypothetical protein Mflv_1410 |
| M. tuberculosis H37Rv | Rv3626c | - | 1e-163 | 81.02% (353) | hypothetical protein Rv3626c |
| M. leprae Br4923 | MLBr_00642 | - | 9e-11 | 20.71% (280) | hypothetical protein MLBr_00642 |
| M. abscessus ATCC 19977 | MAB_0520 | - | 1e-128 | 65.24% (351) | hypothetical protein MAB_0520 |
| M. avium 104 | MAV_0530 | - | 1e-157 | 76.75% (357) | hypothetical protein MAV_0530 |
| M. smegmatis MC2 155 | MSMEG_6112 | - | 1e-134 | 66.95% (357) | hypothetical protein MSMEG_6112 |
| M. thermoresistible (build 8) | TH_1411 | - | 1e-136 | 64.55% (378) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4202 | - | 0.0 | 99.43% (352) | hypothetical protein MUL_4202 |
| M. vanbaalenii PYR-1 | Mvan_5379 | - | 1e-135 | 67.60% (358) | hypothetical protein Mvan_5379 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_5126|M.marinum_M ----------------------------------------------MTAA
MUL_4202|M.ulcerans_Agy99 ----------------------------------------------MTAA
Mb3650c|M.bovis_AF2122/97 ----------------------------------------------MTGA
Rv3626c|M.tuberculosis_H37Rv ----------------------------------------------MTGA
MAV_0530|M.avium_104 ----------------------------------------------MTPA
MSMEG_6112|M.smegmatis_MC2_155 -----------------------------------------------MSR
TH_1411|M.thermoresistible__bu -------------------------------------------VPDMTSE
Mflv_1410|M.gilvum_PYR-GCK ------------------------------------MPLMTPKTKSDSGT
Mvan_5379|M.vanbaalenii_PYR-1 --------------------------------------------MSSSSK
MAB_0520|M.abscessus_ATCC_1997 ---------------------------------MAESGRVVQSGGVGTKS
MLBr_00642|M.leprae_Br4923 MAHSGSPVSTVDGVANPPFGFSSGNDSPNDESGRDKHGKNGPDSGSSGSD
MMAR_5126|M.marinum_M SDVTLGNTVDWQFAAT------VGERLARP----------GPPSSDYTRR
MUL_4202|M.ulcerans_Agy99 SDVTLGNTVDWQFAAT------VGERLARP----------GPPSSDYTRR
Mb3650c|M.bovis_AF2122/97 SELTLGNTVDWEFAAS------VGERLARP----------APPSTEYTRR
Rv3626c|M.tuberculosis_H37Rv SELTLGNTVDWEFAAS------VGERLARP----------APPSTEYTRR
MAV_0530|M.avium_104 PDLTLGTAVDWRFAAT------VGRRLARP----------GPPSTDYTRR
MSMEG_6112|M.smegmatis_MC2_155 PTMTAGRAVDWDFAAS------VGAKLARP----------EPPSTDYTRR
TH_1411|M.thermoresistible__bu RRLTVGRAVDWEFAAD------VGARLARP----------GPTTTDYTRR
Mflv_1410|M.gilvum_PYR-GCK SRFSVGHAVDWNLAAT------VGGKLARQ----------EPKATDYTRR
Mvan_5379|M.vanbaalenii_PYR-1 SGFTVGRAVDWKLAAT------LGGKLARP----------EPPATDYTRK
MAB_0520|M.abscessus_ATCC_1997 PELTVGRMVNWEFAAT------VGVKLARP----------APPTTEYTRR
MLBr_00642|M.leprae_Br4923 PLASFGMSGDFGMSDLGQIFTHLGQMFTNAGTAMTADKQLGPVNYELARR
: * :: :: :* ::. * : :*:
MMAR_5126|M.marinum_M QAVDELMRAAEQ---AEPPVRDVTGLITT-----GDVPAARVVDR----P
MUL_4202|M.ulcerans_Agy99 QAVDELMRAAEQ---AEPPVRDVTGLITT-----GDVPAGRVVDR----P
Mb3650c|M.bovis_AF2122/97 QVIDELTVAAEK---AEPPVRDVTGLIAD-----GVVPPARVVDR----P
Rv3626c|M.tuberculosis_H37Rv QVIDELTVAAEK---AEPPVRDVTGLIAD-----GVVPPARVVDR----P
MAV_0530|M.avium_104 QVIDELAGAATK---AEPLVRQVTGLLTDGAD-DGRVPAARIVDR----P
MSMEG_6112|M.smegmatis_MC2_155 QAIDQLSESARA---AELPVREVTGLNEG-----AEVPEARVVDR----P
TH_1411|M.thermoresistible__bu QAIEQLAELSRT---AEVPVREVTGLIEG-----DEIPEARIVDR----P
Mflv_1410|M.gilvum_PYR-GCK QAIEQLAQSARD---SEIPVREVTGLIEG-----GEIPEARIVNR----P
Mvan_5379|M.vanbaalenii_PYR-1 QAFEQLAEAARA---SELPVREVTGLIEG-----GEIPEARIVNR----P
MAB_0520|M.abscessus_ATCC_1997 QAIAELSDAARR---AETPVREVTGLADG-----LLVPEARVIDR----P
MLBr_00642|M.leprae_Br4923 VASSSIGFVAPIPATTSSAIGDAVHLAETWLDGVTALPAGTTKAEGWTPD
. .: : :. : :.. * :* . .
