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LNESRTRSSSAMTDNRIAFLDQAAFLRLRATGFETVGQTLWIYDREADMDGLRRFNENLGYGLLGRRIER SPLPFGRPRWVAYHEAPDIDVAATPRPRSEITAWLDERAQIPVDPEYGPCWHLGVLPLQDGGTAVSVVIT HSVVDGVAGGLAVFEAINGITRDFGYPPPGSRGRMEGLLVDLWDALRGLPEVFRALLALILIVLRRDTGA AGQTGKPPTVSDGADEPIVTPSVTAFCDLETWDSCALDLSGSSGSLFVSFATRLAQLMGRVRATDGAVTI IMPVSERTNDDTRANAVTAITFDLDPDRARTDLQFIRNETKQSLSALKDTPNELLKPLPLVPYTPKWLAR KMEVLAMGTSDLPVGCSNLGELSQALTRVDGTGARYSSARMFNRGATRQRFERESGELYLFSGRLENSVF ISVSAYQPGAENSNQYLRGLVEQTLADYSLKAELLG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2354 | - | - | 100% (457) | hypothetical protein MMAR_2354 |
| M. marinum M | MMAR_1180 | - | e-104 | 45.50% (444) | Fatty acyl-AMP ligase FadD28_1 and polyketide synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4701 | - | 3e-99 | 41.61% (459) | hypothetical protein MAB_4701 |
| M. avium 104 | MAV_2003 | - | 2e-98 | 50.92% (379) | hypothetical protein MAV_2003 |
| M. smegmatis MC2 155 | MSMEG_4729 | - | 4e-99 | 42.06% (447) | hypothetical protein MSMEG_4729 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1530 | - | 0.0 | 99.34% (457) | hypothetical protein MUL_1530 |
| M. vanbaalenii PYR-1 | Mvan_4076 | - | 9e-05 | 29.17% (144) | hypothetical protein Mvan_4076 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2354|M.marinum_M ----------MLNESRTRSSSAMTDNRIAFLDQAAFLRLRATGFETVGQT
MUL_1530|M.ulcerans_Agy99 ----------MLNESRTRSSAAMTDNRIAFLDQAAFLRLRATGFETVGQT
MAV_2003|M.avium_104 ------------------------MARLALLDQAAFLRLRATGQGSTVQC
MAB_4701|M.abscessus_ATCC_1997 MPGQIRHMRKSLSRRRTSKGAAAMDNRLALADEALLAEHHAAGMNVIIQV
MSMEG_4729|M.smegmatis_MC2_155 ----MRFGDSSMTP-STTPATVATDDRLSHTDQLLFLGQRATGQELVAQC
Mvan_4076|M.vanbaalenii_PYR-1 ------------MSNEPELDAAGLPEELSPLDQILHRGEGNPRTRSGIMT
.:: *: .
MMAR_2354|M.marinum_M LWIYDREADMDGLRRFNENLGYGLLGR--RIERSPLPFGRPRWVAYHEAP
MUL_1530|M.ulcerans_Agy99 LWIYDREADMDGLRRSNENLGYGLLGR--RIERSPLPFGRPRWVAYHEAP
MAV_2003|M.avium_104 AWIYDRDVNIAELRAFNDNLRFGLLGR--RIERSPLPFGRHRWVLDRRPP
MAB_4701|M.abscessus_ATCC_1997 TWLYSHAIDLDALQRFRHNLGRGLLGR--RIEAPALPIARHRWVIDHGPA
MSMEG_4729|M.smegmatis_MC2_155 VWVYERPVEIDKLRDFHRNFGHGLAGR--LIERSPLPFGRHRWVAAPGPA
Mvan_4076|M.vanbaalenii_PYR-1 LELLDTTPDWDTFRTRFDNASRKVLRLRQKVVTPTLPTAAPRWVVDPDFN
: . : :: * : : ..** . ***
MMAR_2354|M.marinum_M D-IDVAATPRPRSEITAWLDERAQIPVDP---EYGPCWHLGVLP-LQDGG
