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M. marinum M MMAR_1375 (atsD_1)

annotation: arylsulfatase AtsD_1
coordinates: 1672942 - 1675245
length: 767

MAHDATAQEPGENLDRTRLPLPDTPTGGHSGKTVAESKMATITPIRPPQGAPNVVIVLLDDVGFGATATF
GGPVETPAGDALAQEGLRYNRFHTTALCSPTRAALLTGRNHHVVNTGTITEFATGYDGYNCIIPKSAATV
AETLRQNGYSTAAFGKWHNTPVWEVSAAGPFDRWPTGMGFEEFYGFMGGEAHQYNPGLYHGTTPIERPED
AEDYHLSTDLADRMIEWVHRQQVMAPDRPFFAYWAPGATHAPHHVAPEWSDPFRGRFDQGWDVLREEIFA
RQKRLGVIPADAELTERHESLPAWDSLPEQRQRIASRLMEVYAGFLAHTDHEVGRIMDALKEIDVWDNTL
FIYIIGDNGAAPGGGLGGVFNEMVTLNGLQEDVDVVLSKMDEIGGPRASNEYPVGFAWAMCTPFQFTKQF
ASHFGGTRNPMIVSWPARITDRGGLRSQFHHVVDIAPTILEAAGIPAPEIVNGVAQKPHDGISLMYTFDD
AEAADRRRTQYFEIGGLRGIYHEDWMACTYHGRILWRPGALPAFSDDRWELYDLSRDYSQAVDLSAQFPD
KLEQLKALFDAEGVKNNVFPLDDRGRLARALEPRPTILGSRTSISFRQGATRIPEDIIRSAFNRSYSITA
VIDTPGGSAVEGVLLAAGGYFAGLSLYVQHGIPTFTYNYFGSTYTTVAATEALPAGKATVAMEFDYDGGG
LGKGGLVRLLLNGRDVGQSRIERTVPLGFSADEGVDIGMDCGTPAADTYEGTFVFNATIEQVTIQLR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_1375atsD_1-100% (767)arylsulfatase AtsD_1
M. marinum MMMAR_2840atsD_20.055.61% (748) arylsulfatase AtsD_2
M. marinum MMMAR_4950atsD0.053.20% (765) arylsulfatase AtsD

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0682atsD0.051.05% (762) arylsulfatase AtsD
M. gilvum PYR-GCKMflv_5039-1e-15239.51% (734) sulfatase
M. tuberculosis H37RvRv0663atsD0.050.92% (762) arylsulfatase AtsD
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4307-1e-13937.11% (733) arylsulfatase AtsA
M. avium 104MAV_4461-1e-15039.22% (747) arylsulfatase
M. smegmatis MC2 155MSMEG_1451-1e-14938.51% (740) arylsulfatase
M. thermoresistible (build 8)TH_0315-1e-15138.46% (741) arylsulfatase
M. ulcerans Agy99MUL_2500atsD_10.098.31% (711) arylsulfatase AtsD_1
M. vanbaalenii PYR-1Mvan_4467-0.052.16% (763) sulfatase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_5039|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_1451|M.smegmatis_MC2_155      --------------------------------------------------
MAV_4461|M.avium_104                --------------------------------------------------
TH_0315|M.thermoresistible__bu      --------------------------------------------------
MAB_4307|M.abscessus_ATCC_1997      MHIPGDDAPEPEQNAERGRLTRRSMLGGIAAAGMGVAAASALVAGCDDDS
MMAR_1375|M.marinum_M               -----------------------------------------MAHDATAQE
MUL_2500|M.ulcerans_Agy99           --------------------------------------------------
Mb0682|M.bovis_AF2122/97            --------------------------------------------------
Rv0663|M.tuberculosis_H37Rv         --------------------------------------------------
Mvan_4467|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mflv_5039|M.gilvum_PYR-GCK          ------------MTTEFNGKIALDIRDSEPDWGPFAAPTAQPEAPNVLYL
MSMEG_1451|M.smegmatis_MC2_155      ------------MAAEFNGKIELDIRDSEPDWGPFAAPTAAEGAPNVLYV
MAV_4461|M.avium_104                ------MVAGSGQSAEFSGRVELDIRDSEPDWGPYAAPTAPPNAPNILYL
TH_0315|M.thermoresistible__bu      -------------MADFGGKIELDIRDSEPDWGPFAAPTAPEGAPNILYV
MAB_4307|M.abscessus_ATCC_1997      SSRTDRSSAAEEANAGFNGKIELDVRDSKPDWTPYELKHAPDGAPNVLVV
MMAR_1375|M.marinum_M               PGENLDRTRLPLPDTPTGGHSGKTVAES--KMATITPIRPPQGAPNVVIV
MUL_2500|M.ulcerans_Agy99           -------------------------------------------------M
Mb0682|M.bovis_AF2122/97            --MPQPRTHLPIPSAARTGLITYDAKDPDSTYPPIEQLRPPAGAPNVLLI
Rv0663|M.tuberculosis_H37Rv         --MPQPRTHLPIPSAARTGLITYDAKDPDSTYPPIEQLRPPAGAPNVLLI
Mvan_4467|M.vanbaalenii_PYR-1       ----MRRDILPIPDPQHVGLTTYDAKDPDTTYPPITPLRPPQGAPNVLIV
                                                                                     :

