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SDTDDTATLKYPGGEIDLQIAHATEGADGIALGPLLSKTGHTTFDNGFVNTASCKSSITYIDGDAGILRY RGYPIDQLAEKSTFIEVCYLLIYGELPNTDQLAQFTGRIQRHTMLHEDLKRFFDGFPRNAHPMPVLSSVV NALSAYYQDALDPMDSEQVELSTIRLLAKLPTIAAYAYKKSVGQPFLYPENSLTLVENFLRMTFGFPAEP YHPDPEVVRALDMLFILHADHEQNCSTSTVRLVGSSRANLFTSISGGINALWGPLHGGANQAVLEMLEQI RDSGDDVSEFVRKVKNREAGVKLMGFGHRVYKNYDPRARIVKEQADKILSKLGGDDSLLGIAKELEEAAL TDDYFIERKLYPNVDFYTGLIYRALGFPTRMFTVLFALGRLPGWIAHWREMHDEGDSKIGRPRQIYTGYT ERDYVAMDGR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_4640 | gltA | - | 100% (431) | citrate synthase I GltA2 |
M. marinum M | MMAR_1381 | gltA1 | 5e-50 | 32.71% (376) | citrate synthase I GltA1 |
M. marinum M | MMAR_4643 | citA | 4e-37 | 31.28% (390) | citrate synthase II CitA |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0920 | gltA | 0.0 | 95.13% (431) | type II citrate synthase |
M. gilvum PYR-GCK | Mflv_1729 | gltA | 0.0 | 84.91% (424) | type II citrate synthase |
M. tuberculosis H37Rv | Rv0896 | gltA | 0.0 | 95.36% (431) | type II citrate synthase |
M. leprae Br4923 | MLBr_02130 | gltA | 0.0 | 90.26% (431) | type II citrate synthase |
M. abscessus ATCC 19977 | MAB_0944 | gltA | 0.0 | 84.47% (425) | type II citrate synthase |
M. avium 104 | MAV_0344 | - | 1e-46 | 32.34% (368) | methylcitrate synthase |
M. smegmatis MC2 155 | MSMEG_5672 | gltA | 0.0 | 85.35% (430) | type II citrate synthase |
M. thermoresistible (build 8) | TH_3084 | - | 0.0 | 85.81% (430) | PUTATIVE citrate synthase I |
M. ulcerans Agy99 | MUL_0255 | gltA | 0.0 | 99.30% (431) | type II citrate synthase |
M. vanbaalenii PYR-1 | Mvan_5022 | gltA | 0.0 | 85.14% (424) | type II citrate synthase |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_4640|M.marinum_M MSDT----DDTATLKYPGGEIDLQIAHATEGADGIALGPLLSKTGHTTFD MUL_0255|M.ulcerans_Agy99 MSDT----DDTATLKYPGGEIDLQIAHATEGADGIALGPLLSKTGHTTFD Mb0920|M.bovis_AF2122/97 MADT----DDTATLRYPGGEIDLQIVHATEGADGIALGPLLAKTGHTTFD Rv0896|M.tuberculosis_H37Rv MADT----DDTATLRYPGGEIDLQIVHATEGADGIALGPLLAKTGHTTFD MLBr_02130|M.leprae_Br4923 MADT----DDTVTLKYPGGEIDLQIVRATEGNDGIAIVPVLAKTGYTTFD Mflv_1729|M.gilvum_PYR-GCK MADNAEAGQEHATLSYPGGELELDIVKASEGSDGIALGSLLAKTGYTTFD Mvan_5022|M.vanbaalenii_PYR-1 MADNADAGQEHATLVYPGGELELDIVKASEGADGIALGSLLAKSGYTTFD MSMEG_5672|M.smegmatis_MC2_155 MAEKPSNGQEHATVKYPGGELDLEIVHATEGADGIALGSLLAKTGYTTYD MAB_0944|M.abscessus_ATCC_1997 