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SGPEADLRGWTAEPFTAAGLTYDVYRKGEGPGVVLIPEMPGLHPGVLALGNHLVDNGFTVWAPSLFGTPG APALGPGALPVLMKGCIAKEFAAFATNADRPVAHYLRALARELNDDTPGKGVGVIGQCFTGGFALAAAVD DSVLAPVMSQPSLPLPLTPKQRRDPGLSEAELAVIERRAADEGLCALGLRFSEDPMAPAARFTTLKARLG DAFEVIEISSKRGNPHGIGRAAHSVLTDQVVERDGHPAYEARKRVVEFLTERLT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4646 | - | - | 100% (265) | hypothetical protein Mvan_4646 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2068 | - | 1e-127 | 81.82% (264) | dienelactone hydrolase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3510c | - | 1e-50 | 40.67% (268) | putative dienelactone hydrolase |
| M. marinum M | MMAR_4365 | - | 1e-112 | 75.94% (266) | hypothetical protein MMAR_4365 |
| M. avium 104 | MAV_1224 | - | 1e-107 | 72.08% (265) | dienelactone hydrolase family protein |
| M. smegmatis MC2 155 | MSMEG_5236 | - | 1e-124 | 80.46% (261) | dienelactone hydrolase family protein |
| M. thermoresistible (build 8) | TH_0562 | - | 1e-121 | 79.25% (265) | dienelactone hydrolase family protein |
| M. ulcerans Agy99 | MUL_0178 | - | 1e-112 | 75.56% (266) | hypothetical protein MUL_0178 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4646|M.vanbaalenii_PYR-1 ------------------MSGPEADLRGWTAEPFTAAGLTYDVYRKGEGP
Mflv_2068|M.gilvum_PYR-GCK MNASGHTPGTARTSEGAAGAAPEADLTGWTAAPFTAAGFTYDVYRRGDGP
MSMEG_5236|M.smegmatis_MC2_155 --------MAARNSD--TSEYPVADLTGWSAAPFTAAGQTYDVYRKGEGP
TH_0562|M.thermoresistible__bu ------------------MTAPEADLTGWSAAPFTAAGFTYDVYRKGEGP
MMAR_4365|M.marinum_M ------------------MSGPEADLAGWSAAPFTGGGYTHDVFRKGSGP
MUL_0178|M.ulcerans_Agy99 ------------------MSGPEADLAGWSAAPFTGGGYTHDVFRKGSGP
MAV_1224|M.avium_104 ------------------MTAPEADLSGWSVAPFSGGGYTHDVYRKGVGP
MAB_3510c|M.abscessus_ATCC_199 --------------------MADDDLRDFEAGTFTHEGETKIVLRKGSGP
. ** .: . .*: * * * *:* **
Mvan_4646|M.vanbaalenii_PYR-1 GVVLIPEMPGLHPGVLALGNHLVDNGFTVWAPSLFGTPGAPA--------
Mflv_2068|M.gilvum_PYR-GCK GVVLIPEMPGLHPGVLALGNHLVDNGFTVAAPSLYGTPGAPG--------
MSMEG_5236|M.smegmatis_MC2_155 GVVLIPELPGLHPGVLGLGDHLVEAGFTVAAPSLFGTPEKPP--------
TH_0562|M.thermoresistible__bu GVVLIPEMPGLHPGVLALGNHLVDNGFTVAAPSLFGTPLKSI--------
MMAR_4365|M.marinum_M GVVLIPEMPGIHPGVLALGNHLVDNGFTVAIPSLFGKPGKAV--------
MUL_0178|M.ulcerans_Agy99 GVVLIPEMPGIHPGVLALGNHLVDNGFTVAIPSLFGKPGKAV--------
MAV_1224|M.avium_104 GVVLIPELPGIHPGVLALGNHLVDNGFTVAMPSLFGEPGKPV--------
MAB_3510c|M.abscessus_ATCC_199 AVIVIAEMPGISPRVADFARKVADIGCTAVMPHLFGNPGQSVDPKADGWL
.*::*.*:**: * * :. ::.: * *. * *:* * .