Mflv_5039|M.gilvum_PYR-GCK          VWDDIGIATWDCFGGLVDMPAMSRIAERGVRLSQFHTTALCSPTRASLLT
MSMEG_1451|M.smegmatis_MC2_155      VWDDIGIATWDCFGGLVEMPAMSRIAEHGVRLSQFHTTALCSPTRAALLT
MAV_4461|M.avium_104                VWDDTGIATWDCFGGLVEMPAMSRIAERGVRLSQFHTTALCSPTRAALLT
TH_0315|M.thermoresistible__bu      VWDDVGIGTWDCFGGLVEMPTMSRIAEQGVRLSQFHTTALCSPTRAALLT
MAB_4307|M.abscessus_ATCC_1997      LFDDTGMATWSPYGGRVNMPTLQRLADNGLTYSQWHTTALCSPTRSCLLT
MMAR_1375|M.marinum_M               LLDDVGFGATATFGGPVETPAGDALAQEGLRYNRFHTTALCSPTRAALLT
MUL_2500|M.ulcerans_Agy99           LLDDVGFGATATFGGPVETPAGDALAQEGLRYNRFHTTALCSPTRAALLT
Mb0682|M.bovis_AF2122/97            LLDDVGFGASSAFGGPCRTSTAELLAGNGLRYNRFHTTALCSPTRQALLT
Rv0663|M.tuberculosis_H37Rv         LLDDVGFGASSAFGGPCRTSTAELLAGNGLRYNRFHTTALCSPTRQALLT
Mvan_4467|M.vanbaalenii_PYR-1       LLDDVGFGASSAFGGPCATPTAERLAANGLKLNRFHTTALCSPTRQALLT
                                    : ** *:.:   :**    .: . :* .*:  .::********** .***

Mflv_5039|M.gilvum_PYR-GCK          GRNATTVGMATIEEFTDGFPNCNGRIPFDTALLSEVLSENGYNTYCIGKW
MSMEG_1451|M.smegmatis_MC2_155      GRNPTTVGMATIEEFTDGFPNCSGRIPFETALLPEVLAENGYNTYCIGKW
MAV_4461|M.avium_104                GRNATTVGMATIEEFTEGFPNANGRIPFDTALLSEALAEHGYNTYCVGKW
TH_0315|M.thermoresistible__bu      GRNPTTVGMATIEEFTDGFPNCSGRIPVDTGLISEVLAEHGWNTYCVGKW
MAB_4307|M.abscessus_ATCC_1997      GRNHHVNRFASITEGSDGYPGAAGRLPAQCATIGQVLQDNGYSTFWVGKN
MMAR_1375|M.marinum_M               GRNHHVVNTGTITEFATGYDGYNCIIPKSAATVAETLRQNGYSTAAFGKW
MUL_2500|M.ulcerans_Agy99           GRNHHVVNTGTITEFATGYDGYNCIIPKSAATVAETLRQNGYSTAAFGKW
Mb0682|M.bovis_AF2122/97            GRNHHSAGMGGITEIATGAPGYSSVLPNTMSPIARTLKLNGYNTAQFGKC
Rv0663|M.tuberculosis_H37Rv         GRNHHSAGMGGITEIATGAPGYSSVLPNTMSPIARTLKLNGYNTAQFGKC
Mvan_4467|M.vanbaalenii_PYR-1       GRNHHSVGMGGVTEIATSAPGYSSIRPKDKAPVAETLRLNGYSTSQFGKC
                                    ***      . : * : .  .     *   . : ..*  :*:.*  .** 

