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M. marinum M MMAR_2626 (-)

annotation: hypothetical protein MMAR_2626
coordinates: 3203406 - 3205136
length: 576

MSSEARCGDRDQGVAGGCGSTVQSTAGTYAIAATGGGNNNDGGRGAGGASIAMSGGIEGAGIDWAREQGT
GQPQAAGTAVPGSSRPRWVFRRRLRAGPRRATWRRWFGVAATVLSVAAGTCWAAAWAGGSDQSAALSEWS
PCAAANGAAGMQCAILNVPLDWNLAESAMAQVAVARLPATGAHKLGVIVTNPGGPGISGIDDMAYSGNFW
DRLRQDFDIVTFDPRGVGASRPAIALAGDELVAAVRNQPSIPRTEAQRRSRLEGTTRLVDAAQRGGVLGL
VGTQEVARDLEALRVAMNVESIDYFGFSYGTYLGVVYADMFPGSTHRIVLDSAMNPANDYATLRHDQAVA
FDRAIRAQFDAPEIQRIQALIERLDESPIVGEDGRVLSGLRLLNYVESAAYEPETSVPVLREVLAEASRG
NWAPVIDAVHGPALLVNPADLPYLSVACHDLSTPTQVGDVAALARAWTREAPLTGASRAWSVLPCTVWPT
RAAAPPHRMAAAGSGPTLVIGVAGDPATPPHWGRELAATLVHGQYLQWAGAGHVAYGRAGEPLGTIVNDF
FVSGRLPPAGLELPAD
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_2626--100% (576)hypothetical protein MMAR_2626
M. marinum MMMAR_3297-2e-4229.22% (486) exported protease
M. marinum MMMAR_3295-9e-3828.12% (448) exported protease

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2247c-5e-4229.81% (520) exported protease
M. gilvum PYR-GCKMflv_2904-2e-4129.76% (467) TAP domain-containing protein
M. tuberculosis H37RvRv2223c-5e-4229.81% (520) exported protease
M. leprae Br4923MLBr_01633-3e-4128.07% (481) putative secreted hydrolase
M. abscessus ATCC 19977MAB_1919-1e-3828.60% (465) hypothetical protein MAB_1919
M. avium 104MAV_2241-4e-4528.79% (528) hydrolase, alpha/beta fold family protein, putative
M. smegmatis MC2 155MSMEG_4296-1e-4127.77% (479) protease
M. thermoresistible (build 8)TH_0213-7e-3828.63% (482) Probable exported protease
M. ulcerans Agy99MUL_3101-1e-10490.38% (208) hypothetical protein MUL_3101
M. vanbaalenii PYR-1Mvan_3599-6e-3928.17% (504) TAP domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_0213|M.thermoresistible__bu      --------------------------------------------------
Mvan_3599|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2247c|M.bovis_AF2122/97           --------------------------------------------------
Rv2223c|M.tuberculosis_H37Rv        --------------------------------------------------
MAB_1919|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_2904|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_4296|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01633|M.leprae_Br4923          --------------------------------------------------
MAV_2241|M.avium_104                --------------------------------------------------
MMAR_2626|M.marinum_M               MSSEARCGDRDQGVAGGCGSTVQSTAGTYAIAATGGGNNNDGGRGAGGAS
MUL_3101|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

TH_0213|M.thermoresistible__bu      --------------------------------MWRVGRLMAAALAALLLV
Mvan_3599|M.vanbaalenii_PYR-1       -----------------------------MAAMLRAARLIAALAVT---A
Mb2247c|M.bovis_AF2122/97           -----------------------------MAAMWRRRPLSSALLSFGLLL
Rv2223c|M.tuberculosis_H37Rv        -----------------------------MAAMWRRRPLSSALLSFGLLL
MAB_1919|M.abscessus_ATCC_1997      -----------------------------MMRMRRALPVIFLMLTAA--V
Mflv_2904|M.gilvum_PYR-GCK          -------------------------------------------------M
MSMEG_4296|M.smegmatis_MC2_155      -------------------------------MAACGAMKVRFGLGALLAV
MLBr_01633|M.leprae_Br4923          ------------MTAAHQEPKPSLAAYVSMALSYRDKIARMLLLGTAIAA
MAV_2241|M.avium_104                ---------------------------MGMGLSRRGKSARTLLIWMSIAA
MMAR_2626|M.marinum_M               IAMSGGIEGAGIDWAREQGTGQPQAAGTAVPGSSRPRWVFRRRLRAGPRR
MUL_3101|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

