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M. marinum M MMAR_0899 (menC)

annotation: muconate cycloisomerase, MenC
coordinates: 1090655 - 1091638
length: 327

VIPGPATLPDLLDRLHVVALPMRVRFRGITTREVALIEGPSGWGEFGAFLEYQPPEAAAWLASAIDAAYG
QPPPVRRGRIPINATVPAVPPAQVPELLARFPGARTAKVKVAEPGQTLASDVERVNAVRALVPTVRVDAN
GGWSVDQAAQAAVALTADGPLEYLEQPCATVGELAELRRRIEVPIAADEAIRKAEDPLAVVRAGAADVAV
LKVAPLGGVWALLDIAAQIDIPVVISSALDSAVGIAAGLSAAAALPQLQHACGLGTGGLFVEDVAEPAIP
VDGALAPQRVVPDPARLRALGAAPDRRQWWIDRIKACYPLLYRRSGD
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_0899menC-100% (327)muconate cycloisomerase, MenC

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0568menC1e-14681.00% (321) O-succinylbenzoate synthase
M. gilvum PYR-GCKMflv_5268-1e-13876.58% (316) O-succinylbenzoate synthase
M. tuberculosis H37RvRv0553menC1e-14681.00% (321) O-succinylbenzoate synthase
M. leprae Br4923MLBr_02268-1e-14378.29% (327) O-succinylbenzoate synthase
M. abscessus ATCC 19977MAB_3935c-1e-11970.66% (317) O-succinylbenzoate synthase
M. avium 104MAV_4590-1e-14581.99% (322) O-succinylbenzoate synthase
M. smegmatis MC2 155MSMEG_1103-1e-13775.39% (321) O-succinylbenzoate synthase
M. thermoresistible (build 8)TH_0152menC1e-13273.98% (319) PROBABLE MUCONATE CYCLOISOMERASE MENC (CIS,CIS-MUCONATE
M. ulcerans Agy99MUL_0652menC0.099.39% (327) O-succinylbenzoate synthase
M. vanbaalenii PYR-1Mvan_0971-1e-13576.43% (314) O-succinylbenzoate synthase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_0899|M.marinum_M               ------------------------MIPGPATLPDLLDRLHVVALPMRVRF
MUL_0652|M.ulcerans_Agy99           ------------------------MIPGPATLPDLLDRLQVVALPMRVRF
Mb0568|M.bovis_AF2122/97            ------------------------MIPVLPPLEALLDRLYVVALPMRVRF
Rv0553|M.tuberculosis_H37Rv         ------------------------MIPVLPPLEALLDRLYVVALPMRVRF
MAV_4590|M.avium_104                ------------------------MIP---PLQDLLDRLHVVALPMRVRF
MLBr_02268|M.leprae_Br4923          ------------------------MIP---TLTELLDRLHVVALPMRVRF
Mflv_5268|M.gilvum_PYR-GCK          ----------------------------MADLADILDRLHVVALPMRVRF
Mvan_0971|M.vanbaalenii_PYR-1       MGRRPRRRVRSRGRAGACAFRLLRHDEAVPELADVLDRLHVVALPMRVRF
MSMEG_1103|M.smegmatis_MC2_155      ------------------------MTNGVPALDDILERLHVVALPMRVRF
TH_0152|M.thermoresistible__bu      ---------------------VGDTGPVMPTLDELLERLRVVALPMRVPF
MAB_3935c|M.abscessus_ATCC_199      --------------------------MELPVLDDVLDRLHVVALPMRVRF
                                                                   *  :*:** ******** *

