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MSYVMAVPELLASAAADLEGIGSALSTANALALPSTSEILAAGTDEISTAVASLFADHAQDYRTISLEAN AFHQQFWRSLSGAAASYSGAEAANASPLQELLNVINQQSTALLGRPLIGNGADGAAPGQSGDDGGLLFGN GGNGAPGTNQGVAGGNGGSAGLIGNGGAGGLGGPGGAGGAGGHGGMLFGDGGAGGGGGDSPSFVIGGGAG GNGGNAGLFGNAGAGGAGGAGQQFFFNGGAGGDGGSVGLIGNGGAGGDGANGAAGGAGGDGGMLSGNGGN GGAGGDLNDPAVPTGSQVGGRGGNAGLIGNGGIGGDGGVAANGGAGGQGGLLRGDGGDGGAGGAGRPASF NSNGGPGGNGGNGGSAGLWGNGGTGGAGGGPGTQGSDNSGSGGNGGNGGNAGLFSGIAGNGGDGGQGGEA DRTGGVGGMGGAGGAAGLFGTGGTGGTGGTGGAANPFGAAGGSGGSGGAGGAGGLLRGMGGAGGTGGTGG AASGGSPAGAGGTGGTGGAAGLIGVGGSGGAGGDGLLFSDAGVGGSGGTGGAGGWFYGTGGGGGAGGVSA TTGNGGNGGNAGLIGDGGAGGAGAIPGAGGAGGRIFGALGLPG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4571 | - | - | 100% (603) | PE-PGRS family protein |
| M. marinum M | MMAR_1208 | - | e-171 | 53.00% (634) | PE-PGRS family protein |
| M. marinum M | MMAR_3316 | - | e-169 | 51.53% (687) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1121 | PE_PGRS22 | 1e-166 | 47.14% (751) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-112 | 44.24% (608) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1091 | PE_PGRS22 | 1e-162 | 45.76% (754) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 1e-10 | 32.29% (96) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 8e-50 | 31.70% (552) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 7e-25 | 43.11% (167) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 5e-97 | 39.63% (656) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 4e-43 | 41.52% (289) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4431 | - | 0.0 | 94.86% (603) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-116 | 48.07% (545) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4571|M.marinum_M --------------------------------------------------
MUL_4431|M.ulcerans_Agy99 --------------------------------------------------
Mb1121|M.bovis_AF2122/97 --------------------------------------------------
Rv1091|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_4571|M.marinum_M --------------------------------------------------
MUL_4431|M.ulcerans_Agy99 --------------------------------------------------
Mb1121|M.bovis_AF2122/97 --------------------------------------------------
Rv1091|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_4571|M.marinum_M ------------------------------------------MSYVMAVP
MUL_4431|M.ulcerans_Agy99 ------------------------------------------MSYVMAVP
Mb1121|M.bovis_AF2122/97 ------------------------------------------MSFVIAAP
Rv1091|M.tuberculosis_H37Rv ------------------------------------------MSFVIAAP
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_4571|M.marinum_M ----------------------------------------ELLASAAADL
MUL_4431|M.ulcerans_Agy99 ----------------------------------------ELLASAAADL
Mb1121|M.bovis_AF2122/97 ----------------------------------------EALVAVASDL
Rv1091|M.tuberculosis_H37Rv ----------------------------------------EALVAVASDL
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------VEAASYVADP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_4571|M.marinum_M EG----------------------IGSALS-----------TANALALPS
MUL_4431|M.ulcerans_Agy99 EG----------------------IGSALS-----------TANALALPS
Mb1121|M.bovis_AF2122/97 AG----------------------IGSALA-----------EANAAALAP