TH_0213|M.thermoresistible__bu      GVFVPPASATPGETPVSNTG---------IAPVWGDCSRFIPNAAALP-T
Mvan_3599|M.vanbaalenii_PYR-1       AAQCPTAAAAPVAVEEPYT----------AAAVWSSCTPWIADVSRIP-T
Mb2247c|M.bovis_AF2122/97           GGLPLAAPPLAGATEEPGAGQTPGAPVVAPQQSWNSCREFIADTSEIR-T
Rv2223c|M.tuberculosis_H37Rv        GGLPLAAPPLAGATEEPGAGQTPGAPVVAPQQSWNSCREFIADTSEIR-T
MAB_1919|M.abscessus_ATCC_1997      PAIPAAAAPLPAPSPSLQAFYD-------QKVVWGGCDSFVTDTSRIP-T
Mflv_2904|M.gilvum_PYR-GCK          SALLVAGCSKVVDGNALVSVPRPG-----TPIDWSPCETGPSDQKRIPPG
MSMEG_4296|M.smegmatis_MC2_155      TVLAAGGCSQVIDGRAIVAVPRPG-----TPVQWLPCNGGAGNQTPIPDS
MLBr_01633|M.leprae_Br4923          VALVLAGCVRVVSGRALMAGPKLG-----EPVAWAPCRP-SNPAVKLPGG
MAV_2241|M.avium_104                VALLLAGCVRVVVGRAVMSGPKLG-----QAVEWTPCRA-ANPKVKLPAG
MMAR_2626|M.marinum_M               ATWRRWFGVAATVLSVAAGTCWAAAWAGGSDQSAALSEWSPCAAANGAAG
MUL_3101|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

TH_0213|M.thermoresistible__bu      ARCGYLPVPLNWAEP---DGPQVQLAVIRVPAD-GPKVGALFVNPGGPGG
Mvan_3599|M.vanbaalenii_PYR-1       AQCGTVAVPVDYAKP---EGAQAQLAIIKVPAS-GPRVGVLIVNPGGPGA
Mb2247c|M.bovis_AF2122/97           ARCATVSVPVDYDQP---GGTQAKLAVIRVPAT-GQRFGALLVNPGGPGA
Rv2223c|M.tuberculosis_H37Rv        ARCATVSVPVDYDQP---GGTQAKLAVIRVPAT-GQRFGALLVNPGGPGA
MAB_1919|M.abscessus_ATCC_1997      ARCAKVKVPVNYDKL---MGAVAELAVLRVPAT-GKRVGALLVNPGGPGG
Mflv_2904|M.gilvum_PYR-GCK          SECGMLSVPVDWDNPEDPDGDVAQLAVLRVPAT-GDRIGSLVVNPGGPGK
MSMEG_4296|M.smegmatis_MC2_155      AECGMLSVPVDYSKP---DGDVARLAMIRFPAT-GDRIGSLVINPGGPGE
MLBr_01633|M.leprae_Br4923          ALCGKLAVPVDYDHH---DDDVAALAMIRFPAT-GDRMGSLVINPGGPGE
MAV_2241|M.avium_104                ALCGKLAVPVDYDHL---DGDVATLAMIRFPAT-GDKIGSLVINPGGPGE
MMAR_2626|M.marinum_M               MQCAILNVPLDWNLA---ESAMAQVAVARLPATGAHKLGVIVTNPGGPGI
MUL_3101|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

