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RPGQPAASTSHPGPPQFRIVNMVTLALVGFVGGLITGISPCILPVLPVVFFSGAHGGATVATTQTGVSTP DPKAARVQTRPYRVIAGLVLSFCLVTLTGSALLSLLHLRQDTIRWVALAALVAIGLGLIFPRLEQWLQRP FSRIPHNSISAGGTGFGLGLALGVLYVPCAGPVLTAIILAGATSRIGLNTVVLTCAFALGTALPLLFFAL AGRETAGRVSAFRRRQREIRIGAGVVTILLAVALVLNLPATLQRAIPDYTSALQGLPEQVGGPNQIGTNL GGIGGLVTDQNAQLSNCTNGAAQPQDCGSAPDITGISGWLNTPEHQPIRLSSLRGRVVLVDFWAYSCINC QRAIPHVVGWYRAYKDSGLEVIGVHTPEYAFEKVPENVAAGAADLNITYPIALDNNYSTWTNYRNAYWPA EYLIDASGTVRHIKFGEGDYDGTENLIRRLLTDANPGAKLPAPVDAADTTPALSLTPETYFGVGKAVNFA GSGYDQGSATFSYPLALPPDTFALQGPWSLDHQRATADGDDCRIKLNYLAKNVYLVVGGTGTLTVTGAGK STTLRIGGAPTSHQIVAGDQVQRTTIEVHPSKGLQVYSFTYG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1835 | dipZ | - | 100% (603) | integral membrane C-type cytochrome biogenesis protein DipZ |
| M. marinum M | MMAR_0873 | ccsA | 2e-14 | 27.48% (222) | cytochrome C-type biogenesis protein, CcsA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2899 | dipZ | 0.0 | 68.20% (607) | integral membrane C-type cytochrome biogenesis protein DipZ |
| M. gilvum PYR-GCK | Mflv_0051 | - | 6e-16 | 28.83% (222) | cytochrome c biogenesis protein, transmembrane region |
| M. tuberculosis H37Rv | Rv2874 | dipZ | 0.0 | 68.04% (607) | integral membrane C-type cytochrome biogenesis protein DipZ |
| M. leprae Br4923 | MLBr_02411 | - | 9e-15 | 26.67% (225) | putative cytochrome C-type biogenesis protein |
| M. abscessus ATCC 19977 | MAB_3975c | - | 3e-14 | 27.27% (220) | putative cytochrome C biogenesis protein CcdA |
| M. avium 104 | MAV_4700 | - | 0.0 | 61.29% (589) | DipZ protein |
| M. smegmatis MC2 155 | MSMEG_0972 | - | 3e-15 | 30.93% (236) | cytochrome C biogenesis protein transmembrane region |
| M. thermoresistible (build 8) | TH_2250 | ccsA | 9e-15 | 29.29% (239) | POSSIBLE CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCDA |
| M. ulcerans Agy99 | MUL_2084 | dipZ | 0.0 | 99.66% (583) | integral membrane C-type cytochrome biogenesis protein DipZ |
| M. vanbaalenii PYR-1 | Mvan_0867 | - | 3e-17 | 29.82% (228) | cytochrome c biogenesis protein, transmembrane region |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0051|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0867|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0972|M.smegmatis_MC2_155 --------------------------------------------------
TH_2250|M.thermoresistible__bu --------------------------------------------------
MAB_3975c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_02411|M.leprae_Br4923 --------------------------------------------------
MMAR_1835|M.marinum_M --------------------------------------------------
MUL_2084|M.ulcerans_Agy99 --------------------------------------------------
