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M. abscessus ATCC 19977 MAB_0944 (gltA)

annotation: type II citrate synthase
coordinates: 950775 - 952052
length: 425

VADNNDFATLQYPGGETKLDIVRATEGADGFALGKLLADTGYTTFDAGFVNTASTKSAITYIDGDAGILR
YRGYPIEQLADKSTFIEVSYLLIYGELPTPQQLEDFTTKIQRHTLLHEDLKRFFDGFPRNAHPMPVLSSA
ANALSAYYQDSLDPHDDAQVELSTIRLLAKLPTIAAYAYKKSVGQPFLYPDNTLTLVENFLRMTFGLPAE
PYEVDPEIVRALDMLLILHADHEQNCSTSTVRLVGSSDANLFTSVSGGINALWGPLHGGANQAVLEMLER
IRSEGGDTHDFVRRVKNREDGVKLMGFGHRVYKNYDPRARICKEQADKILGKLGGDDQLLEIAKALEEAA
LTDDYFVERKLYPNVDFYTGLIYRAIGFPTRMFTVLFALGRLPGWIAHWREMHSEPGKIGRPRQIYTGYG
ERQYP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_0944gltA-100% (425)type II citrate synthase
M. abscessus ATCC 19977MAB_4619-3e-5033.95% (380) citrate synthase
M. abscessus ATCC 19977MAB_0932c-2e-3632.23% (394) citrate synthase 2

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0920gltA0.084.71% (425) type II citrate synthase
M. gilvum PYR-GCKMflv_1729gltA0.086.45% (428) type II citrate synthase
M. tuberculosis H37RvRv0896gltA0.084.71% (425) type II citrate synthase
M. leprae Br4923MLBr_02130gltA0.083.76% (425) type II citrate synthase
M. marinum MMMAR_4640gltA0.084.47% (425) citrate synthase I GltA2
M. avium 104MAV_0344-1e-4532.00% (375) methylcitrate synthase
M. smegmatis MC2 155MSMEG_5672gltA0.087.94% (423) type II citrate synthase
M. thermoresistible (build 8)TH_3084-0.087.08% (418) PUTATIVE citrate synthase I
M. ulcerans Agy99MUL_0255gltA0.083.76% (425) type II citrate synthase
M. vanbaalenii PYR-1Mvan_5022gltA0.087.62% (428) type II citrate synthase

CLUSTAL 2.0.9 multiple sequence alignment


Mb0920|M.bovis_AF2122/97            MADT----DDTATLRYPGGEIDLQIVHATEGADGIALGPLLAKTGHTTFD
Rv0896|M.tuberculosis_H37Rv         MADT----DDTATLRYPGGEIDLQIVHATEGADGIALGPLLAKTGHTTFD
MMAR_4640|M.marinum_M               MSDT----DDTATLKYPGGEIDLQIAHATEGADGIALGPLLSKTGHTTFD
MUL_0255|M.ulcerans_Agy99           MSDT----DDTATLKYPGGEIDLQIAHATEGADGIALGPLLSKTGHTTFD
MLBr_02130|M.leprae_Br4923          MADT----DDTVTLKYPGGEIDLQIVRATEGNDGIAIVPVLAKTGYTTFD
Mflv_1729|M.gilvum_PYR-GCK          MADNAEAGQEHATLSYPGGELELDIVKASEGSDGIALGSLLAKTGYTTFD
Mvan_5022|M.vanbaalenii_PYR-1       MADNADAGQEHATLVYPGGELELDIVKASEGADGIALGSLLAKSGYTTFD
MSMEG_5672|M.smegmatis_MC2_155      MAEKPSNGQEHATVKYPGGELDLEIVHATEGADGIALGSLLAKTGYTTYD
MAB_0944|M.abscessus_ATCC_1997      MADN----NDFATLQYPGGETKLDIVRATEGADGFALGKLLADTGYTTFD
TH_3084|M.thermoresistible__bu      VAENASSGDKHATLIYPGGQIDLEIVRATEGADGIALGSMLAETGYTTFD
MAV_0344|M.avium_104                --------------------------------------MSTLEDNQPRIH
                                                                              . . .  .

