For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
DPMSHDPAAGDIGSQLVDIGTQGISAGTTAAMTVLTGLIPAGAEEVSAQAVLAFAQEAATMLASNVAAQE ELMRTGTALSDIARMYGDADDVAADALTFRGAAMSNPAAAGSSGFATGAGLRAGAFATEAGPAAQPLVSQ LIGSQSSPMAAAAANAGSSAMSGAAPMGSGMGAGSSAGGASKPGLVSATGPADEEEERKDSAAAGEQNGL ADVGQREDASGSHPVERLM*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2894 | - | - | 100% (230) | PE family protein |
| M. marinum M | MMAR_5286 | - | 5e-21 | 51.35% (111) | PE family protein, PE34 |
| M. marinum M | MMAR_0185 | - | 2e-18 | 50.00% (98) | PE family protein, PE35 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3902 | PE35 | 1e-23 | 54.74% (95) | PE family-like protein |
| M. gilvum PYR-GCK | Mflv_0769 | - | 2e-13 | 40.21% (97) | PE-like protein |
| M. tuberculosis H37Rv | Rv3872 | PE35 | 1e-23 | 54.74% (95) | PE family-related protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1895c | - | 2e-05 | 23.94% (188) | hypothetical protein MAB_1895c |
| M. avium 104 | MAV_5288 | - | 3e-05 | 26.83% (205) | hypothetical protein MAV_5288 |
| M. smegmatis MC2 155 | MSMEG_0063 | - | 3e-18 | 47.47% (99) | PE family protein |
| M. thermoresistible (build 8) | TH_3343 | - | 1e-15 | 51.16% (86) | PUTATIVE PE domain protein |
| M. ulcerans Agy99 | MUL_4359 | - | 3e-21 | 51.35% (111) | PE family protein |
| M. vanbaalenii PYR-1 | Mvan_0076 | - | 3e-14 | 40.82% (98) | PE-like protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0769|M.gilvum_PYR-GCK ------------------MQPLNHNPAAAGIGGQVTANGARGLGVGTA-A
Mvan_0076|M.vanbaalenii_PYR-1 ------------------MQPLSHNPGAIGVGGQVTANGARGLATGTA-A
MSMEG_0063|M.smegmatis_MC2_155 ------------------MQPMTHNPGAEAVAAQVIANAARGLAGGTT-A
TH_3343|M.thermoresistible__bu ----------------------------VGIGSQVIANGTRGLAVGTA-A
Mb3902|M.bovis_AF2122/97 ------------------MEKMSHDPIAADIGTQVSDNALHGVTAGST-A
Rv3872|M.tuberculosis_H37Rv ------------------MEKMSHDPIAADIGTQVSDNALHGVTAGST-A
MUL_4359|M.ulcerans_Agy99 ------------------MQSMSIDPVAADIGAQLAEGAFRGLQAGAT-A
MMAR_2894|M.marinum_M ------------------MDPMSHDPAAGDIGSQLVDIGTQGISAGTTAA
MAV_5288|M.avium_104 ------MAPSGLGLGPGGQPNLAQSFASGLATGQATGPGGQAFSANALQA
MAB_1895c|M.abscessus_ATCC_199 MTGEEDGWTRGNREREIVYANQRQHGANIDGGTESVGVPTEDFNSWTHAK
: . . :
Mflv_0769|M.gilvum_PYR-GCK TAEVSALAPAG-VDEIS---------------------------------
Mvan_0076|M.vanbaalenii_PYR-1 TSAVSALAPAG-ADEVS---------------------------------
MSMEG_0063|M.smegmatis_MC2_155 SAAVTALVPAG-ADEVS---------------------------------
TH_3343|M.thermoresistible__bu SAEVTALVPAG-ADEVS---------------------------------
Mb3902|M.bovis_AF2122/97 LTSVTGLVPAG-ADEVS---------------------------------
Rv3872|M.tuberculosis_H37Rv LTSVTGLVPAG-ADEVS---------------------------------
MUL_4359|M.ulcerans_Agy99 ATSITSVRPAG-ADEVS---------------------------------
MMAR_2894|M.marinum_M MTVLTGLIPAG-AEEVS---------------------------------
MAV_5288|M.avium_104 METGAPQTPAG-TPPVAP--------------------------------
MAB_1895c|M.abscessus_ATCC_199 IKAASDAFDSGKAIEVSADWEKLATGFSKALDDFKRSFDVAVGAQWTGEG
: :* . ::
Mflv_0769|M.gilvum_PYR-GCK ----------AVAALSFASEGIQTLGIN-AMAQQEIARAGATVIEASVAY
Mvan_0076|M.vanbaalenii_PYR-1 ----------AAAAVTFAAEGIQTLGIN-ALAQEEIARAGASIIEAAGAY
MSMEG_0063|M.smegmatis_MC2_155 ----------ALAAVAFASEGVEALAAN-AFAQEELTRAGAAFAEIAGIY
TH_3343|M.thermoresistible__bu ----------AQAAAAFAKEGMEALALN-TFAQEELARAGAAVVQIAGIY
Mb3902|M.bovis_AF2122/97 ----------AQAATAFTSEGIQLLASN-ASAQDQLHRAGEAVQDVARTY
Rv3872|M.tuberculosis_H37Rv ----------AQAATAFTSEGIQLLASN-ASAQDQLHRAGEAVQDVARTY
MUL_4359|M.ulcerans_Agy99 ----------TQAMLAFTKHAGQMLALN-QAAQEELRRAGEAVNAIARMY
MMAR_2894|M.marinum_M ----------AQAVLAFAQEAATMLASN-VAAQEELMRTGTALSDIARMY
MAV_5288|M.avium_104 ---------TVPSAGAFIAATPPVDAPP-AAAPAPSAAGGAAPVAPAVMT
MAB_1895c|M.abscessus_ATCC_199 AEAAKQGISDYKSHAEKVSDGLSLMATKPAEVETAMTQIKGLMPEVVQVQ
: . .