Mb2899|M.bovis_AF2122/97 MVESRRAAAAASAYASRCGIAPATSQRSLATPPTISVPSGEGRCRCHVAR
Rv2874|M.tuberculosis_H37Rv MVESRRAAAAASAYASRCGIAPATSQRSLATPPTISVPSGEGRCRCHVAR
MAV_4700|M.avium_104 --------------------------------------------------
Mflv_0051|M.gilvum_PYR-GCK -------------------------------------------------M
Mvan_0867|M.vanbaalenii_PYR-1 -------------------------------------------------M
MSMEG_0972|M.smegmatis_MC2_155 --------------------------------------------------
TH_2250|M.thermoresistible__bu --------------------------------------------------
MAB_3975c|M.abscessus_ATCC_199 ---------------------------------------------MILAD
MLBr_02411|M.leprae_Br4923 --------------------------------------------------
MMAR_1835|M.marinum_M -----------------------------------------MRPGQPAAS
MUL_2084|M.ulcerans_Agy99 --------------------------------------------------
Mb2899|M.bovis_AF2122/97 GAGRDPRRRLRRRRWCGRCGYHSHLTGGEFDVNRLCQQRSRERSCQLVAV
Rv2874|M.tuberculosis_H37Rv GAGRDPRRRLRRRRWCGRCGYHSHLTGGEFDVNRLCQQRSRERSCQLVAV
MAV_4700|M.avium_104 --------------------------------------------------
Mflv_0051|M.gilvum_PYR-GCK NVDQIDQLTASGPLLLAMGLAALAGLVSFASPCVVPLVPGYLSYLAAVVG
Mvan_0867|M.vanbaalenii_PYR-1 TLDQIDQLTATGPLLLATGLAALAGLVSFASPCVIPLVPGYLSYLAAVVG
MSMEG_0972|M.smegmatis_MC2_155 -MTGFAEIAAAGPVLLALGVSVLAGLVSFASPCVVPLVPGYLSYLAAVVG
TH_2250|M.thermoresistible__bu -MTGFAELAAAGPVLVAVAISILAGLVSFASPCVVPLVPGYLSYLAAVVG
MAB_3975c|M.abscessus_ATCC_199 AGSAFQDAATSGPLLLALGACALAGLVSFASPCVIPLVPGYLSYLAAVVG
MLBr_02411|M.leprae_Br4923 -MTGFTEIAAAGPLLVALGVCMLAGLVSFVSPCVVPLVPGYLSYLAAVVG
MMAR_1835|M.marinum_M TSHPGPPQFRIVNMVTLALVGFVGGLITGISPCILPVLP--VVFFSGAH-
MUL_2084|M.ulcerans_Agy99 -----------MNMVTLALVGFVGGLITGISPCILPVLP--VVFFSGAH-
Mb2899|M.bovis_AF2122/97 PADPRPKRQRITDVLTLALVGFLGGLITGISPCILPVLP--VIFFSGAQS
Rv2874|M.tuberculosis_H37Rv PADPRPKRQRITDVLTLALVGFLGGLITGISPCILPVLP--VIFFSGAQS
MAV_4700|M.avium_104 -------------MQTIALIGFLGGLITGISPCILPVLP--VILLSGMD-
: :.**:: ***::*::* : ::.
Mflv_0051|M.gilvum_PYR-GCK VDDG-----PAGS---------GAVAVKGARLRVAGAAALFVAGFTVVFL
Mvan_0867|M.vanbaalenii_PYR-1 VDQS-----AAGSA------APGAVAVKGARLRVAGAAGLFVAGFTVVFL
MSMEG_0972|M.smegmatis_MC2_155 VDDD--PVRTGGER----------VALRSARLRVAGAAALFVAGFTVVFL
TH_2250|M.thermoresistible__bu VPKEAAPVVTGGPRRDPPADSGAGMSPRSARLRVTGAAALFVAGFTVVFL
MAB_3975c|M.abscessus_ATCC_199 ADNG----PENGAG------------AQPHRLRVTGSALLFVAGFTAVFL
MLBr_02411|M.leprae_Br4923 VSHE---ETQPGAG--------VIKTPPAARWRVAGSAVLFVAGFTTVFV
MMAR_1835|M.marinum_M -GGATVATTQTGVS-----------TPDPKAARVQTRPYRVIAGLVLSFC
MUL_2084|M.ulcerans_Agy99 -GGATVATTQTGVS-----------TPDPKAARVQTRPYRVIAGLVLSFC
Mb2899|M.bovis_AF2122/97 VDAAQVAKPEGAVA-----------VRRKRALSATLRPYRVIGGLVLSFG
Rv2874|M.tuberculosis_H37Rv VDAAQVAKPEGAVA-----------VRRKRALSATLRPYRVIGGLVLSFG
