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M. marinum M MMAR_1126 (groEL)

annotation: 60 kDa chaperone (GroEL1)
coordinates: 1349333 - 1350952
length: 539

MSKLIEYDETARRAMEAGVDKLADTVRVTLGPRGRHVVLAKSFGGPTVTNDGVTVARDIDLEDPFENLGA
QLVKSVATKTNDVAGDGTTTATVLAQALVKTGLRLVAAGINPIALGSGIGKAADAVSEALLASATPVSGK
DAIAQVATVSSRDQLIGDLVGEAMSKVGHDGVVSVEESSTLGTELEFTEGVGFDKGYLSAYFVTDFDAQQ
AVLEDPLILLHQDKISSLPDLLPLLEKVAESGKPLMIIAEDIEGEALATLVVNSIRKTLKAIAVKSPYFG
DRRKAFLQDLAAVTGAEVVNPDAGLVLREVGLEVMGSARRVVVSKDDTIIVDGGGAPEAVEARVNLLRSE
IDRSDSEWDREKLGERLAKLAGGVAVIKVGAATETELKKRKESVEDAVAAAKAAVEEGIVAGGGSALIQA
RNALKDLRASLSGDEAVGVDVFSEALAAPLYWIATNAGLDGSVVVNKVSELPAGHGLNAATLTYGDLAAD
GIVDPVKVTRSAVLNASSVARMVLTTETAIVDKPAEPEDDGHGHHGHAH
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_1126groEL-100% (539)60 kDa chaperone (GroEL1)
M. marinum MMMAR_0759groELe-17960.85% (539) 60 kDa chaperonin 2 GroEL2

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3451cgroEL0.087.04% (540) chaperonin GroEL
M. gilvum PYR-GCKMflv_4924groEL0.081.11% (540) chaperonin GroEL
M. tuberculosis H37RvRv3417cgroEL0.087.04% (540) chaperonin GroEL
M. leprae Br4923MLBr_00381groEL0.083.67% (539) chaperonin GroEL
M. abscessus ATCC 19977MAB_3731c-0.079.22% (539) 60 kDa chaperonin 1 (GroEL protein 1)
M. avium 104MAV_4365groEL0.085.13% (538) chaperonin GroEL
M. smegmatis MC2 155MSMEG_1583groEL0.081.67% (540) chaperonin GroEL
M. thermoresistible (build 8)TH_1687groEL10.079.59% (539) 60 KDA CHAPERONIN 1 GROEL1 (PROTEIN CPN60-1) (GROEL
M. ulcerans Agy99MUL_0886groEL0.099.44% (539) chaperonin GroEL
M. vanbaalenii PYR-1Mvan_1495groEL0.080.33% (544) chaperonin GroEL

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1126|M.marinum_M               MSKLIEYDETARRAMEAGVDKLADTVRVTLGPRGRHVVLAKSFGGPTVTN
MUL_0886|M.ulcerans_Agy99           MSKLIEYDETARRAMEAGVDKLAETVRVTLGPRGRHVVLAKSFGGPTVTN
Mb3451c|M.bovis_AF2122/97           MSKLIEYDETARRAMEVGMDKLADTVRVTLGPRGRHVVLAKAFGGPTVTN
Rv3417c|M.tuberculosis_H37Rv        MSKLIEYDETARRAMEVGMDKLADTVRVTLGPRGRHVVLAKAFGGPTVTN
MLBr_00381|M.leprae_Br4923          MSKLIEYDETARHAMEVGMNKLADTVRVTLGPRGRHVVLAKAFGGPTITN
MAV_4365|M.avium_104                MSKIIEYDETARRAIEAGVNTLADAVRVTLGPRGRHVVLAKAFGGPAVTN
Mflv_4924|M.gilvum_PYR-GCK          MSKQIEFNETARRAMEAGVDKLADAVKVTLGPRGRHVVLAKSWGGPTVTN
Mvan_1495|M.vanbaalenii_PYR-1       MSKQIEFNETARRAMEIGVDKLADAVKVTLGPRGRHVVLAKSWGGPTVTN
MSMEG_1583|M.smegmatis_MC2_155      MSKQIEFNETARRAMEAGVDKLADAVKVTLGPRGRHVVLAKSFGGPQVTN
TH_1687|M.thermoresistible__bu      MSKLIEYNEIARRALETGVDKLADAVKVTLGPRGRHVVLAKAFGGPQVTN
MAB_3731c|M.abscessus_ATCC_199      MSKLIEFNETARRALEAGVNKLADAVKVTLGPRGRHVVLAKAFGGPAVTN
                                    *** **::* **:*:* *::.**::*:**************::*** :**

