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ARYGPPDDFHSQPTQYGGYPAGGRPPAGPPPSRPAGPQSGPPPQAPPGPDSLSPSEQFASAEGYDQEKPE SEPKPWYRNPVTLTGWALLVMILIALIVYGIIELISDRQGTGNPSTTTPSTTTSTTTAETTTTTPPTTTT TTVAPATTPRVQPPPQQPTHPPTHRFPHLPPLPSVITIPGVPTTITLPPHLP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0619 | - | - | 100% (193) | hypothetical protein MMAR_0619 |
| M. marinum M | MMAR_0618 | - | 2e-23 | 33.92% (227) | hypothetical protein MMAR_0618 |
| M. marinum M | MMAR_4169 | pknH_1 | 7e-12 | 30.37% (191) | transmembrane serine/threonine-protein kinase H, PknH_1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2535 | - | 3e-11 | 33.55% (152) | proline rich membrane protein |
| M. gilvum PYR-GCK | Mflv_0270 | - | 2e-16 | 32.86% (210) | hypothetical protein Mflv_0270 |
| M. tuberculosis H37Rv | Rv2507 | - | 3e-11 | 33.55% (152) | proline rich membrane protein |
| M. leprae Br4923 | MLBr_00877 | mmpS3 | 3e-05 | 43.48% (46) | hypothetical protein MLBr_00877 |
| M. abscessus ATCC 19977 | MAB_4291 | - | 3e-12 | 33.77% (154) | hypothetical protein MAB_4291 |
| M. avium 104 | MAV_4815 | - | 6e-39 | 45.81% (203) | hypothetical protein MAV_4815 |
| M. smegmatis MC2 155 | MSMEG_0700 | - | 8e-17 | 35.07% (134) | hypothetical protein MSMEG_0700 |
| M. thermoresistible (build 8) | TH_2748 | - | 6e-20 | 35.42% (192) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0584 | - | 1e-113 | 96.89% (193) | hypothetical protein MUL_0584 |
| M. vanbaalenii PYR-1 | Mvan_0627 | - | 1e-13 | 42.86% (98) | hypothetical protein Mvan_0627 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0619|M.marinum_M --------------------------------------------------
MUL_0584|M.ulcerans_Agy99 --------------------------------------------------
MAV_4815|M.avium_104 --------------------------------------------------
Mflv_0270|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0627|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2748|M.thermoresistible__bu --------------------------------------------------
MSMEG_0700|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4291|M.abscessus_ATCC_1997 MANALGLSIGATQLVATPDDPQSQPVVRSSILTLHEDGPPEVGVPSQPGL
Mb2535|M.bovis_AF2122/97 --------------------------------------------------
Rv2507|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00877|M.leprae_Br4923 --------------------------------------------------
MMAR_0619|M.marinum_M --------------------------------------------------
MUL_0584|M.ulcerans_Agy99 --------------------------------------------------
MAV_4815|M.avium_104 --------------------------------------------------
Mflv_0270|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0627|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2748|M.thermoresistible__bu --------------------------------------------------
MSMEG_0700|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4291|M.abscessus_ATCC_1997 TLTGFVGRVGDPVGIVAADGSVHRAEWALTEAMRVLIADAVSSANFTAPP
Mb2535|M.bovis_AF2122/97 --------------------------------------------------
Rv2507|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00877|M.leprae_Br4923 --------------------------------------------------
MMAR_0619|M.marinum_M --------------------------------------------------
MUL_0584|M.ulcerans_Agy99 --------------------------------------------------
MAV_4815|M.avium_104 --------------------------------------------------
Mflv_0270|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0627|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2748|M.thermoresistible__bu --------------------------------------------------
MSMEG_0700|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4291|M.abscessus_ATCC_1997 VLSASIPAHWSPQTVSTLRDAIDRVPAFAPGGRQLKLIPDARAALEALAA
Mb2535|M.bovis_AF2122/97 --------------------------------------------------
Rv2507|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00877|M.leprae_Br4923 --------------------------------------------------