MUL_1530|M.ulcerans_Agy99 D-IDVAATPRPRSEITAWLDERAQIPVDP---EYGPCWHLGVLP-LQDGG
MAV_2003|M.avium_104 D-IAWEPR-QPRCEIGAWLERRARVAVDP---EHGPTFHLGVLP-LDDGG
MAB_4701|M.abscessus_ATCC_1997 D-IDIEERARPRAEFSEWVDERSQLHIDP---ESGPGWHIGVLP-LQDGT
MSMEG_4729|M.smegmatis_MC2_155 APLDFAEQPRPREELGDWADARAQLPIDP---EVGPGWHMGVLS-MTDGS
Mvan_4076|M.vanbaalenii_PYR-1 LDFHVRRVRVPQPGTFRQVMDLAEIAAQSPLDISRPLWTATLIEGVENGR
: *: :.: :. * : :: : :*
MMAR_2354|M.marinum_M TAVSVVITHSVVDGVAGGLAVFEAINGITRDFGYPPP-------------
MUL_1530|M.ulcerans_Agy99 TAVSVVITHSVVDGVAGGLAVFEAINGITRDFGYPPP-------------
MAV_2003|M.avium_104 AAVTLVASHCVVDGLGLVTAVAEAVKGERRDLGYPQP-------------
MAB_4701|M.abscessus_ATCC_1997 TAISLVLSHNLIDGLGLALVIVEAVMGRTRDLGYPLP-------------
MSMEG_4729|M.smegmatis_MC2_155 TAVSLVISHCLIDGLGTLQTIADAVKGETVDFGYAAP-------------
Mvan_4076|M.vanbaalenii_PYR-1 AALMVHLSHAVTDGVGGVEMFANLYDFERDPPPQSTPPLPIPSDLSPNDL
:*: : :* : **:. . : . *
MMAR_2354|M.marinum_M ---GSRGRMEGLLVDLWDALRGLPEVFRALLALILIVLRR--DTGAAG--
MUL_1530|M.ulcerans_Agy99 ---GSRGRMEGLLVDLWDALRGLPEVFRALLALILIVLRR--DTGAAG--
MAV_2003|M.avium_104 ---NSRSRWRAVREDLADAVAALPSATRALIATLLLLLRVSPDRRVQP--
MAB_4701|M.abscessus_ATCC_1997 ---LSRRRLRALGQDVRQTARDVPQATRALVAAVRLGRKQARDKNLPGLA
MSMEG_4729|M.smegmatis_MC2_155 ---GSRGRLQAVLADLRQTARDLPQTAATLVRAGRLAIRRRHEVALS---
Mvan_4076|M.vanbaalenii_PYR-1 MRAGLNRLPGTIVGGVRDALFGAAQAVGHVVRDPVSRLGSAFDYAMSGLR
. : .: :: ... :: :
MMAR_2354|M.marinum_M -QTGKPPTVSDGADEPIVTPSVTAFCDLETWDSCALDLSGSS-GSLFVSF
MUL_1530|M.ulcerans_Agy99 -QTGKPPTVSDGADEPIVTPSVTAFCDLETWDSCALDLSGSS-GSLFVSF
MAV_2003|M.avium_104 -RAQRRGDFVPRDDASNTSGSVTIHTDAAAWEARARALNGSG-NSLFVAF
MAB_4701|M.abscessus_ATCC_1997 PVAVRPAGSTAPSDEVVLVPAITIYVGLDAWDARAEALGGAS-HTLAAAF
MSMEG_4729|M.smegmatis_MC2_155 AKPRRDFGPDGRSD--VVAPAIACYVPLEEWDLRAAALGGNS-HSLVAAF
Mvan_4076|M.vanbaalenii_PYR-1 VVGPVADPSPILRRRSLSSRSDAIDIEFGDLHRAAKAAGGSINDAYLAGL
: : . * .* : ..:
MMAR_2354|M.marinum_M ATRLAQLMGRVRATDGAVTIIMPVSERTNDDTRANAVTAITFDLDPDRAR
MUL_1530|M.ulcerans_Agy99 ATRLAQLMGRVRVTDGAVTIIMPVSERTNDDTRANAVTAITFDLDPDRAR
MAV_2003|M.avium_104 AARLAHRMGRVLADGKSVTVVLPVSDRAPDDDRANALTSITLTVDGAAVA
MAB_4701|M.abscessus_ATCC_1997 AARFGERIGRRRAHDGAITLQIPISDRTENDTRAMALSYARVSIDPVSLT
MSMEG_4729|M.smegmatis_MC2_155 AAKLGELMGRRRSDDGTVLLHVPISDRAPGDTRGNAAYIVNAHLDPTDVT
Mvan_4076|M.vanbaalenii_PYR-1 CGALRLYHEAKGVPIDTLPMAVPVNLRSEADPAGGNRFVGVNLAAPIGVS
. : :: : :*:. *: * .
