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MSHPQAPRCVVAGVDGSQAAINAARWAVPEAASRGIPLRLVHAVPERAASTNDEAALDVEYAQAALHAAS AALHAIEVPVEVEVDIVRGPAEAALVSESLTAAMVCVGSVGIGRVARKLLGSTAEAVTQRAHCPAAIIRT DPDTELSDTSWIAVVVDDSPGNDAVLEHGFREAQLRGAPILAMGVWRWGLGEIAYEQLHRRLDRWVSRYR DVHVQPAAARHGAADFLAKTEEPIQLAVVGSDDAGDVARMVGAVSRRLPQRSGHSVLVVRR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3478 | - | - | 100% (271) | hypothetical protein MMAR_3478 |
| M. marinum M | MMAR_2076 | - | 8e-61 | 47.51% (261) | hypothetical protein MMAR_2076 |
| M. marinum M | MMAR_3481 | - | 6e-41 | 38.52% (270) | hypothetical protein MMAR_3481 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2657c | - | 8e-58 | 45.83% (264) | hypothetical protein Mb2657c |
| M. gilvum PYR-GCK | Mflv_4991 | - | 2e-51 | 45.59% (261) | UspA domain-containing protein |
| M. tuberculosis H37Rv | Rv2624c | - | 8e-58 | 45.83% (264) | hypothetical protein Rv2624c |
| M. leprae Br4923 | MLBr_01390 | - | 1e-06 | 27.27% (143) | hypothetical protein MLBr_01390 |
| M. abscessus ATCC 19977 | MAB_3904 | - | 2e-32 | 33.82% (275) | hypothetical protein MAB_3904 |
| M. avium 104 | MAV_2506 | - | 1e-29 | 31.85% (292) | universal stress protein family protein |
| M. smegmatis MC2 155 | MSMEG_3939 | - | 4e-43 | 40.66% (273) | universal stress protein family protein |
| M. thermoresistible (build 8) | TH_2494 | - | 4e-23 | 30.87% (298) | PUTATIVE putative conserved hypothetical membrane protein |
| M. ulcerans Agy99 | MUL_2424 | - | 2e-32 | 36.67% (270) | hypothetical protein MUL_2424 |
| M. vanbaalenii PYR-1 | Mvan_1387 | - | 2e-56 | 47.53% (263) | UspA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2657c|M.bovis_AF2122/97 MSGRGEPTMKTIIVGIDGSHAAITAALWGVDEAISRAVPLRLVSVIKPTH
Rv2624c|M.tuberculosis_H37Rv MSGRGEPTMKTIIVGIDGSHAAITAALWGVDEAISRAVPLRLVSVIKPTH
Mflv_4991|M.gilvum_PYR-GCK MATAN--SDMPVVAGIDGSAAALGAALWAVDEAAARGATLRLVYVTKPSD
Mvan_1387|M.vanbaalenii_PYR-1 MATAG--TSSPVIAGIDGSATALAAALWAVDEAAGRGAPVHLVYTTKPTD
MSMEG_3939|M.smegmatis_MC2_155 MLEPE--NSAPIVVGIDGSEAGVRAARWAAAEAESRNVPLRLVYATKASH
MMAR_3478|M.marinum_M MSHPQ--APRCVVAGVDGSQAAINAARWAVPEAASRGIPLRLVHAVPERA
MAB_3904|M.abscessus_ATCC_1997 -MNEIRTPGPAVLVGIDGSRSAVRAALWAVDEALHRELPLRLVHVTPQTE
MUL_2424|M.ulcerans_Agy99 ---MSNQAAPAIVVGIDGSRASTHAAVWAVDEAVSRDIPVRLVYIIDPAQ
MAV_2506|M.avium_104 ---MSDPKHRGILVCVDGSAASDAAVAWAAREAAMRGLPITVIHAVAPVV
TH_2494|M.thermoresistible__bu --VSSTAAYEGIVVGVDGSAASADAVRWAARSAALRNLQLTLVHVMTATS