MMAR_0619|M.marinum_M --------------------------------------------------
MUL_0584|M.ulcerans_Agy99 --------------------------------------------------
MAV_4815|M.avium_104 --------------------------------------------------
Mflv_0270|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0627|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2748|M.thermoresistible__bu --------------------------------------------------
MSMEG_0700|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4291|M.abscessus_ATCC_1997 GPGTPDRGVVVVCDLGGSGSSITLADAARGFQQIGQTIRFADFSGQQIDQ
Mb2535|M.bovis_AF2122/97 --------------------------------------------------
Rv2507|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00877|M.leprae_Br4923 --------------------------------------------------
MMAR_0619|M.marinum_M --------------------------------------------------
MUL_0584|M.ulcerans_Agy99 --------------------------------------------------
MAV_4815|M.avium_104 --------------------------------------------------
Mflv_0270|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0627|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2748|M.thermoresistible__bu --------------------------------------------------
MSMEG_0700|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4291|M.abscessus_ATCC_1997 MLLTQVLTDLNQDPEGTTSVGALTRLRDQCRLAKERLSGDTATSVPVQLP
Mb2535|M.bovis_AF2122/97 --------------------------------------------------
Rv2507|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00877|M.leprae_Br4923 --------------------------------------------------
MMAR_0619|M.marinum_M --------------------------------------------------
MUL_0584|M.ulcerans_Agy99 --------------------------------------------------
MAV_4815|M.avium_104 --------------------------------------------------
Mflv_0270|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0627|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2748|M.thermoresistible__bu --------------------------------------------------
MSMEG_0700|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4291|M.abscessus_ATCC_1997 GITTDVRLTRAELEGHLRGPLSNLINAIQDTVERNGIHPANITAVASVGG
Mb2535|M.bovis_AF2122/97 --------------------------------------------------
Rv2507|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00877|M.leprae_Br4923 --------------------------------------------------
MMAR_0619|M.marinum_M --------------------------------------------------
MUL_0584|M.ulcerans_Agy99 --------------------------------------------------
MAV_4815|M.avium_104 --------------------------------------------------
Mflv_0270|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0627|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2748|M.thermoresistible__bu --------------------------------------------------
MSMEG_0700|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4291|M.abscessus_ATCC_1997 GASIPLVTQQLSERMRVPVITAPQPQLAAARGVALLATRPDLPPQDATAM
Mb2535|M.bovis_AF2122/97 --------------------------------------------------
Rv2507|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00877|M.leprae_Br4923 ------------------------------------------MSGPNPPG
MMAR_0619|M.marinum_M ------------------------------------MARYGPPDDFHSQP
MUL_0584|M.ulcerans_Agy99 ------------------------------------MARYGPPDDFHSQP
MAV_4815|M.avium_104 ------------MRVPTPRLPIGISGLAGAVSTIGAVASNGPRDEFHNQP
Mflv_0270|M.gilvum_PYR-GCK ------------------------------------MARYGDSDDPN-YS
Mvan_0627|M.vanbaalenii_PYR-1 ------------------------------------MARYGDSDDQNYYS
TH_2748|M.thermoresistible__bu ------------------------------------VAVSRPPEDPSNYS
MSMEG_0700|M.smegmatis_MC2_155 ------------------------------------MANNYSDDEPTQYA
MAB_4291|M.abscessus_ATCC_1997 RPVEQPPGDATMMRPVPTGTGTFAAPVAAAANEEPELAWSQDDSAPDLAP
Mb2535|M.bovis_AF2122/97 --------MNDPRRPQRFGPPLSGYGPTGPQVPPNPPTADPAYADQSPYA
Rv2507|M.tuberculosis_H37Rv --------MNDPRRPQRFGPPLSGYGPTGPQVPPNPPTADPAYADQSPYA
MLBr_00877|M.leprae_Br4923 RENEESDSGNELSGELDPHNGVESVDELVPVPDSDLVTASDHTSETEVYS
: .