MMAR_0899|M.marinum_M               RGITTREVALIEGPSGWGEFGAFLEYQPPEAAAWLASAIDAAYGQPPPVR
MUL_0652|M.ulcerans_Agy99           RGITTREVALIEGPSGWGEFGAFLEYQPPEAAAWLASAIDAAYGQPPPVR
Mb0568|M.bovis_AF2122/97            RGITTREVALIEGPAGWGEFGAFVEYQSAQACAWLASAIETAYCAPPPVR
Rv0553|M.tuberculosis_H37Rv         RGITTREVALIEGPAGWGEFGAFVEYQSAQACAWLASAIETAYCAPPPVR
MAV_4590|M.avium_104                RGITTREVALIDGPAGWGEFGAFVEYGPPEAAHWLASAVESAYRPAPPVR
MLBr_02268|M.leprae_Br4923          RGITTREVALIDGPAGWGEFGAFLEYQPLEASAWLVAGIEAAYGEPPEGR
Mflv_5268|M.gilvum_PYR-GCK          RGITTREVALIDGPAGWGEFGPFLEYEPPEAAHWLASGVAAAYRPMPEVR
Mvan_0971|M.vanbaalenii_PYR-1       RGITTRELALIDGPAGWGEFGAFVEYRPAEAAHWLAAGIEAAYRPLPEVR
MSMEG_1103|M.smegmatis_MC2_155      RGITVRELALIDGPAGWGEFGAFVEYEPPEAAAWLSSALEAAYRPAPAAL
TH_0152|M.thermoresistible__bu      RGVTVREVALIEGPVAWGEFGAFPEYGPAEAAAWLAAGIEAAFKSPPLIR
MAB_3935c|M.abscessus_ATCC_199      RGITTREVALIDGPAGWGEFGAFPEYQPAEASAWLSAAIEAAYRALPTPR
                                    **:*.**:***:** .*****.* ** . :*. ** :.: :*:   *   

MMAR_0899|M.marinum_M               RGRIPINATVPAVPPAQVPELLARFPGARTAKVKVAEPGQTLASDVERVN
MUL_0652|M.ulcerans_Agy99           RGRIPINATVPAVPPAQVPELLARFPGARTAKVKVAEPGQTLASDVERVN
Mb0568|M.bovis_AF2122/97            RDRVPINATVPAVAAAQVGEVLARFPGARTAKVKVAEPGQSLADDIERVN
Rv0553|M.tuberculosis_H37Rv         RDRVPINATVPAVAAAQVGEVLARFPGARTAKVKVAEPGQSLADDIERVN
MAV_4590|M.avium_104                RDRIPINATVPAVPAAAVPDVLARFPGARTAKVKVAEPGQTLADDVARVN
MLBr_02268|M.leprae_Br4923          RDRIPINATVPAVSATQVPEVLARFPGVRTAKVKVAEPGQNLADDVDRVN
Mflv_5268|M.gilvum_PYR-GCK          RARIPINATVPAVPADAVPDVLVRFPGARTAKVKVAEPGHTLADDVARVN
Mvan_0971|M.vanbaalenii_PYR-1       RPRIPINATVPAVAAHDVPGVLARFPGVRTAKVKVAEPGQTLADDVARVN
MSMEG_1103|M.smegmatis_MC2_155      RDRVPINATVPAVSAERVPEVLARFPGARTAKVKVAEPGQSLADDVARVN
TH_0152|M.thermoresistible__bu      RHRIPINATVPAVPAQRVPEVLSRFPGARTAKVKVAEPGQTLTDDVARVN
MAB_3935c|M.abscessus_ATCC_199      RDRIPVNATVPAVTAADVPEVLSRFPGAQTAKVKVAEPGQTLDEDVARVE
                                    * *:*:*******..  *  :* ****.:**********:.* .*: **:

MMAR_0899|M.marinum_M               AVRALVPTVRVDANGGWSVDQAAQAAVALTADGPLEYLEQPCATVGELAE
MUL_0652|M.ulcerans_Agy99           AVRALVPTVRVDANGGWSVDQAAQAAVALTADGPLEYLEQPCATVGELAE
Mb0568|M.bovis_AF2122/97            AVRELVPMVRVDANGGWGVAEAVAAAAALTADGPLEYLEQPCATVAELAE
Rv0553|M.tuberculosis_H37Rv         AVRELVPMVRVDANGGWGVAEAVAAAAALTADGPLEYLEQPCATVAELAE
MAV_4590|M.avium_104                AVRDLVPTVRVDANGGWSVDEAARAARALSADGPLEYLEQPCATVGELAE
MLBr_02268|M.leprae_Br4923          AVRELVETVRVDANGGWSVEAAAQAAVALTADGPLEYLEQPCATVAELAA
Mflv_5268|M.gilvum_PYR-GCK          AVRAAGLTARVDANGGWTVEQAVAAAQALTADGALEYLEQPCRTVPELAE
Mvan_0971|M.vanbaalenii_PYR-1       AVRDAVPTVRVDANGGWTVDEAVAAARALTADGPLEYLEQPCRTVPELAE
MSMEG_1103|M.smegmatis_MC2_155      AVRESVPVVRVDANGGWSVDDAVEAAAALTADGELEYLEQPCATVEELAA
TH_0152|M.thermoresistible__bu      AVRELVPTVRVDVNGAWTVDEAVKAAAALTADGPLEYLEQPCATIAELAE
MAB_3935c|M.abscessus_ATCC_199      AVRARIRTVRVDANGGWTVAQAVHALTALTRDGALEYAEQPCATVEELAE
                                    ***     .***.**.* *  *. *  **: ** *** **** *: *** 

MMAR_0899|M.marinum_M               LRRR---IEVPIAADEAIRKAEDPLAVVRAGAADVAVLKVAPLGGVWALL
MUL_0652|M.ulcerans_Agy99           LRRR---IEVPIAADEAIRKAEDPLAVVRAGAADVAVLKVAPLGGVWALL
Mb0568|M.bovis_AF2122/97            LRRR---VDVPIAADESIRKAEDPLAVVRAQAADIAVLKVAPLGGISALL
Rv0553|M.tuberculosis_H37Rv         LRRR---VDVPIAADESIRKAEDPLAVVRAQAADIAVLKVAPLGGISALL
MAV_4590|M.avium_104                LRRRPDMPDVPIAADESIRKADDPLAVVRARAADIAVLKVAPLGGISALL
MLBr_02268|M.leprae_Br4923          LRRR---VDIPIAADESIRKADDPLAVVRSHAADVAVLKVAPLGGIASFL
Mflv_5268|M.gilvum_PYR-GCK          VRRR---VDVPVAADESIRKADDPLHVVRSGAADVAVLKVAPLGGVQTML
Mvan_0971|M.vanbaalenii_PYR-1       VRRR---VDVPVAADESIRKAEDPLHVVRSGAADVAVLKVAPLGGVHAML
MSMEG_1103|M.smegmatis_MC2_155      LRAR---VDVPIAADESIRKAEDPLRVVRAHAADIAVLKVAPLGGVARML
TH_0152|M.thermoresistible__bu      LRRR---IDVPIAADESIRKADDPLRVVRAGAADIAVLKVAPLGGAYRLL
MAB_3935c|M.abscessus_ATCC_199      LRRR--LPGVPIAADESIRRASDPLRVAQARAADIAVLKVAPLGGVHALL
                                    :* *     :*:****:**:*.*** *.:: ***:**********   :*