MAV_4700|M.avium_104 --------------------------GDRRGVGSAARPYLVIAGLVCSFS
. .:.*:. *
Mflv_0051|M.gilvum_PYR-GCK LGTVAVLGMTTTLITNQLLLQRIG--GVITILMGLVFIGLVPVLQRDTRF
Mvan_0867|M.vanbaalenii_PYR-1 LGTVAVLGMTTALITNQLLLQRLG--GVVTILMGLVFIGLVPVLQRDTRF
MSMEG_0972|M.smegmatis_MC2_155 LGAVAVLGMTTTLIANQLLLQRIG--GVVTIVMGLVFVGFIPALQRQARF
TH_2250|M.thermoresistible__bu LGTVAVLGMTTTLITNQVLLQRIG--GVITIVMGLVFIGFIPALQRQARF
MAB_3975c|M.abscessus_ATCC_199 LGTVAVMGMTTSLITNQVLLQRIG--GVVTIAMGLVFIGLVPALQRDIRF
MLBr_02411|M.leprae_Br4923 LDTVAVLGMTTVLTTHQVLLQRVG--GVLTIVMGLVFVGLLPALQRQVQF
MMAR_1835|M.marinum_M LVTLTGSALLSLLHLRQDTIRWVALAALVAIGLGLIFPRLEQWLQRPFSR
MUL_2084|M.ulcerans_Agy99 LVTLTGSALLSLLHLRQDTIRWVALAALVAIGLGLIFPRLEQWLQRPFSR
Mb2899|M.bovis_AF2122/97 MVTLLGSALLSVLHLPQDAIRWAALVALVAIGAGLIFPRFEQLLEKPFSR
Rv2874|M.tuberculosis_H37Rv MVTLLGSALLSVLHLPQDAIRWAALVALVAIGAGLIFPRFEQLLEKPFSR
MAV_4700|M.avium_104 VATLIGSALLTALHLPQDAIRWTALVVLTAIGLGLIFPPLQQLIERPFAY
: :: .: : * * :: . : :* **:* : :::
Mflv_0051|M.gilvum_PYR-GCK TPRRISTVGGAPL-LGAVFALGWTPCLGPTLTGVIAVASATEGSNVARGV
Mvan_0867|M.vanbaalenii_PYR-1 TPRQISTLGGAPL-LGAVFALGWTPCLGPTLTGVIAVASATEGSNVARGV
MSMEG_0972|M.smegmatis_MC2_155 TPRQLSTVAGAPL-LGAVFALGWTPCLGPTLTGVIAVASATDGATVARGV
TH_2250|M.thermoresistible__bu APRQWSTVAGAPL-LGAVFALGWTPCLGPTLTGVITVASATDGASVARGV
MAB_3975c|M.abscessus_ATCC_199 TPRRVSTVAGAPL-LGAVFALGWTPCLGPTLTGVVAVASATEGADVARGI
MLBr_02411|M.leprae_Br4923 SLRQLTTVAGAPV-LGTVFALGWTPCLGPTLSGVITVAAATDGVNVTRGI
MMAR_1835|M.marinum_M IPHNSISAGGTGFGLGLALGVLYVPCAGPVLTAIILAGATSRIG--LNTV
MUL_2084|M.ulcerans_Agy99 IPHNSISAGGTGFGLGLALGVLYVPCAGPVLTAIILAGATSRIG--LNTV
Mb2899|M.bovis_AF2122/97 IPQKQIVTRSNGFGLGLALGVLYVPCAGPILAAIVVAGATATIG--LGTV
Rv2874|M.tuberculosis_H37Rv IPQKQIVTRSNGFGLGLALGVLYVPCAGPILAAIVVAGATATIG--LGTV
MAV_4700|M.avium_104 LPQRQSRPGADGFGLGLTLGALYVPCAGPVLAAIVVAGGTSSIG--PGAL
:. . . ** .:. :.** ** *:.:: ...:: :
Mflv_0051|M.gilvum_PYR-GCK VLVIAYCLGLGIPFVLLAFGSARAVAGLGWLRRNTRTIQILGGVLMILVG
Mvan_0867|M.vanbaalenii_PYR-1 VLVIAYCLGLGIPFVLLAFGSARAVAGLGWLRRHTRTIQVLGGVLMILVG
MSMEG_0972|M.smegmatis_MC2_155 VLVLAYCLGLGIPFVLLALGSARAVQGLGWLRRHTRTIQIFGGVLLILVG
TH_2250|M.thermoresistible__bu VLVIAYCLGLGIPFILLAFGSARAVQGLGWLRRNTRTIQIFGGVLLILVG
MAB_3975c|M.abscessus_ATCC_199 ALVIAYCLGLGMPFLLLAFGSARAVRGMDWLRRHTRMIQVIGGIALLAVG
MLBr_02411|M.leprae_Br4923 LLVIAYCMGLGIPFVLLASGSAQAVAGLRWLRQYGRAIQVFGGMLLIAIG
MMAR_1835|M.marinum_M VLTCAFALGTALPLLFFALAGRETAGRVSAFRRRQREIRIGAGVVTILLA
MUL_2084|M.ulcerans_Agy99 VLTCAFALGTALPLLFFALAGRETAGRVSAFRRRQHEIRIGAGVVTILLA
Mb2899|M.bovis_AF2122/97 VLTATFALGAALPLLFFALAGQRIAERVGAFRRRQREIRIATGSVTILLA
Rv2874|M.tuberculosis_H37Rv VLTATFALGAALPLLFFALAGQRIAERVGAFRRRQREIRIATGSVTILLA
MAV_4700|M.avium_104 VLTATFAAGNALPLLAFALAGRRVAQRVAAFRRRQRAIQVAGGIAMIVLA
*. ::. * .:*:: :* .. . . : :*: : *:: * : :.