Mflv_5039|M.gilvum_PYR-GCK          HLTPLEESNLAATKRHWPLS-RGFERFYGFMGGETDQWYPDLMYDNHPVA
MSMEG_1451|M.smegmatis_MC2_155      HLTPLEESNLASTKRHWPCS-RGFERFYGFMGGETDQWYPDLTYDNHPVD
MAV_4461|M.avium_104                HLTPLEESNMASTKRHWPTS-RGFERFYGFLGGETDQWYPDLVYDNHPVS
TH_0315|M.thermoresistible__bu      HLTPLEESNMAATKRHWPVS-RGFERFYGFLGGETDQWYPDLVHDNHPVA
MAB_4307|M.abscessus_ATCC_1997      HNVPQEDVSCGGSKSEWPLQ-KGFDRYYGFLGGETNNWYPDLVEDNRFIE
MMAR_1375|M.marinum_M               HNTPVWEVSAAGPFDRWPTG-MGFEEFYGFMGGEAHQYNPGLYHGTTPIE
MUL_2500|M.ulcerans_Agy99           HNTPVWEVSAAGPFDRWPTG-MGLEEFYGFMGGEAHQYNPGLYHGTTPIE
Mb0682|M.bovis_AF2122/97            HEVPVWQTSPVGPFDAWPSGGGGFEYFYGFIGGEANQWYPSLYEGTTPVE
Rv0663|M.tuberculosis_H37Rv         HEVPVWQTSPVGPFDAWPSGGGGFEYFYGFIGGEANQWYPSLYEGTTPVE
Mvan_4467|M.vanbaalenii_PYR-1       HEVPVWEVSPVGPFGQWPTG-SGFEHFYGFIGGEANQYYPGLYEGTKPVE
                                    * .*  : .  ..   **    *:: :***:***:.:: *.*  ..  : 

Mflv_5039|M.gilvum_PYR-GCK          PPATPEEGYHLSKDLADKTIEFIRDSKVIAPDKPWFSYVCPGAGHAPHHV
MSMEG_1451|M.smegmatis_MC2_155      PPATPEEGYHLSKDLADKTIEFIRDAKVVASDKPWFTYLCPGAGHAPHHV
MAV_4461|M.avium_104                PPATPEDGYHLSKDLADKTIEFIRDAKVIAPEKPWFSYVCPGAGHAPHHV
TH_0315|M.thermoresistible__bu      PPATPEDGYHLSKDLADKTIEFIRDAKVIAPDKPWFTYLCPGAGHAPHHA
MAB_4307|M.abscessus_ATCC_1997      QPTSPEQGYHLSKDLADQALRMLRDQRNTNPSKPWYMWFCPGANHAPHHS
MMAR_1375|M.marinum_M               RPEDAED-YHLSTDLADRMIEWVHRQQVMAPDRPFFAYWAPGATHAPHHV
MUL_2500|M.ulcerans_Agy99           RPEDAED-YHLSTDLADRMIEWVHRQRAMAPDRPFFAYWAPGATHAPHHV
Mb0682|M.bovis_AF2122/97            VNRTPEEGYHFMADMTDKALGWIGQQKALAPDRPFFVYFAPGATHAPHHV
Rv0663|M.tuberculosis_H37Rv         VNRTPEEGYHFMADMTDKALGWIGQQKALAPDRPFFVYFAPGATHAPHHV
Mvan_4467|M.vanbaalenii_PYR-1       PEKTPEQGYTLTEDLADRAITWVRQQQALTPDKPFFMYFAPGATHAPHHV
                                        .*: * :  *::*: :  :   :   ..:*:: : .*** ***** 