Mb0920|M.bovis_AF2122/97            VGFANTAAAKSSITYIDGDAGILRYRGYPIDQLAEKSTFIEVCYLLIYGE
Rv0896|M.tuberculosis_H37Rv         VGFANTAAAKSSITYIDGDAGILRYRGYPIDQLAEKSTFIEVCYLLIYGE
MMAR_4640|M.marinum_M               NGFVNTASCKSSITYIDGDAGILRYRGYPIDQLAEKSTFIEVCYLLIYGE
MUL_0255|M.ulcerans_Agy99           NGFANTASCKSSITYIDGDAGILRYRGYPIDQLAEKSTFIEVCYLLIYGE
MLBr_02130|M.leprae_Br4923          VGYGNTASTKSSITYIDGDAGILRYRGYPIEQLAEKSTFIEVCYLLIYGE
Mflv_1729|M.gilvum_PYR-GCK          GGFVNTASTKSAITYIDGDAGILRYRGYPIEQLAEKSTFIEVSYLLIYGE
Mvan_5022|M.vanbaalenii_PYR-1       GGFVNTASTKSAITYIDGDAGILRYRGYPIEQLAEKSNFIEVSYLLIYGE
MSMEG_5672|M.smegmatis_MC2_155      GGFVNTASTKSAITYIDGDAGILRYRGYPIEQLAEKSTFIEVSYLLIYGE
MAB_0944|M.abscessus_ATCC_1997      AGFVNTASTKSAITYIDGDAGILRYRGYPIEQLADKSTFIEVSYLLIYGE
TH_3084|M.thermoresistible__bu      SGFVNTASTKSSITYIDGEAGILRYRGYPIEQLAEKSTFIEVCFLLIYGE
MAV_0344|M.avium_104                KGLAGVVVDTTAISKVVPETNSLTYRGYAVQDLAAHCSFEQVAYLLWYGE
                                     *  ...  .::*: :  ::. * ****.:::** :..* :*.:** ***

Mb0920|M.bovis_AF2122/97            LPDTDQLAQFTGRIQRHTMLHEDLKRFFDGFPRNAHPMPVLSSVVNALSA
Rv0896|M.tuberculosis_H37Rv         LPDTDQLAQFTGRIQRHTMLHEDLKRFFDGFPRNAHPMPVLSSVVNALSA
MMAR_4640|M.marinum_M               LPNTDQLAQFTGRIQRHTMLHEDLKRFFDGFPRNAHPMPVLSSVVNALSA
MUL_0255|M.ulcerans_Agy99           LPNTDQLAQFTGRIQRHTMLHEDLKRFFDGFPRNAHPMPVLSSVVNALSA
MLBr_02130|M.leprae_Br4923          LPATDQLAEFTHRIQRHTMLHEDLKRFYDGFPRNAHPMPVLSSVVNALSA
Mflv_1729|M.gilvum_PYR-GCK          LPTAEQLEDFTTKIQRHTLLHEDLKRFFDGFPRNAHPMPVLSSAVNALSA
Mvan_5022|M.vanbaalenii_PYR-1       LPTADQLEDFTTKIQRHTLLHEDLKRFFDGFPRNAHPMPVLSSAVNALSA
MSMEG_5672|M.smegmatis_MC2_155      LPTAEQLETFTNQIQRHTLLHEDLKRFFDGFPRNAHPMPVLSSAVNALSA
MAB_0944|M.abscessus_ATCC_1997      LPTPQQLEDFTTKIQRHTLLHEDLKRFFDGFPRNAHPMPVLSSAANALSA
TH_3084|M.thermoresistible__bu      LPNTDQLAEFTTRIQRHTLLHEDLKRFFDGFPREAHPMPVLSSAVNALSA
MAV_0344|M.avium_104                LPDDQQLALFSQRERAARRLNRSQLSLLHKLPDTCHPMDVVRTFISSMGA
                                    **  :**  *: : :    *:..   : . :*  .*** *: :  .::.*

