For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VSLVVAEPDALSNAAGHLAGIGSKIEDATAAGAGPTTTVAAAASDDVSIAISEFFGTYGKQFQTFSARAA AFHDEFVSLLRGGAAAYLDTEFANARLGQANPANSPAPAAAAPGGAFLAELSAGNTELGPITGAISVGEL LPGAPPEIGAAISVLGGGSLLPGLFGFGPFAPTTGSPAVAEGPWQTLFANTGANLQTIYSDWAAHPFPVA QQVIANQAEYARTIGGGLAAAAQDLPATVANLPANIGLAVADAVNFPAELQGYLGKQVGYGQVVVDALQN AGAELPQTLPNFFGDVDKANQAVMAGDYNDAVDYVPRAAVDLFLSGVNINNLSQITVEGPAGELLPLMSL PAQMQQDLIDLLPPGAILTQMVQNSFNATNTVVNSIALAAIGPPIATLDGFATGLTVLGGAVATGNGVGA VGALLDMPAYVLDGFLNGETVVELRVPVSETVTIPLTPLTPPIVVGANTPVLVRMPFGGVLAQPQPITAT IELPGTGSPAPLDITIPDMQVAGVVPTLLNVIPQRVAEAIAPE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3494 | - | - | 100% (533) | PE-PGRS family protein |
| M. marinum M | MMAR_2460 | - | 1e-95 | 35.90% (624) | PE-PGRS family protein |
| M. marinum M | MMAR_2458 | - | 1e-69 | 30.95% (656) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3842 | PE_PGRS62 | 2e-81 | 34.78% (575) | PE-PGRS family protein |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv3812 | PE_PGRS62 | 2e-81 | 34.78% (575) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 7e-13 | 39.33% (89) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. avium 104 | MAV_1346 | - | 3e-16 | 31.06% (264) | PE family protein |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_4350 | - | 3e-08 | 24.14% (261) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1640 | - | 2e-95 | 35.74% (624) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_5821 | - | 2e-06 | 20.34% (408) | hypothetical protein Mvan_5821 |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_01183|M.leprae_Br4923 ---------------MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQ
MAV_1346|M.avium_104 ---------------MS-FVTTRPEALLAVASMLEGLGSSMDAQNAAAAA
Mb3842|M.bovis_AF2122/97 ---------------MS-FVVTVPEAVAAAAGDLAAIGSTLREATAAAAG
Rv3812|M.tuberculosis_H37Rv ---------------MS-FVVTVPEAVAAAAGDLAAIGSTLREATAAAAG
MUL_1640|M.ulcerans_Agy99 ---------------MS-FVIADPEMVTAAAADLAGIRSTLGAAAEAAAG
MMAR_3494|M.marinum_M ---------------MS-LVVAEPDALSNAAGHLAGIGSKIEDATAAGAG
TH_4350|M.thermoresistible__bu -------------------MLASIRPYATAGVALVGAGVIAVTPVAPPPA
Mvan_5821|M.vanbaalenii_PYR-1 MQQALPVAFGAATRSLDVKSASRVNKYLVAGAAMVCAGAIAVNPVAPTNS
: .. : .
MLBr_01183|M.leprae_Br4923 LTTEIAPPAADDVSI--LLAHFFSGHGRQYQAHASQGATNHQDLIQSLLT
MAV_1346|M.avium_104 PTTSIAPAAADEVSA--LQAAQFSAYGTWYQQVSAQAKAIHQTLVQNLDT
Mb3842|M.bovis_AF2122/97 PTTGLAAAAADDVSI--AVSQLFGRYGQEFQTVSNQLAAFHTEFVRTLNR
Rv3812|M.tuberculosis_H37Rv PTTGLAAAAADDVSI--AVSQLFGRYGQEFQTVSNQLAAFHTEFVRTLNR
MUL_1640|M.ulcerans_Agy99 PTTGVAAAAADEVSA--AIAHLFGAYGQEFQALNGRAAAFHAELVRLLNG
MMAR_3494|M.marinum_M PTTTVAAAASDDVSI--AISEFFGTYGKQFQTFSARAAAFHDEFVSLLRG
TH_4350|M.thermoresistible__bu DIQVSRQAVALSAIS--NPGDPVVAYGELIANTIGSLQGLGGQFAADPAP
Mvan_5821|M.vanbaalenii_PYR-1 MPDIRQAAVQLTASTNPVLENPLLVWQNVFTNSFTQAGAIGTALWNNPFP
.. . . :
MLBr_01183|M.leprae_Br4923 SSSAYAGTETAN--------------------------------------
MAV_1346|M.avium_104 NADSYGATEAANRVNTSAAALQGLAPNVIPNAAP----------------
Mb3842|M.bovis_AF2122/97 GAAAYLNTESANGGQLFGQIEAGQRAVSAAAAA-----------------