Mflv_5039|M.gilvum_PYR-GCK          FKEWADRYAGRFDMGYEAYREIVLENQKRLGLVPPDTELSAVNPYLDVKG
MSMEG_1451|M.smegmatis_MC2_155      FKEWADRYKGRFDMGYERYREIVLENQKRMGLVPPDTELSPVNPYSEVTG
MAV_4461|M.avium_104                FKEWADRYAGRFDMGYERYREVVLERQKAMGIVPSDTELSPVNPYLDVTG
TH_0315|M.thermoresistible__bu      PRDWADRYAGRFDMGYERYREVVLENQKKLGIVPPDTELPPINPYQDVKG
MAB_4307|M.abscessus_ATCC_1997      PAEYADKYRGKFDDGYEAYREWVLARMIDKGIMPRETKLTPINPLPNDVA
MMAR_1375|M.marinum_M               APEWSDPFRGRFDQGWDVLREEIFARQKRLGVIPADAELTER--------
MUL_2500|M.ulcerans_Agy99           APEWSDPFRGRFDQGWDVLREEIFARQKRLGVIPADAELTER--------
Mb0682|M.bovis_AF2122/97            PREWADKYRGRFDVGWDALREETFARQKELGVIPADCQLTAR--------
Rv0663|M.tuberculosis_H37Rv         PREWADKYRGRFDVGWDALREETFARQKELGVIPADCQLTAR--------
Mvan_4467|M.vanbaalenii_PYR-1       PKQWSDKYRGKFDDGWDVLRESMLDNQKALGVVPEDAQLTAR--------
                                      :::* : *:** *::  **  : .    *::* : :*.          

Mflv_5039|M.gilvum_PYR-GCK          PDGQDWPAQDTVRPWDSLSEDEKRLFARMAEVFAGFLSYTDAQIGRVLDY
MSMEG_1451|M.smegmatis_MC2_155      PDGQPWPAQDTVRPWDSLSDDEKALFCRMAEVFAGFLSYTDAQIGRVLDY
MAV_4461|M.avium_104                PSGEPWPLQDTVRPWDSLNDEEKKLFARMAEVFAGFLSYTDAQIGRILDY
TH_0315|M.thermoresistible__bu      PHGEPWPLQDTVRPWDSLSDAEKRLFCRMAEVFAGFLSYTDHQIGRVLDY
MAB_4307|M.abscessus_ATCC_1997      VEA------DSVRPWNTLNPDEKRLFSRMAEVFAGFSEYTDAQVGRVIDY
MMAR_1375|M.marinum_M               --------HESLPAWDSLPEQRQRIASRLMEVYAGFLAHTDHEVGRIMDA
MUL_2500|M.ulcerans_Agy99           --------HESLPAWDSLPEQRQRIASRLMEVYAGFLAHTDHEVGRIMDA
Mb0682|M.bovis_AF2122/97            --------HAEIPAWDDMPEDLKPVLCRQMEVYAGFLEYTDHHVGRLVDG
Rv0663|M.tuberculosis_H37Rv         --------HAEIPAWDDMPEDLKPVLCRQMEVYAGFLEYTDHHVGRLVDG
Mvan_4467|M.vanbaalenii_PYR-1       --------HDEIPAWDDMPDVLKPVLARQMEIYAGFLEQTDHEIGRLVDA
                                               : .*: :    : : .*  *::***   ** .:**::* 