Rv1091|M.tuberculosis_H37Rv AG----------------------IGSALA-----------EANAAALAP
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 EA----------------------ALANAG------------LSAVSAAQ
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------------------------------------------MNIVLGVS
MMAR_4571|M.marinum_M TS-------EILAAGTDEISTAVASLFADHAQDYRTISLEANAFHQQFWR
MUL_4431|M.ulcerans_Agy99 TS-------EILAAGTDEISTAVASLFADHAQDYRTISLEANAFHQQFWR
Mb1121|M.bovis_AF2122/97 TT-------ALLAAGADEVSAAIAALFGAHGQAYQTVSAQASAFHAQFVQ
Rv1091|M.tuberculosis_H37Rv TT-------ALLAAGADEVSAAIAALFGAHGQAYQTVSAQASAFHAQFVQ
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
MAB_4284c|M.abscessus_ATCC_199 VG-------AVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQ
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 MAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGT
MMAR_4571|M.marinum_M SLSGAAASYSGAEAANASPLQ----ELLNVINQQSTALLGRPLIGNGADG
MUL_4431|M.ulcerans_Agy99 SLSGAAASYSGAEAANASPLQ----ELLNVINQQSTALLGRPLIGNGADG
Mb1121|M.bovis_AF2122/97 ALTGGGGAYAAAEAANVSAAQSTDQRLLDLINGPTQALLGRPLIGDGANG
Rv1091|M.tuberculosis_H37Rv ALTGGGGAYAAAEAANVSAAQSTDQRLLDLINGPTQALLGRPLIGDGANG
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSR--------------------------GGDGGDG
MAB_4284c|M.abscessus_ATCC_199 PDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 REGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAA
MMAR_4571|M.marinum_M AAPGQSGDDGGLLFGNGGNGAPGTNQGVAGGNGGSAG------------L
MUL_4431|M.ulcerans_Agy99 AAPGQSGDDGGLLFGNGGNGAPGTNQGVAGGNGGSAG------------L
Mb1121|M.bovis_AF2122/97 G-PGQDGGPGGLLYGNGGNGGTSTTAGVAGGNGGAAG------------L
Rv1091|M.tuberculosis_H37Rv G-PGQDGGPGGLLYGNGGNGGTSTTAGVAGGNGGAAG------------L
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAG--AAGAAGAAG-------------
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAG--AAGAAGKAG-------------
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAG--AAGNGGDGGNGGFGYVLIAGPN
TH_3810|M.thermoresistible__bu GLGGNGGHGGG-------TGIISLLS--LAGNGGNGG-------------
MAB_4284c|M.abscessus_ATCC_199 RGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGPIAS-----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 LAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIP-------------
MMAR_4571|M.marinum_M IGNGGAGGLGGPGGAGGAGGHGGMLFGDGGAGGGGGDS------------
MUL_4431|M.ulcerans_Agy99 IGNGGAG------------GHGGMLFGDGGAGGGGGDS------------
Mb1121|M.bovis_AF2122/97 IGNGGAGGGGGAGAAGGNGGAGGWLYGNGGAGGAGGTSVI----------
Rv1091|M.tuberculosis_H37Rv IGNGGAGGGGGAGAAGGNGGAGGWLYGNGGAGGAGGTSVI----------
Mflv_5091|M.gilvum_PYR-GCK -AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG--------------
Mvan_1264|M.vanbaalenii_PYR-1 -AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG--------------
MSMEG_0868|M.smegmatis_MC2_155 VTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVD
TH_3810|M.thermoresistible__bu ---------------------NGYRTTDNNALDGGH--------------
MAB_4284c|M.abscessus_ATCC_199 -GQGSTAVNGDVRDSNIINADHGSNVGVDQSQTRVGGDYTN---------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --DVYKQQIRAESYGDAAGQLSAMVAGLEKLESLPGG-------------
MMAR_4571|M.marinum_M PSFVIG-------------GGAGGNGGN----------------------
MUL_4431|M.ulcerans_Agy99 PSFVIG-------------GGAGGNGGN----------------------