MMAR_2354|M.marinum_M TDLQFIRNETKQSLSALKDTPNELL-KPLPLVPYTPKWLARKME----VL
MUL_1530|M.ulcerans_Agy99 TDLQFIRNETKQSLSALKDTPNELL-KPLPLVPYTPKWLARKME----VL
MAV_2003|M.avium_104 DDLTDVRADVKRSLASLQHRPNEML-AGLPLIPFIPRWLVRRGE----SL
MAB_4701|M.abscessus_ATCC_1997 TDLREVRAAIKQTLKTLKESPDESK-LLLWLPSFAPERTLKRMV----AR
MSMEG_4729|M.smegmatis_MC2_155 KDLSGARSAIRQALEAYRQEPDETL-QLLPLTPFIPQRAVARGS----QV
Mvan_4076|M.vanbaalenii_PYR-1 DPEVRIQDIRSQMTRKRDERAMDMVGAIAPVVSLLPDTVLESMAGSFVNS
: : . . : : . *
MMAR_2354|M.marinum_M AMGTSDLPVGCSN--LGELSQALTRVDGTGARYSSARMFNRGATRQRFER
MUL_1530|M.ulcerans_Agy99 AMGTSDLPVGCSN--LGELSQALTRVDGTGARYSSARMFNRGATRQRFER
MAV_2003|M.avium_104 AMASSQLPVGCSN--VGSLDGAVGRIDGADATEVSMRLVVL-TTDVRY--
MAB_4701|M.abscessus_ATCC_1997 MPADPDQSVFCSY--LGDLHSMIGWPAGTLADFQNARATGQRERRQLLER
MSMEG_4729|M.smegmatis_MC2_155 VLNLTDLPVSCSN--LGDIDPLVSRIDGAAAEYLILRGVDRRVSREFLEN
Mvan_4076|M.vanbaalenii_PYR-1 DVQASNVPVYAGDTFIAGAKVLRQYGLGPLPGVAMMVVLISRSGYCTVTA
.: .* .. :. *. .
MMAR_2354|M.marinum_M ESGELYLFSGRLENSVFIS----VSAYQPGAENSNQYLRGLVEQTLADYS
MUL_1530|M.ulcerans_Agy99 ESGELYLFSGRLENSVFIS----VSAYQPGAENSNQYLRGLVEQTLADYS
MAV_2003|M.avium_104 --GVVW--------------------------------------------
MAB_4701|M.abscessus_ATCC_1997 TGGRMFILSGRLNGKIFIS----VGAYQPGATNTKEALRELAELTLADFS
MSMEG_4729|M.smegmatis_MC2_155 RNGLLTVLAGRVDDKMSIS----VIGYRPGGPNDKPQLRELVAKALAEFD
Mvan_4076|M.vanbaalenii_PYR-1 RYDRAAITDPDLLAQCLLAGFDEVLALGGDGRAVPATFTAQTTPPVDSAR
.
MMAR_2354|M.marinum_M LKAELLG
MUL_1530|M.ulcerans_Agy99 LKAELLG
MAV_2003|M.avium_104 -------
MAB_4701|M.abscessus_ATCC_1997 LPGEIH-
MSMEG_4729|M.smegmatis_MC2_155 LVGTIA-
Mvan_4076|M.vanbaalenii_PYR-1 LNGSGPQ