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SGPEADLAGWSAAPFTGGGYTHDVFRKGSGPGVVLIPEMPGIHPGVLALGNHLVDNGFTVAIPSLFGKPG KAVSIGYVALEISRGCVAKEFAAMATNKERPVSIFLRALARDLNASTPGKGVGVIGQCFTGGFALAAAVD DSVLAPVLSQPSVPLPLTSAQRSDPGLSESELQVVADRCANEGLCAIGLRFSEDKTAPRERFSTLKARLG DAFEVIEIDSGPGNPDGFGRMAHSVLTEEVREVDGHPAYEARKRVVEFLTERLSQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4365 | - | - | 100% (266) | hypothetical protein MMAR_4365 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2080 | - | 3e-05 | 24.77% (109) | hypothetical protein Mb2080 |
| M. gilvum PYR-GCK | Mflv_2068 | - | 1e-112 | 75.09% (265) | dienelactone hydrolase |
| M. tuberculosis H37Rv | Rv2054 | - | 3e-05 | 24.77% (109) | hypothetical protein Rv2054 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3510c | - | 1e-54 | 44.19% (267) | putative dienelactone hydrolase |
| M. avium 104 | MAV_1224 | - | 1e-125 | 81.44% (264) | dienelactone hydrolase family protein |
| M. smegmatis MC2 155 | MSMEG_5236 | - | 1e-110 | 74.81% (262) | dienelactone hydrolase family protein |
| M. thermoresistible (build 8) | TH_0562 | - | 1e-117 | 75.85% (265) | dienelactone hydrolase family protein |
| M. ulcerans Agy99 | MUL_0178 | - | 1e-150 | 99.25% (266) | hypothetical protein MUL_0178 |
| M. vanbaalenii PYR-1 | Mvan_4646 | - | 1e-112 | 75.94% (266) | hypothetical protein Mvan_4646 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4365|M.marinum_M ------------------MSGPEADLAGWSAAPFTGGGYTHDVFRKGSGP
MUL_0178|M.ulcerans_Agy99 ------------------MSGPEADLAGWSAAPFTGGGYTHDVFRKGSGP
MAV_1224|M.avium_104 ------------------MTAPEADLSGWSVAPFSGGGYTHDVYRKGVGP
MSMEG_5236|M.smegmatis_MC2_155 ----------MAARNSDTSEYPVADLTGWSAAPFTAAGQTYDVYRKGEGP
TH_0562|M.thermoresistible__bu ----------MTA--------PEADLTGWSAAPFTAAGFTYDVYRKGEGP
Mflv_2068|M.gilvum_PYR-GCK MNASGHTPGTARTSEGAAGAAPEADLTGWTAAPFTAAGFTYDVYRRGDGP
Mvan_4646|M.vanbaalenii_PYR-1 ------------------MSGPEADLRGWTAEPFTAAGLTYDVYRKGEGP
MAB_3510c|M.abscessus_ATCC_199 --------------------MADDDLRDFEAGTFTHEGETKIVLRKGSGP
Mb2080|M.bovis_AF2122/97 -----------------------MTTIEIDAPAGPIDALLGLPPGQGPWP
Rv2054|M.tuberculosis_H37Rv -----------------------MTTIEIDAPAGPIDALLGLPPGQGPWP
. . . . :* *
MMAR_4365|M.marinum_M GVVLIPEMPGIHPGVLALGNHLVDNGFTVAIPSLFGKPGKAV--------
MUL_0178|M.ulcerans_Agy99 GVVLIPEMPGIHPGVLALGNHLVDNGFTVAIPSLFGKPGKAV--------
MAV_1224|M.avium_104 GVVLIPELPGIHPGVLALGNHLVDNGFTVAMPSLFGEPGKPV--------
MSMEG_5236|M.smegmatis_MC2_155 GVVLIPELPGLHPGVLGLGDHLVEAGFTVAAPSLFGTPEKPP--------
TH_0562|M.thermoresistible__bu GVVLIPEMPGLHPGVLALGNHLVDNGFTVAAPSLFGTPLKSI--------
Mflv_2068|M.gilvum_PYR-GCK GVVLIPEMPGLHPGVLALGNHLVDNGFTVAAPSLYGTPGAPG--------
Mvan_4646|M.vanbaalenii_PYR-1 GVVLIPEMPGLHPGVLALGNHLVDNGFTVWAPSLFGTPGAPA--------
MAB_3510c|M.abscessus_ATCC_199 AVIVIAEMPGISPRVADFARKVADIGCTAVMPHLFGNPGQSVDPKADGWL
Mb2080|M.bovis_AF2122/97 GVVVVHDAVGYVPDNKLISERIARAGYVVLTPNMYARGGRAR--------
Rv2054|M.tuberculosis_H37Rv GVVVVHDAVGYVPDNKLISERIARAGYVVLTPNMYARGGRAR--------
.*::: : * * :. ::. * .. * ::. .