Mb1121|M.bovis_AF2122/97 PGVAGGNGGAGGSAGLWGTGGAGGDGGNGR-----SGPVNVAGSAGGNGG
Rv1091|M.tuberculosis_H37Rv PGVAGGNGGAGGSAGLWGTGGAGGDGGNGR-----SGPVNVAGSAGGNGG
Mflv_5091|M.gilvum_PYR-GCK --AVGAAGAAG------TVGTAGATGGTG---------------TGANGG
Mvan_1264|M.vanbaalenii_PYR-1 --AIGTAGVAG------AAGTAGATGGTG---------------VGGNGG
MSMEG_0868|M.smegmatis_MC2_155 GHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGG
TH_3810|M.thermoresistible__bu -------------------GGNGGN-------------------------
MAB_4284c|M.abscessus_ATCC_199 ---VSGHGSADIDKSVTVVDDHSQRNTTNIN-------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----------------LLLVGSGVDVAPLK-------------------Q
MMAR_4571|M.marinum_M ----AGLFGNAGAG-------------------GAGG----AGQQFFFN-
MUL_4431|M.ulcerans_Agy99 ----AGLFGNAGAG-------------------GAGG----AGQQFFFN-
Mb1121|M.bovis_AF2122/97 AGGAAGLFGDAGAG-------------------GNGGKGGAGGAAFSINF
Rv1091|M.tuberculosis_H37Rv AGGAAGLFGDAGAG-------------------GNGGKGGAGGAAFSINF
Mflv_5091|M.gilvum_PYR-GCK AGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGG
Mvan_1264|M.vanbaalenii_PYR-1 AGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGG
MSMEG_0868|M.smegmatis_MC2_155 HSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGE
TH_3810|M.thermoresistible__bu ----VGFFSLFNLG------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----DSFNTDRSTN--------------------IGSGNTTNTEIGSHNQ
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 VLQTTTFLDVSVAE-------------------EPETALARGAALAAANA
MMAR_4571|M.marinum_M ---------GGAGGDGGSVGLIGNGGAGGDG-------------------
MUL_4431|M.ulcerans_Agy99 ---------GGAGGDGGSVGLIGNGGAGGDG-------------------
Mb1121|M.bovis_AF2122/97 T--AGDGGAGGAGGSGGHALLWGAGGAGGNGGSGGTGGAGG---------
Rv1091|M.tuberculosis_H37Rv T--AGDGGAGGAGGSGGHALLWGAGGAGGNGGSGGTGGAGG---------
Mflv_5091|M.gilvum_PYR-GCK Q--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG---------
Mvan_1264|M.vanbaalenii_PYR-1 Q--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG---------
MSMEG_0868|M.smegmatis_MC2_155 IYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASG
TH_3810|M.thermoresistible__bu ----------GAGGWGGSG-VDGVDVVGGNP-------------------
MAB_4284c|M.abscessus_ATCC_199 ANIGTSTSAGGSAAVGGNAGLAGNAGLAGNAG------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PLFASSTAALAYAQDPGTGAVDQYSLPDYLYVP-----------------
MMAR_4571|M.marinum_M ----------ANGAAGGAGGDGGMLSG---------------------NG
MUL_4431|M.ulcerans_Agy99 ----------ANGAAGGAGGDGGMLSG---------------------NG
Mb1121|M.bovis_AF2122/97 ----STAGAGGNGGAGGGGGTGGLLFG---------------------NG
Rv1091|M.tuberculosis_H37Rv ----STAGAGGNGGAGGGGGTGGLLFG---------------------NG
Mflv_5091|M.gilvum_PYR-GCK ----LQGGKGGDGGAGGKGGDADSMGS------------------AGATG
Mvan_1264|M.vanbaalenii_PYR-1 ----LQGGQGGDGGTGGTGGDATSMGE------------------AGATG
MSMEG_0868|M.smegmatis_MC2_155 TAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANG
TH_3810|M.thermoresistible__bu ------------------------------------------------DG
MAB_4284c|M.abscessus_ATCC_199 -----------LAGNAGLAGNAGLAGN----------------------A
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------VDPEPGDDELAYS--------------------AVG
MMAR_4571|M.marinum_M GNGGAGGDLNDPAVP----------------------TG-----------
MUL_4431|M.ulcerans_Agy99 GNGGAGGDLNDPAVP----------------------TG-----------