Mflv_0051|M.gilvum_PYR-GCK AALVTGLWNEFVSWVRDAFVSDVRLPI-----------------------
Mvan_0867|M.vanbaalenii_PYR-1 AALVTGLWNDFVSWIRDAFVSDVRLPI-----------------------
MSMEG_0972|M.smegmatis_MC2_155 AALVTGLWNEFVSYVRDAFVSDVRLPI-----------------------
TH_2250|M.thermoresistible__bu AALVTGLWNEFISWVRDAFVSDVRLPI-----------------------
MAB_3975c|M.abscessus_ATCC_199 VALITGVWADFVAWVRDSFVSDARLPI-----------------------
MLBr_02411|M.leprae_Br4923 AALIAGVWDDFVSWLRDAVVSDMRVSI-----------------------
MMAR_1835|M.marinum_M VALVLNLPATLQRAIPDYTSALQGLP---------EQVGGPNQIGTNLGG
MUL_2084|M.ulcerans_Agy99 VALVLNLPATLQRAIPDYTSALQGLP---------EQVGGPNQIGTNLGG
Mb2899|M.bovis_AF2122/97 VALVFDLPAALQRAIPDYTASLQ------------QQISTGTEIREQLN-
Rv2874|M.tuberculosis_H37Rv VALVFDLPAALQRAIPDYTASLQ------------QQISTGTEIREQLN-
MAV_4700|M.avium_104 VALVFNLPAMLQRAVPDYTTAMQNRLGANDLQRSLSPPGPPPTQGGALQL
.**: .: : : * :
Mflv_0051|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0867|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0972|M.smegmatis_MC2_155 --------------------------------------------------
TH_2250|M.thermoresistible__bu --------------------------------------------------
MAB_3975c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_02411|M.leprae_Br4923 --------------------------------------------------
MMAR_1835|M.marinum_M IGGLVTDQNAQLSNCTNGAAQPQDCGSAPDITGISGWLNTPEHQPIRLSS
MUL_2084|M.ulcerans_Agy99 IGGLVTDQNAQLSNCTNGAAQPQDCGSAPDITGISGWLNTPEHQPIRLSS
Mb2899|M.bovis_AF2122/97 LGGIVNAQNAQLSNCSDGAAQLESCGTAPDLKGITGWLNTPGNKPIDLKS
Rv2874|M.tuberculosis_H37Rv LGGIVNAQNAQLSNCSDGAAQLESCGTAPDLKGITGWLNTPGNKPIDLKS
MAV_4700|M.avium_104 SPGDVTGG-GALSDCSDGLAELQRCGPAPALTGITGWLNTPDGKPLDPAA
Mflv_0051|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0867|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0972|M.smegmatis_MC2_155 --------------------------------------------------
TH_2250|M.thermoresistible__bu --------------------------------------------------
MAB_3975c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_02411|M.leprae_Br4923 --------------------------------------------------
MMAR_1835|M.marinum_M LRGRVVLVDFWAYSCINCQRAIPHVVGWYRAYKDSGLEVIGVHTPEYAFE
MUL_2084|M.ulcerans_Agy99 LRGRVVLVDFWAYSCINCQRAIPHVVGWYRAYKDSGLEVIGVHTPEYAFE
Mb2899|M.bovis_AF2122/97 LRGKVVLIDFWAYSCINCQRAIPHVVGWYQAYKDSGLAVIGVHTPEYAFE
Rv2874|M.tuberculosis_H37Rv LRGKVVLIDFWAYSCINCQRAIPHVVGWYQAYKDSGLAVIGVHTPEYAFE
MAV_4700|M.avium_104 VRGKVILIDFWAYSCINCQRAIPHVIDWYDRYHDSGFLVIGVHTPEYAFE
Mflv_0051|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0867|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0972|M.smegmatis_MC2_155 --------------------------------------------------
TH_2250|M.thermoresistible__bu --------------------------------------------------
MAB_3975c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_02411|M.leprae_Br4923 --------------------------------------------------
MMAR_1835|M.marinum_M KVPENVAAGAADLNITYPIALDNNYSTWTNYRNAYWPAEYLIDASGTVRH
MUL_2084|M.ulcerans_Agy99 KVPENVAAGAADLNITYPIALDNNYSTWTNYRNAYWPAEYLIDASGTVRH
Mb2899|M.bovis_AF2122/97 KVPGNVAKGAANLGISYPIALDNNYATWTNYRNRYWPAEYLIDATGTVRH