MMAR_4365|M.marinum_M -SIGYVALEISRGCVAKEFAAMATNKERPVSIFLRALARDLNASTPGKGV
MUL_0178|M.ulcerans_Agy99 -SIGYVALEISRGCVAKEFAAMATNKERPVSIFLRALARDLNASTPGKGV
MAV_1224|M.avium_104 -SPGYLVAGMTRACVAREFAAFATNKQRPVSLFLRALARDLNASTPGDGV
MSMEG_5236|M.smegmatis_MC2_155 -MGPGAVPVIVKACVTREFAAFATNADRPVAHYLRALARDLNARTPGKGV
TH_0562|M.thermoresistible__bu -TSPSAALTLVRGCVAREFAAFATNADRPVARYLRALARDLNERTPGRGV
Mflv_2068|M.gilvum_PYR-GCK -IRPGAVPVMVRGCVAKEFAAFATNADRPIAHYLRALARDLNERTPGRGV
Mvan_4646|M.vanbaalenii_PYR-1 -LGPGALPVLMKGCIAKEFAAFATNADRPVAHYLRALARELNDDTPGKGV
MAB_3510c|M.abscessus_ATCC_199 RTSTYMASSMFRGCVSREFTVLATGKTSSVINWLRALAQNEHERNGGPGV
Mb2080|M.bovis_AF2122/97 -------------CITRVFRELLTKRGRALDDILAARDHLLAMPECSGRV
Rv2054|M.tuberculosis_H37Rv -------------CITRVFRELLTKRGRALDDILAARDHLLAMPECSGRV
*::: * : * .: * * : . *
MMAR_4365|M.marinum_M GVIGQCFTGGFALAAAVDDSVLAPVLSQPSVPLPLTSAQRSDPGLSESEL
MUL_0178|M.ulcerans_Agy99 GVIGQCFTGGFALAAAVDDSVLAPVLSQPSVPLPLTSAQRSDPGLRESEL
MAV_1224|M.avium_104 GVIGQCFTGGFALAAAVDESVLAPVLSQPSVPFPLGATRRRDPGVSEAEL
MSMEG_5236|M.smegmatis_MC2_155 GVIGQCFTGGFALAAAVDDSVLAPVLSQPSLPLPLTPRHKRDPGLSEEEL
TH_0562|M.thermoresistible__bu GVIGQCFTGGFALAAAVDDSVLAPVLSQPSLPMPLTARHRRDPGVSEGEL
Mflv_2068|M.gilvum_PYR-GCK GVIGECWSGGFALAAAVDDSVLAPVLSQPSLPLGITARHRADPGLSEAEL
Mvan_4646|M.vanbaalenii_PYR-1 GVIGQCFTGGFALAAAVDDSVLAPVMSQPSLPLPLTPKQRRDPGLSEAEL
MAB_3510c|M.abscessus_ATCC_199 GAIGMCFTGGYALAMAADDRLLAPVLSQPSLPFGLSKKARYNIDISPEDL
Mb2080|M.bovis_AF2122/97 GIVGFCMGGQFALVLSPRGFGATAPFYGTPLPRHLSETLN----------
Rv2054|M.tuberculosis_H37Rv GIVGFCMGGQFALVLSPRGFGATAPFYGTPLPRHLSETLN----------
* :* * * :**. : :. : ..:* : .