Mb1121|M.bovis_AF2122/97 GAGGHGAAAGNGLAAGNGVSSSG--------GGGAGGTGGAG--------
Rv1091|M.tuberculosis_H37Rv GAGGHGAAAGNGLAAGNGVSSSG--------GGGAGGTGGAG--------
Mflv_5091|M.gilvum_PYR-GCK GKGGNGGNGGRGGLFG---------------KGGNAGNGAD---------
Mvan_1264|M.vanbaalenii_PYR-1 GKGGNGGNGGRGSLFG---------------RGGNAGNGGN---------
MSMEG_0868|M.smegmatis_MC2_155 AVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPN
TH_3810|M.thermoresistible__bu GTPGAHGESHTPGVYT----------------------------------
MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAGLAG----------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 EEDAESPTVVIEKLFLP---------------------------------
MMAR_4571|M.marinum_M ----------SQVGGRGGNAGLIGNGG-IGGDGGVAA-------------
MUL_4431|M.ulcerans_Agy99 ----------SQVGGRGGNAGLIGNGG-IGGDGGVAA-------------
Mb1121|M.bovis_AF2122/97 --------GDGGAGGAGGNARLWGVGG-AGGAGGDGG-------------
Rv1091|M.tuberculosis_H37Rv --------GDGGAGGAGGNARLWGVGG-AGGAGGDGG-------------
Mflv_5091|M.gilvum_PYR-GCK -------------GGTGGAGGAGGTGG-TGGAGGTGG-------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------GGTGGNGGNGGTGG-TGGNGGTGG-------------
MSMEG_0868|M.smegmatis_MC2_155 GPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHST
TH_3810|M.thermoresistible__bu --------------DRQGEDGEDGTGTGIGGRGGNGG-------------
MAB_4284c|M.abscessus_ATCC_199 ------------NAGLAGNAGLAGNAGLAGNAGLAGN-------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----------EDSEPRRRPVLLVGSGLAVVGISAVLALEIALAIG-----
MMAR_4571|M.marinum_M ----NGGAGGQGG-------------------------------LLRGDG
MUL_4431|M.ulcerans_Agy99 ----NGGAGGQGG-------------------------------LLRGDG
Mb1121|M.bovis_AF2122/97 ----AGGAGGKGGSGLSGNANGGAGGDSGRGGTGGAGGEGGAAGLLVGTG
Rv1091|M.tuberculosis_H37Rv ----AGGAGGKGGSGLSGNANGGAGGDSGRGGTGGAGGEGGAAGLLVGTG
Mflv_5091|M.gilvum_PYR-GCK ----TGGTGGIGGAG-------STGGTGGTGGTGGTGGTGGTG-GTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 ----TGGTGGIGGAG-------STGGTGGTGGTGGTGGTGGTG-GTGGTG
MSMEG_0868|M.smegmatis_MC2_155 GQTDTGGNGGRGGDG-------GTFVNAGANGNGGAGGAGGVSEGEGGTG
TH_3810|M.thermoresistible__bu -----SSSGTHP----------------------------------MAED
MAB_4284c|M.abscessus_ATCC_199 ----AGLAGNAG---------------------------------LAGNA
MLBr_01183|M.leprae_Br4923 ---------------------------------------------MPLFL
MAV_4827|M.avium_104 ----IRTTGTVALQP------------------------------TPNQH
MMAR_4571|M.marinum_M GDGGAGGAGRPASFNSNG---------GPGGNGGNGGSAG----------
MUL_4431|M.ulcerans_Agy99 GDGGAGGAGRPASFNSNG---------GPGGNGGNGGSAG----------
Mb1121|M.bovis_AF2122/97 GHGGDGGAGGAAVKGGDGGAAAGTGIAGAGGRGGAGGSGGSGGDGGGGAA
Rv1091|M.tuberculosis_H37Rv GHGGDGGAGGAAVKGGDGGAAAGTGIAGAGGRGGAGGSGGSGGDGGGGAA
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGKGGTGGTGGAGGTG------GDGGTGGTGGTGGTG--------
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGKGGTGGTGGDGGTG------GTGGTGGTGGTGGTG--------
MSMEG_0868|M.smegmatis_MC2_155 GHGGDGGRGGDGALGGNGGTGGVG--LGNGGKGGNGGNGGNGGTYVDPSH
TH_3810|M.thermoresistible__bu GEHVKALDGRPGLDGGNG---------SHGGNGGHGGRGG----------
MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGN---------
MLBr_01183|M.leprae_Br4923 NAEPQALTAAANTLEGLS----------AATVASNAAAAQ----------
MAV_4827|M.avium_104 LIVPTEQAPAPPPVQASAPQPKISVPEPVAAPKPLSPPVAAP--------
. . . .