Mb0920|M.bovis_AF2122/97            YYQDALDPMDNGQVELSTIRLLAKLPTIAAYAYKKSVGQPFLYPDNSLTL
Rv0896|M.tuberculosis_H37Rv         YYQDALDPMDNGQVELSTIRLLAKLPTIAAYAYKKSVGQPFLYPDNSLTL
MMAR_4640|M.marinum_M               YYQDALDPMDSEQVELSTIRLLAKLPTIAAYAYKKSVGQPFLYPENSLTL
MUL_0255|M.ulcerans_Agy99           YYQDALDPMDSEQVELSTIRLLAKLPTIAAYAYKKSVGQPFLYPENSLTL
MLBr_02130|M.leprae_Br4923          YYQDALDPMDNGQVELSTIRLLAKLPTIAAYAYKKSVGQPFLYPDNAFSL
Mflv_1729|M.gilvum_PYR-GCK          YYQDSLDPFDPHQVELSTIRLLAKLPTIAAYAYKKSEGQPFLYPDNSLTL
Mvan_5022|M.vanbaalenii_PYR-1       YYQDSLDPFDPKQVELSTIRLLAKLPTIAAYAYKKSEGQPFLYPDNSLTL
MSMEG_5672|M.smegmatis_MC2_155      YYQDSLDPLDNKQVELSTIRLLAKLPTIAAYAYKKSEGQPFLYPDNSLSL
MAB_0944|M.abscessus_ATCC_1997      YYQDSLDPHDDAQVELSTIRLLAKLPTIAAYAYKKSVGQPFLYPDNTLTL
TH_3084|M.thermoresistible__bu      YYPDSLDPNDTRQVELSTIRLLAKLPTIAAYAYKKSEGQPFLYPDNSLTL
MAV_0344|M.avium_104                EDPDEDD-NSASANHAKALRMFAVLPTIVAADMRRRRGLEPIAPHSHMSY
                                       *  *  .    . .::*::* ****.*   ::  *   : *.. :: 

Mb0920|M.bovis_AF2122/97            VENFLRLTFGFPAEPYQADPEVVRALDMLFILHADHEQNCSTSTVRLVGS
Rv0896|M.tuberculosis_H37Rv         VENFLRLTFGFPAEPYQADPEVVRALDMLFILHADHEQNCSTSTVRLVGS
MMAR_4640|M.marinum_M               VENFLRMTFGFPAEPYHPDPEVVRALDMLFILHADHEQNCSTSTVRLVGS
MUL_0255|M.ulcerans_Agy99           VENFLRMTFGFPAEPYHPDPEVVRALDMLFILHADHEQNCSTSTVRLVGS
MLBr_02130|M.leprae_Br4923          VENFLRMTFGLPAEPYEPDPEVVRALDMLFILHADHEQNCSTSTVRLVGS
Mflv_1729|M.gilvum_PYR-GCK          VENFLRMTFGFPAEPYEVDPEIVRALDMLFILHADHEQNCSTSTVRLVGS
Mvan_5022|M.vanbaalenii_PYR-1       VENFLRMTFGFPAEPYEVDPEIVRALDMLFILHADHEQNCSTSTVRLVGS
MSMEG_5672|M.smegmatis_MC2_155      VENFLRMTFGFPAEPYEVDPEIVRALDMLLILHADHEQNCSTSTVRLVGS
MAB_0944|M.abscessus_ATCC_1997      VENFLRMTFGLPAEPYEVDPEIVRALDMLLILHADHEQNCSTSTVRLVGS
TH_3084|M.thermoresistible__bu      VENFLRMTFGFPAEPYQVDPEVVRALDMLLILHADHEQNCSTSTVRLVGS
MAV_0344|M.avium_104                AQNFLHMCFG-----DVPEQVIVDAFEQSMILYAEHSFNASTFAARVVTS
                                    .:***:: **        :  :* *::  :**:*:*. *.** :.*:* *