Rv2874|M.tuberculosis_H37Rv KVPGNVAKGAANLGISYPIALDNNYATWTNYRNRYWPAEYLIDATGTVRH
MAV_4700|M.avium_104 RVPGNVASGAADLHIGYPIALDNDYATWNNYQNLYWPAEYLIDATGQVRH
Mflv_0051|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0867|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0972|M.smegmatis_MC2_155 --------------------------------------------------
TH_2250|M.thermoresistible__bu --------------------------------------------------
MAB_3975c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_02411|M.leprae_Br4923 --------------------------------------------------
MMAR_1835|M.marinum_M IKFGEGDYDGTENLIRRLLTDANPGAKLPAP--VDAADTTPALSLTPETY
MUL_2084|M.ulcerans_Agy99 IKFGEGDYDGTENLIRRLLTDANPGAKLPAP--VDAADTTPALSLTPETY
Mb2899|M.bovis_AF2122/97 IKFGEGDYNVTETLVRQLLNDAKPGVKLPQPSSTTTPDLTPRAALTPETY
Rv2874|M.tuberculosis_H37Rv IKFGEGDYNVTETLVRQLLNDAKPGVKLPQPSSTTTPDLTPRAALTPETY
MAV_4700|M.avium_104 TKFGEGDYDGTERLIRELLAAAHPGARLPAP--ANTADTTPQSRLTPETY
Mflv_0051|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0867|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0972|M.smegmatis_MC2_155 --------------------------------------------------
TH_2250|M.thermoresistible__bu --------------------------------------------------
MAB_3975c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_02411|M.leprae_Br4923 --------------------------------------------------
MMAR_1835|M.marinum_M FGVGKAVNFAGSG-YDQGSATFSYPLALPPDTFALQGPWSLDHQRATADG
MUL_2084|M.ulcerans_Agy99 FGVGKAVTFAGSG-YDQGSATFSYPLALPPDTFALQGPWSLDHQRATADG
Mb2899|M.bovis_AF2122/97 FGVGKVVNYGGGGAYDEGSAVFDYPPSLAANSFALRGRWALDYQGATSDG
Rv2874|M.tuberculosis_H37Rv FGVGKVVNYGGGGAYDEGSAVFDYPPSLAANSFALRGRWALDYQGATSDG
MAV_4700|M.avium_104 LGVGKAGNYGGTGDYRSGTATLSYPATLGEDRFALRGRWTLDDQGATAAG
Mflv_0051|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0867|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0972|M.smegmatis_MC2_155 --------------------------------------------------
TH_2250|M.thermoresistible__bu --------------------------------------------------
MAB_3975c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_02411|M.leprae_Br4923 --------------------------------------------------
MMAR_1835|M.marinum_M DDCRIKLNYLAKNVYLVVGGTGTLTVTGAGKSTTLRIGGAPTSHQIVAGD
MUL_2084|M.ulcerans_Agy99 DDCRIKLNYLAKNVYLVVGGTGTLTVTGAGKSTTLRIGGAPTSHQIVAGD
Mb2899|M.bovis_AF2122/97 NDAAIKLNYHAKDVYIVVGGTGTLTVVRDGKPATLPISGPPTTHQVVAGD
Rv2874|M.tuberculosis_H37Rv NDAAIKLNYHAKDVYIVVGGTGTLTVVRDGKPATLPISGPPTTHQVVAGY
MAV_4700|M.avium_104 DDCAVRLNYTAKDVYAVVGGTGTLTVTRDGTTTTTPIGGAPTLHRIVADD
Mflv_0051|M.gilvum_PYR-GCK -----------------------
Mvan_0867|M.vanbaalenii_PYR-1 -----------------------
MSMEG_0972|M.smegmatis_MC2_155 -----------------------
TH_2250|M.thermoresistible__bu -----------------------
MAB_3975c|M.abscessus_ATCC_199 -----------------------
MLBr_02411|M.leprae_Br4923 -----------------------
MMAR_1835|M.marinum_M QVQRTTIEVHPSKGLQVYSFTYG
MUL_2084|M.ulcerans_Agy99 QVQRTTIEVHPSKGLQVYSFTYG
Mb2899|M.bovis_AF2122/97 RLASETLEVRPSKGLQVFSFTYG
Rv2874|M.tuberculosis_H37Rv RLASETLEVRPSKGLQVFSFTYG
MAV_4700|M.avium_104 SAHRDQLDMRVSPGLQVFSFTFG