MADN----NDFATLQYPGGETKLDIVRATEGADGFALGKLLADTGYTTFD TH_3084|M.thermoresistible__bu VAENASSGDKHATLIYPGGQIDLEIVRATEGADGIALGSMLAETGYTTFD MAV_0344|M.avium_104 --------------------------------------MSTLEDNQPRIH . . . . MMAR_4640|M.marinum_M NGFVNTASCKSSITYIDGDAGILRYRGYPIDQLAEKSTFIEVCYLLIYGE MUL_0255|M.ulcerans_Agy99 NGFANTASCKSSITYIDGDAGILRYRGYPIDQLAEKSTFIEVCYLLIYGE Mb0920|M.bovis_AF2122/97 VGFANTAAAKSSITYIDGDAGILRYRGYPIDQLAEKSTFIEVCYLLIYGE Rv0896|M.tuberculosis_H37Rv VGFANTAAAKSSITYIDGDAGILRYRGYPIDQLAEKSTFIEVCYLLIYGE MLBr_02130|M.leprae_Br4923 VGYGNTASTKSSITYIDGDAGILRYRGYPIEQLAEKSTFIEVCYLLIYGE Mflv_1729|M.gilvum_PYR-GCK GGFVNTASTKSAITYIDGDAGILRYRGYPIEQLAEKSTFIEVSYLLIYGE Mvan_5022|M.vanbaalenii_PYR-1 GGFVNTASTKSAITYIDGDAGILRYRGYPIEQLAEKSNFIEVSYLLIYGE MSMEG_5672|M.smegmatis_MC2_155 GGFVNTASTKSAITYIDGDAGILRYRGYPIEQLAEKSTFIEVSYLLIYGE MAB_0944|M.abscessus_ATCC_1997 AGFVNTASTKSAITYIDGDAGILRYRGYPIEQLADKSTFIEVSYLLIYGE TH_3084|M.thermoresistible__bu SGFVNTASTKSSITYIDGEAGILRYRGYPIEQLAEKSTFIEVCFLLIYGE MAV_0344|M.avium_104 KGLAGVVVDTTAISKVVPETNSLTYRGYAVQDLAAHCSFEQVAYLLWYGE * ... .::*: : ::. * ****.:::** :..* :*.:** *** MMAR_4640|M.marinum_M LPNTDQLAQFTGRIQRHTMLHEDLKRFFDGFPRNAHPMPVLSSVVNALSA MUL_0255|M.ulcerans_Agy99 LPNTDQLAQFTGRIQRHTMLHEDLKRFFDGFPRNAHPMPVLSSVVNALSA Mb0920|M.bovis_AF2122/97 LPDTDQLAQFTGRIQRHTMLHEDLKRFFDGFPRNAHPMPVLSSVVNALSA Rv0896|M.tuberculosis_H37Rv LPDTDQLAQFTGRIQRHTMLHEDLKRFFDGFPRNAHPMPVLSSVVNALSA MLBr_02130|M.leprae_Br4923 LPATDQLAEFTHRIQRHTMLHEDLKRFYDGFPRNAHPMPVLSSVVNALSA Mflv_1729|M.gilvum_PYR-GCK LPTAEQLEDFTTKIQRHTLLHEDLKRFFDGFPRNAHPMPVLSSAVNALSA Mvan_5022|M.vanbaalenii_PYR-1 LPTADQLEDFTTKIQRHTLLHEDLKRFFDGFPRNAHPMPVLSSAVNALSA MSMEG_5672|M.smegmatis_MC2_155 LPTAEQLETFTNQIQRHTLLHEDLKRFFDGFPRNAHPMPVLSSAVNALSA MAB_0944|M.abscessus_ATCC_1997 LPTPQQLEDFTTKIQRHTLLHEDLKRFFDGFPRNAHPMPVLSSAANALSA TH_3084|M.thermoresistible__bu LPNTDQLAEFTTRIQRHTLLHEDLKRFFDGFPREAHPMPVLSSAVNALSA MAV_0344|M.avium_104 LPDDQQLALFSQRERAARRLNRSQLSLLHKLPDTCHPMDVVRTFISSMGA ** :** *: : : *:.. : . :* .*** *: : .::.* MMAR_4640|M.marinum_M YYQDALDPMDSEQVELSTIRLLAKLPTIAAYAYKKSVGQPFLYPENSLTL MUL_0255|M.ulcerans_Agy99 YYQDALDPMDSEQVELSTIRLLAKLPTIAAYAYKKSVGQPFLYPENSLTL Mb0920|M.bovis_AF2122/97 YYQDALDPMDNGQVELSTIRLLAKLPTIAAYAYKKSVGQPFLYPDNSLTL Rv0896|M.tuberculosis_H37Rv YYQDALDPMDNGQVELSTIRLLAKLPTIAAYAYKKSVGQPFLYPDNSLTL MLBr_02130|M.leprae_Br4923 YYQDALDPMDNGQVELSTIRLLAKLPTIAAYAYKKSVGQPFLYPDNAFSL Mflv_1729|M.gilvum_PYR-GCK