MMAR_5126|M.marinum_M EWIRAAAESMRAMTN-------------GAEKPRG----------LLTGR
MUL_4202|M.ulcerans_Agy99 EWIRAAAESMRAMTN-------------GAEKPRG----------LLTGR
Mb3650c|M.bovis_AF2122/97 AWIRSAAESMRAMTH-------------GSAKPRG----------FLTGR
Rv3626c|M.tuberculosis_H37Rv AWIRSAAESMRAMTH-------------GSAKPRG----------FLTGR
MAV_0530|M.avium_104 EWIAAAAESMRVMMN-------------GTERPRG----------FLTGR
MSMEG_6112|M.smegmatis_MC2_155 AWIRAATRSMRVMTT-------------GGDTGDS--DANGDKPGFITGR
TH_1411|M.thermoresistible__bu QWIRAASASMRVMTG-------------GATSADTNGEKSGAAAGFIAGK
Mflv_1410|M.gilvum_PYR-GCK DWIRAAAQSMRAMTG-------------GAHDGDV-------KPRMITGR
Mvan_5379|M.vanbaalenii_PYR-1 EWIHAAAQSMRAMTG-------------GGHADDV-------KPRAVTGR
MAB_0520|M.abscessus_ATCC_1997 GWISAAAQSMRLMAG-------------GGEGATG----------FLSGR
MLBr_00642|M.leprae_Br4923 DWVNNTLETWKRLCDPMAQQISTVWAASLPEEAKSMASPLLSMMSQMGGM
*: : : : : : *
MMAR_5126|M.marinum_M ITGAQTGAVLAFVASGILGQYDPFAA----------------ADAAGMGG
MUL_4202|M.ulcerans_Agy99 ITGAQTGAVLAFVASGILGQYDPFAA----------------ADGAGMGG
Mb3650c|M.bovis_AF2122/97 ITGAQTGAVLAFVASGILGQYDPFG-------------------AAGEGC
Rv3626c|M.tuberculosis_H37Rv ITGAQTGAVLAFVASGILGQYDPFG-------------------AAGEGC
MAV_0530|M.avium_104 VTGAQTGAVLAYVSSGILGQYDPFAT----------------DRGAGAGC
MSMEG_6112|M.smegmatis_MC2_155 VTGAQTGAVLAFISSGILGQYDPFGP--------------------DGGE
TH_1411|M.thermoresistible__bu LTGAQTGAVLAFISSGILGQYDPFAPRGRERGADGGRAGDDPGGPRSGGE
Mflv_1410|M.gilvum_PYR-GCK VAGAQTGAVLAFVSSGILGQYDPFS---------------------GDGE
Mvan_5379|M.vanbaalenii_PYR-1 IAGAQTGAVLAFVSSGILGQYDPFAV--------------------GGGE
MAB_0520|M.abscessus_ATCC_1997 VTGAQTGAVLAFVSSGILGQYDPFTA-------------------DGAGA
MLBr_00642|M.leprae_Br4923 AFGSQLGQAFGQLSREVLTSTDIGLP------------------LGPRGV
*:* * .:. :: :* . * *