MMAR_1126|M.marinum_M               DGVTVARDIDLEDPFENLGAQLVKSVATKTNDVAGDGTTTATVLAQALVK
MUL_0886|M.ulcerans_Agy99           DGVTVARDIDLEDPFENLGAQLVKSVATKTNDVAGDGTTTATVLARALVK
Mb3451c|M.bovis_AF2122/97           DGVTVAREIELEDPFEDLGAQLVKSVATKTNDVAGDGTTTATILAQALIK
Rv3417c|M.tuberculosis_H37Rv        DGVTVAREIELEDPFEDLGAQLVKSVATKTNDVAGDGTTTATILAQALIK
MLBr_00381|M.leprae_Br4923          DGVTVAREIDLEDPFENLGAQLVKSVATKTNDVAGDGTTTATVLAQALVK
MAV_4365|M.avium_104                DGVTVAREIDLEDPFENLGAQLVKSVATKTNDVAGDGTTTATVLAQALVK
Mflv_4924|M.gilvum_PYR-GCK          DGVTIAREIDLEDPFENLGAQLVKSVATKTNDVAGDGTTTATVLAQALVK
Mvan_1495|M.vanbaalenii_PYR-1       DGVTIAREIDLEDPFENLGAQLVKSVATKTNDVAGDGTTTATVLAQAIIK
MSMEG_1583|M.smegmatis_MC2_155      DGVTIAREIDLEDPYENLGAQLVKSVATKTNDVAGDGTTTATVLAQALVR
TH_1687|M.thermoresistible__bu      DGVTIAREIELEDPFENLGAQLVKSVATKTNDIAGDGTTTATVLAQALVQ
MAB_3731c|M.abscessus_ATCC_199      DGVTIARDIDLEDPFENLGAQLVKSVATKTNDVAGDGTTTATVLAQALVR
                                    ****:**:*:****:*:***************:*********:**:*:::

MMAR_1126|M.marinum_M               TGLRLVAAGINPIALGSGIGKAADAVSEALLASATPVSGKDAIAQVATVS
MUL_0886|M.ulcerans_Agy99           TGLRLVAAGINPIALGSGIGKAADAVSEALLASATPVSGKDAIAQVATVS
Mb3451c|M.bovis_AF2122/97           GGLRLVAAGVNPIALGVGIGKAADAVSEALLASATPVSGKTGIAQVATVS
Rv3417c|M.tuberculosis_H37Rv        GGLRLVAAGVNPIALGVGIGKAADAVSEALLASATPVSGKTGIAQVATVS
MLBr_00381|M.leprae_Br4923          GGLRMVAAGANPVALGAGISKAADAVSEALLAVATPVAGKDAITQVATVS
MAV_4365|M.avium_104                GGLRLVAAGANPIELGAGISKAADAVSEALLASATTVSGKDAIAQVATVS
Mflv_4924|M.gilvum_PYR-GCK          AGLRNVAAGANPIALGAGIAKAADAVSEALLASATPVKDAKSIGQVATVS
Mvan_1495|M.vanbaalenii_PYR-1       GGLRNVAAGANPIALGAGISKAADAVSEALLAGATPVTDKKSIAQVATVS
MSMEG_1583|M.smegmatis_MC2_155      AGLRNVAAGANPIALGSGISKAADAVSEALLASATPVDDKKAIAQVATVS
TH_1687|M.thermoresistible__bu      AGLKNVAAGANPLALGSGIAKAADAVGEALLAAATPVKDRSAIAQVATVS
MAB_3731c|M.abscessus_ATCC_199      AGLRNVAAGANPIALGAGISRAADAVSERLLTVAAPVAGEHAIAQVATVS
                                     **: **** **: ** **.:*****.* **: *:.* .  .* ******

