For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
PGRFTVALVIALGGTCGVADALPLGQTDDPMIVAHRAGTRDFPENTVLAITNAVAAGVDGMWLTVQVSSD GVPVLYRPSDLATLTDGAGPVNSKTVQQLQQLNAGWNFTTPGVEGHPYRQRATPIPTLEQAIGATPPDMT LFLDLKQTPPQPLVSAVAQVLTRTGAAGRSIVYSTNADITAAASRQEGLQVAESRDVTRQRLFNMALNHH CDPQPDPGKWAGFELHRDVTVTEEFTLGSGISAVNAELWDEASVDCFRSQSGMKVMGFAVKTVDDYRLAH KIGLDAVLVDSPLAAQQWRH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2277c | - | - | 100% (301) | Possible glycerolphosphodiesterase |
| M. tuberculosis H37Rv | Rv3842c | glpQ1 | 7e-07 | 35.53% (76) | glycerophosphoryl diester phosphodiesterase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2300c | - | 1e-170 | 99.66% (295) | glycerolphosphodiesterase |
| M. gilvum PYR-GCK | Mflv_1140 | - | 1e-06 | 34.21% (76) | glycerophosphodiester phosphodiesterase |
| M. leprae Br4923 | MLBr_00074 | glpQ | 9e-07 | 34.21% (76) | putative glycerophosphoryl diester phosphodiesterase |
| M. abscessus ATCC 19977 | MAB_0123 | - | 6e-08 | 31.73% (104) | putative glycerophosphoryl diester phosphodiesterase |
| M. marinum M | MMAR_4162 | gdpD | 1e-126 | 74.40% (293) | glycerolphosphodiesterase GdpD |
| M. avium 104 | MAV_0186 | - | 8e-07 | 35.53% (76) | glycerophosphoryl diester phosphodiesterase family protein |
| M. smegmatis MC2 155 | MSMEG_6423 | - | 1e-07 | 33.71% (89) | glycerophosphoryl diester phosphodiesterase family protein |
| M. thermoresistible (build 8) | TH_0749 | glpQ1 | 2e-07 | 30.48% (105) | PROBABLE GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLPQ1 |
| M. ulcerans Agy99 | MUL_4025 | gdpD | 1e-124 | 73.72% (293) | glycerolphosphodiesterase GdpD |
| M. vanbaalenii PYR-1 | Mvan_5667 | - | 5e-06 | 32.89% (76) | glycerophosphoryl diester phosphodiesterase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1140|M.gilvum_PYR-GCK ----------------------MSSGATLGG--HPFVVAHRGASADRPEH
Mvan_5667|M.vanbaalenii_PYR-1 ----------------------MSSGETFGG--HPFVVAHRGASADRPEH
MSMEG_6423|M.smegmatis_MC2_155 -------MTEAD---------AGADGQAPTGPTHPFVVAHRGASADRPEH
MAB_0123|M.abscessus_ATCC_1997 -------MTESSEPGEDEAHARGADGIDGRGERHPFVVAHRGASADRPEH
MLBr_00074|M.leprae_Br4923 ---------------------MMLADEVFAG--HPFVVAHRGASAVLPEH
MAV_0186|M.avium_104 ---------------------MTWADEVLAG--HPFVVAHRGASAARPEH
TH_0749|M.thermoresistible__bu ---------------------METGGEALGR--HPYVVAHRGASADRPEH
Rv2277c|M.tuberculosis_H37Rv ----MPGRFTVALVIALGGTCGVADALPLGQTDDPMIVAHRAGTRDFPEN
Mb2300c|M.bovis_AF2122/97 ----MLG--AVALVIALGGTCGVADALPLGQTDDPMIVAHRAGTRDFPEN