MLBr_01390|M.leprae_Br4923 -----MGAYQTVVVGTDGSDSSLRAVDRAGKIAGSDAKLIIASAYLPQHD
::. *** :. *. . * :
Mb2657c|M.bovis_AF2122/97 PSP-DDYDRDLAHAERSLREAQSAVEAAGKLVKIET--------------
Rv2624c|M.tuberculosis_H37Rv PSP-DDYDRDLAHAERSLREAQSAVEAAGKLVKIET--------------
Mflv_4991|M.gilvum_PYR-GCK RSA-AEYAGDVRHGRQSLREAQVLVQSTGESVNVET--------------
Mvan_1387|M.vanbaalenii_PYR-1 RHA-AEYAEDVRRGHECLHEARSAVEATGKPVTVET--------------
MSMEG_3939|M.smegmatis_MC2_155 PSA-DDYYDDVRRGQDALSAAQIDVNRRYSEVKVET--------------
MMAR_3478|M.marinum_M ASTNDEAALDVEYAQAALHAASAALHAIEVPVEVEV--------------
MAB_3904|M.abscessus_ATCC_1997 FPEFSDE--RSPAG-TAVRHAFRQIGATHKPVKVEA--------------
MUL_2424|M.ulcerans_Agy99 APAGDRDGRQSSAR-AALFDVQRAVEATGQPVKIET--------------
MAV_2506|M.avium_104 VG----WPVGQLYADMPAWQQDGAQQVIDQARKIVI-----ANQGGGTPP
TH_2494|M.thermoresistible__bu IGAPLVWPAGPIPDSLIQWQEDEARQILADSAEIAENAFQEARAAGPGPA
MLBr_01390|M.leprae_Br4923 NARAFDILKDESYKVTGTAPIYEILHDAKERAHAAG--------------
Mb2657c|M.bovis_AF2122/97 ---------DIPRGPAGPVLVEASRD--AEMICVGSVGIGRYASSILGST
Rv2624c|M.tuberculosis_H37Rv ---------DIPRGPAGPVLVEASRD--AEMICVGSVGIGRYASSILGST
Mflv_4991|M.gilvum_PYR-GCK ---------EIVDGPPAQALVALSEH--AQMVCVGSVGIGRYARSILGST
Mvan_1387|M.vanbaalenii_PYR-1 ---------TVVDGPAAQALISLSEQ--AQMVCVGSVGIGRYARSILGST
MSMEG_3939|M.smegmatis_MC2_155 ---------ALVDGPPGRALIDESDR--AAMLCVGSVGIGRYAESILGSI
MMAR_3478|M.marinum_M ---------DIVRGPAEAALVSESLT--AAMVCVGSVGIGRVARKLLGST
MAB_3904|M.abscessus_ATCC_1997 ---------EIRHGRVADVLLDASRS--AVMLCVGAIGISGADTRKVGST
MUL_2424|M.ulcerans_Agy99 ---------EILWGRPLTKLLEESRT--AVMVCVGSIGLN-HARRGEGSV
MAV_2506|M.avium_104 -----EMRTEIIYSAVTPTLIDASRD--AWMIVAGSQGLGALGRLLLGSV
TH_2494|M.thermoresistible__bu GDDAVRVVTGVVRAAPVPTLVDASKQ--AKLVAVGSRGQGPLRRVLLGSV
MLBr_01390|M.leprae_Br4923 ---AKNVEERPVVGAPVDALVNLAEKTNADLLVVGNVGLSTIAGRLLGSV
. *: : * :: .* * . **
Mb2657c|M.bovis_AF2122/97 ATELAEKAHCPVAVMRS-KVDQPASDINWIVVRMTDAPDNEAVLEYAARE
Rv2624c|M.tuberculosis_H37Rv ATELAEKAHCPVAVMRS-KVDQPASDINWIVVRMTDAPDNEAVLEYAARE
Mflv_4991|M.gilvum_PYR-GCK AADVAAAARCPVAVIRP-ESRVGVDTPNWIIVAVNDRPHNGAVVEHALQE
Mvan_1387|M.vanbaalenii_PYR-1 AAEVAERAHCPVAVIRP-HPHAGEHGFHWIVVAVTEQPQNAEVVEHALRE
MSMEG_3939|M.smegmatis_MC2_155 ALAVAEGAACPVAVIRA-QE--DDSAVHWIAAGN---PADEHVVESAMAE
MMAR_3478|M.marinum_M AEAVTQRAHCPAAIIRT-DPDTELSDTSWIAVVVDDSPGNDAVLEHGFRE
MAB_3904|M.abscessus_ATCC_1997 AAEVLRSVRCPVAVIRD-DP-SSLRGTSAVVVEIDESHESVTPLELAAHE
MUL_2424|M.ulcerans_Agy99 AGTLAGSALCPVAVIQS-PA-GAAG--APKVGEVVAEVDNGSVLRHAFEE