MMAR_1126|M.marinum_M               SRDQLIGDLVGEAMSKVGHDGVVSVEESSTLGTELEFTEGVGFDKGYLSA
MUL_0886|M.ulcerans_Agy99           SRDQLIGDLVGEAMSKVGHDGVVSVEESSTLGTELEFTEGVGFDKGYLSA
Mb3451c|M.bovis_AF2122/97           SRDEQIGDLVGEAMSKVGHDGVVSVEESSTLGTELEFTEGIGFDKGFLSA
Rv3417c|M.tuberculosis_H37Rv        SRDEQIGDLVGEAMSKVGHDGVVSVEESSTLGTELEFTEGIGFDKGFLSA
MLBr_00381|M.leprae_Br4923          SRDEQIGALVGEGMNKVGTDGVVSVEESSTLDTELEFTEGVGFDKGFLSA
MAV_4365|M.avium_104                SRDQVLGELVGEAMTKVGVDGVVSVEESSTLNTELEFTEGVGFDKGFLSA
Mflv_4924|M.gilvum_PYR-GCK          SRDELVGELVGEAMTKVGTDGVVTVEESSTLNTELEVTEGVGFDKGFISA
Mvan_1495|M.vanbaalenii_PYR-1       SRDEEVGELVGEAMTRVGHDGVVTVEESSTLLTELEITEGVGFDKGFLSA
MSMEG_1583|M.smegmatis_MC2_155      SRDEQVGELVGEAMTKVGHDGVVTVEESSTLETYLEVTEGVGFDKGFLSA
TH_1687|M.thermoresistible__bu      SRDPEIGEMVAEAMTRVGHDGVVTVEESSTLDTEVEITEGVGFDKGYLSA
MAB_3731c|M.abscessus_ATCC_199      SRDPEIGELVGEAMTKVGGDGVVSVEESSTINTELVITDGVQFDKGYLSQ
                                    ***  :* :*.*.*.:** ****:******: * : .*:*: ****::* 

MMAR_1126|M.marinum_M               YFVTDFDAQQAVLEDPLILLHQDKISSLPDLLPLLEKVAESGKPLMIIAE
MUL_0886|M.ulcerans_Agy99           YFVTDFDAQQAVLEDPLILLHQDKISSLPDLLPLLEKVAESGKPLMIIAE
Mb3451c|M.bovis_AF2122/97           YFVTDFDNQQAVLEDALILLHQDKISSLPDLLPLLEKVAGTGKPLLIVAE
Rv3417c|M.tuberculosis_H37Rv        YFVTDFDNQQAVLEDALILLHQDKISSLPDLLPLLEKVAGTGKPLLIVAE
MLBr_00381|M.leprae_Br4923          YFVTDFDSQQAVLDDPLVLLHQEKISSLPELLPMLEKVTESGKPLLIVAE
MAV_4365|M.avium_104                YFVTDFDAQQAVLDDPVILLHQEKISSLPDLLPMLEKVAESGKPLLIIAE
Mflv_4924|M.gilvum_PYR-GCK          YFVTDFDSQEAVLEDALVLLHREKISSLPDLLPLLEKVAEAGKPLLIVAE
Mvan_1495|M.vanbaalenii_PYR-1       YFVTDFDSQEAVLEDALVLLHREKISSLPDLLPLLEKVAEAGKPLLIIAE
MSMEG_1583|M.smegmatis_MC2_155      YFVTDFDSQEAVLEDALVLLHRDKISSLPDLLPLLEKVAEAGKPLLIVAE
TH_1687|M.thermoresistible__bu      YFVTDFDTQQAVLEDAYVLLHREKISSLPDLLPLLEKVAESGKPLLVIAE
MAB_3731c|M.abscessus_ATCC_199      YFVTDFDDQKAVLEDALVLLHRDKISSLPDLLPLLELVAKEGKPLLIVAE
                                    ******* *:***:*. :***::******:***:** *:  ****:::**