MMAR_4162|M.marinum_M MRSAILG--AVAAVVVLGGACCVAGAAPSTAASGPMIIAHRAGAADFPEN
MUL_4025|M.ulcerans_Agy99 MRSAILG--AVAAVAVLGGACCVAGAAPSTAASGPMIIAHRAGAADFPEN
* ::***..: **:
Mflv_1140|M.gilvum_PYR-GCK TLAAYQLALEEGADAVECDVRLTRDGHLVCVHDRRLDRTSSGTGLVSDMT
Mvan_5667|M.vanbaalenii_PYR-1 TLAAYELALGEGADAVECDVRLTRDGHLVCVHDRRLDRTSTGSGLVSEMT
MSMEG_6423|M.smegmatis_MC2_155 TLAAYDLALQEGADGLECDVRLTRDGHLVCVHDRKVDRTSTGTGLVSEMT
MAB_0123|M.abscessus_ATCC_1997 TLAAYELALEEGADGVECDVRLTRDGQLVCVHDRRVDRTSDGTGLVSEMT
MLBr_00074|M.leprae_Br4923 TLAAYELALKEGADGVECDVRLTRDGHMVCVHDRRLDRTSTGVGLVSTMT
MAV_0186|M.avium_104 TLAAYDLALKEGADGVECDVRLTRDGHLVCVHDRRLDRTSTGAGLVSTMT
TH_0749|M.thermoresistible__bu TLAAYELALEEGADGLECDVRLTRDGQLVCVHDRRVDRTSTGSGVISTMT
Rv2277c|M.tuberculosis_H37Rv TVLAITNAVAAGVDGMWLTVQVSSDGVPVLYRPSDLATLTDGAGPVNSKT
Mb2300c|M.bovis_AF2122/97 TVLAITNAVAAGVDGMWLTVQVSSDGVPVLYRPSDLATLTDGAGPVNSKT
MMAR_4162|M.marinum_M TLLAITNAVSSGVDGVWLTVQASEDGVAVLYRPSDLATLTDGAGPVNSKT
MUL_4025|M.ulcerans_Agy99 TLLAITNAVSSGVDGVWLTVQASEDGVAVLYRPSDLGTLTDGAGPVNSKT
*: * *: *.*.: *: : ** * : : : * * :. *
Mflv_1140|M.gilvum_PYR-GCK LAQLRELDFGAWHPSRRDDVSGGDTGLLTLDDLVSLVMDWNRPVKMFIET
Mvan_5667|M.vanbaalenii_PYR-1 LAQLRDFDFGSWHPSWRADGSHGDTGLLTLDDLVRLVLDWNRPVKMFIET
MSMEG_6423|M.smegmatis_MC2_155 LAELRKLNFGSWHPSWRADSSGDDTGVLTLDELVRMALDWNRPVKLFIET
MAB_0123|M.abscessus_ATCC_1997 LSQLRALDFGSWHPGGAEAETG--TGLLTLEELVSLVLDWNRPVKLFIET
MLBr_00074|M.leprae_Br4923 LAQLRALEYGAWHNSWRPDGTHGDTGLLTLDALVSLVLDWHRPVKIFVET
MAV_0186|M.avium_104 LAQLRELEYGAWHDSWREDGAHGDTSLLTLDALVSLVLDWRRPVKLFIET
TH_0749|M.thermoresistible__bu LDELRRLDFGAWHDSWQP--VYGTFGLLTLEELIGLVLGWKRPVKLFIET
Rv2277c|M.tuberculosis_H37Rv VQQLQQLNAGWNFTTPGVEGHPYRQRATPIPTLEQAIGATPPDMTLFLDL
Mb2300c|M.bovis_AF2122/97 VQQLQQLNAGWNFTTPGVEGHPYRQRATPIPTLEQAIGATPPDMTLFLDP
MMAR_4162|M.marinum_M AGQLQQLNAGWNFTEPGVDGYPYRQRPTPIPTLEQAISAVPPDIALFLDL
MUL_4025|M.ulcerans_Agy99 AGQLQQLNAGWNFTEPGVDGYPYRQRPTPIPTLEQAISAVPPDIALFLDL
:*: :: * . .: * : :*::
Mflv_1140|M.gilvum_PYR-GCK KHP-------------VRYGGLVESKVLALLHRYGIASPASADMARAVVM
Mvan_5667|M.vanbaalenii_PYR-1 KHP-------------VRYGALVESKVLALLHRYGIASPASADLSRAVVM
MSMEG_6423|M.smegmatis_MC2_155 KHP-------------VRYGALVENKLLALLHRYGIAAPASADMARAVVM
MAB_0123|M.abscessus_ATCC_1997 KHP-------------VRYGSLVENKVLALLHRFGIAAPASADMSRAVVM
MLBr_00074|M.leprae_Br4923 KHP-------------VRYGALVESKLLALLHRFGIAAPASADRSRAVVM
MAV_0186|M.avium_104 KHP-------------VRYGSLVETKLLALLHRFGIAAPASADRSRAVVM
TH_0749|M.thermoresistible__bu KHP-------------VRYGGLVESKVLAMLHRFGIASPPSARLSRAVIM