Mb0920|M.bovis_AF2122/97            SRANLFTSISGGINALWGPLHGGANQAVLEMLEGIRDSGDDVSEFVRKVK
Rv0896|M.tuberculosis_H37Rv         SRANLFTSISGGINALWGPLHGGANQAVLEMLEGIRDSGDDVSEFVRKVK
MMAR_4640|M.marinum_M               SRANLFTSISGGINALWGPLHGGANQAVLEMLEQIRDSGDDVSEFVRKVK
MUL_0255|M.ulcerans_Agy99           SRANLFTSISGGINALWGPLHGGANQAVLEMLEQIRDSGDDVSEFVRKVK
MLBr_02130|M.leprae_Br4923          SRANLFTSISGGINALWGPLHGGANQAVLEMLEGIRESGDDVGGFVQKVK
Mflv_1729|M.gilvum_PYR-GCK          SQANLFTSISGGINALWGPLHGGANQAVLEMLSKIRDGDDDVATFVKKVK
Mvan_5022|M.vanbaalenii_PYR-1       SQANLFTSISGGINALWGPLHGGANQAVLEMLSKIRAEGGDVKEFVRKVK
MSMEG_5672|M.smegmatis_MC2_155      SQANLFTSISGGINALWGPLHGGANQAVLEMLEKIRSQGGDVSDFVRKVK
MAB_0944|M.abscessus_ATCC_1997      SDANLFTSVSGGINALWGPLHGGANQAVLEMLERIRSEGGDTHDFVRRVK
TH_3084|M.thermoresistible__bu      SQANLFTSISGGINALWGPLHGGANQAVLEMLEKIRVEGGDVRDFVRRVK
MAV_0344|M.avium_104                TQSDIYSAVTAAIGALKGSLHGGANEAVMHDMLEIGTPDRAAEWLQGKLS
                                    : ::::::::..*.** *.******:**:. :  *   .  .  :  ::.

Mb0920|M.bovis_AF2122/97            NREAGVKLMGFGHRVYKNYDPRARIVKEQADKILAKLGGDDSLLGIAKEL
Rv0896|M.tuberculosis_H37Rv         NREAGVKLMGFGHRVYKNYDPRARIVKEQADKILAKLGGDDSLLGIAKEL
MMAR_4640|M.marinum_M               NREAGVKLMGFGHRVYKNYDPRARIVKEQADKILSKLGGDDSLLGIAKEL
MUL_0255|M.ulcerans_Agy99           NREAGVKLMGFGHRVYKNYDPRARIVKEQADKILSKLGGDDSLLGIAKEV
MLBr_02130|M.leprae_Br4923          NCQAGVKLMGFGHRVYKNYDPRARIVKEQADKILVKLGGDDDLLNIAKGL
Mflv_1729|M.gilvum_PYR-GCK          NREDNVKLMGFGHRVYKNYDPRARIVKEQADKILGKIGVHDPLLDIAKEL
Mvan_5022|M.vanbaalenii_PYR-1       NREDGVKLMGFGHRVYKNYDPRARIVKEQADKILGKIGVQDDLLDIAKSL
MSMEG_5672|M.smegmatis_MC2_155      NREDGVKLMGFGHRVYKNYDPRARIVKEQADKILGKLGGDDELLDIAKQL
MAB_0944|M.abscessus_ATCC_1997      NREDGVKLMGFGHRVYKNYDPRARICKEQADKILGKLGGDDQLLEIAKAL
TH_3084|M.thermoresistible__bu      NREDNVRLMGFGHRVYKNYDPRARIVKEQADKILGKLGGDDELLNIAKEL
MAV_0344|M.avium_104                RKE---KVMGFGHRVYKNGDSRVPTMKQALQRVAAVRDGQ-KWLDIYQIL
                                    . :   ::********** *.*.   *:  :::    . .   * * : :

