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VSAPAGASIRALIAFGRNDIRGTYREPLLVMIVVAPAIWTSAVALLTPRVTTMLADRNGFDLRPYYPLIL TAFLLLTSIIIVGGLAAFLVLDEVDAGTLAALRVTPVPLSTFFVYRAATVMVVTTIYVVATLSLSGILEL RLLPSLIPIGLLAGLSAVVTLLLILAVANNKIQGLAAVRALGMLIAGLPCLPWFIHSNWNFVFAVLPPYW PAKAFWLASDHATWWPYLVAGSAYNLALAWALFRRFHAKHVASV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2028 | - | - | 100% (254) | antibiotic-transport integral membrane leucine, alanine and valine rich protein ABC transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2705c | - | 1e-111 | 81.15% (244) | antibiotic ABC transporter transmembrane protein |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv2686c | - | 1e-111 | 81.15% (244) | antibiotic ABC transporter transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1860 | - | 1e-106 | 74.49% (243) | antibiotic ABC transporter membrane protein |
| M. avium 104 | MAV_5182 | - | 9e-07 | 24.73% (182) | ABC-type drug export system, membrane protein |
| M. smegmatis MC2 155 | MSMEG_1504 | - | 1e-103 | 72.06% (247) | antibiotic ABC transporter transmembrane protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0774 | - | 1e-92 | 65.29% (242) | putative antibiotic-transport integral membrane leucine and |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2705c|M.bovis_AF2122/97 --MRAISSLAGPRALAAFGRNDIRGTYRDPLLVMLVIAP-------VIWT
Rv2686c|M.tuberculosis_H37Rv --MRAISSLAGPRALAAFGRNDIRGTYRDPLLVMLVIAP-------VIWT
MMAR_2028|M.marinum_M --MSAPAG-ASIRALIAFGRNDIRGTYREPLLVMIVVAP-------AIWT
MAB_1860|M.abscessus_ATCC_1997 --------MMPIRVWAAFGRNDIRGTYRDPLLIMVVLAP-------IIWT
MSMEG_1504|M.smegmatis_MC2_155 --MTEVLPAGTLRAVAAFGRKDIRGTYRDPLLIMLVVAP-------VIWT
Mvan_0774|M.vanbaalenii_PYR-1 ---MSVSMTPRLRAWAAFGRNDLRGTYRDPLLVMLVLAP-------AIWT
MAV_5182|M.avium_104 MSVDNAAAATLVRAPRGWQRVGALSSRVGAFAIVEIQKLQHDRTELVTRM
*. .: * . .: .: :: :
Mb2705c|M.bovis_AF2122/97 TGVALLTPLFTEMLARRYGFDLVGY-YPLILTAFLLLTSIIVAGALAAFL
Rv2686c|M.tuberculosis_H37Rv TGVALLTPLFTEMLARRYGFDLVGY-YPLILTAFLLLTSIIVAGALAAFL
MMAR_2028|M.marinum_M SAVALLTPRVTTMLADRNGFDLRPY-YPLILTAFLLLTSIIIVGGLAAFL
MAB_1860|M.abscessus_ATCC_1997 TGVAVLTPQATDLLSATRGFDLVPY-YPLVLTAFLLLTSIIIPGALAAFL
MSMEG_1504|M.smegmatis_MC2_155 SLVAVLTPRFTETLGARYDFDLVPY-YPLVLTGFLLLTSIIVAGGLGAFL
Mvan_0774|M.vanbaalenii_PYR-1 IGTAVVVPRLSVALAQRYDFDLVPY-YPLVVTGLLLLTSIIIVGGLAAFL