Rv2277c|M.tuberculosis_H37Rv KQTPPQPLVSAVAQVLTRTGAAGRSIVYSTNADITAAASRQEGLQVAESR
Mb2300c|M.bovis_AF2122/97 KQTPPQPLVSAVAQVLTRTGAAGRSIVYSTNADITAAASRQEGLQVAESR
MMAR_4162|M.marinum_M KQTPAQPVVSAVARVLNQTGAAERATVYSTDATITEAAAQQH-LRVAESR
MUL_4025|M.ulcerans_Agy99 KQTPAQPVVSAVARVLNQTGAAERATVYSTDATITEAAAQQH-LRVAESR
*:. : *. . : : *:. . *
Mflv_1140|M.gilvum_PYR-GCK SFSAGAVWRIRRAAPMLPTVLLGETSRYLGGGAATTVGATAVGP----SI
Mvan_5667|M.vanbaalenii_PYR-1 SFSAAAVWRIRRAAPLLPTVLLGETSRYLGGSAATTVGATAVGP----SI
MSMEG_6423|M.smegmatis_MC2_155 SFSAAAVWRIRRAAPMLPTVLLGETSRYLGGSAATTVGATAVGP----SI
MAB_0123|M.abscessus_ATCC_1997 SFSAAAVWRIRRAAPMLPTVLLGETSRYLGGSAATTVGATAVGP----SI
MLBr_00074|M.leprae_Br4923 SFSAAAVWRVRRAAPLLPTVLLGRAGRYLTSSAATAVGATAVGP----SL
MAV_0186|M.avium_104 SFSASAVWRIRRAAPLLPTVLLGKTARYLISGAPTAVGATAVGP----SL
TH_0749|M.thermoresistible__bu X-------GRRRSTTWRPA-------------------------------
Rv2277c|M.tuberculosis_H37Rv DVTRQRLFNMALNHHCDPQPDPGKWAGFELHRDVTVTEEFTLGSGISAVN
Mb2300c|M.bovis_AF2122/97 DVTRQRLFNMALNHHCDPQPDPGKWAGFELHRDVTVTEEFTLGSGISAVN
MMAR_4162|M.marinum_M DITRQRLLDMALNHHCDPAPDPGKWAGFELHRSITITEEFTLGVGTSKVD
MUL_4025|M.ulcerans_Agy99 DITRQRLLDMALNHHCDPAPDPGKWAGFELHRSITITEEFTLGVETSKVD
*
Mflv_1140|M.gilvum_PYR-GCK ATLREHPELVDRAAAQGRALYCWTVDHYEDVQYCADLGVAWIATNHPGRT
Mvan_5667|M.vanbaalenii_PYR-1 ATLREHPELVDRAAAQGRALYCWTVDHYEDVEYCRDLGVAWIATNHPGRT
MSMEG_6423|M.smegmatis_MC2_155 ATLREHPELVDRAAAQGRALYCWTVDHYEDVRFCRDVGVAWIATNHPGRT
MAB_0123|M.abscessus_ATCC_1997 ATLREHPELVDRAAAQGRATYCWTVDHYEDVEFCRSIGVAWIATNHPGRT
MLBr_00074|M.leprae_Br4923 PALKEYPKLVDRAGAQGRAVYCWNVDDYDDIDFCRDIGVAWIATRHPGRT
MAV_0186|M.avium_104 PTLREYPQLADRAIAQGRAVYCWNVDDYQDIDFCRDVGVAWLATHHPGRT
TH_0749|M.thermoresistible__bu --------------------------------------------------
Rv2277c|M.tuberculosis_H37Rv AELWDEASVDCFRSQSGMKVMGFAVKTVDDYRLAHKIGLDAVLVDSPLAA
Mb2300c|M.bovis_AF2122/97 AELWDEASVDCFRSQSGMKVMGFAVKTVDDYRLAHKIGLDAVLVDSPLAA
MMAR_4162|M.marinum_M AQLWDPAAVECFKSGSPMNVMGFAVKTADDYQLAKKVGLDAVLVDSPREA
MUL_4025|M.ulcerans_Agy99 AQLWDPAAVECFKSGSPMNVMGFAVKTADDYQLAKKVGLDAVLVDSPREA
Mflv_1140|M.gilvum_PYR-GCK KAWLQNGLTGAGRD
Mvan_5667|M.vanbaalenii_PYR-1 KGWLQDGLTGAGRD
MSMEG_6423|M.smegmatis_MC2_155 KDWLQNGLTGAGRD
MAB_0123|M.abscessus_ATCC_1997 KSWLQRGLTGTTL-
MLBr_00074|M.leprae_Br4923 KAWLQNNGRTE---
MAV_0186|M.avium_104 KAWLQGHRDGNG--
TH_0749|M.thermoresistible__bu --------------
Rv2277c|M.tuberculosis_H37Rv QQWRH---------
Mb2300c|M.bovis_AF2122/97 QQWRH---------
MMAR_4162|M.marinum_M QHWAR---------
MUL_4025|M.ulcerans_Agy99 QHWAR---------