TH_0213|M.thermoresistible__bu      SAVNTVAGMAAALAGTDVTSRFDLIGFDPRGVGHSLPELRCRTDAEFDAY
Mvan_3599|M.vanbaalenii_PYR-1       SAVNTVASMGGALAGSEIGRHFDLVGIDPRGVGHSTPELRCRTDAEFDAF
Mb2247c|M.bovis_AF2122/97           SAVDMVAAMAPAIADTDILRHFDLVGFDPRGVGHSTPALRCRTDAEFDAY
Rv2223c|M.tuberculosis_H37Rv        SAVDMVAAMAPAIADTDILRHFDLVGFDPRGVGHSTPALRCRTDAEFDAY
MAB_1919|M.abscessus_ATCC_1997      SGVDLAAGMGAKLGDSAIGQSFDIVGFDPRGVGGSTPTLRCRTDAEFDAF
Mflv_2904|M.gilvum_PYR-GCK          SGVEAAAAMVSTLP-EEVLERFDIVGFDPRGVANSNPAVWCNSDADNDRL
MSMEG_4296|M.smegmatis_MC2_155      SGVESALSLLPSLP-QEVKERFDIVGFDPRGVASSSPAVWCNSDADNDRL
MLBr_01633|M.leprae_Br4923          SGIEAALGVVQTLP-KRVRERFDLVGFDPRGVGASRPAVWCNSDADNDRL
MAV_2241|M.avium_104                SGIEAALGVVQSLP-KRVRERFDLVGFDPRGVGASRPAVWCNSDADNDRL
MMAR_2626|M.marinum_M               SGIDDMAYSGNFWD--RLRQDFDIVTFDPRGVGASRPAIALAGDELVAAV
MUL_3101|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

TH_0213|M.thermoresistible__bu      RREPMADYSPAGVAHIEELHRRFAQSCLDRNGADFLAGLGTANAARDMDA
Mvan_3599|M.vanbaalenii_PYR-1       RAEPLADYSPGGVAHIEGVLRDFAAQCLDRMGAEFLASVGTATAARDMDV
Mb2247c|M.bovis_AF2122/97           RRDPMADYSPAGVTHVEQVYRQLAQDCVDRMGFSFLANIGTASVARDMDM
Rv2223c|M.tuberculosis_H37Rv        RRDPMADYSPAGVTHVEQVYRQLAQDCVDRMGFSFLANIGTASVARDMDM
MAB_1919|M.abscessus_ATCC_1997      RKEPLADYSQAGVAHIEDVYRQYVNECANRMGLDFLANAGTASAARDMDI
Mflv_2904|M.gilvum_PYR-GCK          RADNVVEYTAEGVAHLESLTKEFIQRCVDKMGTDFLANVGTASVVKDLDA
MSMEG_4296|M.smegmatis_MC2_155      RADPTVEYTPEGVAHLEAETKAFVQRCVDKMGTEFLANVGTENVAKDLDA
MLBr_01633|M.leprae_Br4923          RSESQVDYSPAGVAHIEDETKQFIGRCIAKMGKIFLENIGTVNVAKDLDA
MAV_2241|M.avium_104                RTEPNVDYSPAGVAHIEDETKQFVGRCVDKMGKKFLANVGTVNVARDLDA
MMAR_2626|M.marinum_M               RNQPSIPRTEAQRRSRLEGTTRLVDAAQRG---GVLGLVGTQEVARDLEA
MUL_3101|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