MMAR_0619|M.marinum_M TQYGGYPAGGRPPAGPPPSRPAGPQSGPPPQAPPGPDSLSPSEQFASAEG
MUL_0584|M.ulcerans_Agy99 TQYGGYPAGGRPPAGAPPSRPAGPQSGPPPQAPPGPDSPNPSVQFASAEG
MAV_4815|M.avium_104 TQHADFGMSQQPPTGELP----------PPGFPP--DRPEGFEQPGNVDP
Mflv_0270|M.gilvum_PYR-GCK DDDPTQLSNY----------------------------------AYGDYE
Mvan_0627|M.vanbaalenii_PYR-1 DDEPTQLSNYGT--------------------------------GYGEYD
TH_2748|M.thermoresistible__bu DSEPTAYSDYTAGGSGGYV----------------------PGYGGGEYG
MSMEG_0700|M.smegmatis_MC2_155 HSYG---GDYGA--------------------------------DYGAYP
MAB_4291|M.abscessus_ATCC_1997 LQETGYQSGYTVDLDDEYQGP-----------TEATTARPELRFSHGPYA
Mb2535|M.bovis_AF2122/97 STYGGYVSPPWSPGGPPPRPPQWPPG--PHEASPTQQLPQYWQYDQPPPG
Rv2507|M.tuberculosis_H37Rv STYGGYVSPPWSPGGPPPRPPQWPPG--PHEASPTQQLPQYWQYDQPPPG
MLBr_00877|M.leprae_Br4923 QAYSAPEAEHFTAVPYVPADLR--------------------LYDYDESS
MMAR_0619|M.marinum_M YDQEKPESEPKPWYRNP------VTLTGWALLVMILIALIVYG-------
MUL_0584|M.ulcerans_Agy99 YDQEKPEAEPKPWYRNP------VTLTGWALLVMILIALIVYG-------
MAV_4815|M.avium_104 FDQ---EAEPTPWYRRP------AMLIAWVVSVVVLIGLIVFG-------
Mflv_0270|M.gilvum_PYR-GCK QAPPPDAEPPVPWYRKP------AALVGLGALGAVLIALIVFG-------
Mvan_0627|M.vanbaalenii_PYR-1 QSP-TEADSATPWYRKP------VALVSFGAVGALLIALVVFG-------
TH_2748|M.thermoresistible__bu GPPGPPEEPPVPWYRKP------AALVAFGALGAVLLGLIVFA-------
MSMEG_0700|M.smegmatis_MC2_155 PPDQPPAPEPVPWYRKP------AALVGLGALGALIVALVIYA-------
MAB_4291|M.abscessus_ATCC_1997 DEDDYDDYPPLPWYRRPLVWFIAAAAVAGIAFTGMMVSLTSSE-------
Mb2535|M.bovis_AF2122/97 GFPPDGLTPPPPQGPRTPRWLWFAAGSAVLLVVALVIALVIANGSVKKQT
Rv2507|M.tuberculosis_H37Rv GFPPDGLTPPPPQGPRTPRWLWFAAGSAVLLVVALVIALVIANGSVKKQT
MLBr_00877|M.leprae_Br4923 VYDEPGAAPRWPWVVGVAAILAAISLVVSVSLLFTRTDTSKLSTPTTGRS
*
MMAR_0619|M.marinum_M IIELISDRQGTGN-PSTTTPSTTTSTTT----------------AETTTT
MUL_0584|M.ulcerans_Agy99 IIELISDRQGTGN-PSTTTPSTTTSTTT----------------AETATT
MAV_4815|M.avium_104 VIELIGGQQGVSHVPKSTTSTTTTATTT----------------TTTTTT
Mflv_0270|M.gilvum_PYR-GCK LAKAITGDSDSETTPTSSLTPVTTTSAPAAVPP----------ATVTETA
Mvan_0627|M.vanbaalenii_PYR-1 LARAITGDSTSDTTTTTPLTPVTTTSAPAVVPP----------ATVTETA
TH_2748|M.thermoresistible__bu LIRLTSGDDASSETATTTTTTTTTTGAPVAPPP----------ATVTQTV
MSMEG_0700|M.smegmatis_MC2_155 VIQLFSSDDSSSTTSTTTSTTSTTPVTTSQVAP----------VAPVPTR
MAB_4291|M.abscessus_ATCC_1997 SPAPATTTPSVNVVPSTGDAPAEPPPSPEPPPPPQT-------HTVTQSV