MMAR_1126|M.marinum_M               DIEGEALATLVVNSIRKTLKAIAVKSPYFGDRRKAFLQDLAAVTGAEVVN
MUL_0886|M.ulcerans_Agy99           DIEGEALATLVVNSIRKTLKAIAVKSPYFGDRRKAFLQDLAAVTGAEVVN
Mb3451c|M.bovis_AF2122/97           DVEGEALATLVVNAIRKTLKAVAVKGPYFGDRRKAFLEDLAVVTGGQVVN
Rv3417c|M.tuberculosis_H37Rv        DVEGEALATLVVNAIRKTLKAVAVKGPYFGDRRKAFLEDLAVVTGGQVVN
MLBr_00381|M.leprae_Br4923          DLEGEALATLVVNSIRKTLKAVAVKSPFFGDRRKAFLEDLAIVTGGQVVN
MAV_4365|M.avium_104                DIEGEALATLVVNSIRKTLKAVAVKAPFFGDRRKAFLEDLAIVTGGQVIN
Mflv_4924|M.gilvum_PYR-GCK          DVEGEALSTLVVNAIRKTLKAVAVKAPFFGDRRKAFLDDLAVVTGGQVVN
Mvan_1495|M.vanbaalenii_PYR-1       DVEGEALSTLVVNAIRKTLKAVAVKAPFFGDRRKAFLDDLAVVTGGQVVN
MSMEG_1583|M.smegmatis_MC2_155      DVEGEALSTLVVNAIRKTLKAVAVKAPFFGDRRKAFLDDLAIVTGGQVVN
TH_1687|M.thermoresistible__bu      DVEGEALSTLVVNAIRKTLKAVAVKAPFFGDRRKAFLEDLAIVTGGQVVN
MAB_3731c|M.abscessus_ATCC_199      DVEGEPLSTLVVNAIRKTLKAVAVKAPFFGDRRKAFLEDLAIVTNAQVVN
                                    *:***.*:*****:*******:***.*:*********:*** **..:*:*

MMAR_1126|M.marinum_M               PDAGLVLREVGLEVMGSARRVVVSKDDTIIVDGGGAPEAVEARVNLLRSE
MUL_0886|M.ulcerans_Agy99           PDAGLVLREVGLEVMGSARRVVVSKDDTIIVDGGGAPEAVEARVNLLRSE
Mb3451c|M.bovis_AF2122/97           PDAGMVLREVGLEVLGSARRVVVSKDDTVIVDGGGTAEAVANRAKHLRAE
Rv3417c|M.tuberculosis_H37Rv        PDAGMVLREVGLEVLGSARRVVVSKDDTVIVDGGGTAEAVANRAKHLRAE
MLBr_00381|M.leprae_Br4923          PETGLVLREVGTDVLGSARRVVVSKDDTIIVDGGGSNDAVAKRVNQLRAE
MAV_4365|M.avium_104                PDTGLLLREVGTEVLGSARRVVVSKDDTIIVDGGGAKDAVANRIKQLRAE
Mflv_4924|M.gilvum_PYR-GCK          PDVGLVLREVGLEVLGTARRVVVDKDSTVIVDGGGTQDAIEGRKGQLRAE
Mvan_1495|M.vanbaalenii_PYR-1       PDVGLVLRDVGLDVLGTARRVVVDKDSTVIVDGGGTQEAIEGRKAQLRAE
MSMEG_1583|M.smegmatis_MC2_155      PDVGLLLREVGLEVLGSARRVVVNKDSTVIVDGGGTAEAIADRVKQIKSE
TH_1687|M.thermoresistible__bu      PDVGLVLREVGLEVLGTARRVVVTKDDTVIVDGGGTKEAIAERAAQLRKE
MAB_3731c|M.abscessus_ATCC_199      PDVGLSLREVGIEVLGTARRVVVSKDETVIVDGGGSEDAIKARVAQLKAE
                                    *:.*: **:** :*:*:****** **.*:******: :*:  *   :: *