Rv3812|M.tuberculosis_H37Rv GAAAYLNTESANGGQLFGQIEAGQRAVSAAAAA-----------------
MUL_1640|M.ulcerans_Agy99 GAASYLSAEVVNVEALLGQSLNGGAAAAADPLSGLLGSILGTSSGGSGSV
MMAR_3494|M.marinum_M GAAAYLDTEFAN--ARLGQANPANSPAPAAAAPG----------------
TH_4350|M.thermoresistible__bu VLVKILQNQIANGQLIGSALDEALGFLLQGVEALP---------------
Mvan_5821|M.vanbaalenii_PYR-1 ILNQIGENQVGHLKTIWGMTAAEAGTRRGTGLVG----------------
: :
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb3842|M.bovis_AF2122/97 --------------------------------------------------
Rv3812|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1640|M.ulcerans_Agy99 GGILGGSGGLLDPILFGGTGGLLGPLVGGNGVLTSLVGSGPLGPFFNGVG
MMAR_3494|M.marinum_M -------------------GAFLAELSAGNTELGPITGAISVGELLPGAP
TH_4350|M.thermoresistible__bu --------------------------------------------------
Mvan_5821|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb3842|M.bovis_AF2122/97 --------------------------------------------------
Rv3812|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1640|M.ulcerans_Agy99 GEIGVVTSALIGGDGAVLLSDQIGGITGTLTSLPGLSGLQTLLPGLFPSS
MMAR_3494|M.marinum_M PEIGAAISVLGGGS------------------------LLPGLFGFGPFA
TH_4350|M.thermoresistible__bu --------------------------------------------------
Mvan_5821|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 ---------------------------------------HDSL-------
MAV_1346|M.avium_104 -------------------------------AADPPPAGTTSLGTSIGWA
Mb3842|M.bovis_AF2122/97 -------APGGAYGQLVANTATNLESLYGAWSANPFPFLRQIIANQQVYW
Rv3812|M.tuberculosis_H37Rv -------APGGAYGQLVANTATNLESLYGAWSANPFPFLRQIIANQQVYW
MUL_1640|M.ulcerans_Agy99 GDTTTTPAPGGAWQQLFENTSSNLNALGTAWSEDPFPLLRQVIANQQGYA
MMAR_3494|M.marinum_M PTTGSPAVAEGPWQTLFANTGANLQTIYSDWAAHPFPVAQQVIANQAEYA
TH_4350|M.thermoresistible__bu -----------------------------GALEEAFALLTQGDLKGAVDA
Mvan_5821|M.vanbaalenii_PYR-1 ----------------------------AAEGVQRSLTNLPVRLQAAGEF
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 QNVGAAASDFITLGEGQFAPVPG---------------------------
Mb3842|M.bovis_AF2122/97 QQIAAALANAVQNFPALVANLPAAIDAAVQQFLAFNAAYYIQQIISSQIG
Rv3812|M.tuberculosis_H37Rv QQIAAALANAVQNFPALVANLPAAIDAAVQQFLAFNAAYYIQQIISSQIG
MUL_1640|M.ulcerans_Agy99 YTLGQDLSLAIQNLPTELAHLPENIETGIQGFLAFNPGLYAQQFVASTMN
MMAR_3494|M.marinum_M RTIGGGLAAAAQDLPATVANLPANIGLAVADAVNFPAEL--QGYLGKQVG
TH_4350|M.thermoresistible__bu FMMG-IIPAALGMIVPLVAGSMIITNTADNFARAVSAVLDVDAMLPTLLG
Mvan_5821|M.vanbaalenii_PYR-1 LAAGQFTEALVELNTWALVAMENLAFPLTSLLTIPKAMFDAVGRVYDSLI
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ----------------AAGIPNFNPGLTAATTAGPPAPAAPAAAAG----
Mb3842|M.bovis_AF2122/97 FAQLFATTVGQGVTSVIAGWPNLAAELQLAFQQLLVGDYNAAVANLGKAM
Rv3812|M.tuberculosis_H37Rv FAQLFATTVGQGVTSVIAGWPNLAAELQLAFQQLLVGDYNAAVANLGKAM
MUL_1640|M.ulcerans_Agy99 DFHTIGTSLSEAGQDLQIGLAGFPADMQPAYEAFAAGNYNLAVNDATKAL
MMAR_3494|M.marinum_M YGQVVVDALQNAGAELPQTLPNFFGDVDKANQAVMAGDYNDAVDYVPRAA
TH_4350|M.thermoresistible__bu FAGPVLSAVDGFVTSGQAVLDGVLAGDPIAVLNAVASTPAVLIDAVLNGS