Mflv_5039|M.gilvum_PYR-GCK          LEESGQLDNTVIVVIS-DNGASGEGGPNGSVNEVKFFNGYI--DSAEESL
MSMEG_1451|M.smegmatis_MC2_155      LEESGQIDNTIIVVIS-DNGASGEGGPNGSVNETKFFNGYI--DTAEEGL
MAV_4461|M.avium_104                LEESGQLDDTIIVVIS-DNGASGEGGPNGSVNEGKFFNGYI--DTVEESM
TH_0315|M.thermoresistible__bu      LEESDQLDNTLIVVLS-DNGASGEGGPDGSVNEVKFFNGYV--DTVEESM
MAB_4307|M.abscessus_ATCC_1997      LEQTGQLDNTVVFYCA-DNGASGEGSPNGSVNENKFFNGYP--DDLAENM
MMAR_1375|M.marinum_M               LKEIDVWDNTLFIYIIGDNGAAPGGGLGGVFNEMVTLNGLQ--EDVDVVL
MUL_2500|M.ulcerans_Agy99           LKEIGVWDNTLFIYIIGDNGAAPGGGHGGVFNEMVTLNGLQ--EDVDVVL
Mb0682|M.bovis_AF2122/97            LQRLGVLDDTLVFYIIGDNGASAEGTINGTYNEMLNFNGLADIETPRFMT
Rv0663|M.tuberculosis_H37Rv         LQRLGVLDDTLVFYIIDDNGASAEGTINGTYNEMLNFNGLADIETPRFMT
Mvan_4467|M.vanbaalenii_PYR-1       IDDLGALDNTLIYYIIGDNGASAEGTPNGCFNEMCTLNGLAGIETPEFLL
                                    :.  .  *:*:.     ****:  *  .*  **   :**    :      

Mflv_5039|M.gilvum_PYR-GCK          KVFDELGGPQTYNHYPIGWAMAFNTPYKLFKRYASHEGGIADTAIISWPK
MSMEG_1451|M.smegmatis_MC2_155      KFIDKLGGPQTYNHYPIGWAMAFNTPYKLFKRYASHEGGIADPAIISWPK
MAV_4461|M.avium_104                KLFDQLGGPQTYNHYPIGWAMAFNTPYKLYKRYASHEGGIADTAIISWPN
TH_0315|M.thermoresistible__bu      RFYDQLGGPQTYNHYPTGWAMAFNTPYKLFKRYASHEGGIADPAIISWPN
MAB_4307|M.abscessus_ATCC_1997      KYIDRLGTPDTYNHYPTGWAVAFSTPFQMFKRYSQFSGGTCDPLVIHWPK
MMAR_1375|M.marinum_M               SKMDEIGGPRASNEYPVGFAWAMCTPFQFTKQFASHFGGTRNPMIVSWPA
MUL_2500|M.ulcerans_Agy99           SKMDEIGGPRASNEYPVGFAWAMCTPFQFTKQFASHFGGTRNPMIVSWPA
Mb0682|M.bovis_AF2122/97            DRLDKFGGPESYNHYSVGWAHAMDTPYQWTKQVASHWGGTRNGTIVHWPN
Rv0663|M.tuberculosis_H37Rv         DRLDKFGGPESYNHYSVGWAHAMDTPYQWTKQVASHWGGTRNGTIVHWPN
Mvan_4467|M.vanbaalenii_PYR-1       SKIDDFGTPDAYNHYAVGWAHALCGPYQWTKQVASHWGGTRNGTIVHWPN
                                       * :* * : *.*. *:* *:  *::  *: :.. **  :  :: ** 