Mb0920|M.bovis_AF2122/97            EEAALTDDYFIERKLYPNVDFYTGLIYRALGFPTRMFTVLFALGRLPGWI
Rv0896|M.tuberculosis_H37Rv         EEAALTDDYFIERKLYPNVDFYTGLIYRALGFPTRMFTVLFALGRLPGWI
MMAR_4640|M.marinum_M               EEAALTDDYFIERKLYPNVDFYTGLIYRALGFPTRMFTVLFALGRLPGWI
MUL_0255|M.ulcerans_Agy99           EEAALTDDYFIERKLYPNVDFYTGLIYRALAFPTRMFTVLFALGRLPGWI
MLBr_02130|M.leprae_Br4923          EEAALTDDYFIERKLYPNVDFYTGLIYRALGFPTRMFTVLFALGRLPGWI
Mflv_1729|M.gilvum_PYR-GCK          EEIALTDDFFVERKLYPNVDYYTGVIYRAMGFPTRMFTVLFALGRLPGWI
Mvan_5022|M.vanbaalenii_PYR-1       EEIALTDDFFVERKLYPNVDYYTGVIYRAMGFPTRMFTVLFALGRLPGWI
MSMEG_5672|M.smegmatis_MC2_155      EEIALTDDFFIERKLYPNVDYYTGVIYRAMGFPTRMFTVLFALGRLPGWI
MAB_0944|M.abscessus_ATCC_1997      EEAALTDDYFVERKLYPNVDFYTGLIYRAIGFPTRMFTVLFALGRLPGWI
TH_3084|M.thermoresistible__bu      EETALTDEFFIERKLYPNVDFYTGLIYRAMGFPTRMFTVLFALGRLPGWI
MAV_0344|M.avium_104                ERGMARAN-----GIKPNLDFPTGPAYYLMGFDIGAFTPIFVMSRITGWT
                                    *.     :      : **:*: **  *  :.*    ** :*.:.*:.** 

Mb0920|M.bovis_AF2122/97            AHWREMHDEGDSKIGRPRQIYTGYAERDYVTIDAR
Rv0896|M.tuberculosis_H37Rv         AHWREMHDEGDSKIGRPRQIYTGYTERDYVTIDAR
MMAR_4640|M.marinum_M               AHWREMHDEGDSKIGRPRQIYTGYTERDYVAMDGR
MUL_0255|M.ulcerans_Agy99           AHWREMHDEGDSKIGRPRQIYTGYTERDYVAMDGR
MLBr_02130|M.leprae_Br4923          AHWREMHDEGDSKIGRPRQIYTGYTERDYTAIETR
Mflv_1729|M.gilvum_PYR-GCK          AHWREMHGE-PNKIGRPRQIYTGYTERDYAGIDTR
Mvan_5022|M.vanbaalenii_PYR-1       AHWREMHGE-PNKIGRPRQIYTGYTERDYAGFDSR
MSMEG_5672|M.smegmatis_MC2_155      AHWREMHSE-PNKIGRPRQIYTGYTERGYTDIAGR
MAB_0944|M.abscessus_ATCC_1997      AHWREMHSE-PGKIGRPRQIYTGYGERQYP-----
TH_3084|M.thermoresistible__bu      AHWREMHNEGNNKIGRPRQIYTGYGERDYTPLSER
MAV_0344|M.avium_104                AHIIEQTAS--NALIRPLSEYVGPPQRALS-----
                                    **  *   .  . : ** . *.*  :*