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PFPRRWRGLLELLLLTSELYPDPVLPSLSLLPHNVRTAPAEASSLLEAGNADAVLVDARNDLSAARGLCR LLSTAGRSVPVLAVVNEGGLVAVSADWGLDEILLPSTGPAEIDARLRLVVGRRGGQADQESVGKVSLGEL VIDEGTYTARLRGRPLDLTYKEFELLKYLAQHAGRVFTRAQLLHEVWGYDFFGGTRTVDVHVRRLRAKLG PEHEALIGTVRNVGYKAVRPARGRSVAVEADDEEAESDHDGYEEPLVDPLRSP*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_4865 | - | - | 100% (264) | transcriptional regulatory protein |
M. marinum M | MMAR_1825 | - | 3e-46 | 43.29% (231) | transcriptional regulatory protein |
M. marinum M | MMAR_0816 | regX3 | 7e-25 | 37.06% (197) | two-component sensory transduction protein RegX3 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0841 | - | 1e-130 | 90.94% (254) | transcriptional regulatory protein |
M. gilvum PYR-GCK | Mflv_1650 | - | 1e-112 | 76.30% (270) | response regulator receiver protein |
M. tuberculosis H37Rv | Rv0818 | - | 1e-129 | 90.55% (254) | transcriptional regulatory protein |
M. leprae Br4923 | MLBr_02439 | - | 2e-24 | 36.55% (197) | putative two-component system response regulator |
M. abscessus ATCC 19977 | MAB_0744 | - | 1e-101 | 74.60% (252) | transcriptional regulatory protein |
M. avium 104 | MAV_0760 | - | 1e-121 | 84.94% (259) | transcriptional regulatory protein |
M. smegmatis MC2 155 | MSMEG_5784 | - | 1e-108 | 79.67% (241) | transcriptional regulatory protein |
M. thermoresistible (build 8) | TH_4312 | - | 3e-25 | 37.10% (186) | PUTATIVE two component transcriptional regulator, winged helix |
M. ulcerans Agy99 | MUL_0435 | - | 1e-142 | 98.82% (255) | transcriptional regulatory protein |
M. vanbaalenii PYR-1 | Mvan_5097 | - | 1e-111 | 77.44% (266) | response regulator receiver protein |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_4865|M.marinum_M -----MPFPRRWRGLLELLLLTSELYPDPVLPSLSLLPHNVRTAPAEASS MUL_0435|M.ulcerans_Agy99 --------------MLELLLLTSELYPDPVLPSLSLLPHNVRTAPAEASS Mb0841|M.bovis_AF2122/97 --------------MLELLLLTSELYPDPVLPALSLLPHTVRTAPAEASS Rv0818|M.tuberculosis_H37Rv --------------MLELLLLTSELYPDPVLPALSLLPHTVRTAPAEASS MAV_0760|M.avium_104 ---------------MELLLLTPELHPDPVLPSLSLLAHTVRTAPPEPSS Mflv_1650|M.gilvum_PYR-GCK MRCPGERAPRLLEGQLDLLLLTVDPHPESVLPSLSLLAHAVRTAPTEVSS Mvan_5097|M.vanbaalenii_PYR-1 ---------------MDLLLLTVDPHPESVLPSLALLAHNVRTAPTEVSS MSMEG_5784|M.smegmatis_MC2_155 ---------------MDLLLLTVDPHPESVLPSLSLLAHTVRTAPTEVSS MAB_0744|M.abscessus_ATCC_1997 ----------MLEGSLDLLLLTADPNPDGVLPSLSLLAHTVRPVPSEVSS MLBr_02439|M.leprae_Br4923 ----------------------------------------MVTDGPAALA TH_4312|M.thermoresistible__bu -----------MTSVLIVEDEESLADPLAFLLRKEGFETTIVTDGPSALA : . . : MMAR_4865|M.marinum_M LLEAGNADAVLVDARNDLSAARGLCRLLSTAGRSVPVLAVVNEGG--LVA MUL_0435|M.ulcerans_Agy99 LLEAGNADAVLADARNDLSAARGLCRLLSTAGRSVPVLAVVNEGG--LVA Mb0841|M.bovis_AF2122/97 LLEAGNADAVLVDARNDLSSGRGLCRLLSSTGRSIPVLAVVSEGG--LVA Rv0818|M.tuberculosis_H37Rv LLEAGNADAVLVDARNDLSSGRGLCRLLSSTGRSIPVLAVVSEGG--LVA MAV_0760|M.avium_104 LLEAGTADAVIVDARTDLSSARGLCRLLSTAGRSVPVLAVVSEGG--LVA Mflv_1650|M.gilvum_PYR-GCK LLEAGTADVAIVDARTDLAAARGLCRLLGTTGTSVPVVAVVNEGG--LVA Mvan_5097|M.vanbaalenii_PYR-1 LLEAGTADVAIVDARTDLAAARGLCRLLGTTGTSVPVVAVVNEGG--LVA MSMEG_5784|M.smegmatis_MC2_155 LLETGSADVAIVDARTDLAAARGLCRLLGTTGTSVPVVAVINEGG--LVA MAB_0744|M.abscessus_ATCC_1997 LLEAGAADVAIVDARTDLASARGLCRLLGAAGSSVPVVAVVNEGS--LVA MLBr_02439|M.leprae_Br4923 EFDRSGADIVLLDLMLPGMSGTDVYKQLRVR-SSVPVIMVTARDSEIDKV TH_4312|M.thermoresistible__bu EFERSGADIILLDLMLPGMSGTDVCRRLRAK-SKVPVIMVTARDSEIDKV :: . ** : * :. .: : * .:**: * ... . MMAR_4865|M.marinum_M VSADWGLDEILLPSTGPAEIDARLRLVVGRRGGQADQESVG-KVSLGELV MUL_0435|M.ulcerans_Agy99 VSADWGLDEILLPSTGPAEIDARLRLVVGRRGGQADQESVG-KVSLGELV Mb0841|M.bovis_AF2122/97 VSADWGLDEILLPSTGPAEIDARLRLVVGRRGDLADQESLG-KVSLGELV Rv0818|M.tuberculosis_H37Rv VSADWGLDEILLLSTGPAEIDARLRLVVGRRGDLADQESLG-KVSLGELV MAV_0760|M.avium_104 VNSDWGLDEILLPTTGPAEVDARLRLVVGRRGGLADQESAG-KVTLGELV Mflv_1650|M.gilvum_PYR-GCK VNVEWGLDEILLPSTGPAEIDARLRLLVGRRGGMANQENLG-KISLGELV Mvan_5097|M.vanbaalenii_PYR-1 VNVEWGLDEILLPSTGPAEIDARLRLLVGRRGGMANQENLG-KISLGELV MSMEG_5784|M.smegmatis_MC2_155 VNHEWGLDEILLPSTGPAEIDARLRLLVGRRGGNANQENVG-KITLGELV MAB_0744|M.abscessus_ATCC_1997 VNVDWGLDDILLPGTGPAEIDARLRLLVGRRAGAVNVENAS-KVVLGELV MLBr_02439|M.leprae_Br4923 VGLELGADDYVTKPYSARELIARIRAVLRRGGDDD-SEISDGVLESGPLR TH_4312|M.thermoresistible__bu VGLELGADDYVTKPYSARELIARIRAVLRRGSDLDGADVDDSVLEAGPVR *. : * *: : .. *: **:* :: * .. : . : * : MMAR_4865|M.marinum_M IDEGTYTARLRGRPLDLTYKEFELLKYLAQHAGRVFTRAQLLHEVWGYDF MUL_0435|M.ulcerans_Agy99 IDEGTYTARLRGRPLDLTYKEFELLKYLAQHAGRVFTRAQLLHEVWGYDF Mb0841|M.bovis_AF2122/97 IDEGTYTARLRGRPLDLTYKEFELLKYLAQHAGRVFTRAQLLHEVWGYDF Rv0818|M.tuberculosis_H37Rv