Mflv_5039|M.gilvum_PYR-GCK          GIAAHGEIRDNYVNVADITPTVYDLLDITPPATVRGVAQKPLDGVSFKVA
MSMEG_1451|M.smegmatis_MC2_155      GIAARGEVRDNYVNVCDVTPTVYDMLGITPPATVRGVPQKPLDGVSFKAA
MAV_4461|M.avium_104                GIAAHGEIRDNYVNVCDITPTVYDLLGMSPPETVKGIAQKPLDGVSFKAA
TH_0315|M.thermoresistible__bu      GITARDAVCDRYINVVDVTPTVYELIGLTPPDTVRGVRQRPLEGVSFRAA
MAB_4307|M.abscessus_ATCC_1997      GIKAKGEVRHQYHHVTDIVPTILDVAGLTMPETYRGVDQFPVNGVSMRYT
MMAR_1375|M.marinum_M               RITDRGGLRSQFHHVVDIAPTILEAAGIPAPEIVNGVAQKPHDGISLMYT
MUL_2500|M.ulcerans_Agy99           RITDRGGLRSQFHHVVDIAPTILEAAGIPAPEIVNGVAQKPHDGISLMYT
Mb0682|M.bovis_AF2122/97            GIAAKGEMRWQFHHVIDVAPTILEAAGLPEPLFVNGVQQHPIEGVSMAYS
Rv0663|M.tuberculosis_H37Rv         GIAAKGEMRWQFHHVIDVAPTILEAAGLPEPLFVNGVQQHPIEGVSMAYS
Mvan_4467|M.vanbaalenii_PYR-1       GIAAKGETRNQFHHVIDVVPTILEAAKLPAPTVVNSIQQAPLEGVSMMST
                                     *  :.    .: :* *:.**: :   :. *   ..: * * :*:*:  :

Mflv_5039|M.gilvum_PYR-GCK          LENPNAPTGKETQFYTMLGTRGIWHRGWFANTVHAASPAGWS-----HFD
MSMEG_1451|M.smegmatis_MC2_155      LADPDAPTGKETQFYAMLGTRGIWHKGWFANTVHAATPSGWG-----HFA
MAV_4461|M.avium_104                LDDPNADTGKTTQFYTMLGTRGIWHEGWFANTVHAATPAGWS-----HFD
TH_0315|M.thermoresistible__bu      LADPDADTGKRTQFYSMLGTRGIWSDGWFANTVHAASPAGWS-----NFD
MAB_4307|M.abscessus_ATCC_1997      FDDKDAATTKKRQYYAMLGTRGIWEDGWKASALHAP-ISGKG-----HFD
MMAR_1375|M.marinum_M               FDDAEAADRRRTQYFEIGGLRGIYHEDWMACTYHGRILWRPG--ALPAFS
MUL_2500|M.ulcerans_Agy99           FDDAEAADRRRTQYFEIGGLRGIYHEDWMACTYHGRILWRPG--ALPAFS
Mb0682|M.bovis_AF2122/97            FDDAQAPDRHETQYFEMFGNRGIYHKGWTAVTKH-KTPWILVGEQTVAFD
Rv0663|M.tuberculosis_H37Rv         FDDAQAPDRHETQYFEMFGNRGIYHKGWTAVTKH-KTPWILVGEQTVAFD
Mvan_4467|M.vanbaalenii_PYR-1       LRDRDADETHTVQYFEMFGNRGIYHKGWTAVTKH-RTPWIAD---QPPLD
                                    : : :*   :  *:: : * ***:  .* * : *              : 

Mflv_5039|M.gilvum_PYR-GCK          DDRWELYHVDADRSQVHDLAAEYPEKLDELKALWFSEAQKYNGLPLGDLD
MSMEG_1451|M.smegmatis_MC2_155      DDRWELFHIDADRSQCHDLAAEHPDRLEELKALWFSEADKYNGLPLGDLS
MAV_4461|M.avium_104                ADRWELFHIEADRSQCHDLAAENPDKLEELKALWFAEAARYNGLPLSDLN
TH_0315|M.thermoresistible__bu      ADRWELYHLESDRSQSRDLAAEHPEKLEELKQLWFDEAAKYNGLPLGDLN
MAB_4307|M.abscessus_ATCC_1997      QDKWELFHVDEDRSESTDLADQHPDKLKALIDAWFEEADNNFVLPLDDRL
MMAR_1375|M.marinum_M               DDRWELYDLSRDYSQAVDLSAQFPDKLEQLKALFDAEGVKNNVFPLDDR-
MUL_2500|M.ulcerans_Agy99           DDRWEFYDLFRDYSQAADLSAQFPDKLEQLKALFDAEGVKNNVFPLDDR-
Mb0682|M.bovis_AF2122/97            DDVWELYDTTKDWSQAKDLAKEMPEKLHELQRLWLIEATRYNVLPLDDDT
Rv0663|M.tuberculosis_H37Rv         DDVWELYDTTKDWSQAKDLAKEMPEKLHELQRLWLIEATRYNVLPLDDDT
Mvan_4467|M.vanbaalenii_PYR-1       EDVWELYAP-DDWTQAHDLAAEQPERLAALQRLWLIEAVKYNVVPLDDRS
                                     * **::    * ::  **: : *::*  *   :  *. .   .**.*  