YYQDSLDPFDPHQVELSTIRLLAKLPTIAAYAYKKSEGQPFLYPDNSLTL Mvan_5022|M.vanbaalenii_PYR-1 YYQDSLDPFDPKQVELSTIRLLAKLPTIAAYAYKKSEGQPFLYPDNSLTL MSMEG_5672|M.smegmatis_MC2_155 YYQDSLDPLDNKQVELSTIRLLAKLPTIAAYAYKKSEGQPFLYPDNSLSL MAB_0944|M.abscessus_ATCC_1997 YYQDSLDPHDDAQVELSTIRLLAKLPTIAAYAYKKSVGQPFLYPDNTLTL TH_3084|M.thermoresistible__bu YYPDSLDPNDTRQVELSTIRLLAKLPTIAAYAYKKSEGQPFLYPDNSLTL MAV_0344|M.avium_104 EDPDEDD-NSASANHAKALRMFAVLPTIVAADMRRRRGLEPIAPHSHMSY * * . . .::*::* ****.* :: * : *.. :: MMAR_4640|M.marinum_M VENFLRMTFGFPAEPYHPDPEVVRALDMLFILHADHEQNCSTSTVRLVGS MUL_0255|M.ulcerans_Agy99 VENFLRMTFGFPAEPYHPDPEVVRALDMLFILHADHEQNCSTSTVRLVGS Mb0920|M.bovis_AF2122/97 VENFLRLTFGFPAEPYQADPEVVRALDMLFILHADHEQNCSTSTVRLVGS Rv0896|M.tuberculosis_H37Rv VENFLRLTFGFPAEPYQADPEVVRALDMLFILHADHEQNCSTSTVRLVGS MLBr_02130|M.leprae_Br4923 VENFLRMTFGLPAEPYEPDPEVVRALDMLFILHADHEQNCSTSTVRLVGS Mflv_1729|M.gilvum_PYR-GCK VENFLRMTFGFPAEPYEVDPEIVRALDMLFILHADHEQNCSTSTVRLVGS Mvan_5022|M.vanbaalenii_PYR-1 VENFLRMTFGFPAEPYEVDPEIVRALDMLFILHADHEQNCSTSTVRLVGS MSMEG_5672|M.smegmatis_MC2_155 VENFLRMTFGFPAEPYEVDPEIVRALDMLLILHADHEQNCSTSTVRLVGS MAB_0944|M.abscessus_ATCC_1997 VENFLRMTFGLPAEPYEVDPEIVRALDMLLILHADHEQNCSTSTVRLVGS TH_3084|M.thermoresistible__bu VENFLRMTFGFPAEPYQVDPEVVRALDMLLILHADHEQNCSTSTVRLVGS MAV_0344|M.avium_104 AQNFLHMCFG-----DVPEQVIVDAFEQSMILYAEHSFNASTFAARVVTS .:***:: ** : :* *:: :**:*:*. *.** :.*:* * MMAR_4640|M.marinum_M SRANLFTSISGGINALWGPLHGGANQAVLEMLEQIRDSGDDVSEFVRKVK MUL_0255|M.ulcerans_Agy99 SRANLFTSISGGINALWGPLHGGANQAVLEMLEQIRDSGDDVSEFVRKVK Mb0920|M.bovis_AF2122/97 SRANLFTSISGGINALWGPLHGGANQAVLEMLEGIRDSGDDVSEFVRKVK Rv0896|M.tuberculosis_H37Rv SRANLFTSISGGINALWGPLHGGANQAVLEMLEGIRDSGDDVSEFVRKVK MLBr_02130|M.leprae_Br4923 SRANLFTSISGGINALWGPLHGGANQAVLEMLEGIRESGDDVGGFVQKVK Mflv_1729|M.gilvum_PYR-GCK SQANLFTSISGGINALWGPLHGGANQAVLEMLSKIRDGDDDVATFVKKVK Mvan_5022|M.vanbaalenii_PYR-1 SQANLFTSISGGINALWGPLHGGANQAVLEMLSKIRAEGGDVKEFVRKVK MSMEG_5672|M.smegmatis_MC2_155 SQANLFTSISGGINALWGPLHGGANQAVLEMLEKIRSQGGDVSDFVRKVK MAB_0944|M.abscessus_ATCC_1997 SDANLFTSVSGGINALWGPLHGGANQAVLEMLERIRSEGGDTHDFVRRVK TH_3084|M.thermoresistible__bu SQANLFTSISGGINALWGPLHGGANQAVLEMLEKIRVEGGDVRDFVRRVK MAV_0344|M.avium_104 TQSDIYSAVTAAIGALKGSLHGGANEAVMHDMLEIGTPDRAAEWLQGKLS : ::::::::..*.** *.