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M. marinum M MMAR_4162 (gdpD)

annotation: glycerolphosphodiesterase GdpD
coordinates: 5124382 - 5125290
length: 302

RSAILGAVAAVVVLGGACCVAGAAPSTAASGPMIIAHRAGAADFPENTLLAITNAVSSGVDGVWLTVQAS
EDGVAVLYRPSDLATLTDGAGPVNSKTAGQLQQLNAGWNFTEPGVDGYPYRQRPTPIPTLEQAISAVPPD
IALFLDLKQTPAQPVVSAVARVLNQTGAAERATVYSTDATITEAAAQQHLRVAESRDITRQRLLDMALNH
HCDPAPDPGKWAGFELHRSITITEEFTLGVGTSKVDAQLWDPAAVECFKSGSPMNVMGFAVKTADDYQLA
KKVGLDAVLVDSPREAQHWAR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_4162gdpD-100% (302)glycerolphosphodiesterase GdpD
M. marinum MMMAR_5394glpQ12e-1024.65% (284) glycerophosphoryl diester phosphodiesterase GlpQ1
M. marinum MMMAR_0494glpQ21e-0526.99% (163) glycerophosphoryl diester phosphodiesterase GlpQ2

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2300c-1e-12774.07% (297) glycerolphosphodiesterase
M. gilvum PYR-GCKMflv_1140-1e-0828.57% (168) glycerophosphodiester phosphodiesterase
M. tuberculosis H37RvRv2277c-1e-12674.40% (293) glycerolphosphodiesterase
M. leprae Br4923MLBr_00074glpQ4e-0927.51% (189) putative glycerophosphoryl diester phosphodiesterase
M. abscessus ATCC 19977MAB_0123-2e-1029.34% (167) putative glycerophosphoryl diester phosphodiesterase
M. avium 104MAV_0186-2e-1027.36% (201) glycerophosphoryl diester phosphodiesterase family protein
M. smegmatis MC2 155MSMEG_6423-7e-0936.05% (86) glycerophosphoryl diester phosphodiesterase family protein
M. thermoresistible (build 8)TH_0749glpQ16e-0828.21% (156) PROBABLE GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLPQ1
M. ulcerans Agy99MUL_4025gdpD1e-17299.01% (302) glycerolphosphodiesterase GdpD
M. vanbaalenii PYR-1Mvan_5667-7e-0826.23% (183) glycerophosphoryl diester phosphodiesterase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1140|M.gilvum_PYR-GCK          ----------------------MSSGATLGG--HPFVVAHRGASADRPEH
Mvan_5667|M.vanbaalenii_PYR-1       ----------------------MSSGETFGG--HPFVVAHRGASADRPEH
MSMEG_6423|M.smegmatis_MC2_155      -------MTEAD---------AGADGQAPTGPTHPFVVAHRGASADRPEH
MAB_0123|M.abscessus_ATCC_1997      -------MTESSEPGEDEAHARGADGIDGRGERHPFVVAHRGASADRPEH
MLBr_00074|M.leprae_Br4923          ---------------------MMLADEVFAG--HPFVVAHRGASAVLPEH
MAV_0186|M.avium_104                ---------------------MTWADEVLAG--HPFVVAHRGASAARPEH
TH_0749|M.thermoresistible__bu      ---------------------METGGEALGR--HPYVVAHRGASADRPEH
MMAR_4162|M.marinum_M               MRSAILG--AVAAVVVLGGACCVAGAAPSTAASGPMIIAHRAGAADFPEN
MUL_4025|M.ulcerans_Agy99           MRSAILG--AVAAVAVLGGACCVAGAAPSTAASGPMIIAHRAGAADFPEN
Mb2300c|M.bovis_AF2122/97           ----MLG--AVALVIALGGTCGVADALPLGQTDDPMIVAHRAGTRDFPEN
Rv2277c|M.tuberculosis_H37Rv        ----MPGRFTVALVIALGGTCGVADALPLGQTDDPMIVAHRAGTRDFPEN
                                                                      * ::***..:   **:

Mflv_1140|M.gilvum_PYR-GCK          TLAAYQLALEEGADAVECDVRLTRDGHLVCVHDRRLDRTSSGTGLVSDMT
Mvan_5667|M.vanbaalenii_PYR-1       TLAAYELALGEGADAVECDVRLTRDGHLVCVHDRRLDRTSTGSGLVSEMT
MSMEG_6423|M.smegmatis_MC2_155      TLAAYDLALQEGADGLECDVRLTRDGHLVCVHDRKVDRTSTGTGLVSEMT
MAB_0123|M.abscessus_ATCC_1997      TLAAYELALEEGADGVECDVRLTRDGQLVCVHDRRVDRTSDGTGLVSEMT
MLBr_00074|M.leprae_Br4923          TLAAYELALKEGADGVECDVRLTRDGHMVCVHDRRLDRTSTGVGLVSTMT
MAV_0186|M.avium_104                TLAAYDLALKEGADGVECDVRLTRDGHLVCVHDRRLDRTSTGAGLVSTMT
TH_0749|M.thermoresistible__bu      TLAAYELALEEGADGLECDVRLTRDGQLVCVHDRRVDRTSTGSGVISTMT
MMAR_4162|M.marinum_M               TLLAITNAVSSGVDGVWLTVQASEDGVAVLYRPSDLATLTDGAGPVNSKT
MUL_4025|M.ulcerans_Agy99           TLLAITNAVSSGVDGVWLTVQASEDGVAVLYRPSDLGTLTDGAGPVNSKT
Mb2300c|M.bovis_AF2122/97           TVLAITNAVAAGVDGMWLTVQVSSDGVPVLYRPSDLATLTDGAGPVNSKT
Rv2277c|M.tuberculosis_H37Rv        TVLAITNAVAAGVDGMWLTVQVSSDGVPVLYRPSDLATLTDGAGPVNSKT
                                    *: *   *:  *.*.:   *: : **  *  :   :   : * * :.  *

Mflv_1140|M.gilvum_PYR-GCK          LAQLRELDFGAWHPSRRDDVSGGDTGLLTLDDLVSLVMDWNRPVKMFIET
Mvan_5667|M.vanbaalenii_PYR-1       LAQLRDFDFGSWHPSWRADGSHGDTGLLTLDDLVRLVLDWNRPVKMFIET
MSMEG_6423|M.smegmatis_MC2_155      LAELRKLNFGSWHPSWRADSSGDDTGVLTLDELVRMALDWNRPVKLFIET
MAB_0123|M.abscessus_ATCC_1997      LSQLRALDFGSWHPGGAEAETG--TGLLTLEELVSLVLDWNRPVKLFIET
MLBr_00074|M.leprae_Br4923          LAQLRALEYGAWHNSWRPDGTHGDTGLLTLDALVSLVLDWHRPVKIFVET
MAV_0186|M.avium_104                LAQLRELEYGAWHDSWREDGAHGDTSLLTLDALVSLVLDWRRPVKLFIET
TH_0749|M.thermoresistible__bu      LDELRRLDFGAWHDSWQP--VYGTFGLLTLEELIGLVLGWKRPVKLFIET
MMAR_4162|M.marinum_M               AGQLQQLNAGWNFTEPGVDGYPYRQRPTPIPTLEQAISAVPPDIALFLDL
MUL_4025|M.ulcerans_Agy99           AGQLQQLNAGWNFTEPGVDGYPYRQRPTPIPTLEQAISAVPPDIALFLDL
Mb2300c|M.bovis_AF2122/97           VQQLQQLNAGWNFTTPGVEGHPYRQRATPIPTLEQAIGATPPDMTLFLDP
Rv2277c|M.tuberculosis_H37Rv        VQQLQQLNAGWNFTTPGVEGHPYRQRATPIPTLEQAIGATPPDMTLFLDL
                                      :*: :: *  .               .:  *          : :*:: 

Mflv_1140|M.gilvum_PYR-GCK          KHP-------------VRYGGLVESKVLALLHRYGIASPASADMARAVVM
Mvan_5667|M.vanbaalenii_PYR-1       KHP-------------VRYGALVESKVLALLHRYGIASPASADLSRAVVM
MSMEG_6423|M.smegmatis_MC2_155      KHP-------------VRYGALVENKLLALLHRYGIAAPASADMARAVVM
MAB_0123|M.abscessus_ATCC_1997      KHP-------------VRYGSLVENKVLALLHRFGIAAPASADMSRAVVM
MLBr_00074|M.leprae_Br4923          KHP-------------VRYGALVESKLLALLHRFGIAAPASADRSRAVVM
MAV_0186|M.avium_104                KHP-------------VRYGSLVETKLLALLHRFGIAAPASADRSRAVVM
TH_0749|M.thermoresistible__bu      KHP-------------VRYGGLVESKVLAMLHRFGIASPPSARLSRAVIM
MMAR_4162|M.marinum_M               KQTPAQPVVSAVARVLNQTGAAERATVYSTDATITEAAAQQH-LRVAESR
MUL_4025|M.ulcerans_Agy99           KQTPAQPVVSAVARVLNQTGAAERATVYSTDATITEAAAQQH-LRVAESR
Mb2300c|M.bovis_AF2122/97           KQTPPQPLVSAVAQVLTRTGAAGRSIVYSTNADITAAASRQEGLQVAESR
Rv2277c|M.tuberculosis_H37Rv        KQTPPQPLVSAVAQVLTRTGAAGRSIVYSTNADITAAASRQEGLQVAESR
                                    *:.              : *.  .  : :       *:. .     *   