TH_0213|M.thermoresistible__bu      VRAALGE----EQINYLGFSYGTRLGAAYAEQFPDRVRTMVLDGAVDPSQ
Mvan_3599|M.vanbaalenii_PYR-1       VRDALGE----DRVNYLGFSYGTQLGAVYAARYPDRVRAMVLDGAVDPSL
Mb2247c|M.bovis_AF2122/97           VRQALGD----DQINYLGYSYGTELGTAYLERFGTHVRAMVLDGAIDPAV
Rv2223c|M.tuberculosis_H37Rv        VRQALGD----DQINYLGYSYGTELGTAYLERFGTHVRAMVLDGAIDPAV
MAB_1919|M.abscessus_ATCC_1997      VRSIVGAGAADTRLNYLGYSYGTELGTQYAEYFPQNVRTMVLDGAIDPTI
Mflv_2904|M.gilvum_PYR-GCK          LRVALGD----EKLTYLGYSYGTRIGASYAEQFPQNVRAMVLDGAIDPNA
MSMEG_4296|M.smegmatis_MC2_155      IRAALGD----DKLTYLGYSYGTRIGATYAEQFPDKVRAMILDGAIDPNA
MLBr_01633|M.leprae_Br4923          IRAALGD----DKLTYLGYSYGTRIGAAYAEAYPQNVRSMILDGAVDPNA
MAV_2241|M.avium_104                IRAALGD----DKLTYLGYSYGTRIGSAYAEAYPHNVRAMILDGAVDPNA
MMAR_2626|M.marinum_M               LRVAMNV----ESIDYFGFSYGTYLGVVYADMFPGSTHRIVLDSAMNPAN
MUL_3101|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

TH_0213|M.thermoresistible__bu      DPLAGTTRQMAGFQAAFDEYAADCARSPDCPLGTDPAKWVARYHELVDPL
Mvan_3599|M.vanbaalenii_PYR-1       DPITESLNQQAGFQKAFEAYAADCAESVGCPLGTDPAQFVARFHQLVDPL
Mb2247c|M.bovis_AF2122/97           SPIEESISQMAGFQTAFNDYAADCARSPACPLGTDSAQWVNRYHALVDPL
Rv2223c|M.tuberculosis_H37Rv        SPIEESISQMAGFQTAFNDYAADCARSPACPLGTDSAQWVNRYHALVDPL
MAB_1919|M.abscessus_ATCC_1997      DPVESNVRQMTGFQVAFNDYAADCAKDPKCPLGPDPSQAVKRFHQLIDPL
Mflv_2904|M.gilvum_PYR-GCK          DPLEADVRQAAAFQQAFDDYAADCAIDDDCPLGTDPAKAVEVYHSLVWPL
MSMEG_4296|M.smegmatis_MC2_155      DPVEESIRQAAAFQKAFDDYAADCAKSPDCPLGTDPAKAVDVYKSIIDPL
MLBr_01633|M.leprae_Br4923          DPIEADLRQAKGFQDAFNNYAADCARKLSCPLGADPAKAVDVYHNLVNPL
MAV_2241|M.avium_104                DQIEADLRQAKGFQDAFNNFAAECAKQPNCPLGTDPAKAVDVYHSLVDPM
MMAR_2626|M.marinum_M               DYATLRHDQAVAFDRAIR--------------AQFDAPEIQRIQALIERL
MUL_3101|M.ulcerans_Agy99           ---------------------------------------------MIERL
                                                                                 ::  :