******:**:. : * . . : ::. MMAR_4640|M.marinum_M NREAGVKLMGFGHRVYKNYDPRARIVKEQADKILSKLGGDDSLLGIAKEL MUL_0255|M.ulcerans_Agy99 NREAGVKLMGFGHRVYKNYDPRARIVKEQADKILSKLGGDDSLLGIAKEV Mb0920|M.bovis_AF2122/97 NREAGVKLMGFGHRVYKNYDPRARIVKEQADKILAKLGGDDSLLGIAKEL Rv0896|M.tuberculosis_H37Rv NREAGVKLMGFGHRVYKNYDPRARIVKEQADKILAKLGGDDSLLGIAKEL MLBr_02130|M.leprae_Br4923 NCQAGVKLMGFGHRVYKNYDPRARIVKEQADKILVKLGGDDDLLNIAKGL Mflv_1729|M.gilvum_PYR-GCK NREDNVKLMGFGHRVYKNYDPRARIVKEQADKILGKIGVHDPLLDIAKEL Mvan_5022|M.vanbaalenii_PYR-1 NREDGVKLMGFGHRVYKNYDPRARIVKEQADKILGKIGVQDDLLDIAKSL MSMEG_5672|M.smegmatis_MC2_155 NREDGVKLMGFGHRVYKNYDPRARIVKEQADKILGKLGGDDELLDIAKQL MAB_0944|M.abscessus_ATCC_1997 NREDGVKLMGFGHRVYKNYDPRARICKEQADKILGKLGGDDQLLEIAKAL TH_3084|M.thermoresistible__bu NREDNVRLMGFGHRVYKNYDPRARIVKEQADKILGKLGGDDELLNIAKEL MAV_0344|M.avium_104 RKE---KVMGFGHRVYKNGDSRVPTMKQALQRVAAVRDGQ-KWLDIYQIL . : ::********** *.*. *: ::: . . * * : : MMAR_4640|M.marinum_M EEAALTDDYFIERKLYPNVDFYTGLIYRALGFPTRMFTVLFALGRLPGWI MUL_0255|M.ulcerans_Agy99 EEAALTDDYFIERKLYPNVDFYTGLIYRALAFPTRMFTVLFALGRLPGWI Mb0920|M.bovis_AF2122/97 EEAALTDDYFIERKLYPNVDFYTGLIYRALGFPTRMFTVLFALGRLPGWI Rv0896|M.tuberculosis_H37Rv EEAALTDDYFIERKLYPNVDFYTGLIYRALGFPTRMFTVLFALGRLPGWI MLBr_02130|M.leprae_Br4923 EEAALTDDYFIERKLYPNVDFYTGLIYRALGFPTRMFTVLFALGRLPGWI Mflv_1729|M.gilvum_PYR-GCK EEIALTDDFFVERKLYPNVDYYTGVIYRAMGFPTRMFTVLFALGRLPGWI Mvan_5022|M.vanbaalenii_PYR-1 EEIALTDDFFVERKLYPNVDYYTGVIYRAMGFPTRMFTVLFALGRLPGWI MSMEG_5672|M.smegmatis_MC2_155 EEIALTDDFFIERKLYPNVDYYTGVIYRAMGFPTRMFTVLFALGRLPGWI MAB_0944|M.abscessus_ATCC_1997 EEAALTDDYFVERKLYPNVDFYTGLIYRAIGFPTRMFTVLFALGRLPGWI TH_3084|M.thermoresistible__bu EETALTDEFFIERKLYPNVDFYTGLIYRAMGFPTRMFTVLFALGRLPGWI MAV_0344|M.avium_104 ERGMARAN-----GIKPNLDFPTGPAYYLMGFDIGAFTPIFVMSRITGWT *. : : **:*: ** * :.* ** :*.:.*:.** MMAR_4640|M.marinum_M AHWREMHDEGDSKIGRPRQIYTGYTERDYVAMDGR MUL_0255|M.ulcerans_Agy99 AHWREMHDEGDSKIGRPRQIYTGYTERDYVAMDGR Mb0920|M.bovis_AF2122/97 AHWREMHDEGDSKIGRPRQIYTGYAERDYVTIDAR Rv0896|M.tuberculosis_H37Rv AHWREMHDEGDSKIGRPRQIYTGYTERDYVTIDAR MLBr_02130|M.leprae_Br4923 AHWREMHDEGDSKIGRPRQIYTGYTERDYTAIETR Mflv_1729|M.gilvum_PYR-GCK AHWREMHGE-PNKIGRPRQIYTGYTERDYAGIDTR Mvan_5022|M.vanbaalenii_PYR-1 AHWREMHGE-PNKIGRPRQIYTGYTERDYAGFDSR MSMEG_5672|M.smegmatis_MC2_155 AHWREMHSE-PNKIGRPRQIYTGYTERGYTDIAGR MAB_0944|M.abscessus_ATCC_1997 AHWREMHSE-PGKIGRPRQIYTGYGERQYP----- TH_3084|M.thermoresistible__bu AHWREMHNEGNNKIGRPRQIYTGYGERDYTPLSER MAV_0344|M.avium_104 AHIIEQTAS--NALIRPLSEYVGPPQRALS----- ** * . . : ** . *.* :*