MMAR_4571|M.marinum_M -----LWGNGGTGG-----------AGGGPGTQGS------DNSGSGGNG
MUL_4431|M.ulcerans_Agy99 -----LWGNGGTGG-----------AGGGPGTQGS------DNSGSGGNG
Mb1121|M.bovis_AF2122/97 GPAGWLFGDGGAGGN------GGAAAAGGAGGQAG------GGGGNGGNG
Rv1091|M.tuberculosis_H37Rv GPAGWLFGDGGAGGN------GGAAAAGGAGGQAG------GGGGNGGNG
Mflv_5091|M.gilvum_PYR-GCK -GTGGTGGTGGAG-----------DGTGGTGGTGG----TGGQGGQGGQG
Mvan_1264|M.vanbaalenii_PYR-1 -GTGGTGGTGGAG-----------DGLGGTGGTGG----TGGFGGQGGQG
MSMEG_0868|M.smegmatis_MC2_155 TGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDG
TH_3810|M.thermoresistible__bu -----FLGIGGSG------------GWGGHGGNGG------DTDADGGNG
MAB_4284c|M.abscessus_ATCC_199 ---AAVAGNAAVAGN---------AAVAGNAAVGG----VLNTGVSGAIG
MLBr_01183|M.leprae_Br4923 -----LTTEIAPP------------AADDVSILLA--------HFFSGHG
MAV_4827|M.avium_104 -----LPAAPPPAAP---------PLPEAPPIPAAPPVVPVPVVVPPVPV
.
MMAR_4571|M.marinum_M G-----------------NGGNAG--------LFSG--------------
MUL_4431|M.ulcerans_Agy99 G-----------------NGGNAG--------LFSG--------------
Mb1121|M.bovis_AF2122/97 G-----------------NGGNGGNGG----NGATGG-------------
Rv1091|M.tuberculosis_H37Rv G-----------------NGGNGGNGG----NGATGG-------------
Mflv_5091|M.gilvum_PYR-GCK G-----------------TGGTGGQGG-LGGGGGTG--------------
Mvan_1264|M.vanbaalenii_PYR-1 G-----------------TGGTGGQGG-LGGVGGTG--------------
MSMEG_0868|M.smegmatis_MC2_155 GEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQAN
TH_3810|M.thermoresistible__bu G-------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 G-----------------SSHVGGAIN-----------------------
MLBr_01183|M.leprae_Br4923 R-------------------------------------------------
MAV_4827|M.avium_104 P-------------------------------------------------
MMAR_4571|M.marinum_M ----------IAGNGGDGGQGGEADR---------------------TGG
MUL_4431|M.ulcerans_Agy99 ----------IAGNGGDGGQGGEADR---------------------TGG
Mb1121|M.bovis_AF2122/97 ---------WLYGNGGAGGQGATAGAGGAGANGVSSTNGG---GNGGIGG
Rv1091|M.tuberculosis_H37Rv ---------WLYGNGGAGGQGATAGAGGAGANGVSSTNGGGTGGNGGIGG
Mflv_5091|M.gilvum_PYR-GCK ---------GQGGTGGTGGQGGTGGTGGTGGTG----------------G
Mvan_1264|M.vanbaalenii_PYR-1 ---------GTGGTGGTGGQGGTGGTGGTGGTG----------------G
MSMEG_0868|M.smegmatis_MC2_155 PQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASG--------IG
TH_3810|M.thermoresistible__bu ----------DGGNGGSAGRGGTGGLR----------------------G
MAB_4284c|M.abscessus_ATCC_199 --------ESLGGSGSVGGSTAVGGGAHTGVGGGVSTG----------VG
MLBr_01183|M.leprae_Br4923 ---------------QYQAHASQG--------------------------
MAV_4827|M.avium_104 ----------VPVRIPVPDPVSPPQLLAPPRLSVP-------------QP
.