Mvan_5821|M.vanbaalenii_PYR-1 TRGNIITISKGLMSPPITAFFAAMNVADTVFASVKEGNLKDAFTALVNAP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ---------------------------APVLASMGRGPSIGGLSVPP-SW
Mb3842|M.bovis_AF2122/97 TNLLVTGFDTSDVTIGTMGTTISVTAKPKLLGPLGDLFTIMTIPAQE-AQ
Rv3812|M.tuberculosis_H37Rv TNLLVTGFDTSDVTIGTMGTTISVTAKPKLLGPLGDLFTIMTIPAQE-AQ
MUL_1640|M.ulcerans_Agy99 LNVFITGFDTSNLN------------DIRLLGPVADLFPILALPGQD-VQ
MMAR_3494|M.marinum_M VDLFLSGVNINNLS------------QITVEGPAGELLPLMSLPAQM-QQ
TH_4350|M.thermoresistible__bu GALLGFLPLPGLLTP----------ATAPIGGPIATLLGIRNAIADA-LQ
Mvan_5821|M.vanbaalenii_PYR-1 GLITGAFLNGYKPYFG----------HDEEGNPIYSPENFPGLFSAGGTL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 APGGVAPA-----------AN-----------------------------
Mb3842|M.bovis_AF2122/97 YFTNLMPP-SILRDMSQNFTNVLTTLSNPNIQAVASFDIATTAGTLSTFF
Rv3812|M.tuberculosis_H37Rv YFTNLMPP-SILRDMSQNFTNVLTTLSNPNIQAVASFDIATTAGTLSTFF
MUL_1640|M.ulcerans_Agy99 GFSNLLPAGSIPAQMTHNLANVLNALTDTSISTTISGTLDPPALVLDANF
MMAR_3494|M.marinum_M DLIDLLPPGAILTQMVQNSFNATNTVVN----------------------
TH_4350|M.thermoresistible__bu PVEQIAAASAAAPMAAKAEVKAEEEVDA----------------------
Mvan_5821|M.vanbaalenii_PYR-1 DALFVKLPQTIAAALKKPVVPAVTSTSTP---------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ----ATPAQLVGAGFTSAAPDTAPVTAVPGGVPSMATAGRGGYGLGAPRY
Mb3842|M.bovis_AF2122/97 GVPLVLTYATLGAPFASLNAIATSAETIEQALLAGNYLGAVGALIDAPAH
Rv3812|M.tuberculosis_H37Rv GVPLVLTYATLGAPFASLNAIATSAETIEQALLAGNYLGAVGALIDAPAH
MUL_1640|M.ulcerans_Agy99 GLPLSILFGVAGAPVAGLDGLATAGTTIGTGVASGNPFMVVGGLIDAPAV
MMAR_3494|M.marinum_M ----SIALAAIGPPIATLDGFATGLTVLGGAVATGNGVGAVGALLDMPAY
TH_4350|M.thermoresistible__bu ---VAAVTSVPGENFRTVNLTTELSTAVENPVAGEPKKSAAVDGVPTTVA
Mvan_5821|M.vanbaalenii_PYR-1 ---ATSALVTLDVPGATPVEVTPVSSTTEQTPETDPAAGAVADEETEVPA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 GVKPTVMPKPAI--------------------------------------
Mb3842|M.bovis_AF2122/97 ALDGFLNSATVLDTPILVPTGLPSPLP---------PTVGITLHLPFDGI
Rv3812|M.tuberculosis_H37Rv ALDGFLNSATVLDTPILVPTGLPSPLP---------PTVGITLHLPFDGI
MUL_1640|M.ulcerans_Agy99 VLDGFLNGETIVDMSLPVTFDVPVLGP---------LNIPVVIHLPFQGL
MMAR_3494|M.marinum_M VLDGFLNGETVVELRVPVSETVTIPLTPLTPPIVVGANTPVLVRMPFGGV
TH_4350|M.thermoresistible__bu TEEATTGATESLDPAAATEGDDGLEDDS-------AKNANGGTDLSDGNK
Mvan_5821|M.vanbaalenii_PYR-1 ESEATPEVEDPTDPVVDETTDDVVDDE-----------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb3842|M.bovis_AF2122/97 LVPPHPVTATISFPGAPVPIPGFPTTVTVFGTPFMGMAPLLINYIPQQLA
Rv3812|M.tuberculosis_H37Rv LVPPHPVTATISFPGAPVPIPGFPTTVTVFGTPFMGMAPLLINYIPQQLA
MUL_1640|M.ulcerans_Agy99 LVPPHPITATVPLEILGVDIP---INLTLGGTQFGGLVPTLVNYTSRHLA
MMAR_3494|M.marinum_M LAQPQPITATIELPGTGSPAP---LDITIPDMQVAGVVPTLLNVIPQRVA
TH_4350|M.thermoresistible__bu ATPATTAGDTSADSGS---------NKAGQSTLRAGVKKATAKASAASST
Mvan_5821|M.vanbaalenii_PYR-1 --IADEIEDTTETEGVDAGAADEDAADDADDAGADGESSAADTSADSDAG
MLBr_01183|M.leprae_Br4923 -------
MAV_1346|M.avium_104 -------
Mb3842|M.bovis_AF2122/97 LAIKPAA
Rv3812|M.tuberculosis_H37Rv LAIKPAA
MUL_1640|M.ulcerans_Agy99 NAITPAA
MMAR_3494|M.marinum_M EAIAPE-
TH_4350|M.thermoresistible__bu GGSDE--
Mvan_5821|M.vanbaalenii_PYR-1 SDTDSE-