Mflv_0769|M.gilvum_PYR-GCK EATDAANGAKLI--------------------------------------
Mvan_0076|M.vanbaalenii_PYR-1 QAVDASNATTLI--------------------------------------
MSMEG_0063|M.smegmatis_MC2_155 NAVDAANAATM---------------------------------------
TH_3343|M.thermoresistible__bu DAVDAANAGTLA--------------------------------------
Mb3902|M.bovis_AF2122/97 SQIDDGAAG-----------------------------VFA---------
Rv3872|M.tuberculosis_H37Rv SQIDDGAAG-----------------------------VFAE--------
MUL_4359|M.ulcerans_Agy99 ADTDVAVARNLIDVGWRSG------------------SALANV-------
MMAR_2894|M.marinum_M GDADDVAADALTFRGAAMSNPAAAGSSGFATGAGLRAGAFATEAGPAAQP
MAV_5288|M.avium_104 GGSWSSAATGGPSVPSGSLPAYGSDLRPPVLAAPSVPSAPTGPVSGAPVA
MAB_1895c|M.abscessus_ATCC_199 QPKEHTQAAYEQYYAQQALADQKQDEARMIMRNVWSPVSQQAGSGLPALP
.
Mflv_0769|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0076|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0063|M.smegmatis_MC2_155 --------------------------------------------------
TH_3343|M.thermoresistible__bu --------------------------------------------------
Mb3902|M.bovis_AF2122/97 --------------------------------------------------
Rv3872|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4359|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2894|M.marinum_M LVSQLIGSQSSPMAAAAANAGSSAMSGAAPMGSGMGAGSSAGGASKPGLV
MAV_5288|M.avium_104 PSPASSPSAGGTLVSPVERSAASAAAGQAGAGSSTLANASAVSAAAGATA
MAB_1895c|M.abscessus_ATCC_199 PAPQFADAASMPVNAASSLSGLGSGKDIKPDQVKPIDEASVRAAAAAALA
Mflv_0769|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0076|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0063|M.smegmatis_MC2_155 --------------------------------------------------
TH_3343|M.thermoresistible__bu --------------------------------------------------
Mb3902|M.bovis_AF2122/97 --------------------------------------------------
Rv3872|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4359|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2894|M.marinum_M SATGPADEEEERKDSAAAGEQNGLADVGQREDASGSHPVERLM-------
MAV_5288|M.avium_104 GAASSRAAEQQRLQRLVDAVARQEPRLSWAAGLRDDGITTLLVTDLASGW
MAB_1895c|M.abscessus_ATCC_199 DPSQASASGASGAGGAAAAAGAAGGASGAGAGGPAAAAAAAGAG----GG
Mflv_0769|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0076|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0063|M.smegmatis_MC2_155 --------------------------------------------------
TH_3343|M.thermoresistible__bu --------------------------------------------------
Mb3902|M.bovis_AF2122/97 --------------------------------------------------
Rv3872|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4359|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2894|M.marinum_M --------------------------------------------------
MAV_5288|M.avium_104 IPPHVRLPAHVTLLEPAARRHDANVVDLLGAVTVAAAHHANTYVAEPGSD
MAB_1895c|M.abscessus_ATCC_199 TSTRPSSGGNTTATGPNTGSVPGTYGIGRWGKPTTNKDEKKDEKSDLGAL
Mflv_0769|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0076|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0063|M.smegmatis_MC2_155 --------------------------------------------------
TH_3343|M.thermoresistible__bu --------------------------------------------------
Mb3902|M.bovis_AF2122/97 --------------------------------------------------
Rv3872|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4359|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2894|M.marinum_M --------------------------------------------------
MAV_5288|M.avium_104 EPTLSGDRPARSAAPQIDELGPTLVDAVRRRDGLPRIAQAVAAPAVRKTG
MAB_1895c|M.abscessus_ATCC_199 AAGPIIAGSYTAGAGMGLSAAPTPSPMSGMGIAQPPTMMTAGAAGQHRQE
Mflv_0769|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0076|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0063|M.smegmatis_MC2_155 --------------------------------------------------
TH_3343|M.thermoresistible__bu --------------------------------------------------
Mb3902|M.bovis_AF2122/97 --------------------------------------------------
Rv3872|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4359|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2894|M.marinum_M --------------------------------------------------
MAV_5288|M.avium_104 VLESEIRMLRECTAEIQHAVLTAYPHHDPAAVGDWMLLAAIQALIDGHEY
MAB_1895c|M.abscessus_ATCC_199 DEDQHFTPEFLVSLDNGNELVGPLPKVSPAVIGVWNEEHVEYQNPHASPY
Mflv_0769|M.gilvum_PYR-GCK ------------------
Mvan_0076|M.vanbaalenii_PYR-1 ------------------
MSMEG_0063|M.smegmatis_MC2_155 ------------------
TH_3343|M.thermoresistible__bu ------------------
Mb3902|M.bovis_AF2122/97 ------------------
Rv3872|M.tuberculosis_H37Rv ------------------
MUL_4359|M.ulcerans_Agy99 ------------------
MMAR_2894|M.marinum_M ------------------
MAV_5288|M.avium_104 LAHYHLAWFQAINHRAGS
MAB_1895c|M.abscessus_ATCC_199 DPKPYDGED---------