MMAR_4571|M.marinum_M VGGMGGAGGAAGLFGTGGTGGTGGTGGAANPFGAAG--------------
MUL_4431|M.ulcerans_Agy99 VGGMGGAGGAAGLFGTGGTRGTGGTGGAANPFGAAG--------------
Mb1121|M.bovis_AF2122/97 TGGSGGAGGNAGLLGVGGAGGHGASGGAGDRGGAGGTGFISSDGGAGGDG
Rv1091|M.tuberculosis_H37Rv TGGSGGAGGNAGLLGVGGAGGHGASGGAGDRGGAGGTGFISSDGGAGGDG
Mflv_5091|M.gilvum_PYR-GCK TGGAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTA
Mvan_1264|M.vanbaalenii_PYR-1 TGGAGGDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVA
MSMEG_0868|M.smegmatis_MC2_155 AGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTA
TH_3810|M.thermoresistible__bu VFGINGGNGRAGLGGRGXXXXGGGVGAAVRS-------------------
MAB_4284c|M.abscessus_ATCC_199 VGSHVGGGISESLGGSGSVGGSTAVGGGAHTGVGGGVSTG---------V
MLBr_01183|M.leprae_Br4923 --ATNHQDLIQSLLTSSSAYAGTETANHDSL-------------------
MAV_4827|M.avium_104 VQPPVRVPQPPSPPQVGGTVPQSPPQHQTPPGEGTPPKPD----------
. .
MMAR_4571|M.marinum_M GSGGSGG----AGGAGGLLRGMGGAGGTGGTGGAASGGSPAGAG------
MUL_4431|M.ulcerans_Agy99 GSGGSGG----AG---GLLRGMGGAGGTGGTG------------------
Mb1121|M.bovis_AF2122/97 GDGGNGG----AGGTGGLLFGAGGNGGPGGSGGAADIGGNGGAG------
Rv1091|M.tuberculosis_H37Rv GDGGNGG----AGGTGGLLFGAGGNGGPGGSGGAADIGGNGGAG------
Mflv_5091|M.gilvum_PYR-GCK GKGGLFG----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------
Mvan_1264|M.vanbaalenii_PYR-1 GKGGLFG----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------
MSMEG_0868|M.smegmatis_MC2_155 SQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVM
TH_3810|M.thermoresistible__bu GNGVFSG---------------GGGTPSAGFGVPTTIQFPAGSC------
MAB_4284c|M.abscessus_ATCC_199 GVGSHVG-----GGISESLGGSGSVGGSTAVGGGAHTGVGGGVNTG----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GPGNYGG---------GHVPTPGAGGSGGSGGGHVPTPGAGGSG------
MMAR_4571|M.marinum_M GTGGTGGAAGLIGVGGSGGAGGDG-------------------------L
MUL_4431|M.ulcerans_Agy99 ---GTGGAAGLIGVGGSGGAGGDG-------------------------L
Mb1121|M.bovis_AF2122/97 NGGGTDGNGGNGGSGGGAGSGGDGGGAGGNG-----------------AW
Rv1091|M.tuberculosis_H37Rv NGGGTDGNGGNGGSGGGAGSGGDGGGAGGNG-----------------AW
Mflv_5091|M.gilvum_PYR-GCK AQGATG-ATGAAGKAGATGAAGAAGAAGSAG-----------TTGAQGSA
Mvan_1264|M.vanbaalenii_PYR-1 AQGATG-ATGASGAQGSAGSAGSAGVAGSAG-----------TTGAQGSA
MSMEG_0868|M.smegmatis_MC2_155 AAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAIS
TH_3810|M.thermoresistible__bu ----TSRAVSREGIMPSSRAASAR--------------------------
MAB_4284c|M.abscessus_ATCC_199 VGVGSHVGGGISESLGGSGSVGGSTAVGG--------------------G