MMAR_5126|M.marinum_M LLLVYPNVIAVERQLRVDPSDFRLWVCLHEVAHRVQFTANPWLAGYMQQA
MUL_4202|M.ulcerans_Agy99 LLLVYPNVIAVERQLRVDPSDFRLWVCLHEVAHRVQFTANPWLAGYMQQA
Mb3650c|M.bovis_AF2122/97 LLLVYPNVIAVERQLRVEPSDFRLWVCLHEVTHRVQFTANPWLSGYMSQA
Rv3626c|M.tuberculosis_H37Rv LLLVYPNVIAVERQLRVEPSDFRLWVCLHEVTHRVQFTANPWLSGYMSQA
MAV_0530|M.avium_104 LLLVYPNVIAVERQLRIEPSDFRLWVCLHEVTHRVQFTANPWLPGYMSQA
MSMEG_6112|M.smegmatis_MC2_155 LLLVYPNVISVERQLRVAPADFRLWVCLHEVTHRVQFRANPWLADHMSQA
TH_1411|M.thermoresistible__bu LLLVYPNVIAVERQLRVVPADFRLWVCLHEVTHRVQFRANPWLAEHMSRA
Mflv_1410|M.gilvum_PYR-GCK LLLVYPNVIAVERQLRVVPEDFRMWVCLHEVTHRVQFRANPWLAEHMSGA
Mvan_5379|M.vanbaalenii_PYR-1 LLLVYPNVIAVERQLRVAPKDFRMWVCLHEVTHRVQFRANPWLADHMSKA
MAB_0520|M.abscessus_ATCC_1997 LLLVYPNVIAVERQLRVVPSDFRMWVCLHEVTHRVQFSANPWLADYMSGT
MLBr_00642|M.leprae_Br4923 AAIMPQAVESFADGLEQPRCEILTFLATREAAHHRLFSHVPWLASQLLGA
:: * :. *. :: ::. :*.:*: * ***. : :
MMAR_5126|M.marinum_M LGLLTTEPADDIGQVVSRLANFVRNRDDP--GDDS-GNVTGILGVVRAVQ
MUL_4202|M.ulcerans_Agy99 LGLLTTEPADDIGQVVSRLANFVRNRDDP--GDDS-GNVTGILGVVRAVQ
Mb3650c|M.bovis_AF2122/97 LNLLTFEPVDDIGRVVSRLADFIRSRGHG--TDDSEVNPSGILGLVRAVQ
Rv3626c|M.tuberculosis_H37Rv LNLLTFEPVDDIGRVVSRLADFIRSRGHG--TDDSEVNPSGILGLVRAVQ
MAV_0530|M.avium_104 LALLTRDTGDDLGQVLSRLADYARNRGNT--ASQADANSTGILGLVRAVQ
MSMEG_6112|M.smegmatis_MC2_155 LAVLTQDAGDDVAALAGRLAQYVRDQRGT-NGSAPEPNSTGILGLMRAVQ
TH_1411|M.thermoresistible__bu LAVLTQDVTEEATAVIARLAEFLRNRR---TYVETEPNSTGVLGLVRAVQ
Mflv_1410|M.gilvum_PYR-GCK LAVLTEDGGEDLTAMVGRLADYVRDHQVVVKNGEPELNSTGIIGLLRAVQ
Mvan_5379|M.vanbaalenii_PYR-1 LAVLTEDAGEDLPQVVGRLVDYVRDREVVVKNSEPAMNSTGVLGLLRAVQ
MAB_0520|M.abscessus_ATCC_1997 LATLAHEQEEDVAGMLGRLADFVRSSRSQ--------GHNGIVELLRAMQ
MLBr_00642|M.leprae_Br4923 VEAYAAGMKIDMNGIEELARDFNPASLSD----PTAIEELLGQGVFEPQA
: : : : :: :...