MMAR_0899|M.marinum_M               DIAAQIDIPVVISSALDSAVGIAAGLSAAAALPQLQHACGLGTGGLFVED
MUL_0652|M.ulcerans_Agy99           DIAAQIDIPVVISSALDSAVGIAAGLSAAAALPQLQHACGLGTGGLFVED
Mb0568|M.bovis_AF2122/97            DIAARIAVPVVVSSALDSAVGIAAGLTAAAALPELDHACGLGTGGLFEED
Rv0553|M.tuberculosis_H37Rv         DIAARIAVPVVVSSALDSAVGIAAGLTAAAALPELDHACGLGTGGLFEED
MAV_4590|M.avium_104                EIAARIDIPVVISSALDSAVGIAAGLTAAAALPVLGHACGLGTGGLFVED
MLBr_02268|M.leprae_Br4923          AIAAQIDIPVVVSSALDSVVGITAGLIAAAALPELDYACGLGTGRLFVAD
Mflv_5268|M.gilvum_PYR-GCK          DIAAQIDIPVVVSSALDTAVGIGAGLVAAGCLPRLEHACGLGTGSLFVDD
Mvan_0971|M.vanbaalenii_PYR-1       DIAAQIDIPVVVSSALDSAVGIGVGLVAAGSLPTLDHACGLGTGGLFVDD
MSMEG_1103|M.smegmatis_MC2_155      DIAAQIDIPIVVSSALDSSVGIGRGLLAAAALPELRHACGLGTGGLFVDD
TH_0152|M.thermoresistible__bu      EIATAIDIPIVVSSALDTAVGIGRGLLAAAALPQLNHACGLGTGRLFVED
MAB_3935c|M.abscessus_ATCC_199      EIAARIGMPAVISSALDSAVGIGIGLRAAAALPELDHACGLGTGGFFLAD
                                     **: * :* *:*****: ***  ** **..** * :******* :*  *

MMAR_0899|M.marinum_M               VAEPAIPVDGALAPQRVVPDPARLRALGAAPDRRQWWIDRIKACYPLLYR
MUL_0652|M.ulcerans_Agy99           VAEPAIPVDGALAPQRVAPDPARLRALGAAPDRRQWWIDRIKACYPLLYR
Mb0568|M.bovis_AF2122/97            VAEPAAPVDGFLAVARTTPDPARLQALGAPPQRRQWWIDRVKACYSLLVP
Rv0553|M.tuberculosis_H37Rv         VAEPAAPVDGFLAVARTTPDPARLQALGAPPQRRQWWIDRVKACYSLLVP
MAV_4590|M.avium_104                VADVAAPVDGALPVGPVTPDPARLRALAAPPQRRQWWIDRVTACHGLLVP
MLBr_02268|M.leprae_Br4923          VAEPMLPVDGFLPVGPVTPDPARLQALGTPPARRQWWIDRVKTCYSLLVP
Mflv_5268|M.gilvum_PYR-GCK          VAEPRTPVDGYLPAAAVTPDPARITALAASDDRRQWWIDRVRACYPLMS-
Mvan_0971|M.vanbaalenii_PYR-1       VAAPVVPVDGYLPAAPVTPDLDRIAALAAPPDRRQWWIARVRECFPLVS-
MSMEG_1103|M.smegmatis_MC2_155      VAEPRVPVDGCLAVEPAVPDPARLAALAAPEPRRQWWIDRVCACHALI--
TH_0152|M.thermoresistible__bu      VAEPLELVDGHLPAAPVRPDPQRVLELAAPPDRRRWWMDRTRECFALLET
MAB_3935c|M.abscessus_ATCC_199      VADVPPVVDGHLPVTSCTPDPARLAALAVPADRLDRWRRRVADCHALLNR
                                    **     *** *.     **  *:  *...  *   *  *   *. *:  

MMAR_0899|M.marinum_M               RSGD----------
MUL_0652|M.ulcerans_Agy99           RSGD----------
Mb0568|M.bovis_AF2122/97            SFG-----------
Rv0553|M.tuberculosis_H37Rv         SFG-----------
MAV_4590|M.avium_104                SSG-----------
MLBr_02268|M.leprae_Br4923          CAGDQSGLRRPRDR
Mflv_5268|M.gilvum_PYR-GCK          --------------
Mvan_0971|M.vanbaalenii_PYR-1       --------------
MSMEG_1103|M.smegmatis_MC2_155      --------------
TH_0152|M.thermoresistible__bu      --------------
MAB_3935c|M.abscessus_ATCC_199      --------------