MAV_2506|M.avium_104 TAALLAHAHCPVAVVHT-DDHAARAADAPVLVGTDGSPASEAAIALAFDE
TH_2494|M.thermoresistible__bu SSGLVHHAHCPVAVIREGTPHTPDFAKRPVLVGIDGSESAQRATAVAFEE
MLBr_01390|M.leprae_Br4923 PANVSRRAKIDVLIVHTTH-------------------------------
. : . . :::
Mb2657c|M.bovis_AF2122/97 AKLRQAPILALGGRP-------------EELREIPDGEFERRVQDWHHRH
Rv2624c|M.tuberculosis_H37Rv AKLRQAPILALGGRP-------------EELREIPDGEFERRVQDWHHRH
Mflv_4991|M.gilvum_PYR-GCK AALRHAAVLVLG----------------DSRTAASAEVLEQRIRPWHERY
Mvan_1387|M.vanbaalenii_PYR-1 AALRHVPVLALG----------------DGRTEDSADALERHLRSWRERY
MSMEG_3939|M.smegmatis_MC2_155 ARLRQAPVLVLG----------------DRR---EGDAFIYQVKSIQLRN
MMAR_3478|M.marinum_M AQLRGAPILAMGVWR-------------WGLGEIAYEQLHRRLDRWVSRY
MAB_3904|M.abscessus_ATCC_1997 ARLRAAPLRVLLRHRPISLSGQRVATLTRVDRRVAAVHVERRLAPLRVRY
MUL_2424|M.ulcerans_Agy99 ARLRNVPLRAISSRVATDHGSE-------DGNRLATAQLTRRLTRWTRLY
MAV_2506|M.avium_104 ASRRGVGVVALHAWSDVGVFPILG-MDWRDSEAKGEELLAERLAGWQEQY
TH_2494|M.thermoresistible__bu ASFRGVDLIALHAWSDADIADIPT-LELSAVQQSAERVLSERLAGFRERY
MLBr_01390|M.leprae_Br4923 --------------------------------------------------
Mb2657c|M.bovis_AF2122/97 PDVRVYPITTHTGIARFLADHDERVQLAVIGGGEAGQLARLVGPSGH---
Rv2624c|M.tuberculosis_H37Rv PDVRVYPITTHTGIARFLADHDERVQLAVIGGGEAGQLARLVGPSGH---
Mflv_4991|M.gilvum_PYR-GCK PQVHVYPIANRADVAHFLRKHDEPVLLAVLGDDEADEVAQIVG-HGR---
Mvan_1387|M.vanbaalenii_PYR-1 PDVHIYPIAGSADVTHFLKKHDEPVMLTVIGSDEAGEVAKIIG-HGH---
MSMEG_3939|M.smegmatis_MC2_155 PDLHIYPITDRNDVAGFLRRHDEPVQLAVIGESEVAELPRILGPHGRHMF
MMAR_3478|M.marinum_M RDVHVQPAAARHGAADFLAKTEEPIQLAVVGSDDAGDVARMVGAVSR---
MAB_3904|M.abscessus_ATCC_1997 PDLDIRALDPVGGTLDYLERHGHTVQLVVVGAGDAAHVQELVGPNGC---
MUL_2424|M.ulcerans_Agy99 PDVRVESAIIAGHACRYMAANAKPDELYVTDS-HAAQVCSVYGAG-----
MAV_2506|M.avium_104 PDVHVKRLVVCDKPSRWLVAEAERAQLVVVGSHGRGGFPGMLLGSVSS--
TH_2494|M.thermoresistible__bu PDVSVHRRIVGSEPARHLVEASEDAQLVVVGSRGRGGFTGMLLGSVSR--
MLBr_01390|M.leprae_Br4923 --------------------------------------------------
Mb2657c|M.bovis_AF2122/97 PVFRHAECSVLVVRR----
Rv2624c|M.tuberculosis_H37Rv PVFRHAECSVLVVRR----
Mflv_4991|M.gilvum_PYR-GCK SALRHGASSALVVRS----
Mvan_1387|M.vanbaalenii_PYR-1 SLLRRGTSSALVVRS----
MSMEG_3939|M.smegmatis_MC2_155 HLFEGTTSSVLVARYD---
MMAR_3478|M.marinum_M RLPQRSGHSVLVVRR----
MAB_3904|M.abscessus_ATCC_1997 GVLGRTHCSVLIAERQRLL
MUL_2424|M.ulcerans_Agy99 -------CSVLTVRSGNL-
MAV_2506|M.avium_104 HVAQSATAPVIVVRGR---
TH_2494|M.thermoresistible__bu AVVNAVTTPVIVAR-----
MLBr_01390|M.leprae_Br4923 -------------------