MMAR_5126|M.marinum_M SEPQRQALDQLLALGTLLEGHAEHVMDAVGPMVVPSVAVIRRRFDERRQR
MUL_4202|M.ulcerans_Agy99 SEPQRQALDQLLALGTLLEGHAEHVMDAVGPMVVPSVAVIRRRFDERRQR
Mb3650c|M.bovis_AF2122/97 SEPQRKALDQLLVLGTLLEGHAEHVMDAVGPMVVPSVATIRRRFDDRRHH
Rv3626c|M.tuberculosis_H37Rv SEPQRKALDQLLVLGTLLEGHAEHVMDAVGPMVVPSVATIRRRFDDRRHH
MAV_0530|M.avium_104 SEPQRQALDQLLVLGTLLEGHADHVMDAVGPMAVPSVATIRRRFDERRHR
MSMEG_6112|M.smegmatis_MC2_155 AEPQRRALDQLLVLGTLLEGHADHVMDAVGPAVVPTVGTIRRRFDERRQR
TH_1411|M.thermoresistible__bu AEPQRRALDQLLVLGTLLEGHAEHVMDAVGPAVVPTVSVIRRRFDERRQR
Mflv_1410|M.gilvum_PYR-GCK SEPQRQALDRLLVLGTLLEGHAEHVMDAVGPAVVPSVATIRQRFDQRRQR
Mvan_5379|M.vanbaalenii_PYR-1 SEPQREALDRLLVLGTLLEGHAEHVMDAVGPAVVPSVASIRHRFDQRRQR
MAB_0520|M.abscessus_ATCC_1997 SDSGRDALDRLLVLGTLLEGHADHVMDAVGPAVVPSVASIRSRFEARRSR
MLBr_00642|M.leprae_Br4923 TPAQTQALERLEALLALIEGWVQVVVTAALGDRIPGAAALGETLRRRRAS
: . **::* .* :*:** .: *: *. :* .. : : **
MMAR_5126|M.marinum_M KQPPLQRLLRALLGFDAKLNQYTRGKAFVDDVVARVGMKRFNTIWTSPQT
MUL_4202|M.ulcerans_Agy99 KQPPLQRLLRALLGFDAKLNQYTRGKAFVDDVVARVGMKRFNTIWTSPQT
Mb3650c|M.bovis_AF2122/97 KQPPLQRLVRALLGFDAKLSQYTRGKAFVDHVVDRAGMKLFNTIWSGPET
Rv3626c|M.tuberculosis_H37Rv KQPPLQRLVRALLGFDAKLSQYTRGKAFVDHVVDRAGMKLFNTIWSGPET
MAV_0530|M.avium_104 KQPPLQRLLRALLGLDAKLSQYTRGKAFVDQVVGRVGMARFNAVWTGPET
MSMEG_6112|M.smegmatis_MC2_155 KQPPVQRIVRALLGFDAKLSQYTRGKAFVDHVVSAVGMQRFNTVWTNAET
TH_1411|M.thermoresistible__bu RQPPLQRLVRALLGVDAKISQYTRGKAFVDHVVAKVGMDRFNRVWESPET
Mflv_1410|M.gilvum_PYR-GCK KQPPLQRLLRILLGVDAKMSQYTKGKAFVDEVVGTVGMERFNAIWTDADT
Mvan_5379|M.vanbaalenii_PYR-1 RQPPLQRLLRALLGVDAKMSQYTRGKAFVDHVVAEVGMQRFNAIWTDAET
MAB_0520|M.abscessus_ATCC_1997 KQPPLQRIIRALIGMDAKMRQYTRGKKFVDHVVGKVGMERFNTIWRDPQT
MLBr_00642|M.leprae_Br4923 GGP-AEQTFATLVGLELRPRKLREAAVLWERLTQAAGVDARDAVWQHPDL
* :: . *:*.: : : .. : : :. .*: : :* .:
MMAR_5126|M.marinum_M LPLPAELENPRRWIDRVL--------------------------------
MUL_4202|M.ulcerans_Agy99 LPLPAELENPRRWIDRVL--------------------------------
Mb3650c|M.bovis_AF2122/97 LPLPAEIENPQRWIDRVL--------------------------------
Rv3626c|M.tuberculosis_H37Rv LPLPAEIENPQRWIDRVL--------------------------------
MAV_0530|M.avium_104 LPLPVEIEEPQRWIDRVL--------------------------------
MSMEG_6112|M.smegmatis_MC2_155 LPLPTEIDEPQRWIDRVL--------------------------------
TH_1411|M.thermoresistible__bu LPLPAEIEEPHRWIDRVL--------------------------------
Mflv_1410|M.gilvum_PYR-GCK LPQPQEIDEPQRWIDRVL--------------------------------
Mvan_5379|M.vanbaalenii_PYR-1 LPKPAEIDEPQRWIDRVL--------------------------------
MAB_0520|M.abscessus_ATCC_1997 LPQPAEIEDPDQWIDRVL--------------------------------
MLBr_00642|M.leprae_Br4923 LPSGKDLDDPASFIDRIIGGDTSGIDEAIAKLDLDRGNSDGRTPGSGGPV
** ::::* :***::
MMAR_5126|M.marinum_M --
MUL_4202|M.ulcerans_Agy99 --
Mb3650c|M.bovis_AF2122/97 --
Rv3626c|M.tuberculosis_H37Rv --
MAV_0530|M.avium_104 --
MSMEG_6112|M.smegmatis_MC2_155 --
TH_1411|M.thermoresistible__bu --
Mflv_1410|M.gilvum_PYR-GCK --
Mvan_5379|M.vanbaalenii_PYR-1 --
MAB_0520|M.abscessus_ATCC_1997 --
MLBr_00642|M.leprae_Br4923 DN