MMAR_4365|M.marinum_M QVVADRCANEGLCAIGLRFSEDKTAPRERFSTLKARLGDAFEVIEIDSGP
MUL_0178|M.ulcerans_Agy99 QVVALRCANEGLCAIGLRFSEDKTAPRERFSTLKARLGDAFEVIEIDSGP
MAV_1224|M.avium_104 ATVADRCANEGLCAMGLRFSEDWTSPRERFTALKQRLGDAFEVIEIDSRP
MSMEG_5236|M.smegmatis_MC2_155 TIVEKRAADEGLCALGLRFSQDWMAPGERFSTLKQRLGDAFEVIEIDSRK
TH_0562|M.thermoresistible__bu RIVEQRAVNDGLCALGLRFSEDRLAPAERFQTLKQRLGDAFEVIEIDSSR
Mflv_2068|M.gilvum_PYR-GCK QVVERRAAEEGLCALGLRFSEDPLVPAARFATLKKRLGDAFEVIEIDSKK
Mvan_4646|M.vanbaalenii_PYR-1 AVIERRAADEGLCALGLRFSEDPMAPAARFTTLKARLGDAFEVIEISSKR
MAB_3510c|M.abscessus_ATCC_199 SKVKHRCQHEGLKVIGMRFTTDKLVPAERFQFLRDELGDAFIAIELPGES
Mb2080|M.bovis_AF2122/97 ----------GACPIVASFGTRDPLGIGAANRLRKVTAAKNIPADIKSYP
Rv2054|M.tuberculosis_H37Rv ----------GACPIVASFGTRDPLGIGAANRLRKVTAAKNIPADIKSYP
* : * *: . :: .
MMAR_4365|M.marinum_M GNPDGFGRMAHSVLTEEVREV--DGHPAYEARKRVVEFLTERLSQ-----
MUL_0178|M.ulcerans_Agy99 GNPDGFGRMAHSVLTEEVREV--DGHPAYEARKRVVEFLTERLSQ-----
MAV_1224|M.avium_104 GNEHGFGKTAHSVLTLEVREV--DGHPAYEARKRVVEFLTQRLGAR----
MSMEG_5236|M.smegmatis_MC2_155 GNPHGFGKSAHSVLTQEVREV--DGHPAYEARKRVVQFLTERLAS-----
TH_0562|M.thermoresistible__bu GNPHGFSPLAHSVLTDQVREV--EGHPAYEARKRVVEFLTERLS------
Mflv_2068|M.gilvum_PYR-GCK GNAHGFGRMAHSVLTLEVREV--DGHPAYEARKRVVEFLTERLT------
Mvan_4646|M.vanbaalenii_PYR-1 GNPHGIGRAAHSVLTDQVVER--DGHPAYEARKRVVEFLTERLT------
MAB_3510c|M.abscessus_ATCC_199 ARP-GSPMPPHSVVTEHLIDE--PGQPTRAALDQVLDLFRSRLLTSV---
Mb2080|M.bovis_AF2122/97 GAGHSFANKLPGQPLVRIAGFGYNEAATEDAWRRVFEFFGQHLRAGSPGE
Rv2054|M.tuberculosis_H37Rv GAGHSFANKLPGQPLVRIAGFGYNEAATEDAWRRVFEFFGQHLRAGSPGE
. . . .: .: * :*.::: .:*
MMAR_4365|M.marinum_M -
MUL_0178|M.ulcerans_Agy99 -
MAV_1224|M.avium_104 -
MSMEG_5236|M.smegmatis_MC2_155 -
TH_0562|M.thermoresistible__bu -
Mflv_2068|M.gilvum_PYR-GCK -
Mvan_4646|M.vanbaalenii_PYR-1 -
MAB_3510c|M.abscessus_ATCC_199 -
Mb2080|M.bovis_AF2122/97 P
Rv2054|M.tuberculosis_H37Rv P