TH_0213|M.thermoresistible__bu      VHR-------PAPTSDPRGLSYQDAITGTVQALYSRQYWKYLTSGLLGLR
Mvan_3599|M.vanbaalenii_PYR-1       VTR-------PAATSDPRGLGYQDAITGTASGLYSQRYWPYLTSGLLGLQ
Mb2247c|M.bovis_AF2122/97           VQK-------PGKTSDPRGLSYADATTGTINALYSPQRWKYLTSGLLGLQ
Rv2223c|M.tuberculosis_H37Rv        VQK-------PGKTSDPRGLSYADATTGTINALYSPQRWKYLTSGLLGLQ
MAB_1919|M.abscessus_ATCC_1997      VTK-------PAKTNDPRGLSYQDAITGTIQAMYTPRYWKYLTSGLSGLA
Mflv_2904|M.gilvum_PYR-GCK          VDE-------PAETSDPRGLSYNDAVVGTILPLYSPALWRHLTQALGEVK
MSMEG_4296|M.smegmatis_MC2_155      VEN-------PAKTRDGRGLSYSDATVGTILPLYSPNLWRHLTDALTALK
MLBr_01633|M.leprae_Br4923          VDPNNPMVSRPAPTKDPRGLSYSDAIVGTIMTLYSPTLWHHLTDGLSELV
MAV_2241|M.avium_104                VDPDNPMVGRPIPTNDPRGLSYSDAIVGTIMALYSPNLWHHLTDGLSELV
MMAR_2626|M.marinum_M               DES-------PIVGEDGRVLSGLRLLNYVESAAYEP---ETSVPVLREVL
MUL_3101|M.ulcerans_Agy99           DES-------PIVGEDGRVLSGLRLLNYVESAAYEP---ETSVPVLREVL
                                              *    * * *.       .    *        .  *  : 

TH_0213|M.thermoresistible__bu      RGTDPVDLLLLADEYLRRDVNGHYQNQQDAFTAIRCVDAPYPTDPAVWAE
Mvan_3599|M.vanbaalenii_PYR-1       RGTDPGDLLLLADDYQQRDRNGHYKNRQDAFNAIRCVDAVYPTDSAPWVE
Mb2247c|M.bovis_AF2122/97           RGSDAGDLLVLADDYDGRDADGHYSNDQDAFNAVRCVDAPTPADPAAWVA
Rv2223c|M.tuberculosis_H37Rv        RGSDAGDLLVLADDYDGRDADGHYSNDQDAFNAVRCVDAPTPADPAAWVA
MAB_1919|M.abscessus_ATCC_1997      DGSGPDDLLWLADQYQERDDHGRYDNLQDAFNSIRCVDGPTPKDSAPWVA
Mflv_2904|M.gilvum_PYR-GCK          EGKG-DTMLALADLYMERNAQGRYTNSTDVRIAVNCVDKPAITDRATLVE
MSMEG_4296|M.smegmatis_MC2_155      KGDG-NLMLALADLYMGRDAKGHYNNSTDVRVAVNCMDKPAIKDKATVVE
MLBr_01633|M.leprae_Br4923          DHRG-DTLLALADMYMRRDSQGHYTNATDARVAVNCVDQPPITDRAKVID
MAV_2241|M.avium_104                DHHG-DTLLALADMYMRRDAHGHYTNATDARVAINCVDQPPITDRAKVID
MMAR_2626|M.marinum_M               AEASRGNWAPVIDAVHGPALLVNPADLP--YLSVACHDLSTPTQVGDVAA
MUL_3101|M.ulcerans_Agy99           AEASRGNWAPVIDAVHGPALLVNPADLP--YLSVACHDLSTPTQVGDVAA
                                       .      : *         .  :      :: * *     : .    

TH_0213|M.thermoresistible__bu      TDRQVRAVAPFLSYGEFTGFAPRNVCAMWPVPPTSTPAPATSPGPGKVVV
Mvan_3599|M.vanbaalenii_PYR-1       ADRRSREVAPFLSYGPFTGFAPRDLCAMWPVPPTPVVGVASSPGPGKVVV
Mb2247c|M.bovis_AF2122/97           ADQRIRQVAPFLSYGQFTGSAPRDLCALWPVPATSTPHPAAPAGAGKVVV
Rv2223c|M.tuberculosis_H37Rv        ADQRIRQVAPFLSYGQFTGSAPRDLCALWPVPATSTPHPAAPAGAGKVVV
MAB_1919|M.abscessus_ATCC_1997      ADKTLREQAPFSSYGSFTGYAPRDMCAFWPVPPTSTPHTPSTPGLAPVVV
Mflv_2904|M.gilvum_PYR-GCK          QDRRVRDAAPFMAYGEFTGLAPMPTCGFWPVPPTSKPHEISVTGLPPILV
MSMEG_4296|M.smegmatis_MC2_155      QDKRLREVAPFMSYGEFTGDAPLGTCAFWPVPPTSEPHELKVEGLPPILV
MLBr_01633|M.leprae_Br4923          EDRRSREVAPFMSYGKFTGDAPLGTCAFWPVPPTSKPHIVSAPGLAPTVV
MAV_2241|M.avium_104                EDRRSREIAPFMSYGQFTGNAPLGTCAFWPVPPTSKPHTISAPGLAPTVV
MMAR_2626|M.marinum_M               LARAWTREAPLTGASRAWSVLP---CTVWPTRAAAPPHRMAAAGSGPTLV
MUL_3101|M.ulcerans_Agy99           LARAWTREAPLTGASRAWSVLP---CTVWPTRAAAPPHRMTAAGSGPTLV
                                      :     **: . .   .  *   * .**. .:.        *    :*