MMAR_1126|M.marinum_M               IDRSDSEWDREKLGERLAKLAGGVAVIKVGAATETELKKRKESVEDAVAA
MUL_0886|M.ulcerans_Agy99           IDRSDSEWDREKLGERLAKLAGGVAVIKVGAATETELKKRKESVEDAVAA
Mb3451c|M.bovis_AF2122/97           IDKSDSDWDREKLGERLAKLAGGVAVIKVGAATETALKERKESVEDAVAA
Rv3417c|M.tuberculosis_H37Rv        IDKSDSDWDREKLGERLAKLAGGVAVIKVGAATETALKERKESVEDAVAA
MLBr_00381|M.leprae_Br4923          IEVSDSEWDREKLQERVAKLAGGVAVIKVGAVTETALKKRKESVEDAVAA
MAV_4365|M.avium_104                IEKTDSDWDREKLQERLAKLAGGVAVIKVGAATETALKERKESVEDAVAA
Mflv_4924|M.gilvum_PYR-GCK          IEVSDSDWDREKLEERLAKLAGGVAVIKVGAATETDLKKRKEAVEDAVAA
Mvan_1495|M.vanbaalenii_PYR-1       IEASDSDWDREKLEERLAKLAGGVAVIKVGAATETDLKKRKEAVEDAVHA
MSMEG_1583|M.smegmatis_MC2_155      IETTDSDWDREKLQERLAKLAGGVAVIKVGAATETDLKKRKEAVEDAVAA
TH_1687|M.thermoresistible__bu      IETTDSDWDREKLEERLAKLAGGVAVIKVGAATETALKERKESVEDAVAA
MAB_3731c|M.abscessus_ATCC_199      IETTDSDWDREKLQERLAKLAGGVAVIKVGAPTDTALKERKHRVEDAVSA
                                    *: :**:****** **:************** *:* **:**. ***** *

MMAR_1126|M.marinum_M               AKAAVEEGIVAGGGSALI-QARNALKDLRASLSGDEAVGVDVFSEALAAP
MUL_0886|M.ulcerans_Agy99           AKAAVEEGIVAGGGSALI-QARNALKDLRASLSGDEAVGVDVFSEALAAP
Mb3451c|M.bovis_AF2122/97           AKAAVEEGIVPGGGASLIHQARKALTELRASLTGDEVLGVDVFSEALAAP
Rv3417c|M.tuberculosis_H37Rv        AKAAVEEGIVPGGGASLIHQARKALTELRASLTGDEVLGVDVFSEALAAP
MLBr_00381|M.leprae_Br4923          AKASIEEGIIAGGGSALV-QCGAALKQLRTSLTGDEALGIDVFFEALKAP
MAV_4365|M.avium_104                AKAAVEEGIVAGGGSALL-QARKALDELRGSLSGDQALGVDVFAEALGAP
Mflv_4924|M.gilvum_PYR-GCK          AKAAVEEGIVIGGGAALV-HAGSALDSLRSELKGDELLGVEVFASALSSP
Mvan_1495|M.vanbaalenii_PYR-1       AKAAVEEGIVVGGGAALV-QAGAGLAKLRSELSGDEALGVEVFTAALSSP
MSMEG_1583|M.smegmatis_MC2_155      AKAAVEEGIVTGGGAALV-QARSAVEKLRGELSGDEALGVDVFASALSAP
TH_1687|M.thermoresistible__bu      AKAAVEEGVVVGGGVALL-QVRPALDKLRDSLSGDEALGVSIFAEALSAP
MAB_3731c|M.abscessus_ATCC_199      AKAAVEEGIVAGGGSALV-QARSALDGLRAELKGDEAKGVDVFEAALSAP
                                    ***::***:: *** :*: :   .:  ** .*.**:  *:.:*  ** :*