Mb2535|M.bovis_AF2122/97 AIEPLPPMPGPSPTRPTTTTPTPPSPSAAPAPTTTTGTPSETVAGAMQTV
Rv2507|M.tuberculosis_H37Rv AIEPLPPMPGPSPTRPTTTTPTPPSPSAAPAPTTTTGTPSETVAGAMQTV
MLBr_00877|M.leprae_Br4923 TPPVQDEITTVKPPPPSTETSTATETQTVTVTPLPPP------SATSTAV
: .. . . :
MMAR_0619|M.marinum_M TPPTTTTTTVAP-ATTPRVQPPPQQP----THPPTHRFPHLPPLPSVITI
MUL_0584|M.ulcerans_Agy99 TPPTTTTTTVAP-ATTPRVQPPPQQP----THPPTHRFPHLPPLPSVITI
MAV_4815|M.avium_104 TTTTPSSTSPGSSAEQPPAQQPSQQPGGGQTQQPSHHH-RLPQLPPVITI
Mflv_0270|M.gilvum_PYR-GCK SESATTTTEPTTTTTTTEPTTTTTTTTPTTTTTPSTSVSTSTSTSTVTQT
Mvan_0627|M.vanbaalenii_PYR-1 --TATTTTEPVTTTTTTEPTTTTTTTT-TTTTTPSTSVSTSTSTSTVTQT
TH_2748|M.thermoresistible__bu PPATTTPAEEPSPPPTTTQTPTTTTTTTTTTTTESP--TTTTTTETVTQT
MSMEG_0700|M.smegmatis_MC2_155 --TVTETSTPAQTTVTETATTTPPTTTTTTTAPPTTSTTVETSTSVVTST
MAB_4291|M.abscessus_ATCC_1997 QPPPPSPEPPPPPPPTTTTTTTPPTTTTTTTTTTTTTTTTTTTPTTTTTQ
Mb2535|M.bovis_AF2122/97 VYDVTGEGRAISITYMDSGNVIQTEFNVALPWRKEVSLSKSSLHPASVTI
Rv2507|M.tuberculosis_H37Rv VYDVTGEGRAISITYMDSGNVIQTEFNVALPWRKEVSLSKSSLHPASVTI
MLBr_00877|M.leprae_Br4923 PPSSVVPPPPTTPTTTVTTLTGPRQVTYSVTGTKAPGDIISVTYVDASGR
. .
MMAR_0619|M.marinum_M PGVPTTITLPPHLP------------------------------------
MUL_0584|M.ulcerans_Agy99 PGVPTTITLPPHLP------------------------------------
MAV_4815|M.avium_104 PQVPTVITVPPGLR------------------------------------
Mflv_0270|M.gilvum_PYR-GCK ETQTETVTEPPPAPPTP---------------------------------
Mvan_0627|M.vanbaalenii_PYR-1 ETQTETVTETP-APPAP---------------------------------
TH_2748|M.thermoresistible__bu ETETQTVTAPPDEGE-----------------------------------
MSMEG_0700|M.smegmatis_MC2_155 VTETTTVPEEEGGEQP----------------------------------
MAB_4291|M.abscessus_ATCC_1997 PTTTTTQPTSTSRPAITIPGLPPIPIGPRN--------------------
Mb2535|M.bovis_AF2122/97 VNIGHNVTCSVTVAGVQVRQRTGAGLTICDAPS-----------------
Rv2507|M.tuberculosis_H37Rv VNIGHNVTCSVTVAGVQVRQRTGAGLTICDAPS-----------------
MLBr_00877|M.leprae_Br4923 RRTQHNVYIPWSMTVTPISQSDVGSVEAFSLFRVSKLNCLITTSDGTVLS
MMAR_0619|M.marinum_M -----------
MUL_0584|M.ulcerans_Agy99 -----------
MAV_4815|M.avium_104 -----------
Mflv_0270|M.gilvum_PYR-GCK -----------
Mvan_0627|M.vanbaalenii_PYR-1 -----------
TH_2748|M.thermoresistible__bu -----------
MSMEG_0700|M.smegmatis_MC2_155 -----------
MAB_4291|M.abscessus_ATCC_1997 -----------
Mb2535|M.bovis_AF2122/97 -----------
Rv2507|M.tuberculosis_H37Rv -----------
MLBr_00877|M.leprae_Br4923 SNSNDAPQTSC