TH_0213|M.thermoresistible__bu      VSTTRDPATPHEAGLALARQLDAA--LITFDGAQHTVVFNGNPCVDTAVL
Mvan_3599|M.vanbaalenii_PYR-1       VSTTGDPATPYQAGVNLAQQMDAR--LITFEGTQHTVVFNGDACVDTATV
Mb2247c|M.bovis_AF2122/97           VSTTHDPATPYQSGVDLARQLGAP--LITFDGTQHTAVFDGNQCVDSAVM
Rv2223c|M.tuberculosis_H37Rv        VSTTHDPATPYQSGVDLARQLGAP--LITFDGTQHTAVFDGNQCVDSAVM
MAB_1919|M.abscessus_ATCC_1997      ISTTHDPATPYEAGVALARQLGGS--LISYEGTQHTVAFNGEACVDDVVT
Mflv_2904|M.gilvum_PYR-GCK          VSTTNDPATPYQAGVNLARQLGGA--LVTFEGTQHTVALQGDSCVDDIVV
MSMEG_4296|M.smegmatis_MC2_155      VSTTNDPATPYQAGVDLARQLGGT--LVTFEGTQHTVVFQGNKCVDDVAA
MLBr_01633|M.leprae_Br4923          VSTTHDPATPYKAGVDLANQLRGS--LLTFDGTQHTVVFQGDSCVDDYVT
MAV_2241|M.avium_104                VSTTHDPATPYKAGVDLANELRSS--LLTYDGTQHTVVFQGDGCIDNYVT
MMAR_2626|M.marinum_M               IGVAGDPATPPHWGRELAATLVHG-QYLQWAGAGHVAYGRAGEPLGTIVN
MUL_3101|M.ulcerans_Agy99           IGVAGDPATPPHWGRELAATSYTAISAMGWRGT----SLRRAEPLGTIVN
                                    :..: ***** . *  **         : : *:           :.  . 

TH_0213|M.thermoresistible__bu      NFLIDGVPPPNGLAC---
Mvan_3599|M.vanbaalenii_PYR-1       EFLVNSTPPPAGLRC---
Mb2247c|M.bovis_AF2122/97           HYFLDGTLPPTSLRCAP-
Rv2223c|M.tuberculosis_H37Rv        HYFLDGTLPPTSLRCAP-
MAB_1919|M.abscessus_ATCC_1997      RYFVDGTVPPKDVRC---
Mflv_2904|M.gilvum_PYR-GCK          PYLIDGSVPPPDTRC---
MSMEG_4296|M.smegmatis_MC2_155      TYLIDVEVPPADTRC---
MLBr_01633|M.leprae_Br4923          EYLIGGTTPPSGAKC---
MAV_2241|M.avium_104                AYLVGGTIPPSGAKC---
MMAR_2626|M.marinum_M               DFFVSGRLPPAGLELPAD
MUL_3101|M.ulcerans_Agy99           DFFVSGRLPPAGLELPAD
                                     :::.   ** .