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --GSGGGHVPTPGTGGPGGTGGSGG------------------------G
MMAR_4571|M.marinum_M LFSDAGVGGSGGTGG-------------------------------AGGW
MUL_4431|M.ulcerans_Agy99 LFSDAGVGGSGGTGG-------------------------------AGGW
Mb1121|M.bovis_AF2122/97 LFGNGGAGGGGGKGGNGAGGGLGGGSFGLPGLNGSGGDGGDGGNGAPGGV
Rv1091|M.tuberculosis_H37Rv LFGNGGAGGGGGKGGNGAGGGLGGGSFGLPGLNGSGGDGGDGGNGAPGGV
Mflv_5091|M.gilvum_PYR-GCK GTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGEDGDAGSGGS
Mvan_1264|M.vanbaalenii_PYR-1 GTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGDAGDPGSEAV
MSMEG_0868|M.smegmatis_MC2_155 GHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGT
TH_3810|M.thermoresistible__bu --AGAACASSTSRSR---------------------------------RS
MAB_4284c|M.abscessus_ATCC_199 AHTSAINDALGGSGS-------------------------------VGGS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 HVPTPGAGTPGGSGG---------------------------GHLPFPGA
MMAR_4571|M.marinum_M FYGTGGGGGAG--------------GVSATTGNGGNGGNAG---------
MUL_4431|M.ulcerans_Agy99 FYGTGGGGGAG--------------GVSATTGNGGNGGNAG---------
Mb1121|M.bovis_AF2122/97 LYGNGGAGGQGSSGG--------IGGPGATGGAGGKGGDGGD-------A
Rv1091|M.tuberculosis_H37Rv LYGNGGAGGQGSSGG--------IGGPGATGGAGGKGGDGGD-------A
Mflv_5091|M.gilvum_PYR-GCK G-INGGAGGAGG-----------AGGEGGEGGDGGKGGAGAE--------
Mvan_1264|M.vanbaalenii_PYR-1 D-INGGAGGAGG-----------AGGEGGEGGAGGAGGDGSE--------
MSMEG_0868|M.smegmatis_MC2_155 GGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGA
TH_3810|M.thermoresistible__bu FCCSRA--------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TAVGGGAHTSAIN-------------ESMNSSINASHSSSMN--------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GSTPGGSGG----------------GHLPTPGAGTPGGGLGG--------
MMAR_4571|M.marinum_M -LIGDGG------AGGAG--AIPGAGGAGGR------IFGALGLPG----
MUL_4431|M.ulcerans_Agy99 -LIGDGG------AGGAG--AIPGAGGAGGR------IFGALGLPG----
Mb1121|M.bovis_AF2122/97 QLIGDGGNGGNGGAGGTG--GTPGPGGPGGSGGLGGLLFGQTGTAGVSP-
Rv1091|M.tuberculosis_H37Rv QLIGDGGNGGNGGAGGTG--GTPGPGGPGGSGGLGGLLFGQTGTAGVSP-
Mflv_5091|M.gilvum_PYR-GCK GGAGGGGGAGGSGAGGAG--GAGGSGGSGGSGG----SGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 GGAGGSGGAGGSGTGGAG--GAGGSGGSGGSGG----AGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 GGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADG----TPGTAGTTGANNP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --ESFGSSMGSHGAAGTG---FEAQGHAQGHAS----ETAHTTLPGAEHH
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --FGGGHAPAPGGGLGGGGGHAPAPGGGLGGFGGGHSGGGLGGLGGGHK-