Mflv_5039|M.gilvum_PYR-GCK          IFETMSRW--RPTLSGERSAYVYYPGTADVGIGAVVELRGRSFAVLAEVE
MSMEG_1451|M.smegmatis_MC2_155      ILETTTRW--RPYLTGERTSYTYYPHTAEVGMGAVVELRGQSFKVLAEVT
MAV_4461|M.avium_104                ILETMTRS--RPYLVGERDSYVYYPDCADVGIGAAAEIRGRSFSVLAEAT
TH_0315|M.thermoresistible__bu      LFETLGRW--RPHLSRGRTSYTYYPGTAEVGLGAAVDIRGQSFTVLADVT
MAB_4307|M.abscessus_ATCC_1997      PTELLTIE--RPQFEPRRNRYLYYPDASPVPEGVAVNIRGKSYKIVANTD
MMAR_1375|M.marinum_M               -GRLARALEPRPTILGSRTSISFRQGATRIPEDIIRSAFNRSYSITAVID
MUL_2500|M.ulcerans_Agy99           -GRLARALEPRPTILGERTSISFRQGATRIPEDIIRSAFNRSYSITAVID
Mb0682|M.bovis_AF2122/97            ASRINPDLAGRPVLIRGNTQVLF-SNMGRLSENCVLNLKNKSHTVTAEVE
Rv0663|M.tuberculosis_H37Rv         ASRINPDLAGRPVLIRGNTQVLF-SNMGRLSENCVLNLKNKSHTVTAEVE
Mvan_4467|M.vanbaalenii_PYR-1       FERFNPDIAGRPQLIKGTTQTLF-SGM-RLLENCVLNIKNRSHAVSALIS
                                      .       ** :        :      :  .   .  .:*. : *   

Mflv_5039|M.gilvum_PYR-GCK          VDP-GGANGVVVKHGGAHGGYVMYLQGGRLHFCYNFLGEYEQTLAAPDPV
MSMEG_1451|M.smegmatis_MC2_155      VDS-AEAQGVIFKHGGAHGGHVLFIADGHLHYVYNFLGEREQVLSAPDPV
MAV_4461|M.avium_104                VDT-TGAEGVLFKQGGAHGGHVLFIQDGRLHYVYNFLGERQQEVSSSVPV
TH_0315|M.thermoresistible__bu      VDA-AGAQGVIVKHGAGHGGYVLFLQDGRLHFVYNFMGEEEQRVSSADPI
MAB_4307|M.abscessus_ATCC_1997      IS--AQAQGVIFAHGSRFGGHVLFIKDGRLHYVYNFLGIKPEQEFISAPL
MMAR_1375|M.marinum_M               TPGGSAVEGVLLAAGGYFAGLSLYVQHGIPTFTYNYFGSTYTTVAATEAL
MUL_2500|M.ulcerans_Agy99           TPGGSTVEGVLLAAGGYFAGLSLYVQQGIPKFTYNYFGSTYTTVAATEAL
Mb0682|M.bovis_AF2122/97            VPE-TGAEGVIVAQGASIGGWSLYANDGKLKYCYNLGGIKHFYAESADPL
Rv0663|M.tuberculosis_H37Rv         VPE-TGAEGVIVAQGASIGGWSLYANDGKLKYCYNLGGIKHFYAESADPL
Mvan_4467|M.vanbaalenii_PYR-1       VPD-SGAQGVIVSQGGGVGGWCVYAHENTLKYCYNFFGIEYYFVTAELPL
                                          .:**:.  *.  .*  ::   .   : **  *          .:

Mflv_5039|M.gilvum_PYR-GCK          PPGLHTLGFTYTVTGTAEGSHTPIGDAELFLDTERVASLAEMRSQPGTFG
MSMEG_1451|M.smegmatis_MC2_155      PLGHHIFGVRYERTGTVPNSHTPVGVATLFVDGGAVADLADVQTHPAIFA
MAV_4461|M.avium_104                PLGRHLFGASYARTGTVPDSHTPLGDLTLFIDDEVVGTLAGVSTHPGTFG
TH_0315|M.thermoresistible__bu      PAGRHILGVSYHRTGTVDGSHTPLGEVALYVDGTVVATRPDVRAHPANFG
MAB_4307|M.abscessus_ATCC_1997      TPGNRTLGVEFVRRDKGQYGES-LGTTNLYVDGKLAATGP-MRTQVGTFT
MMAR_1375|M.marinum_M               PAGKATVAMEFDYDG---GGLGKGGLVRLLLNGRDVGQSRIERTVPLGFS
MUL_2500|M.ulcerans_Agy99           PAGKATVAMEFDYDG---GGLGKGGLVRLLLNGRDVGQSRIERTVPLGFS
Mb0682|M.bovis_AF2122/97            PAGAHQVRMEFAYAG---GGLGKGGEVTLYVDGQQVGEGHVEATLAIVFS
Rv0663|M.tuberculosis_H37Rv         PAGAHQVRMEFAYAG---GGLGKGGEVTLYVDGQQVGEGHVEATLAIVFS
Mvan_4467|M.vanbaalenii_PYR-1       PGGQHLVGFEFAYDG---GGLGKGGTVTLYCDGEPVGTGRVERTEPMAFS
                                    . *   .   :   .    .    *   *  :   ..      :    * 

Mflv_5039|M.gilvum_PYR-GCK          LAGASLSVGRNNGSPVSEAYHPPFAFAGGRIARVNIDTS-----GAPYVD
MSMEG_1451|M.smegmatis_MC2_155      LAGGGIAVGRNTGSGVSRSYRVPFPFTGGEIAQVTVDLS-----GEPYED
MAV_4461|M.avium_104                LAGAGITVGRNGGSGVSSRFKAPFVFTGGTIARVTLDLS-----GRPYRD
TH_0315|M.thermoresistible__bu      LAGGGIAVGRNTGQPVSSAYRAPFAFTGGSIAKVIVDIS-----GTPYRD
MAB_4307|M.abscessus_ATCC_1997      LAGDGLCVGYDSGDNVSPQYTNPGRFTGGTIKVVAVDVS-----DESFID
MMAR_1375|M.marinum_M               -ADEGVDIGMDCGTPAADTYEG-TFVFNATIEQVTIQLR-----------
MUL_2500|M.ulcerans_Agy99           -ADEGVDIGMDCGTPAADTYEG-TFVFNATIEQVTIQLR-----------
Mb0682|M.bovis_AF2122/97            -ADDGCDVGMDSGSPVSPDYAPGSNAFNGRIKGVQLAIAEAAAAAGHLVD
Rv0663|M.tuberculosis_H37Rv         -ADDGCDVGMDSGSPVSPDYAPGSNAFNGRIKGVQLAIAEAAAAAGHLVD
Mvan_4467|M.vanbaalenii_PYR-1       -ADEACDVGSDTGSPTSPDYGPHGNGFNGRIDWVKIDIS--TDDHEHLIT
                                     *. .  :* : *  .:  :       .. *  * :              

Mflv_5039|M.gilvum_PYR-GCK          LERDFARAFARD
MSMEG_1451|M.smegmatis_MC2_155      LVTRRATAFARD
MAV_4461|M.avium_104                VETEIALAFSRD
TH_0315|M.thermoresistible__bu      VEREAAMAFARD
MAB_4307|M.abscessus_ATCC_1997      LEKEAQAAFARD
MMAR_1375|M.marinum_M               ------------
MUL_2500|M.ulcerans_Agy99           ------------
Mb0682|M.bovis_AF2122/97            PEHAIRIALARQ
Rv0663|M.tuberculosis_H37Rv         PEHAIRIALARQ
Mvan_4467|M.vanbaalenii_PYR-1       PQDRFNISMARQ