Mflv_1140|M.gilvum_PYR-GCK          SFSAGAVWRIRRAAPMLPTVLLGETSRYLGGGAATTVGATAVGP----SI
Mvan_5667|M.vanbaalenii_PYR-1       SFSAAAVWRIRRAAPLLPTVLLGETSRYLGGSAATTVGATAVGP----SI
MSMEG_6423|M.smegmatis_MC2_155      SFSAAAVWRIRRAAPMLPTVLLGETSRYLGGSAATTVGATAVGP----SI
MAB_0123|M.abscessus_ATCC_1997      SFSAAAVWRIRRAAPMLPTVLLGETSRYLGGSAATTVGATAVGP----SI
MLBr_00074|M.leprae_Br4923          SFSAAAVWRVRRAAPLLPTVLLGRAGRYLTSSAATAVGATAVGP----SL
MAV_0186|M.avium_104                SFSASAVWRIRRAAPLLPTVLLGKTARYLISGAPTAVGATAVGP----SL
TH_0749|M.thermoresistible__bu      X-------GRRRSTTWRPA-------------------------------
MMAR_4162|M.marinum_M               DITRQRLLDMALNHHCDPAPDPGKWAGFELHRSITITEEFTLGVGTSKVD
MUL_4025|M.ulcerans_Agy99           DITRQRLLDMALNHHCDPAPDPGKWAGFELHRSITITEEFTLGVETSKVD
Mb2300c|M.bovis_AF2122/97           DVTRQRLFNMALNHHCDPQPDPGKWAGFELHRDVTVTEEFTLGSGISAVN
Rv2277c|M.tuberculosis_H37Rv        DVTRQRLFNMALNHHCDPQPDPGKWAGFELHRDVTVTEEFTLGSGISAVN
                                                     *                                

Mflv_1140|M.gilvum_PYR-GCK          ATLREHPELVDRAAAQGRALYCWTVDHYEDVQYCADLGVAWIATNHPGRT
Mvan_5667|M.vanbaalenii_PYR-1       ATLREHPELVDRAAAQGRALYCWTVDHYEDVEYCRDLGVAWIATNHPGRT
MSMEG_6423|M.smegmatis_MC2_155      ATLREHPELVDRAAAQGRALYCWTVDHYEDVRFCRDVGVAWIATNHPGRT
MAB_0123|M.abscessus_ATCC_1997      ATLREHPELVDRAAAQGRATYCWTVDHYEDVEFCRSIGVAWIATNHPGRT
MLBr_00074|M.leprae_Br4923          PALKEYPKLVDRAGAQGRAVYCWNVDDYDDIDFCRDIGVAWIATRHPGRT
MAV_0186|M.avium_104                PTLREYPQLADRAIAQGRAVYCWNVDDYQDIDFCRDVGVAWLATHHPGRT
TH_0749|M.thermoresistible__bu      --------------------------------------------------
MMAR_4162|M.marinum_M               AQLWDPAAVECFKSGSPMNVMGFAVKTADDYQLAKKVGLDAVLVDSPREA
MUL_4025|M.ulcerans_Agy99           AQLWDPAAVECFKSGSPMNVMGFAVKTADDYQLAKKVGLDAVLVDSPREA
Mb2300c|M.bovis_AF2122/97           AELWDEASVDCFRSQSGMKVMGFAVKTVDDYRLAHKIGLDAVLVDSPLAA
Rv2277c|M.tuberculosis_H37Rv        AELWDEASVDCFRSQSGMKVMGFAVKTVDDYRLAHKIGLDAVLVDSPLAA
                                                                                      

Mflv_1140|M.gilvum_PYR-GCK          KAWLQNGLTGAGRD
Mvan_5667|M.vanbaalenii_PYR-1       KGWLQDGLTGAGRD
MSMEG_6423|M.smegmatis_MC2_155      KDWLQNGLTGAGRD
MAB_0123|M.abscessus_ATCC_1997      KSWLQRGLTGTTL-
MLBr_00074|M.leprae_Br4923          KAWLQNNGRTE---
MAV_0186|M.avium_104                KAWLQGHRDGNG--
TH_0749|M.thermoresistible__bu      --------------
MMAR_4162|M.marinum_M               QHWAR---------
MUL_4025|M.ulcerans_Agy99           QHWAR---------
Mb2300c|M.bovis_AF2122/97           QQWRH---------
Rv2277c|M.tuberculosis_H37Rv        QQWRH---------