MAV_5182|M.avium_104 VQPALWLLIFGTTFSHLHMIDTGPVSYLAFLAPGIIAQSALFISIFYGIQ
*: :. :* * .:: :: * :. . : .:
Mb2705c|M.bovis_AF2122/97 VLDDVDAGTMTALRVTPVPLSVFFGYRAATVMVVTTIYVVATMSCSGILE
Rv2686c|M.tuberculosis_H37Rv VLDDVDAGTMTALRVTPVPLSVFFGYRAATVMVVTTIYVVATMSCSGILE
MMAR_2028|M.marinum_M VLDEVDAGTLAALRVTPVPLSTFFVYRAATVMVVTTIYVVATLSLSGILE
MAB_1860|M.abscessus_ATCC_1997 VLDDVDAGTLTALRVTPVPMSGYFLYRAATVVVITTVYVVATLSLSGILE
MSMEG_1504|M.smegmatis_MC2_155 VLDEVDAGTMTALRVTPVPIATFFAYRAVTVMLVTTVYVVATLPLSGILA
Mvan_0774|M.vanbaalenii_PYR-1 VLDEIDAGTLTALRVTPVTLASFFGYRAATVVAVTTAYVAVTIPLTGLLP
MAV_5182|M.avium_104 IIWDRDAGVLAKLMVTPAPASALVTGKAFAAGVRSVAQVVGVLALAYLMR
:: : ***.:: * ***.. : . :* :. :. *. .:. : ::
Mb2705c|M.bovis_AF2122/97 PGLVSS----LIPIGLVAG----LSAVVTLLLILAVANNKIQGLAMVRAL
Rv2686c|M.tuberculosis_H37Rv PGLVSS----LIPIGLVAG----LSAVVTLLLILAVANNKIQGLAMVRAL
MMAR_2028|M.marinum_M LRLLPS----LIPIGLLAG----LSAVVTLLLILAVANNKIQGLAAVRAL
MAB_1860|M.abscessus_ATCC_1997 PGVLPA----LIPIGMLSG----LSAVVTLLLVIAFANNKIQGLAAVRAL
MSMEG_1504|M.smegmatis_MC2_155 PGLVGP----LVPIGMLAG----LSAVVTLLAVVALAGDKIQGIAMVRAL
Mvan_0774|M.vanbaalenii_PYR-1 SSVVWP----LIPIGMVAG----LSSVVTMLLIVAVASNKVQGIAMLRLL
MAV_5182|M.avium_104 IGLTVNPLRILAAMGIVMLGAAFFACLSMTLAGLVRNRDRLMGIGQAITM
: * .:*:: ::.: * :. ::: *:. :
Mb2705c|M.bovis_AF2122/97 GMLIAGLPCLPWFISSNWNLAFGVLPPY----WAAKAFWVASDHG-TWWP
Rv2686c|M.tuberculosis_H37Rv GMLIAGLPCLPWFISSNWNLAFGVLPPY----WAAKAFWVASDHG-TWWP
MMAR_2028|M.marinum_M GMLIAGLPCLPWFIHSNWNFVFAVLPPY----WPAKAFWLASDHA-TWWP
MAB_1860|M.abscessus_ATCC_1997 GMLIAGLPCLPWFIHSNWGYAFGVLPPF----WAAKAFWVASAHG-MWWP
MSMEG_1504|M.smegmatis_MC2_155 GMLIAGLPCVPWFIDSAWNLAFGVLPPY----WAAKAFWVASAHG-TWWP
Mvan_0774|M.vanbaalenii_PYR-1 GLLIAGIPCLPWFVDSAWNLAFGVLPPY----WAAKAFWVACANG-TWWP
MAV_5182|M.avium_104 PLFFASNALYPVELMPTWLHVLSKINPLSYEVNALRALLIGTPFNPVDIA
:::*. . * : . * .:. : * . :*: :. .
Mb2705c|M.bovis_AF2122/97 YLVGGAVYNLAIVWVLFRRFRAKHA---
Rv2686c|M.tuberculosis_H37Rv YLVGGAVYNLAIVWVLFRRFRAKHA---
MMAR_2028|M.marinum_M YLVAGSAYNLALAWALFRRFHAKHVASV
MAB_1860|M.abscessus_ATCC_1997 FVLIGVAYNLLIAWALLRRFLAKNL---
MSMEG_1504|M.smegmatis_MC2_155 YLVVGAVYNVVVAWPLFRRFQARHG---
Mvan_0774|M.vanbaalenii_PYR-1 YLIGGVVFNAAAGWPLLRRFVAKNT---
MAV_5182|M.avium_104 VLAAAAVTGILTASTLLRRLVA------
: . . . *:**: *