Mvan_4646|M.vanbaalenii_PYR-1 -LGPGALPVLMKGCIAKEFAAFATNADRPVAHYLRALARELNDDTPGKGV
Mflv_2068|M.gilvum_PYR-GCK -IRPGAVPVMVRGCVAKEFAAFATNADRPIAHYLRALARDLNERTPGRGV
MSMEG_5236|M.smegmatis_MC2_155 -MGPGAVPVIVKACVTREFAAFATNADRPVAHYLRALARDLNARTPGKGV
TH_0562|M.thermoresistible__bu -TSPSAALTLVRGCVAREFAAFATNADRPVARYLRALARDLNERTPGRGV
MMAR_4365|M.marinum_M -SIGYVALEISRGCVAKEFAAMATNKERPVSIFLRALARDLNASTPGKGV
MUL_0178|M.ulcerans_Agy99 -SIGYVALEISRGCVAKEFAAMATNKERPVSIFLRALARDLNASTPGKGV
MAV_1224|M.avium_104 -SPGYLVAGMTRACVAREFAAFATNKQRPVSLFLRALARDLNASTPGDGV
MAB_3510c|M.abscessus_ATCC_199 RTSTYMASSMFRGCVSREFTVLATGKTSSVINWLRALAQNEHERNGGPGV
: :.*:::**:.:**. .: :*****:: : . * **
Mvan_4646|M.vanbaalenii_PYR-1 GVIGQCFTGGFALAAAVDDSVLAPVMSQPSLPLPLTPKQRRDPGLSEAEL
Mflv_2068|M.gilvum_PYR-GCK GVIGECWSGGFALAAAVDDSVLAPVLSQPSLPLGITARHRADPGLSEAEL
MSMEG_5236|M.smegmatis_MC2_155 GVIGQCFTGGFALAAAVDDSVLAPVLSQPSLPLPLTPRHKRDPGLSEEEL
TH_0562|M.thermoresistible__bu GVIGQCFTGGFALAAAVDDSVLAPVLSQPSLPMPLTARHRRDPGVSEGEL
MMAR_4365|M.marinum_M GVIGQCFTGGFALAAAVDDSVLAPVLSQPSVPLPLTSAQRSDPGLSESEL
MUL_0178|M.ulcerans_Agy99 GVIGQCFTGGFALAAAVDDSVLAPVLSQPSVPLPLTSAQRSDPGLRESEL
MAV_1224|M.avium_104 GVIGQCFTGGFALAAAVDESVLAPVLSQPSVPFPLGATRRRDPGVSEAEL
MAB_3510c|M.abscessus_ATCC_199 GAIGMCFTGGYALAMAADDRLLAPVLSQPSLPFGLSKKARYNIDISPEDL
*.** *::**:*** *.*: :****:****:*: : : : .: :*
Mvan_4646|M.vanbaalenii_PYR-1 AVIERRAADEGLCALGLRFSEDPMAPAARFTTLKARLGDAFEVIEISSKR
Mflv_2068|M.gilvum_PYR-GCK QVVERRAAEEGLCALGLRFSEDPLVPAARFATLKKRLGDAFEVIEIDSKK
MSMEG_5236|M.smegmatis_MC2_155 TIVEKRAADEGLCALGLRFSQDWMAPGERFSTLKQRLGDAFEVIEIDSRK
TH_0562|M.thermoresistible__bu RIVEQRAVNDGLCALGLRFSEDRLAPAERFQTLKQRLGDAFEVIEIDSSR
MMAR_4365|M.marinum_M QVVADRCANEGLCAIGLRFSEDKTAPRERFSTLKARLGDAFEVIEIDSGP
MUL_0178|M.ulcerans_Agy99 QVVALRCANEGLCAIGLRFSEDKTAPRERFSTLKARLGDAFEVIEIDSGP
MAV_1224|M.avium_104 ATVADRCANEGLCAMGLRFSEDWTSPRERFTALKQRLGDAFEVIEIDSRP
MAB_3510c|M.abscessus_ATCC_199 SKVKHRCQHEGLKVIGMRFTTDKLVPAERFQFLRDELGDAFIAIELPGES
: *. .:** .:*:**: * * ** *: .***** .**: .
Mvan_4646|M.vanbaalenii_PYR-1 GNPHGIGRAAHSVLTDQVVERDGHPAYEARKRVVEFLTERLT---
Mflv_2068|M.gilvum_PYR-GCK GNAHGFGRMAHSVLTLEVREVDGHPAYEARKRVVEFLTERLT---
MSMEG_5236|M.smegmatis_MC2_155 GNPHGFGKSAHSVLTQEVREVDGHPAYEARKRVVQFLTERLAS--
TH_0562|M.thermoresistible__bu GNPHGFSPLAHSVLTDQVREVEGHPAYEARKRVVEFLTERLS---
MMAR_4365|M.marinum_M GNPDGFGRMAHSVLTEEVREVDGHPAYEARKRVVEFLTERLSQ--
MUL_0178|M.ulcerans_Agy99 GNPDGFGRMAHSVLTEEVREVDGHPAYEARKRVVEFLTERLSQ--
MAV_1224|M.avium_104 GNEHGFGKTAHSVLTLEVREVDGHPAYEARKRVVEFLTQRLGAR-
MAB_3510c|M.abscessus_ATCC_199 ARP-GSPMPPHSVVTEHLIDEPGQPTRAALDQVLDLFRSRLLTSV
.. * .***:* .: : *:*: * .:*:::: .**