IDEGTYTARLRGRPLDLTYKEFELLKYLAQHAGRVFTRAQLLHEVWGYDF MAV_0760|M.avium_104 IDEGTYTARLRGRPLDLTYKEFELLKYLAQHAGRVFTRAQLLHEVWGYDF Mflv_1650|M.gilvum_PYR-GCK IDEGTYTARLRGRPLDLTYKEFELLKYLAQHAGRVFTRAQLLQEVWGYDF Mvan_5097|M.vanbaalenii_PYR-1 IDEGTYTARLRGRPLDLTYKEFELLKYLAQHAGRVFTRAQLLQEVWGYDF MSMEG_5784|M.smegmatis_MC2_155 IDEGTYTARLRGKPLDLTYKEFELLKYLAQHAGRVFTRAQLLQEVWGYDF MAB_0744|M.abscessus_ATCC_1997 IDEGTYTARLRGRPLDLTYKEFELLKYLAQHAGRVFTRAQLLQEVWGYDF MLBr_02439|M.leprae_Br4923 MDVERHVVSVNGYAITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGVDY TH_4312|M.thermoresistible__bu MDVDRHVVTVRGEPITLPLKEFELLEYLLRNSGRVLTRGQLIDRVWGADY :* :.. :.* .: *. ***:**:** :::***:**.**:..*** *: MMAR_4865|M.marinum_M FGGTRTVDVHVRRLRAKLG--PEHEALIGTVRNVGYKAVRPARGR-SVAV MUL_0435|M.ulcerans_Agy99 FGGTRTVDVHVRRLRAKLG--PEHEALIGTVRNVGYKAVRPARGR-SVAV Mb0841|M.bovis_AF2122/97 FGGTRTVDVHVRRLRAKLG--PEHEALIGTVRNVGYKAVRPARGR-PPAA Rv0818|M.tuberculosis_H37Rv FGGTRTVDVHVRRLRAKLG--PEHEALIGTVRNVGYKAVRPARGR-PPAA MAV_0760|M.avium_104 FGGTRTVDVHVRRLRAKLG--PEYEALIGTVRNVGYKAVRPARGR-PPVA Mflv_1650|M.gilvum_PYR-GCK FGGTRTVDVHVRRLRAKLG--PEYESLIGTVRNVGYKAVRPARGR-PPAP Mvan_5097|M.vanbaalenii_PYR-1 FGGTRTVDVHVRRLRAKLG--PEYEALIGTVRNVGYKAVRPARGR-APAA MSMEG_5784|M.smegmatis_MC2_155 FGGTRTVDVHVRRLRAKLG--PEYEALIGTVRNVGYKAVRPSRGK-PPAA MAB_0744|M.abscessus_ATCC_1997 FGGTRTVDVHVRRLRAKLG--GEYESLIGTVRNVGYKAVRPPRAKGEPGP MLBr_02439|M.leprae_Br4923 VGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLES---------- TH_4312|M.thermoresistible__bu VGDTKTLDVHVKRLRSKIEEDPANPVHLVTVRGLGYKLEG---------- .*.*:*:****:***:*: : ***.:*** MMAR_4865|M.marinum_M EADDEEAESD-------------HDGYEEPLVDPLRSP MUL_0435|M.ulcerans_Agy99 DADDEETESD-------------HDGYEEPLVDPLRSP Mb0841|M.bovis_AF2122/97 DPDDEDADPG-------------RDGMQEPLVDPLRSQ Rv0818|M.tuberculosis_H37Rv DPDDEDADPG-------------RDGMQEPLVDPLRSQ MAV_0760|M.avium_104 EADDAESESDSASES-------DAEDVHDPLVDPLHTQ Mflv_1650|M.gilvum_PYR-GCK --ESEADDLD-DDPYADDE-PLASDEVPQALGDALRSP Mvan_5097|M.vanbaalenii_PYR-1 GADLPSDDLDGDDPYEDGVGSLDRDGVPEALGDALRSQ MSMEG_5784|M.smegmatis_MC2_155 --DASGEDVP-DGPDEGFG---DDVDVDGPLAGRLTSQ MAB_0744|M.abscessus_ATCC_1997 SAADDDDESDIDDLDDDGT----DQDIASEPG-AINAG MLBr_02439|M.leprae_Br4923 -------------------------------------- TH_4312|M.thermoresistible__bu --------------------------------------