MMAR_1126|M.marinum_M               LYWIATNAGLDGSVVVNKVSELPAGHGLNAATLTYGDLAADGIVDPVKVT
MUL_0886|M.ulcerans_Agy99           LYWIATNAGLDGSVVVNKVSEVPAGHGLNAATLTYGDLAADGIVDPVKVT
Mb3451c|M.bovis_AF2122/97           LFWIAANAGLDGSVVVNKVSELPAGHGLNVNTLSYGDLAADGVIDPVKVT
Rv3417c|M.tuberculosis_H37Rv        LFWIAANAGLDGSVVVNKVSELPAGHGLNVNTLSYGDLAADGVIDPVKVT
MLBr_00381|M.leprae_Br4923          LYWIATNAGLDGAVVVDKVSGLPAGHGLNASTLGYGDLVADGVVDPVKVT
MAV_4365|M.avium_104                LYWIASNAGLDGAVAVHKVAELPAGHGLNAEKLSYGDLIADGVIDPVKVT
Mflv_4924|M.gilvum_PYR-GCK          LYWIATNAGLDGAVVVNKVSELPAGQGFNAATLEYGDLIGDGVIDPVKVT
Mvan_1495|M.vanbaalenii_PYR-1       LYWIATNAGLDGAVVVNKVSELPAGQGFNAATLEYGDLIADGVIDPVKVT
MSMEG_1583|M.smegmatis_MC2_155      LYWIATNAGLDGSVVVNKVSELPKGQGFNAATLEFGDLVSAGVVDPAKVT
TH_1687|M.thermoresistible__bu      LYWIATNAGLDGSVVVAKVAEMPDNHGFNAATLSYGDLMADGVIDPAKVT
MAB_3731c|M.abscessus_ATCC_199      LFWIATNAGLDGAVVVSKVAELDAGHGFNAATLEYGDLIADGVIDPVKVT
                                    *:***:******:*.* **: :  .:*:*. .* :*** . *::**.***

MMAR_1126|M.marinum_M               RSAVLNASSVARMVLTTETAIVDKPAEPEDDGHGH-HGHAH----
MUL_0886|M.ulcerans_Agy99           RSAVLNASSVARMVLTTETAIVDKPAEPEDDGHGH-HGHAH----
Mb3451c|M.bovis_AF2122/97           RSAVLNASSVARMVLTTETVVVDKPAKAEDHDH-H-HGHAH----
Rv3417c|M.tuberculosis_H37Rv        RSAVLNASSVARMVLTTETVVVDKPAKAEDHDH-H-HGHAH----
MLBr_00381|M.leprae_Br4923          RSAVLNAASVARMMLTTETAVVDKPAKTEEHDH---HGHAH----
MAV_4365|M.avium_104                RSAVLNSASVARMVLTTETAVVDKPAEEADDHG---HGHHHH---
Mflv_4924|M.gilvum_PYR-GCK          RSAVVNAASVARMVLTTETAVVEKPAEAEDDGHGHGHGHHHH---
Mvan_1495|M.vanbaalenii_PYR-1       RSAVVNAASVARMILTTETAVVEKPEESEDDGHGHGHGHHHGHAH
MSMEG_1583|M.smegmatis_MC2_155      RSAVLNAASVARMILTTETAVVDKPADEDEHGHGHHHGHAH----
TH_1687|M.thermoresistible__bu      RTAVLNAASVARMVLTTETAVVEKPEEEQDD---HGHGHVH----
MAB_3731c|M.abscessus_ATCC_199      RSAVINAASAARMILTTETSIVDKPAEEADHGHGH-HGHAH----
                                    *:**:*::*.***:***** :*:** .  :.     *** *